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174 studies found for:    treatment experienced OR treatment failure OR second line OR resistance OR salvage therapy | Open Studies | HIV
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treatment experienced OR treatment failure OR second line OR resistance OR salvage therapy | Open Studies | HIV (174 records)
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Rank Status Study
1 Recruiting Resistance in HIV+ in North and South
Condition: HIV Drug Resistance
Intervention:
2 Recruiting Ibalizumab Plus Optimized Background Regimen in Treatment-Experienced Patients With Multi-Drug Resistant HIV-1
Condition: HIV
Interventions: Drug: ibalizumab;   Drug: Optimized Background Regimen
3 Recruiting A Randomized, Double-blind, Placebo-controlled Trial, Followed by Single-arm Treatment of PRO 140 in Combination w/ Optimized Background Therapy in Treatment-Experienced HIV Subjects
Condition: HIV
Interventions: Drug: PRO 140;   Drug: Placebo;   Drug: Optimized Background Regimen
4 Recruiting Pharmacokinetics, Safety, and Efficacy of Cobicistat-boosted Atazanavir or Cobicistat-boosted Darunavir in HIV-1 Infected, Treatment-Experienced, Virologically Suppressed Pediatric Subjects
Conditions: Acquired Immune Deficiency Syndrome (AIDS);   HIV Infections
Interventions: Drug: ATV;   Drug: DRV;   Drug: Cobicistat;   Drug: BR
5 Recruiting Evaluating the Safety and Tolerability of Etravirine in HIV-1 Infected Infants and Children
Condition: HIV Infections
Intervention: Drug: Etravirine (ETR)
6 Recruiting Strategy-confirming Study of BMS-955176 to Treat HIV-1 Infected Treatment-experienced Adults
Condition: HIV/AIDS
Interventions: Drug: BMS-955176;   Drug: Atazanavir(ATV);   Drug: Ritonavir(RTV);   Drug: Dolutegravir(DTG);   Drug: Tenofovir(TDF)
7 Recruiting Attachment Inhibitor Comparison in Heavily Treatment Experienced Patients
Condition: HIV/AIDS
Interventions: Drug: BMS-663068;   Other: Placebo
8 Recruiting Safety and Efficacy of MK-1439A in Participants Infected With Treatment-Naïve Human Immunodeficiency Virus (HIV) -1 With Transmitted Resistance (MK-1439A-030)
Condition: HIV-1 Infection
Intervention: Drug: MK-1439A
9 Recruiting Resistance Testing to Improve Management of Virologic Failure in Sub-Saharan Africa
Conditions: HIV;   AIDS
Intervention: Procedure: HIV-1 RNA Resistance Testing
10 Recruiting Switching to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Fixed Dose Combination (FDC) in Virologically-Suppressed HIV-1 Infected Adults Harboring the Archived Isolated NRTI Resistance Mutation M184V/M184I
Condition: HIV-1 Infection
Intervention: Drug: E/C/F/TAF
11 Not yet recruiting Evaluating the Pharmacokinetics, Safety, and Tolerability of Bedaquiline in HIV-Infected and HIV-Uninfected Infants, Children, and Adolescents With Multidrug-Resistant Tuberculosis
Conditions: Tuberculosis;   HIV Infections
Intervention: Drug: Bedaquiline
12 Recruiting Seroconversions, Resistance, Adverse Events and Drug Adherence Among Subjects Taking Truvada® for PrEP: A Case Control Study
Condition: HIV
Intervention:
13 Recruiting Dolutegravir Expanded Access Study
Condition: Infection, Human Immunodeficiency Virus
Intervention: Drug: Dolutegravir
14 Recruiting Efficacy and Safety of a Dolutegravir-based Regimen for the Initial Management of HIV Infected Adults in Resource-limited Settings
Condition: HIV-1 Infection
Interventions: Drug: Dolutegravir 50 mg;   Drug: Tenofovir disoproxil fumarate 300 mg / lamivudine 300 mg;   Drug: Efavirenz 200 mg
15 Recruiting Targeted Clinical Strategies and Low Level Viraemia (LLV) in Boosted Protease Inhibitor Therapy
Condition: HIV
Intervention:
16 Recruiting International HIV Antiretroviral Adherence, Resistance and Survival
Condition: HIV/AIDS
Intervention:
17 Not yet recruiting A Randomised Trial of Dolutegravir (DTG)-Based Antiretroviral Therapy vs. Standard of Care (SOC) in Children With HIV Infection Starting First-line or Switching to Second-line ART
Condition: HIV Infection
Intervention: Drug: DTG
18 Recruiting HIV-DNA Dynamics in HIV Monoinfected or HIV/HCV Coinfected Patients
Condition: HIV
Intervention: Procedure: Blood sample withdrawal
19 Recruiting HIV-Resistant Gene Modified Stem Cells and Chemotherapy in Treating Patients With Lymphoma With HIV Infection
Conditions: HIV Infection;   Stage I Adult Hodgkin Lymphoma;   Stage I Adult Non-Hodgkin Lymphoma;   Stage II Adult Hodgkin Lymphoma;   Stage II Adult Non-Hodgkin Lymphoma;   Stage III Adult Hodgkin Lymphoma;   Stage III Adult Non-Hodgkin Lymphoma;   Stage IV Adult Hodgkin Lymphoma;   Stage IV Adult Non-Hodgkin Lymphoma
Interventions: Biological: C46/CCR5/P140K Lentiviral Vector-transduced Autologous HSPCs;   Drug: Carmustine;   Biological: Filgrastim;   Other: Laboratory Biomarker Analysis;   Drug: O6-Benzylguanine;   Drug: Plerixafor
20 Not yet recruiting Improving Outcomes With Metformin
Conditions: HIV Infection;   Hepatitis C
Interventions: Drug: Metformin;   Other: No treatment

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Study has passed its completion date and status has not been verified in more than two years.