Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
58 studies found for:    respiratory failure OR hypoxemic respiratory failure OR hypercapnic respiratory failure | Open Studies | NIH, U.S. Fed
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Rank Status Study
21 Recruiting Human Mesenchymal Stem Cells For Acute Respiratory Distress Syndrome (START)
Condition: Respiratory Distress Syndrome, Adult
Interventions: Biological: Allogeneic Bone Marrow-Derived Human Mesenchymal Stem Cells;   Biological: Plasma-Lyte A
22 Recruiting VentFree: A Novel Abdominal Stimulator to Assist With Ventilator Weaning
Conditions: COPD;   Weaning Failure
Intervention: Device: Functional neuromuscular electrical stimulation
23 Recruiting Safety and Efficacy of Investigational Anti-Influenza Immune Plasma in Treating Influenza
Conditions: Influenza A;   Influenza B
Interventions: Biological: Anti-Influenza  Immune Plasma;   Behavioral: Standard Care
24 Recruiting Oxygen Versus PAP for Treatment of Sleep Apnea in Chronic Heart Failure
Conditions: Heart Failure;   Sleep Apnea Syndromes
Interventions: Device: Continuous positive airway pressure;   Device: Adaptive pressure-support servo-ventilation;   Device: Nocturnal supplemental oxygen;   Behavioral: Healthy Lifestyle and Sleep Education
25 Recruiting Water and Sudafed in Autonomic Failure
Conditions: Shy-Drager Syndrome;   Multiple System Atrophy
Interventions: Drug: Pseudoephedrine + 480 ml water;   Drug: Pseudoephedrine + 50 ml water;   Other: Placebo + 480 ml water (optional);   Other: Placebo + 50 ml water (optional)
26 Recruiting Efficacy of Short-Course Antimicrobial Treatment for Children With Acute Otitis Media and Impact on Resistance
Condition: Acute Otitis Media
Interventions: Drug: Amoxicillin-Clavulanate (10 days);   Drug: Amoxicillin-Clavulanate 5 days, placebo 5 days
27 Unknown  Continuous Positive Airway Pressure Versus Noninvasive Ventilation in Patients With Overlap Syndrome
Conditions: Chronic Obstructive Pulmonary Disease;   Obstructive Sleep Apnea;   Overlap Syndrome
Intervention: Procedure: Bipap procedure
28 Recruiting PATient Navigator to rEduce Readmissions
Conditions: Chronic Obstructive Pulmonary Disease;   Heart Failure;   Sickle Cell Disease;   Myocardial Infarction;   Pneumonia
Interventions: Behavioral: Hospital usual care;   Behavioral: Patient Navigator;   Behavioral: Peer-led telephone support line
29 Unknown  Multicenter Trial for the Evaluation of a Fixed Dose Combined Tablet for the Treatment of Pulmonary Tuberculosis
Condition: Tuberculosis
Intervention: Drug: combined fixed dose combination
30 Recruiting Combination Chemotherapy With or Without Oregovomab Followed By Stereotactic Body Radiation Therapy and Nelfinavir Mesylate in Treating Patients With Locally Advanced Pancreatic Cancer
Conditions: Acinar Cell Adenocarcinoma of the Pancreas;   Duct Cell Adenocarcinoma of the Pancreas;   Recurrent Pancreatic Cancer;   Stage IA Pancreatic Cancer;   Stage IB Pancreatic Cancer;   Stage IIA Pancreatic Cancer;   Stage IIB Pancreatic Cancer;   Stage III Pancreatic Cancer
Interventions: Drug: gemcitabine hydrochloride;   Drug: leucovorin calcium;   Biological: oregovomab;   Drug: nelfinavir mesylate;   Radiation: stereotactic body radiation therapy;   Procedure: therapeutic conventional surgery;   Other: laboratory biomarker analysis;   Drug: fluorouracil
31 Recruiting Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Conditions: Infection;   Hypertension;   Anesthesia;   Pain;   Reflux;   Nausea;   Edema;   Hyperlipidemia;   Hypotension;   Hypercholesterolemia;   Sedation;   Anxiolysis;   Benzodiazepine Withdrawal;   Bipolar Disorder;   Autistic Disorder;   Schizophrenia;   Influenza Treatment or Prophylaxis;   Acute Decompensated Heart Failure;   Stable Angina;   Life-threatening Fungal Infections;   Nosocomial Pneumonia;   Community Acquired Pneumonia;   Acute Bacterial Exacerbation of Chronic Bronchitis;   Complicated Skin and Skin Structure Infections;   Uncomplicated Skin and Skin Structure Infections;   Chronic Bacterial Prostatitis;   Complicated Urinary Tract Infections;   Acute Pyelonephritis;   Uncomplicated Urinary Tract Infections;   Inhalational Anthrax (Post-Exposure)
Intervention: Drug: Ampicillin
32 Recruiting Phase II Investigation of Antimycobacterial Therapy on Progressive, Pulmonary Sarcoidosis
Condition: Sarcoidosis; Antimycobacterial Therapy;
Interventions: Drug: Levofloxacin;   Drug: Ethambutol;   Drug: Azithromycin;   Drug: Rifampin;   Drug: Placebo
33 Recruiting Steroids In Eosinophil Negative Asthma
Condition: Asthma
Interventions: Drug: Mometasone 220mcg BID;   Drug: Tiotropium Respimat 5mcg QD;   Drug: Placebo
34 Recruiting Combined Illness Management and Psychotherapy in Treating Depressed Elders
Conditions: Depression;   Heart Failure;   Chronic Obstructive Pulmonary Disease
Interventions: Behavioral: Combined Psychotherapy and Illness Management;   Behavioral: Illness Management Only
35 Not yet recruiting A Trial of Integrating SBRT With Targeted Therapy in Stage IV Oncogene-driven NSCLC
Conditions: Non-small Cell Lung Cancer Metastatic;   Targetable Oncogenes (EGFR, ALK, ROS1)
Intervention: Radiation: SBRT with protons or photons
36 Recruiting PAHTCH (Carvedilol)
Condition: Pulmonary Hypertension
Interventions: Drug: Carvedilol;   Drug: Carvedilol placebo
37 Recruiting Prevention of Serious Adverse Events Following Angiography
Conditions: Acute Renal Failure;   Kidney Disease;   Coronary Artery Disease
Interventions: Drug: IV isotonic saline;   Drug: IV isotonic bicarbonate;   Drug: N-acetylcysteine;   Drug: Placebo
38 Unknown  Study of Default Options in Advance Directives
Conditions: COPD;   Severe or Very Severe Airflow Obstruction and/or Receiving or Eligible to Receive Long-term Oxygen Therapy;   Idiopathic Pulmonary Fibrosis;   Other Interstitial Lung Disease Without Curative Therapy;   Congestive Heart Failure;   NYHA Class IV or NYHA Class III Plus 1 Hospitalization in the Past Year;   Malignancy;   Any Stage 3B or 4 Solid Tumor
Interventions: Other: Comfort Default AD forms;   Other: Life Extension Default AD forms;   Other: Standard Default AD forms
39 Not yet recruiting Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury
Conditions: Acute Lung Injury;   Sepsis
Intervention: Drug: Ascorbic Acid
40 Unknown  Randomized Study of Folic Acid Therapy for Hyperhomocysteinemia in Patients With End Stage Renal Disease Receiving Hemodialysis
Conditions: End Stage Renal Disease;   Hyperhomocysteinemia
Interventions: Drug: cyanocobalamin;   Drug: folic acid;   Drug: pyridoxine

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Indicates status has not been verified in more than two years