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44 studies found for:    perifosine
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Rank Status Study
1 Active, not recruiting Perifosine With Temsirolimus for Recurrent Pediatric Solid Tumors
Condition: Pediatric Solid Tumors
Intervention: Drug: perifosine + temsirolimus
2 Active, not recruiting Clinical and Molecular-Metabolic Phase II Trial of Perifosine for Recurrent/Progressive Malignant Gliomas
Conditions: Malignant Gliomas;   CNS;   Brain Cancer;   Cancer
Intervention: Drug: Perifosine
3 Completed
Has Results
Perifosine in Patients With Relapsed/Refractory Waldenstrom's Macroglobulinemia
Condition: Waldenstrom's Macroglobulinemia
Intervention: Drug: Perifosine
4 Completed Placebo-Controlled Study of Perifosine + Single Agent Chemotherapy for Metastatic Cancer Patients
Condition: Colon Cancer
Intervention: Drug: Perifosine in combination with capecitabine
5 Unknown  Open Label Trial of Perifosine in Patients Currently Being Treated on Perifosine Trials in Solid Tumors or Multiple Myeloma
Conditions: Non Small Cell Lung Cancer;   Solid Tumors;   Metastatic Breast Cancer;   Sarcomas
Intervention: Drug: Perifosine
6 Completed Ph II Study of Perifosine Plus Gleevec for Patients With GIST
Condition: Gastrointestinal Stromal Tumors
Interventions: Drug: Perifosine;   Drug: Imatinib Mesylate
7 Completed Trial of Two Schedules of Perifosine for Patients With Solid Tumors or Lymphomas
Conditions: Tumors;   Lymphomas
Interventions: Drug: Perifosine Daily Dose;   Drug: Perifosine
8 Active, not recruiting
Has Results
Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma
Conditions: Adult Anaplastic Astrocytoma;   Adult Anaplastic Oligodendroglioma;   Adult Diffuse Astrocytoma;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Adult Mixed Glioma;   Adult Oligodendroglioma;   Recurrent Adult Brain Neoplasm
Interventions: Other: Laboratory Biomarker Analysis;   Drug: Perifosine;   Drug: Temsirolimus;   Procedure: Therapeutic Conventional Surgery
9 Completed 7-Hydroxystaurosporine and Perifosine in Treating Patients With Relapsed or Refractory Acute Leukemia, Chronic Myelogenous Leukemia or High Risk Myelodysplastic Syndromes
Conditions: Accelerated Phase Chronic Myelogenous Leukemia;   Adult Acute Megakaryoblastic Leukemia (M7);   Adult Acute Minimally Differentiated Myeloid Leukemia (M0);   Adult Acute Monoblastic Leukemia (M5a);   Adult Acute Monocytic Leukemia (M5b);   Adult Acute Myeloblastic Leukemia With Maturation (M2);   Adult Acute Myeloblastic Leukemia Without Maturation (M1);   Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Adult Acute Myelomonocytic Leukemia (M4);   Adult Acute Promyelocytic Leukemia (M3);   Adult Erythroleukemia (M6a);   Adult Pure Erythroid Leukemia (M6b);   Blastic Phase Chronic Myelogenous Leukemia;   Myelodysplastic/Myeloproliferative Neoplasms;   Previously Treated Myelodysplastic Syndromes;   Recurrent Adult Acute Lymphoblastic Leukemia;   Recurrent Adult Acute Myeloid Leukemia;   Relapsing Chronic Myelogenous Leukemia;   Secondary Acute Myeloid Leukemia;   T-cell Adult Acute Lymphoblastic Leukemia;   Untreated Adult Acute Lymphoblastic Leukemia;   Untreated Adult Acute Myeloid Leukemia
Interventions: Drug: 7-hydroxystaurosporine;   Drug: perifosine;   Other: pharmacological study
10 Completed Ph II Study of Perifosine for Patients With Carcinoma of the Kidney
Condition: Kidney Cancer
Intervention: Drug: Perifosine
11 Completed A Phase 1/2 Trial of Perifosine in the Treatment of Non-Small Cell Lung Cancer
Condition: Non Small Cell Lung Cancer
Intervention: Drug: Perifosine
12 Completed Safety & Efficacy Study of Perifosine + Bortezomib +/- Dexamethasone for Multiple Myeloma Patients
Conditions: Multiple Myeloma;   Multiple Myeloma in Relapse
Interventions: Drug: Perifosine;   Drug: Bortezomib;   Drug: Dexamethasone
13 Completed
Has Results
Perifosine in Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Conditions: Chronic Lymphocytic Leukemia;   Small Lymphocytic Lymphoma
Intervention: Drug: perifosine
14 Terminated Assessment of Efficacy and Safety of Perifosine, Bortezomib and Dexamethasone in Multiple Myeloma Patients
Condition: Multiple Myeloma
Interventions: Drug: Perifosine;   Drug: Perifosine Placebo;   Drug: Bortezomib;   Drug: Dexamethasone
15 Completed Efficacy of Perifosine Alone and in Combination With Dexamethasone for Patients With Multiple Myeloma
Condition: Multiple Myeloma
Interventions: Drug: perifosine;   Drug: dexamethasone
16 Active, not recruiting Study of Single Agent Perifosine for Recurrent Pediatric Solid Tumors
Condition: Solid Tumors
Intervention: Drug: perifosine
17 Completed A Trial of Perifosine in Patients With Chemo-Insensitive Sarcomas
Conditions: Chondrosarcomas;   Alveolar Soft Part Sarcomas;   Extra Skeletal Myxoid Chondrosarcomas
Intervention: Drug: Perifosine
18 Completed A Phase II Trial of Perifosine Following Tyrosine Kinase Inhibitor (TKI) - Failure in Patients With Renal Cancer
Condition: Renal Cell Carcinoma
Intervention: Drug: Perifosine
19 Completed Perifosine + Sunitinib Malate for Patients With Advanced Cancers
Conditions: Renal Cancer;   GIST
Interventions: Drug: Perifosine;   Drug: Sunitinib Malate
20 Unknown  A Food Effect and QTc Study of Perifosine in Patients With Advanced Malignancies
Condition: Cancer
Intervention: Drug: perifosine

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