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63 studies found for:    spironolactone | Open Studies
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Rank Status Study
1 Recruiting Effect of Spironolactone on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess
Conditions: Obesity;   Hyperandrogenemia;   Polycystic Ovary Syndrome
Intervention: Drug: Spironolactone
2 Recruiting The Combination Ambrisentan Plus Spironolactone in Pulmonary Arterial Hypertension Study
Condition: Pulmonary Arterial Hypertension
Interventions: Drug: Ambrisentan plus Spironolactone;   Drug: Ambrisentan plus Placebo
3 Recruiting Spironolactone Administration to Prevent Ischemic Kidney Injury in Critically Ill Cancer Patients
Conditions: Critically Ill;   Cancer
Interventions: Drug: Spironolactone;   Drug: Placebo
4 Recruiting Spironolactone After Liver Transplant
Condition: Transplant, Liver
Intervention: Drug: Spironolactone
5 Recruiting Determining the Effect of Spironolactone on Electrolyte Supplementation in Preterm Infants With Chronic Lung Disease
Conditions: Chronic Lung Disease;   Bronchopulmonary Dysplasia
Interventions: Drug: Spironolactone;   Drug: Placebo
6 Not yet recruiting Evaluating the Effect of Spironolactone on Hypertrophic Cardiomyopathy
Conditions: Hypertrophic Cardiomyopathy;   Fibrosis
Intervention: Drug: Spironolactone
7 Not yet recruiting Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction
Condition: Heart Failure With Preserved Ejection Fraction
Interventions: Drug: Spironolactone;   Other: Standard care
8 Recruiting Spironolactone With Patiromer in the Treatment of Resistant Hypertension in Chronic Kidney Disease
Conditions: Hyperkalemia;   Resistant Hypertension
Interventions: Drug: Patiromer;   Drug: Placebo;   Drug: Spironolactone
9 Recruiting Comparing the Effects of Spironolactone With Chlortalidone on LV Mass in Patients With CKD
Conditions: Renal Insufficiency, Chronic;   Cardio-Renal Syndrome
Interventions: Drug: Spironolactone;   Drug: Chlortalidone
10 Recruiting Mineralocorticoid Receptor Antagonism Clinical Evaluation in Atherosclerosis Trial
Condition: Atherosclerosis
Interventions: Drug: Spironolactone;   Drug: Placebo
11 Recruiting Acetazolamide and Spironolactone to Increase Natriuresis in Congestive Heart Failure
Condition: Heart Failure
Interventions: Drug: Combination therapy with acetazolamide and low-dose loop diuretics;   Drug: High-dose loop diuretics;   Drug: Upfront therapy with oral spironolactone
12 Not yet recruiting Spironolactone on Fibrosis Progrssion-Portal Hypertension(FP-PH)in Cirrhosis
Conditions: Cirrhosis;   Portal Hypertension
Interventions: Drug: Spironolactone;   Drug: Carvedilol
13 Not yet recruiting Colchicine and Spironolactone in Patients With STEMI / SYNERGY Stent Registry
Condition: ST Elevation Myocardial Infarction
Interventions: Drug: Colchicine;   Drug: Spironolactone;   Device: SYNERGY Bioabsorbable Polymer Drug-Eluting Stent;   Drug: Colchicine-Placebo;   Drug: Spironolactone-Placebo
14 Recruiting Spironolactone for Pulmonary Arterial Hypertension
Condition: Pulmonary Arterial Hypertension
Interventions: Drug: Spironolactone;   Drug: Placebo
15 Recruiting High-dose Aldosterone Antagonist for Acute Decompensated Heart Failure
Condition: Acute Decompensated Heart Failure
Intervention: Drug: Spironolactone and patiromer
16 Recruiting Therapeutic Potential for Aldosterone Inhibition in Duchenne Muscular Dystrophy
Condition: Duchenne Muscular Dystrophy
Interventions: Drug: Eplerenone;   Drug: Spironolactone
17 Recruiting Mineralocorticoid Receptor Antagonists (MRA) in Heart Failure (HF) and Loop Diuretic Resistance
Condition: Heart Failure
Interventions: Drug: Spironolactone 100mg;   Drug: Spironolactone 25mg
18 Recruiting ALdosterone Antagonist Chronic HEModialysis Interventional Survival Trial
Condition: End Stage Renal Failure on Dialysis
Interventions: Drug: Spironolactone;   Drug: Placebo
19 Recruiting Hyperandrogenemia and Altered Day-night LH Pulse Patterns
Condition: Polycystic Ovary Syndrome
Interventions: Drug: Spironolactone;   Drug: Placebo;   Drug: Micronized progesterone solution
20 Not yet recruiting Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease
Condition: Endstage Renal Disease
Interventions: Drug: Spironolactone 25Mg Tablet;   Drug: Placebo Oral Tablet

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Study has passed its completion date and status has not been verified in more than two years.