16 studies found for:    necrotizing enterocolitis | NICHD [Lead]
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necrotizing enterocolitis | NICHD [Lead] (16 records)
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Rank Status Study
1 Recruiting Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Enterocolitis, Necrotizing;   Intestinal Perforation
Interventions: Procedure: Laparotomy;   Procedure: Drainage
2 Completed Observational Study of Surgical Treatment of Necrotizing Enterocolotis
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Enterocolitis, Necrotizing;   Intestinal Perforation
Intervention:
3 Completed Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP)
Conditions: Infant, Very Low Birth Weight;   Infant, Premature;   Ductus Arteriosus, Patent
Interventions: Drug: indomethacin;   Drug: Indomethacin;   Drug: Placebo
4 Completed
Has Results
Pharmacokinetic (PK) and Safety Study of Meropenem in Young Infants With Intra-abdominal Infections
Conditions: Necrotizing Enterocolitis;   Intra-abdominal Infection
Intervention: Drug: meropenem
5 Active, not recruiting
Has Results
Surfactant Positive Airway Pressure and Pulse Oximetry Trial
Conditions: Infant, Newborn, Diseases;   Other Preterm Infants;   Infant, Small for Gestational Age;   Premature Birth;   Bronchopulmonary Dysplasia;   Retinopathy of Prematurity
Interventions: Drug: Surfactant;   Device: Continuous Positive Airway Pressure (CPAP);   Drug: Supplemental oxygen with target saturation of 85 to 89%;   Drug: Supplemental oxygen with target saturation of 91 to 95%
6 Active, not recruiting Hydrocortisone for Term Hypotension
Conditions: Infant, Newborn, Diseases;   Cardiovascular Insufficiency
Interventions: Drug: Hydrocortisone;   Drug: Placebo
7 Completed Intravenous Immune Globulin (IVIG) to Prevent Neonatal Infection
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Sepsis
Interventions: Drug: IVIG;   Drug: Placebo
8 Terminated Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (SAVE)
Conditions: Bronchopulmonary Dysplasia;   Respiratory Distress Syndrome;   Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature
Interventions: Procedure: Minimal mechanical ventilation management;   Procedure: Routine mechanical ventilation management;   Drug: Dexamethasone;   Drug: Placebo
9 Completed Glutamine Supplementation to Prevent Death or Infection in Extremely Premature Infants
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Sepsis
Interventions: Drug: Glutamine;   Drug: Placebo
10 Completed Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight
Conditions: Hyperbilirubinemia, Neonatal;   Jaundice, Neonatal;   Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature
Interventions: Procedure: Aggressive Phototherapy 501-750g;   Procedure: Aggressive Phototherapy 751-1000g;   Procedure: Conservative Phototherapy 501-750g;   Procedure: Conservative Phototherapy 751-1000g
11 Recruiting Transfusion of Prematures Trial
Conditions: Infant, Newborn, Diseases;   Infant, Extremely Low Birth Weight;   Infant, Small for Gestational Age;   Bronchopulmonary Dysplasia (BPD);   Anemia
Interventions: Procedure: Liberal Cell Transfusion;   Procedure: Restricted red cell transfusion
12 Completed Growth Observational Study
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature
Intervention:
13 Completed Omega-3 Fatty Acid Supplementation to Prevent Preterm Birth in High Risk Pregnancies
Condition: Preterm Birth
Intervention: Drug: 17 alpha-Hydroxyprogesterone Caproate and Omega-3 fish oils
14 Completed Inflammatory Cytokines Associated With Perinatal Brain Injury
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Cerebral Palsy
Intervention:
15 Completed Early Blood Pressure Management in Extremely Premature Infants
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Hypotension;   Blood Pressure
Interventions: Drug: Dopamine;   Drug: Hydrocortisone;   Drug: Infusion Placebo;   Drug: Syringe Placebo
16 Recruiting Establishment of a Perinatal Database and a Bank of Biological Materials
Conditions: Preterm Labor;   Preterm Birth;   Pregnancy
Intervention:

Indicates status has not been verified in more than two years