27 studies found for:    poly iclc | Open Studies
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Rank Status Study
1 Recruiting Enhancement by Poly-ICLC During HIV-1 Infection
Condition: HIV-1 Infected Adults With Chronic HIV-1 Infection
Interventions: Drug: Arm A: Poly-ICLC;   Drug: Arm B: Normal Saline
2 Recruiting In Situ, Autologous Therapeutic Vaccination Against Solid Cancers With Intratumoral Hiltonol®
Conditions: Melanoma;   Head and Neck Cancer;   Sarcoma;   Non-Melanoma Skin Cancers
Intervention: Biological: Hiltonol
3 Recruiting A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas
Condition: Brain Tumors
Intervention: Drug: Poly ICLC
4 Recruiting In Situ Vaccine for Low-Grade Lymphoma: Combination of Intratumoral Flt3L and Poly-ICLC With Low-Dose Radiotherapy
Condition: Low-Grade B-cell Lymphoma
Interventions: Drug: rhuFlt3L/CDX-301;   Drug: Poly-ICLC
5 Recruiting Phase I/II Trial of IMA950 Multi-peptide Vaccine Plus Poly-ICLC in Glioblastoma
Condition: CNS Tumor, Adult
Interventions: Biological: IMA 950;   Biological: Poly ICLC;   Other: Immunomonitoring
6 Recruiting DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, and IDO1 Inhibitor INCB024360 in Treating Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer in Remission
Conditions: Fallopian Tube Carcinoma;   Ovarian Carcinoma;   Primary Peritoneal Carcinoma
Interventions: Biological: DEC-205/NY-ESO-1 Fusion Protein CDX-1401;   Drug: Poly ICLC;   Drug: IDO1 Inhibitor INCB024360;   Other: Pharmacological Study;   Other: Laboratory Biomarker Analysis
7 Recruiting A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction With Poly-ICLC in Pediatric Gliomas
Conditions: Newly Diagnosed Pediatric Pontine Glioma.;   Newly Diagnosed Pediatric High Grade Glioma.;   Recurrent Pediatric High Grade Glioma.;   Recurrent Pediatric Low Grade Glioma.
Interventions: Biological: HLA-A2 restricted glioma antigen peptides vaccine;   Biological: Poly-ICLC
8 Recruiting A Vaccine Trial for Low Grade Gliomas
Condition: Low Grade Glioma
Intervention: Biological: Experimental: HLA-A2 Restricted Glioma Antigen-Peptides with Poly-ICLC
9 Recruiting Safety Study of a Helper Peptide Vaccine Plus Adjuvant Combinations for the Treatment of Melanoma
Condition: Melanoma
Interventions: Biological: 6MHP;   Drug: Montanide ISA-51;   Drug: polyICLC;   Drug: Cyclophosphamide
10 Recruiting Neoepitope-based Personalized Vaccine Approach in Patients With Newly Diagnosed Glioblastoma
Conditions: Glioblastoma Multiforme;   Astrocytoma, Grade IV
Interventions: Biological: Personalized peptide vaccine;   Drug: Poly-ICLC;   Drug: Temozolomide
11 Recruiting Phase II Study With Hiltonol and Dendritic Cells in Solid Tumors
Condition: Neoplasms
Intervention: Biological: Hiltonol and autologous dendritic cells
12 Recruiting Poly ICLC, Radiation, and Romidepsin for Advanced Cutaneous T Cell Lymphoma
Condition: Cutaneous T-cell Lymphoma
Interventions: Drug: Romidepsin;   Drug: Poly ICLC;   Radiation: Focal lesional radiation
13 Not yet recruiting A Comparison of Matured Dendritic Cells and Montanide® in Study Subjects With High Risk of Melanoma Recurrence
Condition: Melanoma
Interventions: Biological: DC Vaccine;   Biological: Montanide Vaccine;   Biological: Poly-ICLC
14 Recruiting GAPVAC Phase I Trial in Newly Diagnosed Glioblastoma Patients
Condition: Glioblastoma
Interventions: Drug: APVAC1 vaccine plus Poly-ICLC and GM-CSF;   Drug: APVAC2 vaccine plus Poly-ICLC and GM-CSF
15 Recruiting Autologous OC-L Vaccine and Ovarian Cancer
Conditions: Primary Ovarian Cancer;   Fallopian Tube Cancer;   Primary Peritoneal Cancer
Interventions: Biological: OC-L;   Other: Montanide;   Other: poly-ICLC (Hiltonol),
16 Not yet recruiting Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma
Condition: Glioma - Recurrent Grade II
Intervention: Biological: GBM6-AD and poly-ICLC
17 Recruiting Phase I/II Trial of a Long Peptide Vaccine (LPV7) Plus TLR Agonists
Conditions: Melanoma;   Metastatic Melanoma;   Mucosal Melanoma
Interventions: Biological: Peptide Vaccine (LPV7) + Tetanus peptide;   Other: PolyICLC;   Other: Resiquimod;   Other: IFA
18 Recruiting Safety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma Multiforme
Conditions: Adult Brain Glioblastoma;   Glioblastoma Multiforme
Interventions: Biological: SL-701; poly-ICLC (polyinosinic-polycytidylic acid stabilized with polylysine and carboxymethyl cellulose);   Drug: Bevacizumab
19 Recruiting A Study of Varlilumab (Anti-CD27) and Ipilimumab and CDX-1401 in Patients With Unresectable Stage III or IV Melanoma
Condition: Unresectable Stage III or Stage IV Melanoma
Interventions: Drug: Combination of varlilumab and ipilimumab;   Drug: Cohort A: varlilumab & ipilimumab; Cohort B: varlilumab, ipilimumab, CDX-1401 & poly-ICLC
20 Recruiting A Phase I Study With a Personalized NeoAntigen Cancer Vaccine in Melanoma
Condition: Melanoma
Interventions: Biological: Poly-ICLC;   Biological: Peptides

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