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34 studies found for:    necrotizing enterocolitis | NIH
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Rank Status Study
1 Completed Comparison of Two Surgical Treatments for Necrotizing Enterocolitis in Human Infants
Condition: Necrotizing Enterocolitis
Interventions: Procedure: laparotomy;   Procedure: primary peritoneal drainage
2 Completed Role of Epidermal Growth Factor (EGF) in Development of Necrotizing Enterocolitis
Conditions: Necrotizing Enterocolitis;   Premature Birth
Intervention:
3 Completed Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants
Conditions: Necrotizing Enterocolitis;   Sepsis
Interventions: Behavioral: Fortified Pasteurized Donor Human Milk supplement;   Behavioral: Preterm Formula supplement
4 Recruiting Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Enterocolitis, Necrotizing;   Intestinal Perforation
Interventions: Procedure: Laparotomy;   Procedure: Drainage
5 Completed Effect of Vitamin A in the Treatment of Neonatal Sepsis and Necrotizing Enterocolitis
Conditions: Sepsis;   Necrotizing Enterocolitis;   Meningitis;   Pneumonia
Intervention: Dietary Supplement: Vitamin A
6 Completed
Has Results
Metronidazole Pharmacokinetics (PK) in Premature Infants
Conditions: Serious Systemic Infections;   Necrotizing Enterocolitis
Intervention: Drug: Metronidazole
7 Recruiting RBC Irradiation, Anemia and Gut Injury
Conditions: Anemia;   Necrotizing Enterocolitis
Intervention: Device: Near Infrared Spectroscopy
8 Completed Effects of Delayed Cord Clamping in Very Low Birth Weight Infants
Conditions: Bronchopulmonary Dysplasia;   Necrotizing Enterocolitis;   Intraventricular Hemorrhage;   Late Onset Neonatal Sepsis;   Motor Skills Disorders
Intervention: Procedure: delayed cord clamping
9 Completed Observational Study of Surgical Treatment of Necrotizing Enterocolotis
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Enterocolitis, Necrotizing;   Intestinal Perforation
Intervention:
10 Completed
Has Results
Pharmacokinetic (PK) and Safety Study of Meropenem in Young Infants With Intra-abdominal Infections
Conditions: Necrotizing Enterocolitis;   Intra-abdominal Infection
Intervention: Drug: meropenem
11 Completed Brain Manganese Deposition in High Risk Neonates
Conditions: Necrotizing Enterocolitis;   Digestive System Abnormalities;   Cholestasis
Intervention: Dietary Supplement: remove Mn from PN if evidence of increased brain Mn on MRI
12 Completed Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP)
Conditions: Infant, Very Low Birth Weight;   Infant, Premature;   Ductus Arteriosus, Patent
Interventions: Drug: indomethacin;   Drug: Indomethacin;   Drug: Placebo
13 Active, not recruiting
Has Results
Surfactant Positive Airway Pressure and Pulse Oximetry Trial
Conditions: Infant, Newborn, Diseases;   Other Preterm Infants;   Infant, Small for Gestational Age;   Premature Birth;   Bronchopulmonary Dysplasia;   Retinopathy of Prematurity
Interventions: Drug: Surfactant;   Device: Continuous Positive Airway Pressure (CPAP);   Drug: Supplemental oxygen with target saturation of 85 to 89%;   Drug: Supplemental oxygen with target saturation of 91 to 95%
14 Completed Safety and Efficacy of Intranasal and Topical Mupirocin in Eradicating Colonization With Staphylococcus Aureus (SA) in Critically Ill Infants - a Phase 2, Multi-Center, Open Label, Randomized Trial
Condition: Staphylococcal Infection
Intervention: Drug: Mupirocin calcium
15 Completed
Has Results
MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine
Conditions: Apnea of Prematurity;   Intraventricular Hemorrhage;   Brain Injury
Intervention: Drug: Caffeine citrate
16 Active, not recruiting Hydrocortisone for Term Hypotension
Conditions: Infant, Newborn, Diseases;   Cardiovascular Insufficiency
Interventions: Drug: Hydrocortisone;   Drug: Placebo
17 Completed Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial
Conditions: Pregnancy;   Respiratory Distress;   Pregnancy Outcome
Intervention: Drug: Corticosteroid
18 Completed
Has Results
Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants Less Than 750 Grams Birthweight
Condition: Candidiasis
Interventions: Drug: fluconazole;   Drug: placebo
19 Recruiting Transfusion of Prematures Trial
Conditions: Infant, Newborn, Diseases;   Infant, Extremely Low Birth Weight;   Infant, Small for Gestational Age;   Bronchopulmonary Dysplasia (BPD);   Anemia
Interventions: Procedure: Liberal Cell Transfusion;   Procedure: Restricted red cell transfusion
20 Completed
Has Results
PREGNANT Short Cervix Trial
Conditions: Preterm Delivery;   Short Cervix;   Short Uterine Cervical Length
Interventions: Drug: progesterone;   Drug: placebo

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