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4 studies found for:    pcsk9 | The Medicines Company [Exact]
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Rank Status Study
1 Recruiting A Study of ALN-PCSSC in Participants With Homozygous Familial Hypercholesterolemia
Condition: Homozygous Familial Hypercholesterolemia
Interventions: Drug: ALN-PCSSC;   Drug: Standard of Care
2 Active, not recruiting Trial to Evaluate the Effect of ALN-PCSSC Treatment on Low Density Lipoprotein Cholesterol (LDL-C)
Conditions: Atherosclerotic Cardiovascular Disease;   Familial Hypercholesterolemia;   Diabetes
Intervention: Drug: ALN-PCSSC
3 Not yet recruiting An Extension Trial of Inclisiran Compared to Evolocumab in Participants With Cardiovascular Disease and High Cholesterol
Conditions: Atherosclerotic Cardiovascular Disease;   Symptomatic Atherosclerosis;   Type2 Diabetes;   Familial Hypercholesterolemia
Interventions: Drug: Inclisiran;   Drug: Evolocumab
4 Completed A Phase 1 Study of an Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C)
Condition: Hypercholesterolemia
Interventions: Drug: ALN-PCSSC;   Drug: Sterile Normal Saline (0.9% NaCl)

Study has passed its completion date and status has not been verified in more than two years.