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49 studies found for:    phenylbutyrate
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Rank Status Study
21 Completed Immune Reconstitution in HIV Disease (IREHIV)
Condition: HIV Infection
Interventions: Drug: vitamin D (cholecalciferol) and PBA (sodium phenylbutyrate);   Drug: Placebo tablets
22 Completed Azacitidine Plus Phenylbutyrate in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome
Conditions: Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases
Interventions: Drug: azacitidine;   Drug: sodium phenylbutyrate
23 Completed Phenylbutyrate Plus Azacitidine in Treating Patients With Acute Myeloid Leukemia, Myelodysplasia, Non-Hodgkin's Lymphoma, Multiple Myeloma, Non-small Cell Lung Cancer, or Prostate Cancer
Conditions: Leukemia;   Lung Cancer;   Lymphoma;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic Syndromes;   Prostate Cancer
Interventions: Drug: azacitidine;   Drug: sodium phenylbutyrate
24 Completed A Study of Glyceryl Tri-(4-phenylbutyrate) (GT4P)
Condition: Healthy
Interventions: Drug: HPN-100;   Drug: Ammonul;   Drug: Buphenyl
25 Completed Azacitidine Plus Phenylbutyrate in Treating Patients With Advanced or Metastatic Solid Tumors That Have Not Responded to Previous Treatment
Conditions: Lymphoma;   Small Intestine Cancer;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: azacitidine;   Drug: sodium phenylbutyrate
26 Completed Mechanism of Fatty Acid-induced Impairment of Glucose-simulated Insulin Secretion - Effect of Buphenyl
Conditions: Diabetes;   Insulin Resistance
Interventions: Drug: sodium phenylbutyrate;   Drug: Placebo
27 Not yet recruiting Glycerol Phenylbutyrate Corrector Therapy For CF (Cystic Fibrosis)
Condition: Cystic Fibrosis
Interventions: Drug: Ravicti low dose;   Drug: Ravicti high dose;   Drug: Placebo
28 Completed
Has Results
Efficacy and Safety of HPN-100 for the Treatment of Adults With Urea Cycle Disorders
Condition: Urea Cycle Disorders
Interventions: Drug: HPN-100;   Drug: Buphenyl (NaPBA)
29 No longer available Transition From Buphenyl to RAVICTI for the Therapy of Byler Disease
Condition: Byler Disease
Intervention: Drug: Glycerol phenylbutyrate
30 Completed Phenylbutyrate, Dexamethasone, and Sargramostim in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia
Condition: Leukemia
Interventions: Biological: sargramostim;   Drug: dexamethasone;   Drug: oral sodium phenylbutyrate
31 No longer available Buphenyl Therapy for Byler's Disease
Condition: Byler Disease
Intervention: Drug: Buphenyl
32 Unknown  Phenylbutyrate and Valganciclovir in Treating Patients With Relapsed or Refractory Epstein-Barr Virus-Positive Cancer
Conditions: Gastric Cancer;   Head and Neck Cancer;   Lymphoma;   Lymphoproliferative Disorder
Interventions: Drug: oral sodium phenylbutyrate;   Drug: valganciclovir;   Genetic: polymerase chain reaction;   Genetic: protein expression analysis;   Procedure: biopsy
33 Completed Phenylbutyrate in Proteinuric Nephropathies
Condition: Proteinuric Diseases
Interventions: Drug: PBA 7,5g/d;   Drug: PBA 15g/d
34 Completed 5-Azacytidine and Phenylbutyrate to Treat Severe Thalassemia
Condition: Beta Thalassemia
Intervention: Drug: 5-Azacytidine
35 Active, not recruiting A Study of the Safety, Efficacy and Pharmacokinetics of Glycerol Phenylbutyrate in Pediatric Subjects Under 2 Years of Age With Urea Cycle Disorders (UCDs)
Condition: Urea Cycle Disorder
Intervention: Drug: RAVICTI
36 Completed Use of Ravicti™ in Patients With MCAD Deficiency With the 985A>G (K304E) Mutation
Condition: Medium-chain Acyl-CoA Dehydrogenase (MCAD) Deficiency
Intervention: Drug: Ravicti
37 Completed Phenylbutyrate and Tretinoin in Treating Patients With Hematologic Cancer
Conditions: Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases
Interventions: Drug: sodium phenylbutyrate;   Drug: tretinoin
38 Completed Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders
Condition: Amino Acid Metabolism, Inborn Errors
Interventions: Drug: Sodium Benzoate;   Drug: Sodium Phenylacetate;   Drug: Sodium Phenylbutyrate;   Behavioral: Dietary Intervention
39 Not yet recruiting AMX0035 in Patients With Amyotrophic Lateral Sclerosis (ALS)
Conditions: Amyotrophic Lateral Sclerosis;   Motor Neuron Disease;   Neuromuscular Diseases;   Neurodegenerative Diseases;   Spinal Cord Diseases;   TDP-43 Proteinopathies;   Nervous System Diseases;   Central Nervous System Diseases
Interventions: Drug: AMX0035;   Other: Placebo
40 Completed A Study of Glyceryl Tri-(4-phenylbutyrate) Administered Orally as a Single Dose, and Twice Daily for Seven Consecutive Days to Subjects With Hepatic Impairment With Cirrhosis and to a Control Group
Conditions: Hepatic Encephalopathy;   Urea Cycle Disorders
Intervention: Drug: HPN-100

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Study has passed its completion date and status has not been verified in more than two years.