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122 studies found for:    vemurafenib
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Rank Status Study
1 Active, not recruiting BRAF Inhibitor, Vemurafenib, in Patients With Relapsed or Refractory Hairy Cell Leukemia
Condition: Hairy Cell Leukemia
Intervention: Drug: Vemurafenib
2 Recruiting Phase 2 Study Assessing Secured Access to Vemurafenib for Patients With Tumors Harboring BRAF Genomic Alterations
Conditions: Solid Tumors;   Hematologic Cancers;   Metastatic Cancers
Intervention: Drug: Vemurafenib
3 Terminated The Effects of Vemurafenib + Cobimetinib on Immunity in Patients With Melanoma
Condition: Melanoma
Intervention: Drug: Vemurafenib
4 Recruiting An Extension (Rollover) Study of Vemurafenib in Participants With BRAF V600 Mutation-Positive Malignancies Previously Enrolled in an Antecedent Vemurafenib Protocol
Condition: Neoplasms
Intervention: Drug: Vemurafenib
5 Recruiting Vemurafenib in Children With Recurrent/Refractory BRAFV600E-mutant Gliomas
Condition: Pediatric Recurrent/Refractory BRAFV600E-mutant Gliomas
Intervention: Drug: Vemurafenib
6 Completed Enhancing Radioiodine Incorporation Into BRAF Mutant Thyroid Cancers With the Combination of Vemurafenib and KTN3379
Condition: Thyroid Cancer
Interventions: Biological: KTN3379;   Drug: vemurafenib
7 Completed
Has Results
Phase 2 Study of Neoadjuvant Vemurafenib in Melanoma Patients With Untreated Brain Metastases
Condition: Melanoma
Intervention: Drug: Vemurafenib
8 Recruiting Study of Neo-adjuvant Use of Vemurafenib Plus Cobimetinib for BRAF Mutant Melanoma With Palpable Lymph Node Metastases
Condition: Melanoma
Interventions: Drug: Vemurafenib;   Drug: Cobimetinib
9 Active, not recruiting
Has Results
A Study of Vemurafenib (Zelboraf) in Chinese Participants With BRAF V600 Mutation-Positive Unresectable or Metastatic Melanoma
Condition: Malignant Melanoma
Intervention: Drug: Vemurafenib
10 Recruiting Bioavailability Study of Vemurafenib in Patients With BRAF^V600 Mutation-Positive Malignancies
Condition: Malignant Melanoma, Cancer
Interventions: Drug: Vemurafenib;   Drug: ^14 C-labeled vemurafenib
11 Recruiting Vemurafenib and Cobimetinib Combination in BRAF Mutated Melanoma With Brain Metastasis
Condition: Malignant Melanoma
Intervention: Drug: Cobimetinib + Vemurafenib combination treatment
12 Completed
Has Results
A Pharmacokinetics (PK) Study to Investigate the Effect of Rifampin on PK of Vemurafenib (Zelboraf)
Condition: Malignant Melanoma, Neoplasms
Interventions: Drug: Rifampin;   Drug: Vemurafenib
13 Withdrawn Trial of Vemurafenib and Cobimetinib in Patients With Advanced BRAFV600 Mutant Melanoma
Condition: Melanoma
Interventions: Drug: Cobimetinib;   Drug: Vemurafenib
14 Recruiting ML29255 Neoadjuvant Vemurafenib and Cobimetinib Melanoma
Condition: Stage IIIB-C Melanoma
Intervention: Drug: Vemurafenib and Cobimetinib
15 Active, not recruiting Study of Vemurafenib, Carboplatin, and Paclitaxel
Condition: Advanced Cancers
Interventions: Drug: Vemurafenib;   Drug: Carboplatin;   Drug: Paclitaxel
16 Terminated Study of PX-866 and Vemurafenib in Patients With Advanced Melanoma
Condition: Advanced BRAF-mutant Cancers
Interventions: Drug: PX-866;   Drug: vemurafenib
17 Terminated
Has Results
BRIM-P: A Study of Vemurafenib in Pediatric Patients With Stage IIIC or Stage IV Melanoma Harboring BRAFV600 Mutations
Condition: Malignant Melanoma
Intervention: Drug: vemurafenib
18 Completed Vemurafenib + Fotemustine to Treat Advanced Melanoma Patients With V600BRAF Mutation Recurred While on Vemurafenib
Condition: Malignant Melanoma Stage IV
Intervention: Drug: Fotemustine + Vemurafenib
19 Completed
Has Results
A Study of Vemurafenib (RO5185426) in Participants With Metastatic or Unresectable Papillary Thyroid Cancer Positive for the BRAF V600 Mutation
Condition: Neoplasms
Intervention: Drug: Vemurafenib
20 Terminated Phase II Study of Cobimetinib in Combination With Vemurafenib in Active Melanoma Brain Metastases
Condition: Active Melanoma Brain Metastases
Interventions: Drug: Cobimetinib;   Drug: Vemurafenib

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Study has passed its completion date and status has not been verified in more than two years.