47 studies found for:    symplicity
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Rank Status Study
1 Active, not recruiting Renal Denervation in Patients With Uncontrolled Hypertension - SYMPLICITY HTN-4
Conditions: Hypertension;   Vascular Diseases;   Cardiovascular Diseases
Interventions: Device: Renal Denervation;   Other: Sham Renal Denervation;   Device: Renal Angiography
2 Active, not recruiting Renal Denervation in Patients With Uncontrolled Hypertension (SYMPLICITY HTN-3)
Condition: Uncontrolled Hypertension
Interventions: Device: Renal denervation (Symplicity Catheter System);   Other: Renal angiogram;   Drug: Maintained base-line anti-hypertensive medications
3 Not yet recruiting Renal Denervation in Patients With Chronic Heart Failure
Conditions: Chronic Heart Failure;   Cardio-Renal Syndrome
Intervention: Device: Renal denervation (Symplicity™)
4 Terminated Single-arm Study of Symplicity™ Renal Denervation System in Patients With Uncontrolled HyperTensioN in India
Condition: Adults With Uncontrolled Hypertension
Intervention: Device: Symplicity renal denervation system
5 Completed
Has Results
Renal Denervation in Patients With Uncontrolled Hypertension (Symplicity HTN-2)
Condition: Uncontrolled Hypertension
Intervention: Device: Renal Denervation (Symplicity® Renal Denervation System)
6 Recruiting Renal Nerve Denervation in Patients With Hypertension and Paroxysmal and Persistent Atrial Fibrillation
Conditions: Atrial Fibrillation;   Hypertension
Interventions: Drug: Renal nerve denervation;   Device: Cryoablation
7 Recruiting SPYRAL HTN-ON MED Study
Conditions: Hypertension;   Vascular Diseases;   Cardiovascular Diseases
Interventions: Device: Symplicity Spyral™ multi-electrode renal denervation system;   Procedure: Sham Procedure
8 Recruiting SPYRAL HTN-OFF MED Study
Conditions: Hypertension;   Vascular Diseases;   Cardiovascular Diseases
Interventions: Device: Symplicity Spyral™ multi-electrode renal denervation system;   Procedure: Sham Procedure
9 Terminated
Has Results
Study of Renal Denervation in Patients With Heart Failure
Condition: Heart Failure
Intervention: Device: Symplicity Renal Denervation
10 Recruiting Global SYMPLICITY Registry
Conditions: Hypertension;   Diabetes Mellitus;   Heart Failure;   Chronic Kidney Disease;   Sleep Apnea
Intervention: Device: Medtronic Renal Denervation System
11 Unknown  Renal Denervation for Treatment of Resistant Hypertension in Patients With Chronic Kidney Disease
Conditions: Hypertension;   Chronic Kidney Disease
Intervention: Procedure: Renal denervation
12 Recruiting Renal Sympathetic Denervation Prevents Atrial Fibrillation in Patients With Hypertensive Heart Disease: a Pilot Study
Conditions: Hypertension;   Hypertensive Heart Disease;   Atrial Fibrillation;   Autonomic Imbalance
Interventions: Device: Renal denervation;   Drug: Medical therapy
13 Recruiting Renal Denervation in Treatment Resistant Hypertension
Condition: Hypertension
Intervention: Device: Renal denervation using Symplicity Catheter system
14 Active, not recruiting Renal Denervation in Patients With Resistant Hypertension and Obstructive Sleep Apnea
Conditions: Hypertension;   Obstructive Sleep Apnea
Intervention: Device: Renal denervation with a catheter-based procedure (Symplicity® Catheter System)
15 Recruiting Influence of Catheter-based Renal Denervation in Diseases With Increased Sympathetic Activity
Conditions: Hypertension;   Heart Failure;   Chronic Kidney Disease;   Diabetes;   Heart Rhythm Disorders
Interventions: Device: Renal denervation with Symplicity Flex Medtronic/Ardian;   Device: Renal denervation with EnligHTN St. Jude Medical;   Device: Renal denervation with Paradise Recor;   Device: Renal denervation with V2 Vessix
16 Active, not recruiting Prairie Renal Denervation Study
Condition: Chronic Kidney Disease
Intervention: Procedure: Symplicity Renal Denervation System
17 Terminated A Study of Renal Denervation in Patients With Treatment Resistant Hypertension
Condition: Treatment-Resistant Hypertension
Intervention: Device: Renal denervation device
18 Completed Renal Denervation in Patients With Refractory Hypertension
Condition: Hypertension
Intervention: Device: Ardian Symplicity™ Catheter
19 Completed Renal Sympathetic Denervation and Potential Effects on Glucose Metabolism and Cardiovascular Risk-Factors
Condition: Hypertension, Resistant to Conventional Therapy
Intervention: Procedure: Renal sympathetic denervation
20 Completed Impact of Sympathetic Renal Denervation- a Study in Patients After Renal Transplantation
Conditions: Hypertension;   Chronic Kidney Disease;   Renal Transplantation;   Sympathetic Activity
Intervention: Device: Catheter-based renal denervation

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Indicates status has not been verified in more than two years