Body Water Content in Cyanotic Congenital Heart Disease

This study has been completed.
Information provided by:
National Center for Research Resources (NCRR) Identifier:
First received: January 18, 2000
Last updated: June 23, 2005
Last verified: December 2003
Adults with cyanotic congenital heart disease have elevated levels of plasma proatrial natruretic peptide (proANP) which most likely results in chronic dehydration, leading to reduced oxygen transport to tissues and shortness of breath with activity. The purpose of this study is to characterize adults with cyanotic congenital heart defects with respect to their body composition (water and fat-free mass) and resting metabolic rates. The study consists of several measures of how much body water, fat and lean tissue a subject has, and measures the number of calories the subject's body uses at rest. Adult subjects with cyanotic congenital heart disease will be recruited along with healthy noncyanotic control subjects matched for age, gender, and body weight.

Heart Defects, Congenital

Study Type: Observational
Study Design: Observational Model: Case Control

Resource links provided by NLM:

Further study details as provided by National Center for Research Resources (NCRR):


Ages Eligible for Study:   17 Years to 60 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Resting blood pressure below 140/90
  Contacts and Locations
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Please refer to this study by its identifier: NCT00000107

United States, Vermont
University of Vermont
Burlington, Vermont, United States, 05401
Sponsors and Collaborators
National Center for Research Resources (NCRR)
  More Information

No publications provided Identifier: NCT00000107     History of Changes
Other Study ID Numbers: NCRR-M01RR00109-0737, M01RR00109
Study First Received: January 18, 2000
Last Updated: June 23, 2005
Health Authority: United States: Federal Government

Keywords provided by National Center for Research Resources (NCRR):
Cyanotic Congenital Heart Disease

Additional relevant MeSH terms:
Congenital Abnormalities
Heart Defects, Congenital
Cardiovascular Abnormalities
Cardiovascular Diseases
Heart Diseases processed this record on November 25, 2015