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297 studies found for:    p53
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Rank Status Study
1 Unknown  Surgery Combined With rAd-p53 Gene in Treatment Advanced Non-small-cell Carcinoma
Condition: Non-small Cell Lung Cancer
Interventions: Drug: Surgery combined with rAd-p53 gene therapy;   Procedure: Surgery
2 Unknown  rAd-p53 Gene Therapy for Advanced Oral and Maxillofacial Malignant Tumors
Condition: Advanced Oral and Maxillofacial Malignant Tumors
Interventions: Drug: p53 gene with surgery;   Procedure: surgery;   Drug: p53 with chemotherapy;   Drug: p53 gene therapy
3 Completed p53 Synthetic Long Peptides Vaccine With Cyclophosphamide for Ovarian Cancer
Condition: Ovarian Cancer
Interventions: Drug: P53-SLP vaccine;   Drug: Cyclophosphamide
4 Not yet recruiting p53 Gene Therapy in Treatment of Diabetes Concurrent With Hepatocellular Carcinoma
Conditions: HCC;   Diabetes
Interventions: Drug: p53 gene therapy;   Drug: Trans-catheter embolization
5 Not yet recruiting P53 Gene Combined With Radio- and Chemo-therapy in Treatment of Unresectable Locally Advanced Head and Neck Cancer
Condition: Advanced Head and Neck Cancer
Interventions: Drug: rAd-p53;   Radiation: radiation;   Drug: Cisplatin
6 Not yet recruiting p53 Gene in Treatment of Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer
Conditions: Ovarian Epithelial Cancer;   Fallopian Tube Cancer;   Primary Peritoneal Cancer
Interventions: Drug: p53 gene;   Drug: Cisplatin;   Drug: Paclitaxel
7 Active, not recruiting p53MVA Vaccine and Gemcitabine Hydrochloride in Treating Patients With Recurrent Ovarian Epithelial Cancer
Conditions: Recurrent Ovarian Epithelial Cancer;   Recurrent Fallopian Tube Carcinoma;   Recurrent Primary Peritoneal Carcinoma
Interventions: Biological: modified vaccinia virus ankara vaccine expressing p53;   Drug: gemcitabine hydrochloride;   Other: laboratory biomarker analysis
8 Unknown  p53 Gene Therapy for Head and Neck Malignant Tumors in Advanced Stage
Condition: Neoplasms
Interventions: Drug: chemotherapy plus p53;   Drug: chemotherapy;   Radiation: radiotherapy
9 Not yet recruiting Recombinant Adenoviral Human p53 Gene in Treatment of Malignant Pleural Effusion
Condition: Malignant Pleural Effusion
Interventions: Drug: rAdp53;   Drug: Cisplatin;   Drug: rAdp53 plus cisplatin
10 Recruiting Trans-catheter Chemo-embolization Combined With rAd-p53 Gene Injection in Treatment of Advanced Hepatocellular Carcinoma
Condition: Advanced Adult Hepatocellular Carcinoma
Interventions: Drug: TACE plus rAd-p53 artery injection;   Drug: TACE
11 Terminated
Has Results
Autologous SCT Followed by Dendritic Cell p53 Vaccination in Patients With Limited Stage Small Cell Lung Cancer
Condition: Small Cell Lung Cancer
Intervention: Biological: Combined adenovirus vectored p53 tranfected dedritic cell vaccine and ex vivo expanded T-lymphocytes
12 Completed Chemo-immunotherapy (Gemcitabine, Interferon-alpha 2b and p53 SLP) in Patients With Platinum-resistant Ovarian Cancer
Condition: Recurrent Ovarian Cancer
Interventions: Drug: Interferon Alfa-2b;   Biological: p53 SLP
13 Recruiting Safety and Efficacy of Intra-Arterial Ad-p53 in Liver Metastases of Solid Tumors
Condition: Metastatic Solid Tumor Cancer
Interventions: Drug: Ad-P53;   Drug: Xeloda
14 Unknown  rAd-p53 Gene Therapy for Advanced Malignant Thyroid Tumors
Condition: Advanced Malignant Thyroid Tumors
Interventions: Drug: rAd-p53 gene;   Procedure: surgery;   Drug: p53 gene therapy;   Radiation: p53 gene therapy with radioactive iodine
15 Not yet recruiting P53MVA and Pembrolizumab in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Conditions: PD-L1 Positive;   Recurrent Fallopian Tube Carcinoma;   Recurrent Ovarian Carcinoma;   Recurrent Primary Peritoneal Carcinoma;   TP53 Gene Mutation
Interventions: Other: Laboratory Biomarker Analysis;   Biological: Modified Vaccinia Virus Ankara Vaccine Expressing p53;   Biological: Pembrolizumab
16 Recruiting Trial of Adoptive T Cell Therapy With Activated P53 Specific T Cells for Treatment of Advanced Colorectal Cancer
Condition: Colorectal Carcinoma
Intervention: Biological: re-activated T cells
17 Completed Gene Therapy in Treating Patients With Advanced Bladder Cancer
Conditions: Recurrent Bladder Cancer;   Stage I Bladder Cancer;   Stage II Bladder Cancer;   Stage III Bladder Cancer;   Stage IV Bladder Cancer;   Transitional Cell Carcinoma of the Bladder
Intervention: Biological: Ad5CMV-p53 gene
18 Recruiting Trans-catheter Arterial Embolization Combined With p53 Gene Therapy for Treatment of Advanced Hepatocellular Carcinoma
Condition: Advanced Hepatocellular Carcinoma (HCC)
Interventions: Drug: TAE plus P53 gene;   Other: TAE
19 Recruiting Role of p53 Gene in Metabolism Regulation in Patients With Li-Fraumeni Syndrome
Condition: Li-Fraumeni Syndrome
Intervention:
20 Withdrawn CT-011 and p53 Genetic Vaccine for Advanced Solid Tumors
Conditions: Breast Cancer;   Colon Cancer;   Pancreatic Cancer;   Sarcoma;   Ovarian Cancer
Interventions: Biological: p53: 264-272 peptide;   Drug: CT-011

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Study has passed its completion date and status has not been verified in more than two years.