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39 studies found for:    sickle cell anemia OR sickle cell disease OR hemoglobin S disease OR hemoglobin SS disease | Open Studies | NIH, U.S. Fed
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Rank Status Study
1 Recruiting Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
Conditions: Pulmonary Hypertension;   Sickle Cell Anemia;   Sickle Cell Disease
Intervention:
2 Recruiting Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure
Conditions: Sickle Cell Disease;   Thalassemia;   Stem Cell Transplantation;   Graft vs Host Disease
Interventions: Drug: Alemtuzumab;   Drug: Sirolimus;   Drug: Cyclophosphamide;   Drug: Pentostatin;   Drug: Radiotherapy
3 Recruiting Collection and Storage of Umbilical Cord Stem Cells for Treatment of Sickle Cell Disease
Conditions: Sickle Cell Disease;   Sickle Cell Trait
Intervention:
4 Recruiting Natural History of Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention:
5 Recruiting Insights Into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers Study (INSIGHTS Study)
Conditions: Genetic Disease;   Genomics
Intervention:
6 Recruiting Evaluation of Sickle Cell Liver Disease
Condition: Sickle Cell Disease
Intervention:
7 Recruiting Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias
Conditions: Congenital Hemolytic Anemia;   Diamond-Blackfan Anemia
Interventions: Procedure: Radiotherapy;   Drug: Alemtuzumab (Campath );   Drug: Sirolimus (Rapamune )
8 Recruiting Longitudinal Changes in Exercise Capacity in Children and Young Adults With Sickle Cell Anemia
Condition: Sickle Cell Anemia
Intervention:
9 Recruiting Fludarabine, Cyclophosphamide, and Total-Body Irradiation Followed By Donor Bone Marrow Transplant in Treating Patients With Sickle Cell Anemia and Other Blood Disorders
Condition: Sickle Cell Disease
Interventions: Drug: cyclophosphamide;   Drug: fludarabine phosphate;   Drug: mycophenolate mofetil;   Drug: Sirolimus;   Procedure: Allogeneic bone marrow transplantation;   Radiation: total-body irradiation;   Drug: Levetiracetam
10 Recruiting Preventing Sickle Cell Kidney Disease
Conditions: Anemia, Sickle Cell;   Sickle Cell Disease;   Kidney Disease;   Hypertension;   Proteinuria
Intervention: Drug: Losartan
11 Recruiting Screening for Subjects to Participate in Studies of Blood Disorders
Conditions: Bone Marrow Transplant;   Sickle Cell Disease;   G-CSF
Intervention:
12 Recruiting The Genetics and Functional Basis of Inherited Platelet, White Blood Cell, Red Blood Cell, and Blood Clotting Disorders.
Condition: Glanzmann Thrombasthenia
Intervention:
13 Recruiting The Role of Endothelin-1 in Sickle Cell Disease
Condition: Sickle Cell Anemia
Interventions: Drug: Ambrisentan;   Drug: Placebo
14 Not yet recruiting Screening for Alpha Thalassemia in Healthy Volunteers
Condition: Alpha Thalassemia
Intervention:
15 Recruiting Molecular Immunohematology in Ethiopian Sub-Populations
Conditions: Blood Group Antigens;   Blood Grouping and Crossmatching
Intervention:
16 Recruiting Massive Iron Deposit Assessment
Conditions: Iron Overload;   Excessive Body Iron Burden
Interventions: Device: R2*-UTE;   Device: R2*-GRE;   Procedure: Liver biopsy
17 Recruiting Developing the Family Map: Looking at Communal Coping
Conditions: Diabetes;   Cancer;   Cardiovascular Disease;   Sickle Cell Disease
Intervention:
18 Not yet recruiting Omega-3 Fatty Acids in Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention: Drug: SCD-Omegatex™
19 Recruiting Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503)
Condition: Sickle Cell Disease
Interventions: Drug: Busulfan;   Drug: Fludarabine;   Drug: r-ATG;   Procedure: Bone Marrow Transplant;   Drug: Tacrolimus;   Drug: Methotrexate;   Procedure: Standard of Care
20 Recruiting Bone Marrow for Hemoglobinopathy Research
Conditions: Sickle Cell Anemia;   Thalassemia
Intervention:

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Study has passed its completion date and status has not been verified in more than two years.