42 studies found for:    sickle cell anemia OR sickle cell disease OR hemoglobin S disease OR hemoglobin SS disease | Open Studies | NIH, U.S. Fed
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21 Recruiting Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503)
Condition: Sickle Cell Disease
Interventions: Drug: Busulfan;   Drug: Fludarabine;   Drug: r-ATG;   Procedure: Bone Marrow Transplant;   Drug: Tacrolimus;   Drug: Methotrexate;   Procedure: Standard of Care
22 Recruiting Bone Marrow for Hemoglobinopathy Research
Conditions: Sickle Cell Anemia;   Thalassemia
Intervention:
23 Recruiting Primary Prevention of Stroke in Children With SCD in Sub-Saharan Africa II
Conditions: Sickle Cell Disease;   Stroke
Interventions: Drug: Hydroxyurea (Moderate Dose);   Drug: Hydroxyurea (Low Dose)
24 Recruiting Enhancing Use of Hydroxyurea In Sickle Cell Disease Using Patient Navigators
Condition: Sickle Cell Disease
Interventions: Behavioral: Patient Navigator;   Behavioral: Recruitment into Specialty Care
25 Recruiting Hydroxyurea to Prevent Brain Injury in Sickle Cell Disease
Conditions: Sickle Cell Disease;   Stroke
Interventions: Drug: Hydroxyurea;   Drug: Placebo
26 Recruiting A Phase II Trial of Regadenoson in Sickle Cell Anemia
Condition: Sickle Cell Anemia
Interventions: Drug: Regadenoson;   Drug: Placebo
27 Recruiting Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders
Condition: Non-Malignant
Interventions: Procedure: Allogeneic Bone Marrow Transplantation;   Biological: Anti-Thymocyte Globulin;   Drug: Cyclosporine;   Drug: Fludarabine Phosphate;   Other: Laboratory Biomarker Analysis;   Drug: Methotrexate;   Drug: Mycophenolate Mofetil;   Procedure: Peripheral Blood Stem Cell Transplantation;   Drug: Tacrolimus;   Radiation: Total-Body Irradiation;   Drug: Treosulfan;   Procedure: Umbilical Cord Blood Transplantation
28 Not yet recruiting Introducing Fetal Scalp Stimulation as an Adjunct to Intermittent Auscultation in Low-Resource Settings.
Conditions: Fetal Distress;   Stillbirth;   Birth Asphyxia;   Acidosis
Intervention: Procedure: Fetal Scalp Stimulation
29 Recruiting Epidemiology of Burkitt Lymphoma in East Africa Children or Minors (EMBLEM)
Conditions: Lymphoma, Non-Hodgkin;   Malaria;   Herpesvirus 4, Human
Intervention:
30 Not yet recruiting mHealth for Diabetes Adherence Support
Condition: Diabetes Mellitus, Type 2
Intervention: Behavioral: mHealth for Diabetes Adherence Support
31 Recruiting Treatment of Hemochromatosis
Condition: Hemochromatosis
Intervention:
32 Recruiting An Educational Intervention for Type 2 Diabetes Patients
Condition: Diabetes Mellitus
Interventions: Behavioral: Intervention Video;   Behavioral: Control
33 Recruiting Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain Imaging
Conditions: Neurovascular Coupling;   Hemoglobin;   Functional Brain Imaging
Intervention:
34 Recruiting Tablet-Aided BehavioraL Intervention EffecT on Self-management Skills
Conditions: Diabetes Mellitus, Type 2;   Diabetes Mellitus, Adult-Onset;   Diabetes Mellitus, Non-Insulin-Dependent;   Diabetes Mellitus, Noninsulin Dependent;   Diabetes Mellitus, Type II
Intervention: Behavioral: Tablets Intervention
35 Recruiting Extended Dosing With Eltrombopag for Severe Aplastic Anemia
Condition: Severe Aplastic Anemia (SAA)
Intervention: Drug: Eltrombopag
36 Recruiting Preventing Obesity in Military Communities-Adolescents
Conditions: Obesity;   Overweight;   Binge Eating
Interventions: Behavioral: Interpersonal Psychotherapy;   Other: Health Education
37 Recruiting Early Gestational Diabetes Screening in the Gravid Obese Woman
Conditions: Gestational Diabetes;   Obesity
Intervention: Other: Early Screen
38 Recruiting Evaluating the Safety and Immunogenicity of HIV Clade C DNA Vaccine and MF59- or AS01B-Adjuvanted Clade C Env Protein Vaccines in Various Combinations in Healthy, HIV-Uninfected Adults
Condition: HIV Infections
Interventions: Biological: DNA-HIV-PT123 vaccine;   Biological: Bivalent Subtype C gp120/MF59 vaccine;   Biological: Bivalent Subtype C gp120/AS01B vaccine;   Biological: Placebo
39 Not yet recruiting Evaluating the Immunogenicity of the AIDSVAX B/E Vaccine and the MVA/HIV62B Vaccine in Healthy, HIV-1-Uninfected Adults Who Previously Received MVA/HIV62B in DNA/MVA or MVA/MVA Regimens in HVTN 205
Condition: HIV Infections
Interventions: Biological: MVA/HIV62B vaccine;   Biological: AIDSVAX B/E vaccine;   Biological: Placebo
40 Recruiting Rural Lifestyle Eating and Activity Program (Rural LEAP)
Condition: Obesity
Interventions: Behavioral: Lifestyle intervention;   Behavioral: Health education control;   Behavioral: Individual;   Behavioral: All Groups

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Study has passed its completion date and status has not been verified in more than two years.