54 studies found for:    sickle cell anemia OR sickle cell disease OR hemoglobin S disease OR hemoglobin SS disease | Open Studies | NIH, U.S. Fed
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Rank Status Study
21 Recruiting Retroviral Vector Mediated Globin Gene Transfer to Correct Sickle Cell Anemia or Thalassemia
Conditions: Sickle Cell Anemia;   Thalassemia
Intervention: Genetic: Gene Therapy
22 Recruiting Study of Beet Juice for Patients With Sickle Cell Anemia
Condition: Sickle Cell Anemia
Intervention: Drug: beet juice (Unbeetable)
23 Recruiting Enhancing Use of Hydroxyurea In Sickle Cell Disease Using Patient Navigators
Condition: Sickle Cell Disease
Interventions: Behavioral: Patient Navigator;   Behavioral: HU Offer and Dosing to MTD
24 Recruiting Hydroxyurea to Prevent Brain Injury in Sickle Cell Disease
Conditions: Sickle Cell Disease;   Stroke
Interventions: Drug: Hydroxyurea;   Drug: Placebo
25 Recruiting Fludarabine, Cyclophosphamide, and Total-Body Irradiation Followed By Donor Bone Marrow Transplant in Treating Patients With Sickle Cell Anemia and Other Blood Disorders
Condition: Sickle Cell Disease
Interventions: Drug: cyclophosphamide;   Drug: fludarabine phosphate;   Drug: mycophenolate mofetil;   Drug: Sirolimus;   Procedure: Allogeneic bone marrow transplantation;   Radiation: total-body irradiation;   Drug: Levetiracetam
26 Recruiting A New Reagent Assay Examining Natural Parvovirus B19 Infection in Sickle Cell Disease
Condition: Sickle Cell Disease
Interventions: Other: Blood draw;   Other: Nasopharyngeal wash
27 Not yet recruiting Arginine Therapy for Sickle Cell Disease Pain
Conditions: Sickle Cell Disease;   Vaso-occlusive Pain Event
Interventions: Drug: L-arginine;   Drug: L-arginine Loading Dose;   Other: Placebo
28 Recruiting A Phase II Trial of Regadenoson in Sickle Cell Anemia
Condition: Sickle Cell Anemia
Interventions: Drug: Regadenoson;   Drug: Placebo
29 Recruiting Vaporized Cannabis for Chronic Pain Associated With Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention: Drug: Cannabis
30 Recruiting Hydroxyurea Adherence for Personal Best in Sickle Cell Treatment: HABIT
Condition: Sickle Cell Disease
Interventions: Behavioral: Community Health Worker (CHW);   Behavioral: Education
31 Recruiting Preventing Sickle Cell Kidney Disease
Conditions: Anemia, Sickle Cell;   Sickle Cell Disease;   Kidney Disease;   Hypertension;   Proteinuria
Intervention: Drug: Losartan
32 Recruiting PATient Navigator to rEduce Readmissions
Conditions: Chronic Obstructive Pulmonary Disease;   Heart Failure;   Sickle Cell Disease;   Myocardial Infarction;   Pneumonia
Interventions: Behavioral: Hospital usual care;   Behavioral: Patient Navigator;   Behavioral: Peer-led telephone support line
33 Recruiting Massive Iron Deposit Assessment
Conditions: Iron Overload;   Excessive Body Iron Burden
Interventions: Device: R2*-UTE;   Device: R2*-GRE;   Procedure: Liver biopsy
34 Recruiting The Genetics and Functional Basis of Inherited Platelet, White Blood Cell, Red Blood Cell, and Blood Clotting Disorders.
Condition: Glanzmann Thrombasthenia
Intervention:
35 Recruiting Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders
Condition: Non-Malignant
Interventions: Procedure: Allogeneic Bone Marrow Transplantation;   Biological: Anti-Thymocyte Globulin;   Drug: Cyclosporine;   Drug: Fludarabine Phosphate;   Other: Laboratory Biomarker Analysis;   Drug: Methotrexate;   Drug: Mycophenolate Mofetil;   Procedure: Peripheral Blood Stem Cell Transplantation;   Drug: Tacrolimus;   Radiation: Total-Body Irradiation;   Drug: Treosulfan;   Procedure: Umbilical Cord Blood Transplantation
36 Recruiting Molecular Immunohematology in Ethiopian Sub-Populations
Conditions: Blood Group Antigens;   Blood Grouping and Crossmatching
Intervention:
37 Recruiting Epidemiology of Burkitt Lymphoma in East Africa Children or Minors (EMBLEM)
Conditions: Lymphoma, Non-Hodgkin;   Malaria;   Herpesvirus 4, Human
Intervention:
38 Recruiting Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
Conditions: Recurrent Adult Hodgkin Lymphoma;   Recurrent Adult T-Cell Leukemia/Lymphoma;   Refractory Childhood Hodgkin Lymphoma;   Stage I Adult Hodgkin Lymphoma;   Stage I Adult T-Cell Leukemia/Lymphoma;   Stage I Childhood Hodgkin Lymphoma;   Stage II Adult Hodgkin Lymphoma;   Stage II Adult T-Cell Leukemia/Lymphoma;   Stage II Childhood Hodgkin Lymphoma;   Stage III Adult Hodgkin Lymphoma;   Stage III Adult T-Cell Leukemia/Lymphoma;   Stage III Childhood Hodgkin Lymphoma;   Stage IV Adult Hodgkin Lymphoma;   Stage IV Adult T-Cell Leukemia/Lymphoma;   Stage IV Childhood Hodgkin Lymphoma
Interventions: Other: Anthropometry;   Other: Serum Biomarkers;   Other: Diagnostic/symptom checklist;   Procedure: Echocardiogram;   Other: 6 minute walk test (6MWT);   Behavioral: Participant Questionnaires (ages >14 years only)
39 Recruiting Evaluating the Safety and Immune Response to Three Different DNA HIV Vaccines Administered With a MVA-CMDR Boost Vaccine in Healthy, HIV-Uninfected Adults
Condition: HIV Infections
Interventions: Biological: DNA Nat-B env;   Biological: DNA CON-S env;   Biological: DNA Mosaic env;   Biological: MVA-CMDR;   Biological: Placebo for DNA Nat-B env;   Biological: Placebo for DNA CON-S env;   Biological: Placebo for DNA Mosaic env;   Biological: Placebo for MVA-CMDR
40 Recruiting Dinaciclib, Bortezomib, and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma
Condition: Recurrent Plasma Cell Myeloma
Interventions: Drug: Bortezomib;   Drug: Dexamethasone;   Drug: Dinaciclib;   Other: Laboratory Biomarker Analysis

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