54 studies found for:    pontine glioma
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Rank Status Study
1 Recruiting Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma
Conditions: Diffuse Intrinsic Pontine Glioma;   Brainstem Glioma
Intervention:
2 Active, not recruiting Molecularly Determined Treatment of Diffuse Intrinsic Pontine Gliomas (DIPG)
Condition: Diffuse Intrinsic Pontine Glioma
Interventions: Drug: Bevacizumab;   Drug: Erlotinib;   Drug: Temozolomide;   Radiation: Irradiation
3 Completed Phase 2 Study of Nimotuzumab in Pediatric Recurrent Diffuse Intrinsic Pontine Glioma
Condition: Recurrent Diffuse Pontine Gliomas
Intervention: Biological: nimotuzumab (anti EGFR humanized monoclonal antibody)
4 Completed
Has Results
A Phase II Study of Pegylated Interferon Alfa 2b (PEG-Intron(Trademark)) in Children With Diffuse Pontine Gliomas
Condition: Diffuse Intrinsic Pontine Glioma
Interventions: Procedure: adjuvant therapy;   Biological: pegylated interferon alfa
5 Recruiting Intra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG).
Condition: Diffuse Intrinsic Pontine Glioma (DIPG)
Intervention: Drug: Melphalan hydrochloride
6 Active, not recruiting PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma
Conditions: Diffuse Intrinsic Pontine Glioma;   Progressive or Refractory High-Grade Glioma
Intervention: Drug: Crenolanib
7 Active, not recruiting A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas
Conditions: Newly Diagnosed High-Grade Gliomas;   Diffuse Intrinsic Pontine Glioma
Interventions: Drug: Temozolomide;   Drug: Bevacizumab;   Drug: Irinotecan
8 Recruiting Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)
Conditions: Diffuse Intrinsic Pontine Glioma;   High-grade Glioma
Interventions: Drug: Crizotinib;   Drug: Dasatinib
9 Terminated Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents
Condition: Gliomas
Interventions: Drug: Cilengitide;   Drug: Temozolomide
10 Recruiting Anti PD1 Antibody in Diffuse Intrinsic Pontine Glioma
Condition: DIPG
Intervention: Biological: MDV9300
11 Terminated Erivedge (Vismodegib) in the Treatment of Pediatric Patients With Refractory Pontine Glioma
Condition: Pontine Glioma
Intervention: Drug: Vismodegib
12 Suspended Imiquimod/Brain Tumor Initiating Cell (BTIC) Vaccine in Brain Stem Glioma
Condition: Diffuse Intrinsic Pontine Glioma
Interventions: Biological: Tumor Lysate Vaccine;   Drug: Imiquimod;   Radiation: Radiation therapy
13 Recruiting Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas
Conditions: Diffuse Intrinsic Pontine Glioma;   Anaplastic Astrocytoma;   High Grade Glioma
Interventions: Drug: Lenalidomide;   Radiation: XRT, 54-59.4 Gy
14 Recruiting A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
Conditions: Pilomyxoid Astrocytoma;   Pilocytic Astrocytoma;   Glioma, Astrocytic;   Optic Nerve Glioma;   Pleomorphic Xanthoastrocytoma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   Gliosarcoma;   Diffuse Intrinsic Pontine Glioma;   DIPG;   Low-grade Glioma;   Brainstem Glioma
Interventions: Drug: Mebendazole;   Drug: Vincristine;   Drug: Carboplatin;   Drug: Temozolomide;   Drug: Bevacizumab;   Drug: Irinotecan
15 Recruiting Study of Suberoylanilide Hydroxamic Acid (SAHA) With Temsirolimus in Children With Diffuse Intrinsic Pontine Glioma (DIPG)
Condition: Diffuse Intrinsic Pontine Glioma
Interventions: Drug: Vorinostat;   Radiation: Radiation Therapy;   Drug: Temsirolimus
16 Recruiting Convection-Enhanced Delivery of 124I-8H9 for Patients With Non-Progressive Diffuse Pontine Gliomas Previously Treated With External Beam Radiation Therapy
Conditions: Brain Cancer;   Brain Stem Glioma
Intervention: Radiation: Radioactive iodine-labeled monoclonal antibody 8H9
17 Recruiting Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication
Condition: Diffuse Intrinsic Pontine Glioma
Interventions: Drug: Erlotinib;   Drug: Everolimus;   Drug: Dasatinib
18 Completed Clinical Trial Evaluating the Combination of Vandetanib and Dasatinib During and After Radiation Therapy (RT) in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG)
Condition: Diffuse Intrinsic Pontine Glioma
Intervention: Drug: vandetanib and dasatinib
19 Not yet recruiting Administration of Ribociclib Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)
Conditions: High Grade Glioma;   Diffuse Intrinsic Pontine Glioma;   Bithalamic High Grade Glioma
Intervention: Drug: Ribociclib
20 Recruiting Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors
Conditions: Diffuse Intrinsic Pontine Glioma;   Brain Tumor, Recurrent;   Solid Tumor, Recurrent;   Neuroblastoma, Recurrent, Refractory;   Ewing Sarcoma, Recurrent, Refractory;   Rhabdomyosarcoma, Recurrent, Refractory;   Osteosarcoma, Recurrent, Refractory;   Rhabdoid Tumor, Recurrent, Refractory
Intervention: Drug: Abemaciclib

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Indicates status has not been verified in more than two years