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66 studies found for:    ovarian small cell carcinoma | Open Studies | Interventional Studies
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Rank Status Study
1 Recruiting A Phase II, Multicenter Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumors or Relapsed/Refractory Synovial Sarcoma
Conditions: Malignant Rhabdoid Tumors (MRT);   Rhabdoid Tumors of the Kidney (RTK);   Atypical Teratoid Rhabdoid Tumors (ATRT);   Selected Tumors With Rhabdoid Features;   Synovial Sarcoma;   INI1-negative Tumors;   Malignant Rhabdoid Tumor of Ovary;   Renal Medullary Carcinoma;   Epithelioid Sarcoma;   Any Solid Tumor With an EZH2 GOF Mutation
Intervention: Drug: Tazemetostat
2 Recruiting LCL161 Plus Topotecan for Patients With Relapsed/Refractory Small Cell Lung Cancer and Select Gynecologic Malignancies
Conditions: Small Cell Lung Cancer;   Ovarian Cancer
Interventions: Drug: LCL161;   Drug: Topotecan
3 Recruiting RRx-001 in Small, Non-small Cell Lung Cancer, Ovarian Cancer and Neuroendocrine Tumors Prior to Re-administration of Platinum Based Doublet Regimens (QUADRUPLE THREAT)
Conditions: Small Cell Lung Carcinoma;   Carcinoma, Non-Small-Cell Lung;   Neuroendocrine Tumors;   Ovarian Epithelial Cancer
Interventions: Drug: RRx-001;   Drug: Cisplatin/carboplatin plus albumin (nab-paclitaxel or Abraxane);   Drug: cisplatin/carboplatin plus etoposide;   Drug: carboplatin/paclitaxel.
4 Recruiting AZD1775 Combined With Olaparib in Patients With Refractory Solid Tumors
Condition: Ovarian, Breast, and Second-Line Small Cell Lung Cancer
Interventions: Drug: AZD1775;   Drug: Olaparib
5 Recruiting Trial of Topotecan With VX-970, an ATR Kinase Inhibitor, in Small Cell Cancers
Conditions: Carcinoma, Non-Small -Cell Lung;   Ovarian Neoplasms;   Small Cell Lung Carcinoma;   Uterine Cervical Neoplasms;   Carcinoma, Neuroendocrine
Interventions: Drug: Topotecan;   Drug: VX-970
6 Recruiting Dose Finding Study Of PF-05212384 With Paclitaxel And Carboplatin In Patients With Advanced Solid Tumor
Conditions: Breast Cancer;   NSCLC;   Ovary Cancer;   Endometrial Cancer;   Small Cell Lung Cancer (SCLC);   Head and Neck (HNSCC)
Interventions: Drug: PF-05212384;   Drug: Paclitaxel;   Drug: Carboplatin
7 Recruiting Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors
Conditions: Small Cell Lung Carcinoma;   Carcinoma, Squamous Cell of Head and Neck;   Stomach Neoplasms;   Triple Negative Breast Neoplasms;   Ovarian Neoplasms;   Fallopian Tube Neoplasms;   Peritoneal Neoplasms;   Esophagogastric Junction Neoplasms
Interventions: Drug: paclitaxel + carboplatin;   Drug: carboplatin + etoposide;   Drug: gemcitabine + carboplatin;   Drug: nab-paclitaxel (paclitaxel-albumin) + carboplatin;   Drug: oxaliplatin + 5-fluorouracil (5FU) + leucovorin (calcium folinate/folinic acid);   Biological: durvalumab;   Biological: tremelimumab
8 Recruiting Study of Pembrolizumab Plus Chemotherapy in Patients With Advanced Cancer (PembroPlus)
Conditions: Advanced Cancer;   Breast Cancer;   Sarcoma;   Pancreatic Cancer;   Small Cell Lung Cancer;   Ovarian
Interventions: Drug: Pembrolizumab;   Drug: Gemcitabine;   Drug: Docetaxel;   Drug: Nab-paclitaxel;   Drug: Vinorelbine;   Drug: Irinotecan;   Drug: Liposomal Doxorubicin
9 Recruiting Phase 1 Study of Intradermal LV305 in Patients With Locally Advanced, Relapsed or Metastatic Cancer Expressing NY-ESO-1
Conditions: Melanoma - Currently Enrolling;   Non-small Cell Lung Cancer - Enrollment Completed;   Ovarian Candcer - Enrollment Completed;   Sarcoma - Enrollment Completed
Intervention: Biological: ID-LV305
10 Recruiting Study of Carfilzomib With Irinotecan in Irinotecan-Sensitive Malignancies and Small Cell Lung Cancer Patients
Conditions: Small Cell Lung Carcinoma;   Non Small Cell Lung Carcinoma;   Irinotecan Sensitive Cancers
Interventions: Drug: Carfilzomib;   Drug: Irinotecan
11 Recruiting Phase I/II Study of IMMU-132 in Patients With Epithelial Cancers
Conditions: Colorectal Cancer;   Gastric Adenocarcinoma;   Esophageal Cancer;   Hepatocellular Carcinoma;   Non-small Cell Lung Cancer;   Small Cell Lung Cancer;   Ovarian Epithelial Cancer;   Carcinoma Breast Stage IV;   Hormone-refractory Prostate Cancer;   Pancreatic Ductal Adenocarcinoma;   Head and Neck Cancers- Squamous Cell;   Renal Cell Cancer;   Urinary Bladder Neoplasms;   Cervical Cancer;   Endometrial Cancer;   Follicular Thyroid Cancer;   Glioblastoma Multiforme
Intervention: Drug: IMMU-132
12 Recruiting A Study of Nivolumab by Itself or Nivolumab Combined With Ipilimumab in Patients With Advanced or Metastatic Solid Tumors
Condition: Advanced or Metastatic Solid Tumors
Interventions: Biological: Nivolumab;   Biological: Ipilimumab;   Drug: Cobimetinib
13 Recruiting A Study Evaluating MM-310 in Patients With Solid Tumors
Conditions: Solid Tumors;   Urothelial Carcinoma;   Gastric Carcinoma;   Squamous Cell Carcinoma of the Head and Neck;   Ovarian Cancer;   Pancreatic Ductal Adenocarcinoma;   Prostate Adenocarcinoma;   Non-small Cell Lung Cancer;   Small Cell Lung Cancer;   Triple Negative Breast Cancer;   Endometrial Carcinoma;   Soft Tissue Sarcoma
Intervention: Drug: MM-310
14 Recruiting A Phase I/II Study of MEDI4736 in Combination With Olaparib in Patients With Advanced Solid Tumors.
Conditions: Ovarian;   Breast;   SCLC;   Gastric Cancers
Interventions: Drug: Olaparib;   Drug: MEDI4736
15 Recruiting Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies
Conditions: Hematological Neoplasms;   Non-Hodgkin's Lymphoma;   Hodgkin's Lymphoma;   Lymphoma;   Multiple Myeloma;   Acute Myeloid Leukemia;   Leukemia;   Myelodysplastic Syndromes;   Neoplasms;   Melanoma;   Breast Cancer;   Metastatic Breast Cancer;   Non-Small Cell Lung Cancer;   Small Cell Lung Cancer;   Renal Cell Carcinoma;   Glioblastoma Multiforme;   Osteosarcoma;   Sarcoma;   Thyroid Cancer;   Genitourinary
Interventions: Drug: CC-486;   Drug: Vidaza
16 Recruiting A Randomized Study of Safety and Efficacy of Pazopanib and Gemcitabine in Persistent or Relapsed Ovarian Cancer
Conditions: Ovarian Cancer;   Fallopian Tube Cancer;   Peritoneal Cancer
Interventions: Drug: Gemcitabine;   Drug: pazopanib
17 Recruiting Intraoperative Imagery of Renal Nodules With Folate-fluorescein Conjugate(EC17)
Condition: Renal Cell Carcinoma
Intervention: Drug: EC17
18 Recruiting A Study of ABBV-181 in Participants With Advanced Solid Tumors
Condition: Advanced Solid Tumors
Intervention: Drug: ABBV-181
19 Recruiting A Study of the Safety, Tolerability and Pharmacokinetics of ABBV-368 as a Single Agent and Combination in Subjects With Locally Advanced or Metastatic Solid Tumors
Condition: Advanced or Metastatic Solid Tumors
Interventions: Drug: ABBV-368;   Drug: Nivolumab
20 Recruiting Vaccine Therapy in Treating Patients With Stage IIIC-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer Following Surgery and Chemotherapy
Conditions: Fallopian Tube Clear Cell Adenocarcinoma;   Fallopian Tube Endometrioid Tumor;   Fallopian Tube Mucinous Neoplasm;   Fallopian Tube Serous Neoplasm;   Fallopian Tube Transitional Cell Carcinoma;   Ovarian Clear Cell Cystadenocarcinoma;   Ovarian Endometrioid Adenocarcinoma;   Ovarian Mucinous Cystadenocarcinoma;   Ovarian Seromucinous Carcinoma;   Ovarian Serous Cystadenocarcinoma;   Ovarian Transitional Cell Carcinoma;   Primary Peritoneal Serous Adenocarcinoma;   Recurrent Fallopian Tube Carcinoma;   Recurrent Ovarian Carcinoma;   Recurrent Primary Peritoneal Carcinoma;   Stage IIIC Fallopian Tube Cancer;   Stage IIIC Ovarian Cancer;   Stage IIIC Primary Peritoneal Cancer;   Stage IV Fallopian Tube Cancer;   Stage IV Ovarian Cancer;   Stage IV Primary Peritoneal Cancer;   Undifferentiated Fallopian Tube Carcinoma;   Undifferentiated Ovarian Carcinoma
Interventions: Other: Laboratory Biomarker Analysis;   Biological: Multi-epitope Folate Receptor Alpha-loaded Dendritic Cell Vaccine

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Study has passed its completion date and status has not been verified in more than two years.