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46 studies found for:    pediatric low grade gliomas
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Rank Status Study
1 Recruiting A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas
Condition: Brain Tumors
Intervention: Drug: Poly ICLC
2 Recruiting Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
Conditions: Glioma;   Neurofibromatosis Type 1;   Recurrent Childhood Pilocytic Astrocytoma;   Recurrent Childhood Visual Pathway Glioma
Interventions: Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study;   Drug: Selumetinib
3 Active, not recruiting Vinorelbine for Children With Progressive or Recurrent Low-grade Gliomas
Condition: Low-grade Glioma
Intervention: Drug: Vinorelbine
4 Recruiting A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction With Poly-ICLC in Pediatric Gliomas
Conditions: Newly Diagnosed Pediatric Pontine Glioma;   Newly Diagnosed Pediatric High Grade Glioma;   Recurrent Pediatric High Grade Glioma;   Recurrent Pediatric Low Grade Glioma
Interventions: Biological: HLA-A2 restricted glioma antigen peptides vaccine;   Biological: Poly-ICLC
5 Recruiting A Study to Determine Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib In Children and Adolescent Subjects
Condition: Neoplasms, Brain
Intervention: Drug: Dabrafenib
6 Active, not recruiting PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children
Conditions: Pediatric Recurrent Progressive Low-grade Gliomas;   Pediatric Progressive Low-grade Gliomas
Intervention: Drug: Everolimus
7 Recruiting A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
Conditions: Pilomyxoid Astrocytoma;   Pilocytic Astrocytoma;   Glioma, Astrocytic;   Optic Nerve Glioma;   Pleomorphic Xanthoastrocytoma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   Gliosarcoma;   Diffuse Intrinsic Pontine Glioma;   DIPG;   Low-grade Glioma;   Brainstem Glioma
Interventions: Drug: Mebendazole;   Drug: Vincristine;   Drug: Carboplatin;   Drug: Temozolomide;   Drug: Bevacizumab;   Drug: Irinotecan
8 Recruiting Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG)
Condition: Low Grade Glioma
Interventions: Drug: Vinblastine;   Drug: Bevacizumab
9 Completed
Has Results
A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects
Conditions: Central Nervous System Tumors;   Brain Tumors
Intervention: Procedure: Radiation Therapy
10 Completed
Has Results
Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma
Conditions: Childhood Cerebral Anaplastic Astrocytoma;   Childhood Oligodendroglioma;   Childhood Spinal Cord Neoplasm;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Medulloblastoma
Interventions: Biological: Bevacizumab;   Radiation: Fludeoxyglucose F-18;   Drug: Irinotecan Hydrochloride
11 Recruiting Phase I/II Study of MEK162 for Children With Ras/Raf Pathway Activated Tumors
Conditions: Low-Grade Gliomas;   Malignant Neoplasms, Brain;   Soft Tissue Neoplasms
Intervention: Drug: MEK162
12 Active, not recruiting Weekly Vinblastine for Chemotherapy Naive Children With Progressive Low Grade Glioma (PLGGs)
Condition: Glioma
Intervention: Drug: Vinblastine Sulphate
13 Completed
Has Results
Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas
Conditions: Glioma;   Low-grade Glioma;   Astrocytoma
Intervention: Drug: everolimus
14 Recruiting Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation
Conditions: Brain Tumor;   Low Grade Glioma;   Astrocytoma;   Ependymoma;   Ganglioglioma
Intervention: Radiation: Proton radiotherapy
15 Completed Effects of Vaccinations With HLA-A2-Restricted Glioma Antigen-Peptides in Combination With Poly-ICLC for Adults With High-Risk WHO Grade II Astrocytomas and Oligo-Astrocytomas
Conditions: Astrocytoma;   Oligo-Astrocytoma;   Glioma
Intervention: Biological: GAA/TT-peptide vaccine and poly-ICLC
16 Completed MicroRNAs in Patients With Neurofibromatosis Type 1
Conditions: Glioma;   Neurofibromatosis Type 1
Intervention:
17 Recruiting Study of Vinblastine in Combination With Nilotinib in Children, Adolescents, and Young Adults
Conditions: Refractory Low-grade Gliomas;   Recurrent Low-grade Gliomas
Interventions: Drug: Vinblastine + Nilotinib;   Drug: Vinblastine
18 Recruiting Study Of Vinblastine in Combination With Nilotinib in Children, Adolescents and Young Adults
Conditions: Refractory Low-grade Gliomas;   Recurrent Low-grade Gliomas
Interventions: Drug: Nilotinib;   Drug: Vinblastine
19 Recruiting Study to Investigate Safety, Pharmacokinetic (PK), Pharmacodynamic (PD) and Clinical Activity of Trametinib in Subjects With Cancer or Plexiform Neurofibromas and Trametinib in Combination With Dabrafenib in Subjects With Cancers Harboring V600 Mutations
Condition: Cancer
Interventions: Drug: Trametinib;   Drug: Dabrafenib
20 Active, not recruiting
Has Results
Radiation Therapy in Treating Young Patients With Gliomas
Conditions: Brain Tumor;   Central Nervous System Tumor
Intervention: Radiation: radiation therapy

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Study has passed its completion date and status has not been verified in more than two years.