23 studies found for:    niaid malaria | Open Studies
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niaid malaria | Open Studies (23 records)
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Rank Status Study
1 Recruiting Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali
Condition: Malaria
Intervention:
2 Recruiting Markers of T Cell Suppression: Antimalarial Treatment and Vaccine Responses in Healthy Malian Adults
Condition: Malaria
Intervention:
3 Recruiting Normal Immunological Parameters Among Healthy Volunteers in Kambila, Mali
Condition: Malaria
Intervention:
4 Recruiting Study of Controlled Human Malaria Infections to Evaluate Protection After Intravenous or Intramuscular Administration of PfSPZ Vaccine in Malaria-Naive Adults
Condition: Malaria
Intervention: Biological: PfSPZ Vaccine
5 Recruiting Efficacy, Safety, and Tolerability of Dihydroartemisinin-piperaquine + Mefloquine Compared to Dihydroartemisinin-piperaquine or Artesunate-mefloquine in Patients With Uncomplicated Falciparum Malaria in Cambodia
Condition: Acute Falciparum Malaria
Interventions: Drug: Dihydroartemisinin-piperaquine (DHA-PPQ);   Drug: Mefloquine (MQ)
6 Recruiting Laboratory Evaluation of Pregnancy Malaria Vaccine Candidates/In-vitro Testing of Pregnancy Malaria Vaccine Candidates
Condition: Malaria
Intervention:
7 Recruiting Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge
Condition: Malaria
Intervention:
8 Not yet recruiting Artemether-lumefantrine Resistance Monitoring in Children With Uncomplicated Plasmodium Falciparum Malaria in Mali
Condition: Accute Falciparum Malaria
Intervention:
9 Recruiting Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B...
Condition: Malaria
Interventions: Drug: Chloroquine (CQ);   Drug: Pyrimethamine (PYR);   Biological: Sanaria PfSPZ Challenge (NF54)
10 Recruiting Impact of Antimalarial Treatment on Measures of T Cell Suppression/Regulation in Healthy Adults From Doneguebougou, Mali
Condition: Malaria
Intervention:
11 Recruiting Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection
Condition: Parasitic Disease
Intervention:
12 Unknown  Malaria Transmission and Immunity in Highland Kenya
Condition: Plasmodium Falciparum Malaria
Intervention:
13 Unknown  Malaria Prevalence in Children
Condition: Plasmodium Falciparum Malaria
Intervention:
14 Unknown  Plasmodium Resistance in A. Gambiae
Conditions: Malaria;   Plasmodium Falciparum Malaria
Intervention:
15 Unknown  Time to Infection With Malaria Parasites
Condition: Plasmodium Falciparum Malaria
Intervention:
16 Unknown  Fetal Immunity to Falciparum Malaria
Condition: Plasmodium Falciparum Malaria
Intervention:
17 Not yet recruiting PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States
Condition: Plasmodium Falciparum Infection
Interventions: Drug: Chloroquine;   Biological: PfSPZ;   Other: Placebo
18 Recruiting Safety and Immunogenicity of Sanaria's Irradiated Sporozoite Vaccine (PfSPZ Vaccine) in Malaria-Experienced Adults in Burkina Faso
Condition: Plasmodium Falciparum Infection
Interventions: Drug: Artesunate;   Biological: PfSPZ;   Other: Placebo
19 Not yet recruiting PfSPZ Challenge in Non-immune Adults in Baltimore, USA
Condition: Plasmodium Falciparum Infection
Interventions: Biological: PfSPZ (NF54);   Biological: PfSPZ (7G8)
20 Recruiting Innovative Public-private Partnership to Target Subsidized Antimalarials in the Retail Sector (Aim 2)
Conditions: Fever;   Malaria
Intervention: Behavioral: Malaria RDT & conditional voucher for ACT from retail sector

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