43 studies found for:    pediatric low grade gliomas
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Rank Status Study
1 Recruiting A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas
Condition: Brain Tumors
Intervention: Drug: Poly ICLC
2 Recruiting A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction With Poly-ICLC in Pediatric Gliomas
Conditions: Newly Diagnosed Pediatric Pontine Glioma.;   Newly Diagnosed Pediatric High Grade Glioma.;   Recurrent Pediatric High Grade Glioma.;   Recurrent Pediatric Low Grade Glioma.
Interventions: Biological: HLA-A2 restricted glioma antigen peptides vaccine;   Biological: Poly-ICLC
3 Active, not recruiting Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
Conditions: Glioma;   Neurofibromatosis Type 1;   Recurrent Childhood Pilocytic Astrocytoma;   Recurrent Childhood Visual Pathway Glioma
Interventions: Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study;   Drug: Selumetinib
4 Active, not recruiting Vinorelbine for Children With Progressive or Recurrent Low-grade Gliomas
Condition: Low-grade Glioma
Intervention: Drug: Vinorelbine
5 Recruiting PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children
Conditions: Pediatric Recurrent Progressive Low-grade Gliomas;   Pediatric Progressive Low-grade Gliomas
Intervention: Drug: Everolimus
6 Recruiting A Study to Determine Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib In Children and Adolescent Subjects
Condition: Neoplasms, Brain
Intervention: Drug: Dabrafenib
7 Recruiting A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
Conditions: Pilomyxoid Astrocytoma;   Pilocytic Astrocytoma;   Glioma, Astrocytic;   Optic Nerve Glioma;   Pleomorphic Xanthoastrocytoma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   Gliosarcoma;   Diffuse Intrinsic Pontine Glioma;   DIPG;   Low-grade Glioma;   Brainstem Glioma
Interventions: Drug: Mebendazole;   Drug: Vincristine;   Drug: Carboplatin;   Drug: Temozolomide;   Drug: Bevacizumab;   Drug: Irinotecan
8 Active, not recruiting
Has Results
Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma
Conditions: Childhood Cerebral Anaplastic Astrocytoma;   Childhood Oligodendroglioma;   Childhood Spinal Cord Neoplasm;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Medulloblastoma
Interventions: Biological: Bevacizumab;   Radiation: Fludeoxyglucose F-18;   Drug: Irinotecan Hydrochloride
9 Recruiting Phase I/II Study of MEK162 for Children With Ras/Raf Pathway Activated Tumors
Conditions: Low-Grade Gliomas;   Malignant Neoplasms, Brain;   Soft Tissue Neoplasms
Intervention: Drug: MEK162
10 Recruiting Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation
Conditions: Brain Tumor;   Low Grade Glioma;   Astrocytoma;   Ependymoma;   Ganglioglioma
Intervention: Radiation: Proton radiotherapy
11 Completed
Has Results
A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects
Conditions: Central Nervous System Tumors;   Brain Tumors
Intervention: Procedure: Radiation Therapy
12 Recruiting Study of Vinblastine in Combination With Nilotinib in Children, Adolescents, and Young Adults
Conditions: Refractory Low-grade Gliomas;   Recurrent Low-grade Gliomas
Interventions: Drug: Vinblastine + Nilotinib;   Drug: Vinblastine
13 Recruiting Study Of Vinblastine in Combination With Nilotinib in Children, Adolescents and Young Adults
Conditions: Refractory Low-grade Gliomas;   Recurrent Low-grade Gliomas
Interventions: Drug: Nilotinib;   Drug: Vinblastine
14 Completed
Has Results
Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas
Conditions: Glioma;   Low-grade Glioma;   Astrocytoma
Intervention: Drug: everolimus
15 Active, not recruiting Weekly Vinblastine for Chemotherapy Naive Children With Progressive Low Grade Glioma (PLGGs)
Condition: Glioma
Intervention: Drug: Vinblastine Sulphate
16 Active, not recruiting Radiation Therapy in Treating Young Patients With Gliomas
Conditions: Brain Tumor;   Central Nervous System Tumor
Intervention: Radiation: radiation therapy
17 Unknown  Magnetic Resonance Imaging in Treating Children With Progressive Low-Grade Astrocytoma
Condition: Brain and Central Nervous System Tumors
Interventions: Procedure: conventional surgery;   Procedure: magnetic resonance spectroscopic imaging;   Radiation: radiation therapy
18 Completed MicroRNAs in Patients With Neurofibromatosis Type 1
Conditions: Glioma;   Neurofibromatosis Type 1
Intervention:
19 Recruiting Study to Investigate Safety, Pharmacokinetic (PK), Pharmacodynamic (PD) and Clinical Activity of Trametinib in Subjects With Cancer or Plexiform Neurofibromas and Trametinib in Combination With Dabrafenib in Subjects With Cancers Harboring V600 Mutations
Condition: Cancer
Interventions: Drug: Trametinib;   Drug: Dabrafenib
20 Completed Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors
Conditions: Childhood Central Nervous System Germ Cell Tumor;   Childhood Choroid Plexus Tumor;   Childhood Craniopharyngioma;   Childhood Ependymoblastoma;   Childhood Grade I Meningioma;   Childhood Grade II Meningioma;   Childhood Grade III Meningioma;   Childhood High-grade Cerebellar Astrocytoma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Infratentorial Ependymoma;   Childhood Low-grade Cerebellar Astrocytoma;   Childhood Low-grade Cerebral Astrocytoma;   Childhood Medulloepithelioma;   Childhood Mixed Glioma;   Childhood Oligodendroglioma;   Childhood Supratentorial Ependymoma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Pineoblastoma;   Recurrent Childhood Subependymal Giant Cell Astrocytoma;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma
Interventions: Drug: O6-benzylguanine;   Drug: temozolomide;   Biological: filgrastim;   Other: pharmacological study;   Other: laboratory biomarker analysis

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Indicates status has not been verified in more than two years