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18 studies found for:    niaid malaria | Open Studies
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Rank Status Study
1 Recruiting Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali
Condition: Malaria
Intervention:
2 Recruiting Normal Immunological Parameters Among Healthy Volunteers in Kambila, Mali
Condition: Malaria
Intervention:
3 Recruiting Impact of Malaria on Pregnant Women in Ouelessebougou, Mali
Condition: Malaria
Intervention:
4 Recruiting Laboratory Evaluation of Pregnancy Malaria Vaccine Candidates/In-vitro Testing of Pregnancy Malaria Vaccine Candidates
Condition: Malaria
Intervention:
5 Recruiting Efficacy, Safety, and Tolerability of Dihydroartemisinin-piperaquine + Mefloquine Compared to Dihydroartemisinin-piperaquine or Artesunate-mefloquine in Patients With Uncomplicated Falciparum Malaria in Cambodia
Condition: Acute Falciparum Malaria
Interventions: Drug: Dihydroartemisinin-piperaquine (DHA-PPQ);   Drug: Mefloquine (MQ)
6 Recruiting Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge
Condition: Malaria
Intervention:
7 Recruiting Artemether-lumefantrine Resistance Monitoring in Children With Uncomplicated Plasmodium Falciparum Malaria in Mali
Condition: Accute Falciparum Malaria
Intervention:
8 Recruiting Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Trial to Determine Safety and Development of Protective Efficacy After Exposure to Only Pre-erythrocytic Stages of Plasmodium Falciparum
Condition: Malaria
Interventions: Drug: Chloroquine Phosphate;   Drug: Pyrimethamine;   Biological: Sanaria PfSPZ Challenge
9 Recruiting Safety and Immunogenicity of Pfs25M-EPA/AS01 and Pfs230D1M-EPA/AS01 Vaccines, Transmission Blocking Vaccines Against Plasmodium Falciparum, at Full and Fractional Dosing in Adults in Mali
Condition: Malaria
Interventions: Biological: Pfs25M-EPA/AS01;   Biological: Pfs230D1M-EPA/AS01;   Other: AS01;   Biological: Bexsero (Comparator Vaccine);   Biological: Fluarix;   Other: Normal Saline;   Drug: Coartem
10 Not yet recruiting Impact of Antimalarial Treatment on Measures of T Cell Suppression/Regulation in Healthy Adults From Doneguebougou, Mali
Condition: Malaria
Intervention:
11 Not yet recruiting A Systems Biology Approach to Malaria Immunity
Condition: Plasmodium Falciparum Infection
Intervention: Biological: NF54 P. falciparum malaria challenge
12 Recruiting PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States
Condition: Plasmodium Falciparum Infection
Interventions: Drug: Chloroquine;   Biological: PfSPZ;   Other: Placebo
13 Recruiting Safety and Immunogenicity of Sanaria's Irradiated Sporozoite Vaccine (PfSPZ Vaccine) in Malaria-Experienced Adults in Burkina Faso
Condition: Plasmodium Falciparum Infection
Interventions: Drug: Artesunate;   Biological: PfSPZ;   Other: Placebo
14 Not yet recruiting PfSPZ Challenge With Prophylaxis in Mali
Condition: Plasmodium Falciparum Infection
Interventions: Drug: Artesunate;   Drug: Chloroquine;   Biological: PfSPZ (NF54);   Other: Placebo
15 Recruiting Innovative Public-private Partnership to Target Subsidized Antimalarials in the Retail Sector (Aim 2)
Conditions: Fever;   Malaria
Intervention: Behavioral: Malaria RDT & conditional voucher for ACT from retail sector
16 Recruiting Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection
Condition: Parasitic Disease
Intervention:
17 Recruiting Randomized, Double-Blind, Placebo-Controlled, Phase 1 Study in Healthy Volunteers to Evaluate the Safety and Immunogenicity of AGS-v, a Universal Mosquito-Borne Disease Vaccine
Condition: Mosquito-Borne Disease
Interventions: Biological: AGS-v;   Biological: AGS-v + adjuvant;   Other: Placebo
18 Not yet recruiting PrEP Implementation for Mothers in Antenatal Care
Conditions: HIV Infections;   Pregnancy Related
Interventions: Drug: Universal PrEP Counseling;   Drug: Targeted PrEP Counseling

Study has passed its completion date and status has not been verified in more than two years.