| 1 |
NCT01285349 |
Completed |
HIV/STI Prevention for Drug-Involved Couples |
- Sexually Transmitted Diseases
|
- Behavioral: Couple HIV/STI prevention intervention
- Behavioral: Couple-based HIV prevention
- Behavioral: Individual HIV/STI prevention
- Behavioral: Couple Wellness Promotion
|
Interventional |
Phase 2 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- number of unprotected acts of intercourse
- cumulative incidence of biologically confirmed STIs (i.e., Chlamydia, gonorrhea, and Trichomoniasis
|
564 |
All |
18 Years to 40 Years (Adult) |
NCT01285349 |
AAAA6653 |
Connect II |
November 2005 |
October 2009 |
October 2009 |
January 28, 2011 |
January 28, 2011 |
|
- Social Intervention Group/Columbia University School of Social Work
New York, New York, United States
|
| 2 |
NCT00978848 |
Completed |
Non-Invasive Sexually Transmitted Disease Testing in Women Seeking Emergency Contraception or Urine Pregnancy Testing |
- Trichomonas Vaginitis
- Chlamydia Trachomatis
- Neisseria Gonorrhoeae Infection
|
|
Observational |
|
- University of Pittsburgh
- Gen-Probe, Incorporated
|
Other / Industry |
- Observational Model: Case-Only
- Time Perspective: Cross-Sectional
|
|
305 |
Female |
15 Years and older (Child, Adult, Senior) |
NCT00978848 |
PRO8120077 |
|
November 2009 |
April 2010 |
April 2010 |
September 17, 2009 |
May 18, 2016 |
|
- Magee-Womens Hospital of UPMC
Pittsburgh, Pennsylvania, United States
|
| 3 |
NCT00922038 |
Completed |
Rewarding Sexually Transmitted Infection (STI) Prevention and Control in Tanzania |
- Sexually Transmitted Diseases
|
|
Interventional |
Not Applicable |
- University of California, Berkeley
- World Bank
- Health Effects Institute
- (and 4 more...)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Prevalence of sexually transmitted infections measured in laboratory testing (Chlamydia, Gonorrhea, Syphilis, Trichomonas, Mycoplasma genitalium, HSV-2, HIV)
|
2411 |
All |
16 Years and older (Child, Adult, Senior) |
NCT00922038 |
025202 |
RESPECT |
February 2009 |
|
|
June 17, 2009 |
June 17, 2009 |
|
|
| 4 |
NCT01589965 |
Unknown † |
The Impact of Short-term Financial Incentives on Sexual Behavior and HIV Incidence in Lesotho |
- AIDS/HIV PROBLEM
- Sexually Transmitted Diseases
|
- Behavioral: Financial incentive through lotteries
|
Interventional |
Early Phase 1 |
- Bocconi University
- World Bank
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Prevention
|
- HIV prevalence
- STI prevalence (Chlamydia, Syphilis, Trichomoniasis)
|
5000 |
All |
18 Years to 45 Years (Adult) |
NCT01589965 |
100 |
|
February 2010 |
February 2010 |
June 2012 |
May 2, 2012 |
May 2, 2012 |
|
- Lucia Corno
London, United Kingdom
|
| 5 |
NCT02391233 |
Recruiting |
Multimedia WORTH With Black Drug-Involved Women on Probation |
- Sexually Transmitted Infections
- HIV
- Gonorrhea
- (and 3 more...)
|
- Behavioral: E-WORTH
- Behavioral: Streamlined HIV Testing
|
Interventional |
Not Applicable |
- Columbia University
- Fortune Society
- University of Pennsylvania
- (and 4 more...)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Prevention
|
- Change in cumulative incidence of biologically confirmed STIs (i.e., Chlamydia, gonorrhea and trichomonas.
- Change in the number of unprotected sex acts
- Change in cumulative incidence of biologically confirmed STIs (i.e., Chlamydia, gonorrhea and trichomonas as moderated by participant race, age and other socio-demographics and psychosocial client characteristics
- (and 5 more...)
|
460 |
Female |
18 Years and older (Adult, Senior) |
NCT02391233 |
AAAN8409
1R01DA038122-01 |
E-WORTH |
May 2015 |
January 2018 |
January 2019 |
March 18, 2015 |
January 31, 2017 |
|
- Columbia University
New York, New York, United States
|
| 6 |
NCT02291224 |
Active, not recruiting |
Development and Testing of a Clinic-Based Intervention to Increase Dual Protection Against Unintended Pregnancy and Sexually Transmitted Diseases (STDs) Among High Risk Female Teens |
- Pregnancy
- Sexually Transmitted Diseases
|
- Behavioral: Interactive multimedia platform
- Behavioral: Intervention arm counseling
- Behavioral: Standard of care counseling
|
Interventional |
Not Applicable |
- Centers for Disease Control and Prevention
- Emory University
- Grady Health System
|
U.S. Fed / Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Participant selection of an effective dual protection (DP) strategy
- Participant report of adherence to DP strategy
- Time to first biologic event (pregnancy or diagnosis with STI) in participants
- (and 6 more...)
|
710 |
Female |
14 Years to 19 Years (Child, Adult) |
NCT02291224 |
CDC-NCCDPHP-6588
DP12-001 |
2Gether |
March 2015 |
September 2018 |
September 2018 |
November 14, 2014 |
March 12, 2018 |
|
- Grady Health System Teen Services Clinic
Atlanta, Georgia, United States
|
| 7 |
NCT01784809 |
Completed |
The Multimedia HIV/STI Prevention for Drug-Involved Female Offenders |
- HIV
- Sexually Transmitted Infections
|
- Behavioral: Multimedia WORTH
- Behavioral: Traditional WORTH
- Behavioral: Wellness Promotion
|
Interventional |
Phase 2 |
- Columbia University
- Center for Court Innovation
- Bronx Community Solutions
- (and 2 more...)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- The proportion of condom protected acts of vaginal and anal intercourse
- Cumulative incidence of biologically confirmed STIs (Chlamydia, Gonorrhea and Trichomoniasis)
|
306 |
Female |
18 Years and older (Adult, Senior) |
NCT01784809 |
AAAD5608
R01DA025878 |
Project WORTH |
November 2009 |
March 2013 |
March 2013 |
February 6, 2013 |
February 27, 2014 |
|
- Columbia University School of Social Work
New York, New York, United States
|
| 8 |
NCT02552914 |
Active, not recruiting |
Evaluation of the Use of the Colli-Pee Device to Collect First-void Urine for Molecular Detection of STIs |
- Sexually Transmitted Diseases, Bacterial
|
|
Observational |
|
- Institute of Tropical Medicine, Belgium
- Novosanis NV
|
Other / Industry |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Detection of several STIs (CT/NG/MG/TV) on urine collected with the Colli-Pee device
- Easiness of use of the Colli-Pee device
- Willingness of future use of the Colli-Pee device
|
186 |
Male |
18 Years and older (Adult, Senior) |
NCT02552914 |
1027/15 |
Colli-Pee |
September 2015 |
June 2018 |
August 2018 |
September 17, 2015 |
March 1, 2018 |
|
- Institute of Tropical Medicine
Antwerp, Belgium
|
| 9 |
NCT02200224 |
Completed |
Clinical Utility of Rapid CT/NG Testing in the ED |
- Sexually Transmitted Diseases
|
|
Interventional |
Not Applicable |
- Johns Hopkins University
- National Institute for Biomedical Imaging and Bioengineering (NIBIB)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
|
- Overtreatment rate of CT/NG between the control and interventional groups
|
300 |
Female |
18 Years to 50 Years (Adult) |
NCT02200224 |
JHUIRB00026782
U54EB007958 |
|
April 2015 |
May 2016 |
May 2016 |
July 25, 2014 |
May 9, 2016 |
|
- Johns Hopkins Hospital
Baltimore, Maryland, United States
|
| 10 |
NCT00644163 |
Completed |
Effectiveness of a Risk Reduction Program in Preventing the Transmission of HIV and Sexually Transmitted Diseases in African-American Couples |
- HIV Infections
- Sexually Transmitted Disease
|
- Behavioral: Eban HIV/STD Risk Reduction Intervention
- Behavioral: Eban Health Promotion Intervention
|
Interventional |
Not Applicable |
- University of Pennsylvania
- National Institute of Mental Health (NIMH)
- University of California, Los Angeles
- (and 2 more...)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Primary Purpose: Prevention
|
- Self-reported proportion of condom-protected sexual intercourse
- Occurrence of STDs (chlamydia, gonorrhea, and trichomonas)
- Unprotected sex occurrence
- Number of sexual partners
|
1070 |
All |
18 Years and older (Adult, Senior) |
NCT00644163 |
U10MH078819
DAHBR 9A-ASGT |
|
November 2003 |
June 2007 |
June 2007 |
March 26, 2008 |
January 27, 2014 |
|
- UCLA
Los Angeles, California, United States - Emory University
Atlanta, Georgia, United States - Columbia University
New York, New York, United States - University of Pennsylvania
Philadelphia, Pennsylvania, United States
|
| 11 |
NCT01865383 |
Completed |
Microfinance and Health Intervention Trial for Youth in Dar es Salaam, Tanzania |
- Sexually Transmitted Infections
- Domestic Violence
|
- Behavioral: Microfinance and Health Leadership
|
Interventional |
Not Applicable |
- University of North Carolina, Chapel Hill
- National Institute of Mental Health (NIMH)
- Muhimbili University of Health and Allied Sciences
- American University
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Incidence of New Sexually Transmitted Infections
- Proportion of Men Reporting Perpetration of Physical, Sexual, or Psychological Partner Violence
|
2623 |
All |
15 Years to 99 Years (Child, Adult, Senior) |
NCT01865383 |
12-1111
1R01MH098690-01 |
|
July 2013 |
March 1, 2017 |
March 1, 2017 |
May 30, 2013 |
November 27, 2017 |
|
- University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States
|
| 12 |
NCT03407586 |
Completed |
STI Care Model to Reduce Genital Inflammation and HIV Risk in South African Women |
- HIV Prevention
- Sexually Transmitted Diseases
|
- Diagnostic Test: Point-of-care STI testing
|
Interventional |
Not Applicable |
- Centre for the AIDS Programme of Research in South Africa
- Johns Hopkins University
- National Institute of Allergy and Infectious Diseases (NIAID)
|
Other / NIH |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Changes in genital inflammation in women diagnosed with STIs after a diagnostic care intervention
- Prevalence of laboratory-diagnosed STIs in women presenting to the Prince Cyril Zulu Communicable Diseases Clinic, Durban, South Africa
- Validation of GeneXpert technology for STI testing against laboratory-based STI assays
- Acceptability of implementing expedited partner therapy among patients
|
267 |
Female |
18 Years to 40 Years (Adult) |
NCT03407586 |
CAPRISA 083
R21AI116759 |
|
May 15, 2016 |
February 1, 2017 |
February 1, 2017 |
January 23, 2018 |
January 26, 2018 |
|
- CAPRISA
Durban, KwaZulu-Natal, South Africa
|
| 13 |
NCT00710060 |
Completed |
Effectiveness of a Community-level HIV/STD Prevention Intervention in Promoting Safer Sexual Behaviors in High-risk Populations |
- HIV Infections
- Sexually Transmitted Diseases
|
- Behavioral: Community Popular Opinion Leader (C-POL)
- Behavioral: HIV/STD educational materials
|
Interventional |
Phase 3 |
- RTI International
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Prevention
|
- Frequency of unprotected sexual acts with nonspousal partners
- Overall observed incidence of sexually transmitted diseases (STDs) (e.g., chlamydia, gonorrhea, syphilis, trichomonas, HIV, or herpes simplex virus-2), as detected by biological specimens
- Increased exposure to HIV prevention messages, more STD treatment seeking, lower stigma regarding HIV and STDs, and lower substance abuse associated with sexual behavior in intervention group as compared to control group
|
18147 |
All |
18 Years to 49 Years (Adult) |
NCT00710060 |
U10MH061537
U10MH061499
U10MH061513
U10MH061536
U10MH061543
U10MH061544
DAHBR 9A-ASGT |
|
September 2002 |
August 2007 |
August 2007 |
July 3, 2008 |
November 4, 2013 |
|
- Fujian Institute of Health Education
Fuzhou, China - YRG Centre for AIDS Research and Education (YRGCARE)
Chennai, India - Universidad Peruana Cayetano Heredia
Lima, Peru - (and 2 more...)
|
| 14 |
NCT00213083 |
Completed |
Efficacy Study of the Vaginal Gel Carraguard to Prevent HIV Transmission |
- HIV Infections
- AIDS
- Sexually Transmitted Diseases
- HIV Seroconversion
|
- Drug: Carraguard (PC-515)
|
Interventional |
Phase 3 |
- Population Council
- United States Agency for International Development (USAID)
- Bill and Melinda Gates Foundation
|
Other / U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double
- Primary Purpose: Prevention
|
- Time to HIV seroconversion during trial participation (evaluated quarterly)
- Determine long-term safety based on the incidence of sexually transmitted infections (STI), Chlamydia, gonorrhoeae, trichomoniasis, and syphilis tests and the number of adverse events and serious adverse events
- Chlamydia, gonorrhoeae, trichomoniasis and syphilis tests are conducted at months 3, 6, 12, 18 and 24 and as clinically indicated
|
6203 |
Female |
16 Years to 40 Years (Child, Adult) |
NCT00213083 |
Population Council #322 |
|
April 2004 |
April 2007 |
April 2007 |
September 21, 2005 |
August 15, 2017 |
|
- Isipingo Clinic
Overport, Durban, South Africa - Empilisweni Clinic
Cape Town, South Africa - Setshaba Research Clinic, University of Limpopo - Medunsa Campus
Medunsa, South Africa
|
| 15 |
NCT02744586 |
Completed |
Zambia One Love Aim 3 Trial |
- HIV
- Sexually Transmitted Diseases
- Neglected Diseases
- Non-communicable Diseases
|
- Behavioral: Strengthening Our Vows (SOV)
- Behavioral: Good Health Package Plus (GHPP)
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Health Services Research
|
- HIV Incidence Rate
- Syphilis Incidence Rate
- Vaginal Trichomoniasis Incidence Rate
- (and 12 more...)
|
3450 |
All |
18 Years to 65 Years (Adult) |
NCT02744586 |
IRB00083001 |
|
January 2016 |
December 2016 |
December 2016 |
April 20, 2016 |
February 1, 2018 |
|
- Ndola Research Site
Ndola, Copperbelt, Zambia - Lusaka Research Site
Lusaka, Zambia
|
| 16 |
NCT03045809 |
Active, not recruiting |
Women's Improvement of Sexual Health (WISH) Demonstration Project |
- Sexually Transmitted Disease
- Bacterial Vaginosis
- Vaginal Candidiasis
- Urinary Tract Infections
|
- Diagnostic Test: Urogenital infection point-of-care tests
|
Observational |
|
- Janneke van de Wijgert
- Rinda Ubuzima, Rwanda
- Institute of Tropical Medicine, Belgium
- University of Liverpool
|
Other |
- Observational Model: Other
- Time Perspective: Cross-Sectional
|
- Feasibility of integrating point-of-care testing (monitoring & evaluation indicators)
- Feasibility of integrating point-of-care testing (client satisfaction and staff surveys)
- Performance of syndromic management with or without integration of point-of-care tests
- (and 2 more...)
|
705 |
Female |
18 Years and older (Adult, Senior) |
NCT03045809 |
UoL001208 |
WISH |
July 5, 2016 |
March 14, 2017 |
April 30, 2018 |
February 8, 2017 |
May 18, 2017 |
|
- Rinda Ubuzima
Kigali City, Kigali, Rwanda
|
| 17 |
NCT00207467 |
Completed |
Study to Improve Partner Services for STD Prevention |
- Trichomonas Vaginalis
- Urethritis
|
- Behavioral: Patient-delivered partner treatment
- Behavioral: Booklet-enhanced partner referral
|
Interventional |
Phase 2 |
- Centers for Disease Control and Prevention
- Tulane University
|
U.S. Fed / Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Index patient report of partner taking medicine at 6-8 weeks
- Index patient re-infection at 6-8 weeks
- Cost effectiveness outcomes
|
1500 |
All |
16 Years to 44 Years (Child, Adult) |
NCT00207467 |
CDC-NCHSTP-3196
CA# R30/CCR619143-01 |
|
December 2001 |
|
December 2004 |
September 21, 2005 |
September 21, 2005 |
|
- Delgado STD Clinic
New Orleans, Louisiana, United States - Orleans Women's Health Clinic
New Orleans, Louisiana, United States
|
| 18 |
NCT00706368 |
Unknown † |
Accuracy and Acceptability of Self-Diagnostic Methods for Vaginitis in Adolescent Females |
|
- Device: Point of care tests
|
Interventional |
Not Applicable |
- National Institute of Allergy and Infectious Diseases (NIAID)
|
NIH |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Sensitivity of self performed rapid trichomonas tests
- Acceptability of self testing for trichomonas
|
300 |
Female |
14 Years to 35 Years (Child, Adult) |
NCT00706368 |
K23AI063182 |
|
April 2006 |
October 2009 |
October 2009 |
June 27, 2008 |
June 27, 2008 |
|
- Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States
|
| 19 |
NCT01043081 |
Completed |
Sexually Transmitted Infections Among African American Women Who Have Sex With Women |
- Sexually Transmitted Infections
- HIV Infections
|
|
Observational |
|
- University of Mississippi Medical Center
- Mississippi State Department of Health
- University of Alabama at Birmingham
|
Other |
- Observational Model: Case-Only
- Time Perspective: Cross-Sectional
|
- Prevalence rates of sexually transmitted infections
- Associated sexual risk behaviors
|
300 |
Female |
18 Years and older (Adult, Senior) |
NCT01043081 |
2008-0143 |
WSW |
February 2009 |
December 2011 |
June 2012 |
January 6, 2010 |
May 11, 2016 |
|
- Crossroads Clinic
Jackson, Mississippi, United States
|
| 20 |
NCT01018095 |
Completed
Has Results |
Trichomonas Vaginalis Recurrence Among HIV+ Women |
- Trichomonas Infections
- HIV Infections
|
|
Interventional |
Phase 4 |
- Tulane University Health Sciences Center
- National Institute of Allergy and Infectious Diseases (NIAID)
- Tulane University
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- TV Culture Positive Result
|
270 |
Female |
18 Years and older (Adult, Senior) |
NCT01018095 |
543793
U19AI061972 |
|
May 2005 |
July 2009 |
August 2009 |
November 23, 2009 |
December 20, 2016 |
July 15, 2013 |
- HIV Outpatient Clinic
New Orleans, Louisiana, United States - NOAIDS
New Orleans, Louisiana, United States - Crossroads Clinic
Jackson, Mississippi, United States - (and 2 more...)
|
| 21 |
NCT00060463 |
Unknown † |
Increased Access to Emergency Contraceptive Pills |
- Pregnancy
- Sexually Transmitted Diseases
|
- Behavioral: Increased access to emergency contraceptive pills
|
Interventional |
Not Applicable |
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
|
1490 |
Female |
14 Years to 24 Years (Child, Adult) |
NCT00060463 |
1R01HD039907 |
|
October 2002 |
|
October 2005 |
May 7, 2003 |
June 24, 2005 |
|
- Planned Parenthood Mar Monte / University of California at San Francisco
Reno, Nevada, United States - Planned Parenthood of Central North Carolina
Durham, North Carolina, United States
|
| 22 |
NCT01728103 |
Terminated |
Prospective Collection of Female Specimens for Testing With Gen-Probe APTIMA (Registered Trademark) Assays |
- Chlamydia Infections
- Gonorrhea
- Trichomonas Infections
|
- Device: APTIMA® Trichomonas vaginalis & APTIMA® COMBO 2® Assays
|
Observational |
|
|
Industry |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Qualitative detection of ribosomal RNA from Chlamydia trachomatis and/or Neisseria gonorrhoeae (NG) and Trichomonas vaginalis (TV) to aid in the diagnosis of chlamydial and/or gonococcal and/or trichomonal urogenital disease
|
1336 |
Female |
16 Years and older (Child, Adult, Senior) |
NCT01728103 |
ATVTS-US12-001
AC2PS-US12-002
ATVPS-US12-001
ATVTS-US12-003 |
|
January 2013 |
July 2014 |
|
November 16, 2012 |
August 16, 2017 |
|
- Infectious Diseases STD Program University of Alabama at Birmingham
Birmingham, Alabama, United States - Medical Center for Clinical Research
San Diego, California, United States - Healthcare Clinical Data
North Miami, Florida, United States - (and 11 more...)
|
| 23 |
NCT02099760 |
Completed |
Cepheid Rectal Sample Validation Study |
- Gonorrhea
- Chlamydia
- Trichomonas
|
- Device: STD testing (GC/Ct/trich)
|
Observational |
|
- University of Pittsburgh
- National Institute of Allergy and Infectious Diseases (NIAID)
|
Other / NIH |
- Observational Model: Case-Only
- Time Perspective: Cross-Sectional
|
- Rectal Gonorrhea/Chlamydia testing result
- pharyngeal GC/Ct result
- Trichomonas Testing Results
|
402 |
All |
18 Years and older (Adult, Senior) |
NCT02099760 |
PRO13100170
5U01AI068633-04 |
|
December 2013 |
April 2015 |
April 2015 |
March 31, 2014 |
December 21, 2017 |
|
- Allegheny County Health Department Sexually Transmitted Diseases Clinic
Pittsburgh, Pennsylvania, United States - Magee-Womens Hospital of UPMC
Pittsburgh, Pennsylvania, United States
|
| 24 |
NCT00213018 |
Completed |
Safety, Acceptability and Preliminary Effectiveness of Carraguard™ (PC-515) in Preventing HIV/STI Transmission |
- HIV Infections
- Chlamydia Trachomatis
- Neisseria Gonorrhoeae
- (and 2 more...)
|
- Drug: Carraguard (PC-515)
|
Interventional |
Phase 2 |
- Population Council
- Bill and Melinda Gates Foundation
- FHI 360
- (and 5 more...)
|
Other / NIH / U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double
- Primary Purpose: Prevention
|
- Safety (toxicity): Symptoms 14 days after enrollment and monthly thereafter (6-12 months); tests (monthly) to detect change in vaginal flora;
- Compliance: collection of applicators and interview(monthly)
- Acceptability: interview (quarterly)
- Preliminary effectiveness: Swabs taken to test for sexually transmitted infections - gonorrhea, chlamydia, trichomoniasis (monthly) and blood drawn for syphilis and HIV testing (Month 1 and quarterly thereafter).
|
400 |
Female |
18 Years and older (Adult, Senior) |
NCT00213018 |
Population Council #210
R01AI045468-02 |
|
October 1999 |
|
January 2002 |
September 21, 2005 |
August 14, 2017 |
|
- University of Cape Town, Department of Community Health
Cape Town, South Africa - Medical University of Southern Africa
Soshanguve, South Africa
|
| 25 |
NCT00213057 |
Completed |
Safety and Acceptability of Carraguard™ Among HIV-negative Couples in Thailand |
- HIV Infections
- Chlamydia Trachomatis
- Nesseria Gonorrhea
- (and 2 more...)
|
- Drug: Carraguard (PC-515)
|
Interventional |
Phase 1 |
- Population Council
- Centers for Disease Control and Prevention
- Ministry of Health, Thailand
- (and 5 more...)
|
Other / U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double
- Primary Purpose: Prevention
|
- Safety (toxicity/local irritation): Genital exam and interview for signs and symptoms, 14-days after enrollment and monthly thereafter for 6 months; testing for bacterial vaginosis and candida (women) and balanitis (men) monthly.
- Acceptability: Interview about gel use to assess compliance (monthly) and acceptability (quarterly).
- Preliminary effectiveness: Swabs taken from women an urine specimens collected from men to test for sexually transmitted infections - gonorrhea, chlamydia, trichomoniasis (monthly) and for genital ulcer disease, if ulceration was detected; blood drawn
|
110 |
All |
18 Years and older (Adult, Senior) |
NCT00213057 |
Population Council #270
CDC Protocol #2968 |
|
June 2001 |
|
June 2002 |
September 21, 2005 |
August 14, 2017 |
|
- Chiang Rai Health Club
Chiang Rai, Thailand
|
| 26 |
NCT00213031 |
Completed |
Safety, Acceptability and Preliminary Effectiveness of PC-515 for Vaginal Use as a Possible Microbicide |
- HIV Infections
- Chlamydia Trachomatis
- Neisseria Gonorrhoeae
- (and 3 more...)
|
- Drug: Carraguard (PC-515)
|
Interventional |
Phase 2 |
- Population Council
- Bill and Melinda Gates Foundation
- Centers for Disease Control and Prevention
- (and 8 more...)
|
Other / U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double
- Primary Purpose: Other
|
- Safety: Genital exam & interview for symptoms after 14 days & monthly thereafter; colposcopy done throughout trial at clinicians' discretion; monthly testing to detect changes in vagina flora.
- Compliance: collection of applicators and interview(monthly)
- Acceptability: interview (quarterly)
- Preliminary effectiveness: Swabs taken to test for sexually transmitted infections - gonorrhea, chlamydia, trichomoniasis and for genital ulcer disease, if ulceration was detected; blood drawn for syphilis and HIV testing and for HSV-2 Pap smear to det
|
165 |
Female |
18 Years and older (Adult, Senior) |
NCT00213031 |
Population Council #271
CDC & Prevention #2485 |
|
February 2000 |
|
December 2001 |
September 21, 2005 |
August 14, 2017 |
|
- Chiang Rai Health Club
Chiang Rai, Thailand
|
| 27 |
NCT00248469 |
Completed |
MEMA Kwa Vijana Trial: Impact of an Adolescent Sexual and Reproductive Health Intervention in Mwanza, Tanzania |
- HIV Infections
- Sexually Transmitted Diseases
- Pregnancy
- Sexual Behavior
|
- Behavioral: In-school Sexual Health Education
- Behavioral: Youth-friendly health services
- Behavioral: Youth condom promotion & distribution
- Behavioral: Community activities related to adolescent sexual health
|
Interventional |
Phase 3 |
- London School of Hygiene and Tropical Medicine
- European Commission
- Development Cooperation Ireland (previously known as Ireland Aid)
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- HIV-1 seroincidence
- HSV2 seroprevalence
- Syphilis prevalence evaluated in each sex
- (and 14 more...)
|
10000 |
All |
14 Years and older (Child, Adult, Senior) |
NCT00248469 |
MkV1: ITIDRD90 |
|
July 1998 |
|
April 2002 |
November 4, 2005 |
October 20, 2006 |
|
- Tanzania National Institute for Medical Research
Mwanza, Tanzania
|
| 28 |
NCT00167505 |
Completed |
All About Youth: Evaluation of Sexual Risk Avoidance and Risk Reduction Programs for Middle School Students |
- Sexually Transmitted Diseases
- Pregnancy
- HIV Infections
|
- Behavioral: Risk Avoidance Intervention
- Behavioral: Risk Reduction Intervention
|
Interventional |
Not Applicable |
- The University of Texas Health Science Center, Houston
- Centers for Disease Control and Prevention
- Department of Health and Human Services
|
Other / U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- delay onset of sex
- knowledge
- skills
- (and 6 more...)
|
1742 |
All |
11 Years to 16 Years (Child) |
NCT00167505 |
U48DP000057 |
|
September 2006 |
July 2010 |
July 2010 |
September 14, 2005 |
October 26, 2010 |
|
- University of Texas Houston School of Public Health
Houston, Texas, United States
|
| 29 |
NCT00131235 |
Completed |
Gestational Sulfadoxine-pyrimethamine and Azithromycin Treatment to Prevent Preterm Birth |
- Malaria
- Sexually Transmitted Diseases
- Preterm Birth
- Pregnancy
|
- Drug: Sulfadoxine-pyrimethamine treatment twice during pregnancy
- Drug: Sulfadoxine-pyrimethamine at 4-week intervals
- Drug: Sulfadoxine-pyrimethamine every 4 weeks + azithromycin twice
|
Interventional |
Phase 3 |
- University of Tampere
- Academy of Finland
- Foundation for Paediatric Research, Finland
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Proportion of preterm births
- Number of serious and any adverse events
- Percentage of low birth weight babies
- (and 13 more...)
|
1320 |
Female |
15 Years and older (Child, Adult, Senior) |
NCT00131235 |
SA-179787-1 |
|
December 2003 |
May 2007 |
March 2012 |
August 17, 2005 |
January 22, 2014 |
|
- College of Medicine, University of Malawi
Mangochi, Mangochi District, Malawi
|
| 30 |
NCT01907126 |
Completed |
HIV/STI Risk Reduction for Incarcerated Women With Interpersonal Violence |
- Unsafe Sex
- Physical Violence
- Sexual Assault
- Sexual Abuse
|
- Behavioral: Nutrition Program (NP)
- Behavioral: Women's Prison CoOp (WPC)
|
Interventional |
Phase 2 |
- Brown University
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Number of Unprotected Sexual Occasions (USOs; Vaginal and Anal)
- Presence of Trichomoniasis
- Treatment Acceptability
- (and 5 more...)
|
42 |
Female |
18 Years and older (Adult, Senior) |
NCT01907126 |
R34MH094188 |
|
September 2011 |
October 2014 |
October 2014 |
July 24, 2013 |
January 13, 2016 |
|
- Massachusetts CorrectionalInstitution - Framingham
Framingham, Massachusetts, United States - South Middlesex CorrectionalCenter
Framingham, Massachusetts, United States - Adult Correctional Institution
Cranston, Rhode Island, United States
|
| 31 |
NCT00840658 |
Completed
Has Results |
Behavioral Intervention to Reduce Sexual and Injection Risks Among Female Sex Workers Who Also Inject Drugs in Mexico |
|
- Behavioral: Interactive injection and sexual risk intervention
- Behavioral: Interactive Sexual Risk Intervention
- Behavioral: Interactive Injection Risk Intervention
|
Interventional |
Phase 2 |
- Steffanie Strathdee
- National Institute on Drug Abuse (NIDA)
- University of California, San Diego
- (and 5 more...)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Prevention
|
- Combined HIV/STI 12-month Incidence Rates of HIV, Syphilis, Chlamydia, Gonorrhea and Trichomonas Vaginalis.
- Change (Baseline to 4-, 8-, and 12-months) in the a)Mean Number of Unprotected Sex Acts With Clients and b)Ratio of Unprotected Sex Acts With Clients (Relative to the Number of Sex Acts With Clients.
- Change (Baseline to 4-, 8-, and 12-months) in the a) Proportional Odds of Higher Receptive Needle Sharing and b) Mean Score of the Injection Risk Index (IRI).
|
584 |
Female |
18 Years and older (Adult, Senior) |
NCT00840658 |
DESPR R01DA023877
R01DA023877
5R01DA023877-02 |
FSW-IDU |
October 2008 |
July 2011 |
July 2011 |
February 10, 2009 |
December 24, 2014 |
September 18, 2012 |
- PrevenCasa, AC
Tijuana, Baja California, Mexico - Sadec-Femap
Ciudad Juarez, Chihuahua, Mexico
|
| 32 |
NCT01439503 |
Recruiting |
Safer Sex Program for Young African-American Men |
- Gonorrhea
- Chlamydia
- Trichomoniasis
- (and 2 more...)
|
|
Interventional |
Phase 2 |
- Richard Crosby
- National Institute of Mental Health (NIMH)
- University of Kentucky
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Prevention
|
- The frequency of unprotected sex rather than frequency of condom use will be used as the primary outcome measure.
|
620 |
Male |
15 Years to 29 Years (Child, Adult) |
NCT01439503 |
11-0204-F3R
1R01MH092226-01A1 |
|
September 2012 |
May 2018 |
May 2019 |
September 23, 2011 |
October 30, 2017 |
|
- Mississippi State Department of Health STD Clinic
Jackson, Mississippi, United States
|
| 33 |
NCT03090802 |
Recruiting |
MAMAS: Mentoring Adolescent Mothers at School |
- Human Immunodeficiency Virus
- Herpes Simplex Type II
- Chlamydia
- (and 2 more...)
|
- Behavioral: Mentoring Adolescent Mothers at School (MAMAS)
|
Interventional |
Not Applicable |
- Drexel University
- University of KwaZulu
- University of North Carolina, Chapel Hill
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Self-reported enrollment into school
- Self-report missed days in school in the past 30 days
- Self-reported number of men a participant has had sex with in the past 30 days
- (and 10 more...)
|
480 |
Female |
14 Years to 19 Years (Child, Adult) |
NCT03090802 |
1612005048
S-LMAQM-16-CA-1103 |
MAMAS |
June 26, 2017 |
September 30, 2018 |
September 30, 2018 |
March 27, 2017 |
December 18, 2017 |
|
- Philasende Clinic
Umlazi, South Africa
|
| 34 |
NCT01683461 |
Completed |
Efficacy of HIV Post-Test Support for ANC in South Africa |
- HIV
- Acquired Immunodeficiency Syndrome
|
- Behavioral: Enhanced Counseling
- Behavioral: Standard of Care
|
Interventional |
Not Applicable |
- University of North Carolina, Chapel Hill
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- University of KwaZulu
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Incidence of sexually transmitted disease
- Condom use
|
1500 |
Female |
18 Years and older (Adult, Senior) |
NCT01683461 |
07-1070
R01HD050134 |
SAHAPS |
May 2008 |
December 2011 |
December 2011 |
September 11, 2012 |
September 12, 2012 |
|
- University of KwaZulu-Natal
Durban, South Africa
|
| 35 |
NCT02513225 |
Recruiting |
Trial of an Adapted STD Screening and Risk Reduction Intervention |
- Alcohol Use
- Drug Use
- Diagnostic Self Evaluation
- (and 4 more...)
|
- Behavioral: Project EMPWR
- Other: Optimized Standard Care (OSC)
|
Interventional |
Not Applicable |
- Johns Hopkins Bloomberg School of Public Health
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
|
350 |
All |
18 Years to 49 Years (Adult) |
NCT02513225 |
14020838 |
|
July 2015 |
July 2018 |
July 2019 |
July 31, 2015 |
July 31, 2017 |
|
- Fort Apache Reservation
Fort Apache, Arizona, United States
|
| 36 |
NCT00121459 |
Withdrawn |
Effectiveness of the Diaphragm for HIV Prevention |
|
- Device: Ortho All-Flex diaphragm and Replens lubricant gel
|
Interventional |
Phase 3 |
- University of California, San Francisco
- Bill and Melinda Gates Foundation
- Ibis Reproductive Health
- (and 4 more...)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- HIV incidence
- STI incidence (CT, NG, syphilis, trichomoniasis, HSV2)
- acceptability
- feasibility and sustainability
|
0 |
Female |
18 Years to 49 Years (Adult) |
NCT00121459 |
H6070-22217-03
21082 |
|
September 2003 |
|
|
July 21, 2005 |
March 4, 2015 |
|
- Perinatal HIV Research Unit
Soweto, Gauteng, South Africa - Medical Research Council of South Africa
Durban, KwaZulu Natal, South Africa - UZ-UCSF
Harare, Zimbabwe
|
| 37 |
NCT00074425 |
Completed |
BufferGel and PRO 2000/5: Vaginal Gels to Prevent HIV Infection in Women |
|
- Drug: BufferGel
- Drug: PRO 2000/5 Gel
- Drug: Placebo gel
|
Interventional |
Phase 2 |
- National Institute of Allergy and Infectious Diseases (NIAID)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- National Institute on Drug Abuse (NIDA)
- (and 2 more...)
|
NIH / Other |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- Safety of BufferGel and 0.5% PRO 2000/5 Gel (P), as assessed by deep epithelial disruption, other genital symptoms, or other systemic symptoms
- HIV infection as measured by seroconversion
- Bacterial vaginosis
- (and 11 more...)
|
3101 |
Female |
18 Years and older (Adult, Senior) |
NCT00074425 |
HPTN 035
10065 |
|
January 2005 |
September 2008 |
September 2008 |
December 15, 2003 |
July 11, 2013 |
|
- 3535 Market Street CRS
Philadelphia, Pennsylvania, United States - University of North Carolina Lilongwe CRS
Lilongwe, Central, Malawi - College of Med. JHU CRS
Blantyre, Southern, Malawi - (and 5 more...)
|
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