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460 studies found for:    opioid receptors
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Rank Status Study
1 Recruiting Fast-Fail Trials in Mood and Anxiety Spectrum Disorders; Kappa Opioid Receptor Phase 2a
Condition: ANXIETY DISORDERS (or Anxiety and Phobic Neuroses)
Interventions: Drug: CERC-501;   Drug: placebo
2 Terminated A Study Of Kappa Opioid Receptor Occupancy Of PF-04455242, Using PET (Positron Emission Tomography)
Conditions: Bipolar Disorder;   Depression
Intervention: Drug: PF-04455242
3 Completed
Has Results
Mu-Opioid Receptor Genetic Polymorphism and Intrathecal Analgesia
Conditions: Labor Pain;   Post-cesarean Delivery
Intervention: Procedure: Blood Draw
4 Withdrawn FASTMAS (Fast-Fail Trials in Mood and Anxiety Spectrum Disorders) Kappa Opioid Receptor Phase 1 Study
Condition: Anxiety Disorders
Intervention: Drug: LY2456302
5 Completed A Study of Brain Receptor Occupancy in Healthy Subjects
Condition: Alcohol Dependence
Intervention: Drug: opioid receptor kappa antagonist
6 Completed [11C]Carfentanil PET Study of GSK1521498
Condition: Obesity
Interventions: Drug: Part A Assessing GSK1521498;   Drug: Part B Assessing GSK1521498;   Drug: Part C Assessing Naltrexone
7 Terminated Kappa Opioid Receptor Imaging in Depression (KOR Depression)
Conditions: Major Depressive Disorder;   Anhedonia
Intervention: Other: Positron Emission Tomography (PET) imaging
8 Terminated Kappa Opioid Receptor Imaging in Post-traumatic Stress Disorder (PTSD)
Conditions: Post-traumatic Stress Disorder (PTSD);   Trauma
Intervention: Other: Positron emission tomography (PET) imaging
9 Recruiting μ-opioid Receptor Polymorphism and Opioid Analgesia
Condition: Pharmacogenetic and Duration of Labor Fentanyl Analgesia.
Intervention: Drug: Fentanyl
10 Recruiting Evaluation of Brain Opioid Receptor Activity in Anorexia Nervosa : a PET [11C]Diprenorphine Study
Conditions: Body Dysmorphic Disorders;   Anorexia
Intervention: Drug: Positron Emission Tomography using [11C]diprenorphine
11 Completed Effects of Smoking on Opioid Receptor Binding: A PET Study
Condition: Substance-related Discorder
Interventions: Drug: Nicotine;   Drug: Carfentanil
12 Recruiting Title: Effect of Opioid Receptor Modulation on Alcohol Self-Administration and Neural Response to Alcohol Cues in Heavy Drinkers: Role of OPRM1 Gene Variation
Condition: Alcohol Drinking
Interventions: Drug: Nalmefene;   Other: Placebo
13 Completed To Evaluate the Influence of the A118G Polymorphism in the mu Opioid Receptor Gene (OPRM1) on Effects of GSK1521498 and Naltrexone on Physiological and Behavioural Markers of Brain Function in Healthy Social Drinkers
Condition: Alcoholism
Interventions: Drug: GSK1521498;   Drug: Naltrexone (NTX);   Drug: Placebo
14 Completed Dopamine and Opioid Receptor Antagonists Reduce Cue-induced Reward Responding and Reward Impulsivity
Condition: Addiction
Interventions: Drug: Placebo;   Drug: Amisulpride;   Drug: Naltrexone
15 Unknown  Decision Making Deficit and DNA Methylation in Opioid Receptor Genes Among Community Heroin Addicts
Condition: Heroin Addiction
Intervention:
16 Recruiting Mu Opioid Receptor Genes, Remifentanil, and Pain Sensitivity
Conditions: Polymorphism-Genetic;   Pain;   Allelic Frequencies of Genetic Markers
Interventions: Genetic: OPRM1 AA118;   Drug: Morphine;   Drug: Placebo;   Genetic: OPRM1 GX118
17 Terminated Kappa Opioid Receptor Imaging in Anorexia
Condition: Anorexia Nervosa
Intervention: Other: Positron emission tomography (PET) imaging
18 Enrolling by invitation Impact of Delta Opioid Receptor Gene (OPRD1) Variations on Treatment Outcome in African Americans
Conditions: Genetic Underpinning of Substance Abuse;   Polymorphism-genetic;   Drug Abuse/Dependence;   Opiod-Related Disorders
Intervention:
19 Completed Prevention of Stimulant-Induced Euphoria With an Opioid Receptor Antagonist
Conditions: ADHD;   Stimulant-Induced Euphoria
Interventions: Drug: SODAS MPH;   Drug: Naltrexone
20 Suspended Opioid Receptors Influence Ischemia-Reperfusion Injury
Condition: Ischemia-Reperfusion Injury
Interventions: Drug: morphine;   Drug: naloxone;   Drug: Technetium-TC99m-labeled Annexin A5;   Procedure: forearm ischemic exercise;   Procedure: ten minute forearm ischemia

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Indicates status has not been verified in more than two years