96 studies found for:    topeka | Open Studies
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Rank Status Study
21 Recruiting Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic
Conditions: Estrogen Receptor Positive;   HER2/Neu Negative;   Male Breast Carcinoma;   Progesterone Receptor Positive;   Recurrent Breast Carcinoma;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer;   Stage IV Breast Cancer
Interventions: Drug: Entinostat;   Drug: Exemestane;   Drug: Goserelin Acetate;   Other: Laboratory Biomarker Analysis;   Other: Placebo;   Other: Quality-of-Life Assessment
22 Recruiting Enzalutamide With or Without Abiraterone and Prednisone in Treating Patients With Castration-Resistant Metastatic Prostate Cancer
Conditions: Adenocarcinoma of the Prostate;   Hormone-resistant Prostate Cancer;   Recurrent Prostate Cancer;   Stage IV Prostate Cancer
Interventions: Drug: enzalutamide;   Drug: abiraterone;   Drug: prednisone
23 Recruiting Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease
Condition: Diabetic Kidney Disease
Interventions: Drug: Finerenone (BAY94-8862);   Drug: Placebo
24 Recruiting Safety Study in Patients With Multiple Sclerosis Treated Fingolimod or Other Approved Disease-modifying Therapies
Condition: Multiple Sclerosis
Interventions: Drug: Fingolimod;   Drug: other disease-modifying therapy
25 Recruiting Olaparib as Adjuvant Treatment in Patients With Germline BRCA Mutated High Risk HER2 Negative Primary Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Olaparib;   Drug: Placebo
26 Recruiting Efficacy and Safety of Oral Semaglutide Versus Liraglutide and Versus Placebo in Subjects With Type 2 Diabetes Mellitus
Conditions: Diabetes;   Diabetes Mellitus, Type 2
Interventions: Drug: semaglutide;   Drug: liraglutide;   Drug: placebo
27 Recruiting A Study to Investigate the Safety and Efficacy of LT-02 in Patients With Mesalamine Refractory Ulcerative Colitis (UC)
Condition: Ulcerative Colitis
Interventions: Drug: LT-02;   Drug: LT-02 Placebo
28 Recruiting Efficacy of Near Infrared Phototherapy in Type 2 Diabetic Neuropathy
Condition: Neuropathy
Interventions: Other: Infrared Phototherapy;   Other: Sham
29 Recruiting A Study of LY3202626 on Disease Progression in Participants With Mild Alzheimer's Disease Dementia
Condition: Alzheimer's Disease
Interventions: Drug: LY3202626;   Drug: Placebo
30 Recruiting Study in Patients With Unresectable And Metastatic Melanoma: The Optimize Study
Condition: Melanoma
Intervention:
31 Recruiting A Study of Solanezumab (LY2062430) in Participants With Prodromal Alzheimer's Disease
Condition: Alzheimer's Disease
Interventions: Drug: Solanezumab;   Drug: Placebo
32 Recruiting Long Term Safety Study of Plecanatide
Condition: Irritable Bowel Syndrome
Intervention: Drug: Plecanatide
33 Recruiting Safety and Efficacy Study of Albiglutide Liquid Drug Product in Type 2 Diabetes Mellitus
Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Lyophilized albiglutide DCC pen injector;   Drug: Lyophilized albiglutide DCC pen injector matching placebo;   Drug: Albiglutide liquid auto-injector;   Drug: Albiglutide liquid auto-injector matching placebo
34 Recruiting 12-Week Study of DS-8500a in Subjects With Type 2 Diabetes Mellitus on Metformin
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: Sitagliptin 100 mg;   Drug: DS-8500a 25mg;   Drug: placebo
35 Recruiting Study of the Safety and Tolerability of Switching to ITCA 650 in Patients With Type 2 Diabetes Receiving Liraglutide
Condition: Diabetes Mellitus, Type 2
Interventions: Drug: ITCA 650 20/60 mcg/day;   Drug: ITCA 650 60 mcg/day
36 Recruiting Avelumab in Third-Line Gastric Cancer (JAVELIN Gastric 300)
Conditions: Unresectable, Recurrent, Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma;   Gastric Cancer Third Line
Interventions: Drug: Avelumab;   Drug: Irinotecan;   Drug: Paclitaxel;   Other: Best Supportive Care (BSC)
37 Recruiting Avelumab in First-Line Gastric Cancer (JAVELIN Gastric 100)
Condition: Unresectable, Locally Advanced or Metastatic, Adenocarcinoma of the Stomach, or of the Gastro Esophageal Junction
Interventions: Drug: Avelumab;   Drug: Oxaliplatin;   Drug: 5-Fluorouracil;   Drug: Leucovorin;   Drug: Capecitabine;   Other: Best supportive care
38 Recruiting A 12-Week Study With a 4-Week Randomized Withdrawal Period to Evaluate the Efficacy and Safety of Tenapanor for the Treatment of IBS-C
Condition: Constipation Predominant Irritable Bowel Syndrome
Interventions: Drug: Tenapanor;   Drug: Placebo
39 Recruiting Vedolizumab Subcutaneous Long-Term Open-Label Extension Study
Conditions: Colitis, Ulcerative;   Crohn Disease
Intervention: Drug: Vedolizumab SC
40 Recruiting Efficacy and Safety of Vedolizumab Subcutaneously (SC) as Maintenance Therapy in Ulcerative Colitis
Condition: Colitis, Ulcerative
Interventions: Drug: Vedolizumab IV 300 mg;   Drug: Placebo IV;   Drug: Vedolizumab SC 108 mg;   Drug: Placebo SC

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