54 studies found for:    sickle cell anemia OR sickle cell disease OR hemoglobin S disease OR hemoglobin SS disease | Open Studies | NIH, U.S. Fed
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Rank Status Study
1 Recruiting Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure
Conditions: Sickle Cell Disease;   Thalassemia;   Stem Cell Transplantation;   Graft vs Host Disease
Interventions: Drug: Alemtuzumab;   Drug: Sirolimus;   Drug: Cyclophosphamide;   Drug: Pentostatin;   Drug: Radiotherapy
2 Recruiting Blood Flow and Pain Crises in People With Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention:
3 Recruiting Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
Conditions: Pulmonary Hypertension;   Sickle Cell Anemia;   Sickle Cell Disease
Intervention:
4 Recruiting Collection and Storage of Umbilical Cord Stem Cells for Treatment of Sickle Cell Disease
Conditions: Sickle Cell Disease;   Sickle Cell Trait
Intervention:
5 Recruiting Genetics and Pain Severity in Sickle Cell Disease
Conditions: Genotype;   Pain;   Sickle Cell Anemia;   Vaso-Occlusive Pain Crisis
Intervention:
6 Recruiting Bone Marrow Transplantation in Young Adults With Severe Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention: Other: Biological: Bone Marrow Transplant
7 Recruiting Natural History of Sickle Cell Disease and Other Hemolytic Disorders
Conditions: Hemoglobin SC Disease;   Hematologic Diseases;   Sickle Cell Anemia;   Hemolytic Anemia
Intervention:
8 Recruiting Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients With Blood Disorders
Conditions: Sickle Cell Anemia;   Sickle Cell Disease;   Chronic Hemolytic Disorders
Intervention: Drug: Sodium Nitrite Cream
9 Not yet recruiting Comparing Acute Pain Management Protocols for Patients With Sickle Cell Disease
Condition: Sickle Cell Disease
Interventions: Drug: Hydromorphone (Standardized, weight-based dosing);   Drug: Morphine Sulfate (Standardized, weight-based dosing);   Drug: Hydromorphone (Patient Specific dosing);   Drug: Morphine Sulfate (Patient Specific dosing)
10 Recruiting Assessment of Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Function in People With Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention: Drug: Hydroxyurea
11 Recruiting The Link Between Anemia and Deficits in Memory and Attention in Individuals With Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention:
12 Recruiting Insights Into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers Study (INSIGHTS Study)
Conditions: Genetic Disease;   Genomics
Intervention:
13 Recruiting Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease and Beta-Thalassemia
Conditions: Peripheral Blood Stem Cell Transplantation;   Anemia, Sickle Cell;   Graft-Versus-Host Disease;   Sirolimus (Rapamune );   Alemtuzumab (Campath )
Interventions: Procedure: PBMC Transplant;   Drug: Alemtuzumab (Campath  );   Drug: Sirolimus (Rapamune  );   Drug: Cyclophosphamide (Cytoxan  );   Procedure: Low Dose Irradiation
14 Recruiting Evaluation of Sickle Cell Liver Disease
Condition: Sickle Cell Disease
Intervention:
15 Recruiting Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias
Conditions: Congenital Hemolytic Anemia;   Diamond-Blackfan Anemia
Interventions: Procedure: Radiotherapy;   Drug: Alemtuzumab (Campath  );   Drug: Sirolimus (Rapamune  )
16 Recruiting Fertility Preservation in Women Who Will Have Gonadotoxic Therapy or Hematopoetic Stem Cell Transplantation, and in Women With Sickle Cell Disease
Conditions: Hemoglobin;   Stem Cell Transplant;   Aplastic Anemia
Intervention:
17 Recruiting Screening for Subjects to Participate in Studies of Blood Disorders
Conditions: Bone Marrow Transplant;   Sickle Cell Disease;   G-CSF
Intervention:
18 Recruiting MBSR for Pain Catastrophizing in SCD
Condition: Anemia, Sickle Cell
Intervention: Behavioral: Mindfulness-based Stress Reduction
19 Unknown  Longitudinal Changes in Exercise Capacity in Children and Young Adults With Sickle Cell Anemia
Condition: Sickle Cell Anemia
Intervention:
20 Unknown  Exercise Capacity in Pediatric Sickle Cell Anemia
Condition: Sickle Cell Anemia
Intervention:

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Indicates status has not been verified in more than two years