64 studies found for:    pontine glioma
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Rank Status Study
1 Active, not recruiting Molecularly Determined Treatment of Diffuse Intrinsic Pontine Gliomas (DIPG)
Condition: Diffuse Intrinsic Pontine Glioma
Interventions: Drug: Bevacizumab;   Drug: Erlotinib;   Drug: Temozolomide;   Radiation: Irradiation
2 Recruiting Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma
Conditions: Diffuse Intrinsic Pontine Glioma;   Brainstem Glioma
Intervention:
3 Completed
Has Results
A Phase II Study of Pegylated Interferon Alfa 2b (PEG-Intron(Trademark)) in Children With Diffuse Pontine Gliomas
Condition: Diffuse Intrinsic Pontine Glioma
Interventions: Procedure: adjuvant therapy;   Biological: pegylated interferon alfa
4 Active, not recruiting A Study of Atengenal and Astugenal in Diffuse, Intrinsic Pontine Glioma (DIPG)
Condition: Diffuse, Intrinsic Pontine Glioma
Intervention: Drug: Antineoplaston therapy (Atengenal + Astugenal)
5 Recruiting Intra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG).
Condition: Diffuse Intrinsic Pontine Glioma (DIPG)
Intervention: Drug: Melphalan hydrochloride
6 Terminated
Has Results
Erivedge (Vismodegib) in the Treatment of Pediatric Patients With Refractory Pontine Glioma
Condition: Pontine Glioma
Intervention: Drug: Vismodegib
7 Completed Phase 2 Study of Nimotuzumab in Pediatric Recurrent Diffuse Intrinsic Pontine Glioma
Condition: Recurrent Diffuse Pontine Gliomas
Intervention: Biological: nimotuzumab (anti EGFR humanized monoclonal antibody)
8 Active, not recruiting Anti PD1 Antibody in Diffuse Intrinsic Pontine Glioma
Condition: DIPG
Intervention: Biological: MDV9300
9 Active, not recruiting Imiquimod/Brain Tumor Initiating Cell (BTIC) Vaccine in Brain Stem Glioma
Condition: Diffuse Intrinsic Pontine Glioma
Interventions: Biological: Tumor Lysate Vaccine;   Drug: Imiquimod;   Radiation: Radiation therapy
10 Completed PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma
Conditions: Diffuse Intrinsic Pontine Glioma;   Progressive or Refractory High-Grade Glioma
Intervention: Drug: Crenolanib
11 Recruiting Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)
Conditions: Diffuse Intrinsic Pontine Glioma;   High-grade Glioma
Interventions: Drug: Crizotinib;   Drug: Dasatinib
12 Recruiting Panobinostat in Treating Younger Patients With Progressive Diffuse Intrinsic Pontine Glioma
Condition: Diffuse Intrinsic Pontine Glioma
Interventions: Other: Laboratory Biomarker Analysis;   Drug: Panobinostat;   Other: Pharmacological Study
13 Completed Clinical Trial Evaluating the Combination of Vandetanib and Dasatinib During and After Radiation Therapy (RT) in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG)
Condition: Diffuse Intrinsic Pontine Glioma
Intervention: Drug: vandetanib and dasatinib
14 Recruiting Gemcitabine in Newly-Diagnosed Diffuse Intrinsic Pontine Glioma
Condition: Diffuse Intrinsic Pontine Glioma
Intervention: Drug: Gemcitabine
15 Recruiting Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication
Condition: Diffuse Intrinsic Pontine Glioma
Interventions: Drug: Erlotinib;   Drug: Everolimus;   Drug: Dasatinib
16 Recruiting Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma
Condition: Glioma
Intervention: Drug: LBH589
17 Active, not recruiting Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas
Conditions: Diffuse Intrinsic Pontine Glioma;   Anaplastic Astrocytoma;   High Grade Glioma
Interventions: Drug: Lenalidomide;   Radiation: XRT, 54-59.4 Gy
18 Terminated Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents
Condition: Gliomas
Interventions: Drug: Cilengitide;   Drug: Temozolomide
19 Recruiting Study of Suberoylanilide Hydroxamic Acid (SAHA) With Temsirolimus in Children With Diffuse Intrinsic Pontine Glioma (DIPG)
Condition: Diffuse Intrinsic Pontine Glioma
Interventions: Drug: Vorinostat;   Radiation: Radiation Therapy;   Drug: Temsirolimus
20 Active, not recruiting A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas
Conditions: Newly Diagnosed High-Grade Gliomas;   Diffuse Intrinsic Pontine Glioma
Interventions: Drug: Temozolomide;   Drug: Bevacizumab;   Drug: Irinotecan

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Study has passed its completion date and status has not been verified in more than two years.