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9 studies found for:    omecamtiv
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Rank Status Study
1 Withdrawn Pharmacokinetic Study of Omecamtiv Mecarbil in Heart Failure Patients
Condition: Heart Failure
Intervention: Drug: Omecamtiv mecarbil
2 Completed Study to Evaluate the Safety and Efficacy of IV Infusion Treatment With Omecamtiv Mecarbil in Subjects With Left Ventricular Systolic Dysfunction Hospitalized for Acute Heart Failure (ATOMIC-AHF)
Condition: Heart Failure
Interventions: Drug: Placebo;   Drug: Omecamtiv mecarbil
3 Not yet recruiting Registrational Study With Omecamtiv Mecarbil/AMG 423 to Treat Chronic Heart Failure With Reduced Ejection Fraction
Condition: Heart Failure
Interventions: Drug: Omecamtiv Mecarbil;   Drug: Placebo
4 Completed A Pharmacokinetic and Pharmacodynamic Study of Omecamtiv Mecarbil in Healthy Volunteers
Condition: Heart Failure
Interventions: Drug: placebo;   Drug: omecamtiv mecarbil
5 Recruiting Safety, PK, and Efficacy of Omecamtiv Mecarbil in Japanese Subjects With Heart Failure With Reduced Ejection Fraction
Condition: Heart Failure With Reduced Ejection Fraction
Interventions: Drug: 25 mg Omecamtiv Mecarbil;   Drug: Placebo;   Drug: 37.5 mg Omecamtiv Mecarbil;   Drug: 50 mg Omecamtiv Mecarbil
6 Completed Safety Study of Omecamtiv Mecarbil in Healthy Japanese Subjects
Condition: Heart Failure
Interventions: Drug: AMG 423;   Drug: Placebo
7 Completed COSMIC-HF - Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure.
Conditions: Modified Release Oral Formulation;   Left Ventricular Systolic Dysfunction;   Chronic Heart Failure;   History of Chronic Heart Failure;   Left Ventricular Ejection Fraction;   Pharmacokinetics;   Echocardiogram
Interventions: Drug: Omecamtiv Mecarbil;   Drug: Placebo
8 Completed Pharmacokinetics Study of AMG 423 in Healthy Subjects and Subjects With Various Degrees of Renal Insufficiency
Condition: Heart Failure
Intervention: Drug: AMG 423
9 Completed
Has Results
Pharmacokinetics of Oral CK-1827452 in Patients With Stable Heart Failure
Condition: Heart Failure
Intervention: Drug: CK-1827452

Study has passed its completion date and status has not been verified in more than two years.