Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
51 studies found for:    spironolactone | Open Studies
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Rank Status Study
1 Not yet recruiting The Combination Ambrisentan Plus Spironolactone in Pulmonary Arterial Hypertension Study
Condition: Pulmonary Arterial Hypertension
Interventions: Drug: Ambrisentan plus Spironolactone;   Drug: Ambrisentan plus Placebo
2 Recruiting Effects of Spironolactone on Collagen Metabolism in Patients With Pulmonary Arterial Hypertension
Condition: Pulmonary Hypertension
Interventions: Drug: Spironolactone;   Drug: Placebo
3 Recruiting Acetazolamide and Spironolactone to Increase Natriuresis in Congestive Heart Failure
Condition: Heart Failure
Interventions: Drug: Combination therapy with acetazolamide and low-dose loop diuretics;   Drug: High-dose loop diuretics;   Drug: Upfront therapy with oral spironolactone
4 Unknown  Effects of Spironolactone in Dialysis
Condition: Renal Failure
Intervention: Drug: Spironolactone
5 Recruiting Determining the Effect of Spironolactone on Electrolyte Supplementation in Preterm Infants With Chronic Lung Disease
Conditions: Chronic Lung Disease;   Bronchopulmonary Dysplasia
Interventions: Drug: Spironolactone;   Drug: Placebo
6 Unknown  Spironolactone for Paroxysmal Atrial Fibrillation
Condition: Atrial Fibrillation
Interventions: Drug: Spironolactone;   Drug: Placebo
7 Unknown  Effect of Spironolactone on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess
Conditions: Obesity;   Hyperandrogenemia;   Polycystic Ovary Syndrome
Interventions: Drug: Spironolactone;   Drug: Dexamethasone;   Drug: Cosyntropin;   Drug: r-hCG (Ovidrel)
8 Recruiting The Effect of Spironolactone on Pain in Older People With Osteoarthritis
Condition: Osteoarthritis, Knee
Intervention: Drug: spironolactone
9 Recruiting Study of High-dose Spironolactone vs. Placebo Therapy in Acute Heart Failure
Condition: Heart Failure
Interventions: Drug: Spironolactone;   Drug: Placebo
10 Unknown  Effect of Spironolactone in Treating Chronic Non-resolutive Central Serous Chorioretinitis
Condition: Central Serous Chorioretinitis
Interventions: Drug: Spironolactone;   Drug: Placebo
11 Unknown  Addition of Spironolactone in Patients With Resistant Arterial Hypertension
Condition: Hypertension
Intervention: Drug: spironolactone
12 Not yet recruiting Safety and Cardiovascular Efficacy of Spironolactone in Dialysis-Dependent ESRD Trial
Condition: End-Stage Renal Disease
Intervention: Drug: Spironolactone
13 Recruiting Comparison of Effects of Eplerenone Versus Spironolactone in Heart Failure Patients With Glucose Intolerance or Type 2 Diabetes
Conditions: Heart Failure;   Type 2 Diabetes;   Glucose Intolerance
Interventions: Drug: Eplerenone;   Drug: Spironolactone
14 Unknown  Efficacy of Therapy With the Spironolactone Pills Compared to Minoxidil Lotion in Female Pattern Hair Loss
Condition: Female Pattern Hair Loss
Interventions: Drug: Spironolactone;   Drug: Minoxidil
15 Recruiting Mineralocorticoid Receptor Antagonists in End Stage Renal Disease
Condition: End Stage Renal Disease / Hemodialysis
Intervention: Drug: Spironolactone
16 Recruiting ALdosterone Antagonist Chronic HEModialysis Interventional Survival Trial
Condition: End Stage Renal Failure on Dialysis
Interventions: Drug: Spironolactone;   Drug: Placebo
17 Recruiting Therapeutic Potential for Aldosterone Inhibition in Duchenne Muscular Dystrophy
Condition: Duchenne Muscular Dystrophy
Interventions: Drug: Eplerenone;   Drug: Spironolactone
18 Recruiting Spironolactone for Pulmonary Arterial Hypertension
Condition: Pulmonary Arterial Hypertension
Interventions: Drug: Spironolactone;   Drug: Placebo
19 Unknown  Cardiovascular Protective Effect of Spironolactone in Hemodialysis
Condition: Hemodialysis
Intervention: Drug: Spironolactone (drug)
20 Recruiting Proteomic Prediction and Renin Angiotensin Aldosterone System Inhibition Prevention Of Early Diabetic nephRopathy In TYpe 2 Diabetic Patients With Normoalbuminuria
Conditions: Diabetic Nephropathy;   Diabetic Retinopathy
Interventions: Drug: Spironolactone;   Drug: Placebo;   Drug: Standard care

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Indicates status has not been verified in more than two years