64 studies found for:    spinal muscular atrophy | "Spinal muscular atrophy"
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Rank Status Study
1 Terminated
Has Results
Clinical Trial of Sodium Phenylbutyrate in Children With Spinal Muscular Atrophy Types II or III
Conditions: Spinal Muscular Atrophy Type II;   Spinal Muscular Atrophy Type III
Intervention: Drug: sodium phenylbutyrate
2 Terminated
Has Results
Clinical Trial of Sodium Phenylbutyrate in Children With Spinal Muscular Atrophy Type I
Condition: Spinal Muscular Atrophy Type I
Intervention: Drug: sodium phenylbutyrate
3 Completed CARNIVAL Type I: Valproic Acid and Carnitine in Infants With Spinal Muscular Atrophy (SMA) Type I
Condition: Spinal Muscular Atrophy Type I
Intervention: Drug: Valproic Acid and Levocarnitine
4 Completed Clinical Assessment of Spinal Muscular Atrophy Type II and III (SMA Europe)
Condition: Spinal Muscular Atrophy
Intervention: Other: Functional tests
5 Not yet recruiting Prospective Study of the Natural History of Patients With Type 2 and 3 Spinal Muscular Atrophy
Conditions: Type 2 Spinal Muscular Atrophy;   Type 3 Spinal Muscular Atrophy
Interventions: Other: Strength, function and activity measurements;   Other: Muscle MRI;   Other: Electrophysiology measurements;   Other: Blood sampling for biomarker analysis
6 Recruiting Pilot Study of an Innovative Physiotherapy in Patients With Infantile Spinal Muscular Atrophy (SMA)
Condition: Infantile Spinal Muscular Atrophy of Type 2 or 3
Intervention: Other: Physical exercise in a swimming pool during 6 months
7 Completed A Pilot Study of Biomarkers for Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention:
8 Active, not recruiting Spinal Muscular Atrophy (SMA) Biomarkers Study in the Immediate Postnatal Period of Development
Condition: Spinal Muscular Atrophy (SMA)
Intervention:
9 Completed Spinal Muscular Atrophy and Cardiac Autonomic Function
Condition: Spinal Muscular Atrophy
Intervention: Procedure: Air stacking manuever
10 Active, not recruiting Newborn Screening for Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention: Other: newborn screening test for SMA
11 Enrolling by invitation Mechanisms of Cell Death in Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention:
12 Unknown  Infants With Spinal Muscular Atrophy Type I
Condition: Spinal Muscular Atrophy
Intervention:
13 Completed
Has Results
Valproic Acid and Carnitine in Patients With Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Interventions: Drug: Valproic Acid and Levocarnitine;   Drug: Placebo
14 Completed Valproic Acid in Ambulant Adults With Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Interventions: Drug: Valproic Acid (VPA);   Drug: Placebo
15 Active, not recruiting Clinical Trial of Exercise in Patients With Spinal Muscular Atrophy (SMA)
Conditions: Spinal Muscular Atrophy;   Neuromuscular Disease
Intervention: Other: Exercise
16 Completed Study to Evaluate Sodium Phenylbutyrate in Pre-symptomatic Infants With Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention: Drug: Sodium phenylbutyrate (NaPB)
17 Recruiting A Study to Assess the Efficacy and Safety of ISIS-SMN Rx in Infants With Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Interventions: Drug: ISIS-SMN Rx;   Procedure: Sham procedure
18 Active, not recruiting A Study to Assess the Safety and Pharmacokinetics of ISIS SMNRx in Infants With Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention: Drug: ISIS-SMNRx
19 Recruiting A Study to Assess the Efficacy and Safety of ISIS-SMN Rx in Patients With Later-onset Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Interventions: Drug: ISIS-SMN Rx;   Procedure: Sham procedure
20 Completed An Open-label Safety, Tolerability, and Dose-range Finding Study of ISIS SMNRx in Patients With Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention: Drug: ISIS-SMNRx

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Indicates status has not been verified in more than two years