56 studies found for:    spironolactone | Open Studies
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Rank Status Study
1 Recruiting Effects of Spironolactone on Collagen Metabolism in Patients With Pulmonary Arterial Hypertension
Condition: Pulmonary Hypertension
Interventions: Drug: Spironolactone;   Drug: Placebo
2 Recruiting Effect of Spironolactone on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess
Conditions: Obesity;   Hyperandrogenemia;   Polycystic Ovary Syndrome
Intervention: Drug: Spironolactone
3 Recruiting The Combination Ambrisentan Plus Spironolactone in Pulmonary Arterial Hypertension Study
Condition: Pulmonary Arterial Hypertension
Interventions: Drug: Ambrisentan plus Spironolactone;   Drug: Ambrisentan plus Placebo
4 Recruiting Spironolactone Administration to Prevent Ischemic Kidney Injury in Critically Ill Cancer Patients
Conditions: Critically Ill;   Cancer
Interventions: Drug: Spironolactone;   Drug: Placebo
5 Recruiting Spironolactone After Liver Transplant
Condition: Transplant, Liver
Intervention: Drug: Spironolactone
6 Recruiting Determining the Effect of Spironolactone on Electrolyte Supplementation in Preterm Infants With Chronic Lung Disease
Conditions: Chronic Lung Disease;   Bronchopulmonary Dysplasia
Interventions: Drug: Spironolactone;   Drug: Placebo
7 Not yet recruiting Evaluating the Effect of Spironolactone on Hypertrophic Cardiomyopathy
Conditions: Hypertrophic Cardiomyopathy;   Fibrosis
Intervention: Drug: Spironolactone
8 Recruiting Comparing the Effects of Spironolactone With Chlortalidone on LV Mass in Patients With CKD
Conditions: Renal Insufficiency, Chronic;   Cardio-Renal Syndrome
Interventions: Drug: Spironolactone;   Drug: Chlortalidone
9 Not yet recruiting Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction
Condition: Heart Failure With Preserved Ejection Fraction
Interventions: Drug: Spironolactone;   Other: Standard care
10 Recruiting Acetazolamide and Spironolactone to Increase Natriuresis in Congestive Heart Failure
Condition: Heart Failure
Interventions: Drug: Combination therapy with acetazolamide and low-dose loop diuretics;   Drug: High-dose loop diuretics;   Drug: Upfront therapy with oral spironolactone
11 Not yet recruiting Spironolactone on Fibrosis Progrssion-Portal Hypertension(FP-PH)in Cirrhosis
Conditions: Cirrhosis;   Portal Hypertension
Interventions: Drug: Spironolactone;   Drug: Carvedilol
12 Recruiting Spironolactone for Pulmonary Arterial Hypertension
Condition: Pulmonary Arterial Hypertension
Interventions: Drug: Spironolactone;   Drug: Placebo
13 Recruiting High-dose Aldosterone Antagonist for Acute Decompensated Heart Failure
Condition: Acute Decompensated Heart Failure
Intervention: Drug: Spironolactone and patiromer
14 Recruiting Therapeutic Potential for Aldosterone Inhibition in Duchenne Muscular Dystrophy
Condition: Duchenne Muscular Dystrophy
Interventions: Drug: Eplerenone;   Drug: Spironolactone
15 Recruiting Mineralocorticoid Receptor Antagonists (MRA) in Heart Failure (HF) and Loop Diuretic Resistance
Condition: Heart Failure
Interventions: Drug: Spironolactone 100mg;   Drug: Spironolactone 25mg
16 Recruiting ALdosterone Antagonist Chronic HEModialysis Interventional Survival Trial
Condition: End Stage Renal Failure on Dialysis
Interventions: Drug: Spironolactone;   Drug: Placebo
17 Not yet recruiting Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease
Condition: Endstage Renal Disease
Interventions: Drug: Spironolactone 25Mg Tablet;   Drug: Placebo Oral Tablet
18 Recruiting Evaluation of the Efficacy of Diuretics for Symptomatic Malignant Ascites Episodes in Advanced Stage of Cancer (DIASC)
Condition: Cancer
Intervention: Drug: Spironolactone (+/- Furosemide)
19 Recruiting Vascular Effects of Mineralocorticoid Receptor Antagonism in Kidney Disease
Conditions: Chronic Kidney Disease;   Albuminuria
Interventions: Drug: Spironolactone;   Drug: Amiloride
20 Recruiting Biomarker Guided Therapies in Stage A/B Heart Failure
Conditions: Hypertension;   Diabetes;   Cardiovascular Disease
Interventions: Drug: Carvedilol;   Drug: Spironolactone

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Study has passed its completion date and status has not been verified in more than two years.