262 studies found for:    scleroderma
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21 Recruiting Allogeneic Hematopoietic Cell Transplantation After Nonmyeloablative Conditioning for Patients With Severe Systemic Sclerosis
Conditions: Systemic Scleroderma;   Severe Systemic Sclerosis
Interventions: Drug: fludarabine phosphate;   Drug: Mycophenolic Acid;   Drug: tacrolimus;   Radiation: total-body irradiation;   Procedure: bone marrow transplantation;   Procedure: reduced intensity allogeneic hematopoietic stem cell transplantation;   Procedure: quality-of-life assessment;   Other: laboratory biomarker analysis;   Other: flow cytometry;   Procedure: biopsy;   Drug: cyclophosphamide
22 Completed Effectiveness and Safety of Lidocaine for Scleroderma
Condition: Scleroderma
Interventions: Drug: Lidocaine 2% without vessel constrictor;   Other: Placebo - physiological solution 0,9%
23 Recruiting Neuropsychiatric Scleroderma Study: Systematic Evaluation of Neuropsychiatric Involvement in Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention: Other: Magnetic resonance Imaging
24 Not yet recruiting Proof-of-concept Trial of IVA337 in Diffuse Cutaneous Systemic Sclerosis
Conditions: Scleroderma, Diffuse;   Diffuse Cutaneous Systemic Sclerosis
Interventions: Drug: IVA337;   Drug: Placebo
25 Enrolling by invitation Gastroesophageal Reflux Treatment in Scleroderma
Conditions: Gastroesophageal Reflux Disease;   Systemic Sclerosis;   Scleroderma
Interventions: Drug: Alginic acid;   Drug: placebo (for domperidone);   Drug: Domperidone;   Drug: placebo (of alginic acid)
26 Active, not recruiting Study of Pomalidomide (CC-4047) to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effectiveness for Subjects With Systemic Sclerosis With Interstitial Lung Disease
Conditions: Scleroderma, Systemic;   Sclerosis, Systemic;   Systemic Scleroderma;   Systemic Sclerosis
Interventions: Drug: Pomalidomide (CC-4047);   Drug: Placebo
27 Completed
Has Results
High Dose Cyclophosphamide for Treatment of Scleroderma
Condition: Scleroderma
Intervention: Drug: IV Cyclophosphamide
28 Recruiting Morphea in Adults and Children (MAC) Cohort Study: A Morphea Registry and DNA Repository
Conditions: Scleroderma, Localized;   Morphea;   Frontal Linear Scleroderma en Coup de Sabre;   Scleroderma, Circumscribed;   Scleroderma, Linear
Intervention: Other: Morphea
29 Enrolling by invitation Lower Urinary Tract Symptoms in Systemic Sclerosis
Conditions: Urinary Symptoms;   Systemic Sclerosis
Intervention:
30 Completed Effect of Bosentan on Skin Fibrosis in Patients With Systemic Sclerosis
Conditions: Systemic Scleroderma;   Skin Fibrosis;   Hand Functionality
Intervention: Drug: Bosentan (Tracleer)
31 Unknown  High Dose Intravenous N-Acetylcysteine Versus Iloprost for Early, Rapidly Progressive Diffuse Systemic Sclerosis
Condition: Scleroderma, Diffuse
Intervention: Drug: N-acetylcysteine (NAC)
32 Recruiting Scleroderma Treatment With Celution Processed Adipose Derived Regenerative Cells (STAR)
Conditions: Scleroderma;   Systemic Sclerosis;   Raynaud Phenomena;   Raynaud's Disease
Interventions: Device: Celution Device;   Other: Placebo
33 Terminated Proof of Concept Trial of Gleevec (Imatinib) in Active Diffuse Scleroderma
Condition: Scleroderma
Interventions: Drug: Imatinib mesylate;   Other: Placebo
34 Recruiting Scleroderma Lung: Role of Gastroesophageal Reflux, Microaspiration and Cough
Condition: Scleroderma Lung
Intervention:
35 Recruiting Multi-center, Web Based Observational Study of Pulmonary Hypertension in Scleroderma Patients
Conditions: Systemic Sclerosis;   Scleroderma;   Pulmonary Hypertension;   Pulmonary Arterial Hypertension
Intervention:
36 Not yet recruiting Effects of Probiotics on Gastrointestinal Symptoms and on the Immune System in Patients With Systemic Sclerosis
Conditions: Systemic Sclerosis;   Scleroderma
Interventions: Other: Probiotic;   Other: Placebo
37 Recruiting Endothelial Function in Patients With Scleroderma or Cirrhosis With and Without Pulmonary Hypertension
Condition: Pulmonary Hypertension
Intervention:
38 Terminated
Has Results
Placebo Controlled Trial of Bosentan in Scleroderma Patients
Conditions: Systemic Scleroderma;   Pulmonary Hypertension
Interventions: Drug: Bosentan;   Drug: Placebo
39 Completed Genesis of Scleroderma: Role of Environmental Factors in 100 Patients With Scleroderma and 300 Controls
Condition: Scleroderma
Intervention: Other: Questionnary for environmental factors research
40 Completed Premature Coronary Atherosclerosis in Scleroderma
Condition: Scleroderma
Intervention:

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Indicates status has not been verified in more than two years