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40 studies found for:    sickle cell anemia OR sickle cell disease OR hemoglobin S disease OR hemoglobin SS disease | Open Studies | NIH, U.S. Fed
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Rank Status Study
21 Recruiting PATient Navigator to rEduce Readmissions
Conditions: Chronic Obstructive Pulmonary Disease;   Heart Failure;   Sickle Cell Disease;   Myocardial Infarction;   Pneumonia
Interventions: Behavioral: Hospital usual care;   Behavioral: Patient Navigator;   Behavioral: Peer-led telephone support line
22 Recruiting Massive Iron Deposit Assessment
Conditions: Iron Overload;   Excessive Body Iron Burden
Interventions: Device: R2*-UTE;   Device: R2*-GRE;   Procedure: Liver biopsy
23 Recruiting The Genetics and Functional Basis of Inherited Platelet, White Blood Cell, Red Blood Cell, and Blood Clotting Disorders.
Condition: Glanzmann Thrombasthenia
Intervention:
24 Recruiting Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders
Condition: Non-Malignant
Interventions: Procedure: Allogeneic Bone Marrow Transplantation;   Biological: Anti-Thymocyte Globulin;   Drug: Cyclosporine;   Drug: Fludarabine Phosphate;   Other: Laboratory Biomarker Analysis;   Drug: Methotrexate;   Drug: Mycophenolate Mofetil;   Procedure: Peripheral Blood Stem Cell Transplantation;   Drug: Tacrolimus;   Radiation: Total-Body Irradiation;   Drug: Treosulfan;   Procedure: Umbilical Cord Blood Transplantation
25 Not yet recruiting Screening for Alpha Thalassemia in Healthy Volunteers
Condition: Alpha Thalassemia
Intervention:
26 Recruiting Molecular Immunohematology in Ethiopian Sub-Populations
Conditions: Blood Group Antigens;   Blood Grouping and Crossmatching
Intervention:
27 Not yet recruiting Introducing Fetal Scalp Stimulation as an Adjunct to Intermittent Auscultation in Low-Resource Settings.
Conditions: Fetal Distress;   Stillbirth;   Birth Asphyxia;   Acidosis
Intervention: Procedure: Fetal Scalp Stimulation
28 Recruiting Epidemiology of Burkitt Lymphoma in East Africa Children or Minors (EMBLEM)
Conditions: Lymphoma, Non-Hodgkin;   Malaria;   Herpesvirus 4, Human
Intervention:
29 Not yet recruiting Evaluating the Safety and Immunogenicity of HIV Clade C DNA Vaccine and MF59- or AS01B-Adjuvanted Clade C Env Protein Vaccines in Various Combinations in Healthy, HIV-Uninfected Adults
Condition: HIV Infections
Interventions: Biological: DNA-HIV-PT123 vaccine;   Biological: Bivalent Subtype C gp120/MF59 vaccine;   Biological: Bivalent Subtype C gp120/AS01B vaccine;   Biological: Placebo
30 Recruiting Tablet-Aided BehavioraL Intervention EffecT on Self-management Skills
Conditions: Diabetes Mellitus, Type 2;   Diabetes Mellitus, Adult-Onset;   Diabetes Mellitus, Non-Insulin-Dependent;   Diabetes Mellitus, Noninsulin Dependent;   Diabetes Mellitus, Type II
Intervention: Behavioral: Tablets Intervention
31 Not yet recruiting Ricolinostat, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable or Metastatic Cholangiocarcinoma
Conditions: Non-Resectable Cholangiocarcinoma;   Recurrent Cholangiocarcinoma;   Stage III Extrahepatic Bile Duct Cancer;   Stage III Intrahepatic Cholangiocarcinoma;   Stage IIIA Hilar Cholangiocarcinoma;   Stage IIIB Hilar Cholangiocarcinoma;   Stage IVA Extrahepatic Bile Duct Cancer;   Stage IVA Hilar Cholangiocarcinoma;   Stage IVA Intrahepatic Cholangiocarcinoma;   Stage IVB Extrahepatic Bile Duct Cancer;   Stage IVB Hilar Cholangiocarcinoma;   Stage IVB Intrahepatic Cholangiocarcinoma;   Unresectable Extrahepatic Bile Duct Carcinoma
Interventions: Drug: Cisplatin;   Drug: Gemcitabine Hydrochloride;   Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study;   Drug: Ricolinostat
32 Recruiting Treatment of Hemochromatosis
Condition: Hemochromatosis
Intervention:
33 Recruiting An Educational Intervention for Type 2 Diabetes Patients
Condition: Diabetes Mellitus
Interventions: Behavioral: Intervention Video;   Behavioral: Control
34 Recruiting Preventing Obesity in Military Communities-Adolescents
Conditions: Obesity;   Overweight;   Binge Eating
Interventions: Behavioral: Interpersonal Psychotherapy;   Other: Health Education
35 Recruiting Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain Imaging
Conditions: Neurovascular Coupling;   Hemoglobin;   Functional Brain Imaging
Intervention:
36 Recruiting Technology Intensified Diabetes Education Study in African Americans
Conditions: Diabetes Mellitus, Type 2;   Diabetes Mellitus, Adult-Onset;   Diabetes Mellitus, Non-Insulin-Dependent;   Diabetes Mellitus, Noninsulin Dependent;   Diabetes Mellitus, Type II
Intervention: Behavioral: Technology Intensified
37 Recruiting Latinos Combating Diabetes
Conditions: Pre Diabetes;   Obesity;   Metabolic Syndrome
Interventions: Behavioral: Lifestyle Weight Loss;   Behavioral: Counseling
38 Recruiting Early Gestational Diabetes Screening in the Gravid Obese Woman
Conditions: Gestational Diabetes;   Obesity
Intervention: Other: Early Screen
39 Recruiting Evaluating the Safety and Immunogenicity of PENNVAX®-GP DNA Vaccine and IL-12 Plasmid, Delivered Via Intradermal or Intramuscular Electroporation in Healthy, HIV-Uninfected Adults
Condition: HIV Infections
Interventions: Biological: PENNVAX®-GP HIV-1 DNA vaccine;   Biological: Interleukin-12 (IL-12) DNA adjuvant;   Biological: Placebo
40 Recruiting Extended Dosing With Eltrombopag for Severe Aplastic Anemia
Condition: Severe Aplastic Anemia (SAA)
Intervention: Drug: Eltrombopag

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