| 1 |
NCT00735384 |
Recruiting |
Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies |
|
|
Observational
|
|
- University Hospital, Basel, Switzerland
- University of Minnesota - Clinical and Translational Science Institute
|
Other |
- Observational Model: Case-Control
- Time Perspective: Prospective
|
- Skeletal Muscle Force in ICU Patients and Patients with Primary Myopathies
- Muscle forces pending on the Malignant Hyperthermia (MH) status of a patient (susceptible to MH or not susceptible to MH)
|
80 |
All |
18 Years and older (Adult, Older Adult) |
NCT00735384 |
134/02
P21/08//A05/08 |
|
September 2006 |
December 2018 |
December 2018 |
August 14, 2008 |
January 16, 2018 |
|
- University of Basel Hospital
Basel, Switzerland
|
|
| 2 |
NCT01166854 |
Recruiting |
Characterization of Familial Myopathy and Paget Disease of Bone |
- Muscle Disorder
- Bone Disorder
|
- Device: Diffuse Optical Spectroscopy
|
Observational
|
|
- University of California, Irvine
- Beckman Laser Institute University of California Irvine
|
Other |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
|
25 |
All |
18 Years and older (Adult, Older Adult) |
NCT01166854 |
NIH/LAMMP-2007-5832 |
|
June 2010 |
June 2018 |
June 2018 |
July 21, 2010 |
February 13, 2018 |
|
- Beckman Laser Institute Medical clinic
Irvine, California, United States
|
|
| 3 |
NCT01417533 |
Recruiting |
A Natural History Study of Patients With GNE Myopathy |
- Hereditary Inclusion Body Myopathy
|
|
Observational
|
|
- National Human Genome Research Institute (NHGRI)
- Therapeutics for Rare and Neglected Diseases (TRND)
- National Institutes of Health Clinical Center (CC)
|
NIH |
- Time Perspective: Prospective
|
- The baseline rate of progression of complications and its correlation with age of onset of the disease.
- The functional outcome measures (potential endpoints) to be used to test future therapeutic interventions.
- The identification of potential serum biomarkers (sialylated as disease markers and the correlation between muscle magnetic resonance imaging (MRI) findings with progression of the disease
- The rates of progression for individual subjects.
|
100 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT01417533 |
110218
11-HG-0218 |
|
August 13, 2011 |
|
|
August 16, 2011 |
January 18, 2019 |
|
- National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States
|
|
| 4 |
NCT03751644 |
Recruiting |
Peripherical Neuromuscular Electrical Stimulation in Systemic Autoimmune Myopathies |
- Electrical Remodeling
- Rheumatic Diseases
- Myopathy
|
- Other: Electrical stimulation
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Other
|
- Frequency of treatment-emergent adverse events [safety and tolerability]
- Healthy Assessment Questionnaire (HAQ)
- Patient/Parent Global Activity
- (and 5 more...)
|
40 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT03751644 |
MYO-HCFMUSP-07 |
|
November 1, 2018 |
November 1, 2021 |
November 1, 2023 |
November 22, 2018 |
November 22, 2018 |
|
- Samuel K Shinjo
Sao Paulo, Brazil
|
|
| 5 |
NCT03693898 |
Recruiting |
MR in Patients With Collagen VI Related Myopathies |
- Bethlem Myopathy
- Ullrich Disease
|
|
Interventional
|
Not Applicable |
- Ruth Salim
- Rigshospitalet, Denmark
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Muscle fat fraction
- Muscle strength
|
20 |
All |
18 Years and older (Adult, Older Adult) |
NCT03693898 |
H-18023049 |
|
September 1, 2018 |
May 1, 2019 |
May 1, 2019 |
October 3, 2018 |
October 10, 2018 |
|
- Copenhagen Neuromuscular Center
Copenhagen, Østerbro, Denmark
|
|
| 6 |
NCT03673761 |
Recruiting |
Muscle in Acromegaly and Cushing's Syndrome |
- Cushing Syndrome
- Acromegaly
|
- Other: MRI, dual-energy, x-ray absorptiometry, muscle ultrasounds, blood testing
|
Observational
|
|
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
|
Other |
- Observational Model: Case-Control
- Time Perspective: Cross-Sectional
|
- MRI assessment of fatty infiltration in tigh muscles.
- microRNAs
|
120 |
Female |
18 Years to 65 Years (Adult, Older Adult) |
NCT03673761 |
IIBSP-MIO-2017-41 |
MAC |
February 1, 2018 |
October 31, 2018 |
January 31, 2019 |
September 17, 2018 |
September 17, 2018 |
|
- Hospital de la Santa Creu i Sant Pau
Barcelona, Please Select, Spain
|
|
| 7 |
NCT03083652 |
Recruiting |
Effects of Neuromuscular Electrical Stimulation on Exercise Capacity in Respiratory Critically Ill Patients |
- Critical Illness Myopathy
|
- Device: Neuromuscular electrical stimulation
- Other: Sham
|
Interventional
|
Not Applicable |
- Hospital Clinic of Barcelona
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Supportive Care
|
- Exercise capacity
- Muscle strength
- Body composition (fat free mass)
- Functional Capacity
|
40 |
All |
18 Years and older (Adult, Older Adult) |
NCT03083652 |
UVIR |
|
February 1, 2017 |
March 1, 2019 |
July 1, 2019 |
March 20, 2017 |
August 20, 2018 |
|
- Unidad de Vigilancia Intensiva Respiratoria (UVIR)
Barcelona, Spain
|
|
| 8 |
NCT03717831 |
Recruiting |
Muscle Dysfunction in Critical Illness |
- Critical Illness
- Intensive Care (ICU) Myopathy
- PICS
- Muscle Weakness
|
|
Observational
|
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Physical function
- Capacity for physical activity/exercise
|
120 |
All |
18 Years and older (Adult, Older Adult) |
NCT03717831 |
46072-58919 |
|
October 17, 2018 |
October 2019 |
October 2019 |
October 24, 2018 |
October 25, 2018 |
|
- University of Kentucky
Lexington, Kentucky, United States
|
|
| 9 |
NCT03660969 |
Recruiting |
Reliability of Cardiac Troponins for the Diagnosis of Myocardial Infarction in the Presence of Skeletal Muscle Disease |
- Myopathy
- Muscle Weakness
- Muscle Damage
- (and 5 more...)
|
|
Observational
|
|
- Christian Müller, MD
- Cantonal Hospital of Aarau, Switzerland
- Medical University Innsbruck
- University Hospital, Basel, Switzerland
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Comparison of cTnT and cTnI levels as measured by different hs-cTn assays in patients with skeletal muscle disease.
- Comparison of levels of cTnT and cTnI as measured by hs-assays in matched patients with and without skeletal muscle disease.
- Regression model of diverse patients' characteristics on levels of hs-cTnI and hs-cTnT in the context of skeletal muscle disease versus no skeletal muscle disease.
- (and 3 more...)
|
200 |
All |
18 Years and older (Adult, Older Adult) |
NCT03660969 |
BASEL XII
Research Grant |
H&M |
January 1, 2018 |
January 1, 2021 |
January 1, 2023 |
September 7, 2018 |
November 14, 2018 |
|
- Medical University Innsbruck
Innsbruck, Austria - Canton Hospital of Aarau
Aarau, Aargau, Switzerland - University Hospital Basel
Basel, Switzerland
|
|
| 10 |
NCT01171573 |
Recruiting |
Investigating Genes in Patients With Polymyositis and Dermatomyositis |
|
|
Observational
|
|
- Salford Royal NHS Foundation Trust
|
Other |
- Observational Model: Case-Control
- Time Perspective: Prospective
|
- To identify any disease susceptibility genes associated with development and clinical characteristics of primary inflammatory muscle diseases, PM, DM and IBM.
|
1000 |
All |
18 Years to 70 Years (Adult, Older Adult) |
NCT01171573 |
Ollier-002 |
UKMYONET |
January 2001 |
January 2020 |
January 2020 |
July 28, 2010 |
December 4, 2018 |
|
- Salford Royal NHS Foundation Trust
Manchester, United Kingdom
|
|
| 11 |
NCT03600454 |
Not yet recruiting |
The Effect of Anesthesia on Perioperative Muscle Weakness and Neuro-endocrine Stress Response |
- Muscle Weakness
- Anesthesia
- Anesthesia, Local
- Surgery
|
- Drug: General anesthesia
- Drug: Spinal anesthesia
- Drug: General anesthesia and epidural analgesia
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Basic Science
|
- Change in post-operative peripheral limb muscle weakness
- Change in general health status
- Change in post-operative lung function: vital capacity
- (and 5 more...)
|
100 |
All |
18 Years and older (Adult, Older Adult) |
NCT03600454 |
18/0010U |
MUSCLE |
September 1, 2018 |
June 30, 2019 |
September 30, 2019 |
July 25, 2018 |
July 25, 2018 |
|
|
|
| 12 |
NCT03496389 |
Not yet recruiting |
Does Gabapentin Reduce Quadriceps Muscle Weakness After Anterior Cruciate Ligament Reconstruction? |
- Muscle Weakness
- Anterior Cruciate Ligament Rupture
|
- Drug: Gabapentin
- Drug: Tramadol
- Drug: Panadol
|
Interventional
|
Phase 2
Phase 3 |
- Hospital Authority, Hong Kong
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change in from baseline quadriceps muscle strength
- Anterior-posterior knee stability
- Rotational laxity
- Functional outcome
|
30 |
All |
18 Years to 50 Years (Adult) |
NCT03496389 |
Gabapentin ACLR |
|
July 1, 2018 |
July 1, 2019 |
August 1, 2019 |
April 12, 2018 |
April 12, 2018 |
|
|
|
| 13 |
NCT03270163 |
Recruiting |
Evaluation of Muscle Strength by Transcutaneous Electrical Stimulation |
|
- Diagnostic Test: Transcutaneous electrical stimulation
|
Interventional
|
Not Applicable |
- Centre Hospitalier Universitaire de Saint Etienne
- Laboratoire de Physiologie de l’Exercice
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Reproducibility
- Intensive care unit acquired muscle weakness (ICUAW)
|
15 |
All |
18 Years to 90 Years (Adult, Older Adult) |
NCT03270163 |
1708055
2017-A00919-44 |
STRENGHT-ICU |
November 2018 |
November 2018 |
November 2018 |
September 1, 2017 |
October 22, 2018 |
|
- Chu Saint-Etienne
Saint-etienne, France
|
|
| 14 |
NCT02893228 |
Recruiting |
Does Saline Injection Around Phrenic Nerve Reduce Incidence of Diaphragmatic Paresis Following Interscalene Block? |
|
- Procedure: Saline
- Drug: Levobupivacaine
|
Interventional
|
Phase 4 |
- The Adelaide and Meath Hospital, incorporating The National Children's Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Outcomes Assessor)
- Primary Purpose: Supportive Care
|
- Rate of diaphragmatic paresis recorded in the post-operative period identified by ultrasound assessment
- FEV1
- FVC
- (and 2 more...)
|
36 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT02893228 |
AMNCH-A-SIPPIB |
|
October 2016 |
September 2018 |
November 2018 |
September 8, 2016 |
January 12, 2018 |
|
- Adelaide and Meath Hospital, Incorporating National Children Hospital
Tallagh, Dublin 24, Ireland
|
|
| 15 |
NCT02746718 |
Recruiting |
Frequency of Pompe's Disease and Neuromuscular Etiologies in Patients With Restrictive Respiratory Failure Associated With Signs of Muscle Weakness |
|
|
Interventional
|
Not Applicable |
- Centre Hospitalier Universitaire de Nice
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Number of new cases of Pompe disease diagnosed by a positive DBS
- Number of new cases and etiologies of neuromuscular diseases diagnosed in patients with unexplained restriction of lung volumes
- Frequency and description of neurological symptoms associated with neuromuscular diseases to respiratory revelation
|
500 |
All |
18 Years and older (Adult, Older Adult) |
NCT02746718 |
14-PP-13 |
POPS3 |
December 11, 2015 |
December 11, 2019 |
December 11, 2019 |
April 21, 2016 |
March 19, 2018 |
|
- CHU d'Angers
Angers, France - Centre hospitalier d'Argenteuil
Argenteuil, France - CHU de Brest
Brest, France - (and 18 more...)
|
|
| 16 |
NCT03669588 |
Recruiting |
An Efficacy and Safety Study of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness |
- Generalized Myasthenia Gravis
|
- Biological: ARGX-113
- Biological: Placebo
|
Interventional
|
Phase 3 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Efficacy of ARGX-113 as assessed by the percentage of "Myasthenia Gravis Activities of Daily Living (MG-ADL) responders" in the acetylcholine receptor (AChR)-antibody (Ab) seropositive population
- Efficacy of ARGX-113 as assessed by the percentage of "Quantitative Myasthenia Gravis (QMG) responders" in the AChR-Ab seropositive population.
- Efficacy of ARGX-113 as assessed by the percentage of "MG-ADL responders" in the overall population (AChR-Ab seropositive and AChR-Ab seronegative patients).
- (and 3 more...)
|
150 |
All |
18 Years and older (Adult, Older Adult) |
NCT03669588 |
ARGX-113-1704
2018-002132-25 |
ADAPT |
September 5, 2018 |
June 2020 |
November 2020 |
September 13, 2018 |
December 25, 2018 |
|
- Investigator Site 4
Tampa, Florida, United States - Investigator Site 3
Chapel Hill, North Carolina, United States - Investigator Site
Cordova, Tennessee, United States - Investigator Site 2
Charlottesville, Virginia, United States
|
|
| 17 |
NCT03770403 |
Not yet recruiting |
A Safety and Tolerability Study of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness. |
- Generalized Myasthenia Gravis
|
|
Interventional
|
Phase 3 |
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Safety and Tolerability as measured by the incidence of treatment emergent (serious) adverse events in the AChR-positive population.
- Safety and Tolerability as measured by the incidence of treatment emergent (serious) adverse events in the overall population (AChR-Ab seropositive patients and AChR-Ab seronegative patients).
- Safety and Tolerability as measured by the incidence of treatment emergent (serious) adverse events after each treatment period in the AChR-Ab seropositive patients.
- Safety and Tolerability as measured by the incidence of treatment emergent (serious) adverse events after each treatment period in the overall population (AChR-Ab seropositive patients and AChR-Ab seronegative patients).
|
150 |
All |
18 Years and older (Adult, Older Adult) |
NCT03770403 |
ARGX-113-1705
2018-002133-37 |
ADAPT+ |
January 2, 2019 |
June 2021 |
June 2021 |
December 10, 2018 |
December 10, 2018 |
|
- Investigator Site
Cordova, Tennessee, United States
|
|
| 18 |
NCT03526211 |
Recruiting |
Safety Evaluation of Functional Electrical Stimulation (FES) Cycling in Intensive Care Unit Patients |
|
|
Interventional
|
Not Applicable |
- Centre Hospitalier Universitaire de Saint Etienne
- Laboratoire de Physique ENS de Lyon
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Other
|
- Tolerance
- Systolic blood pressure
- Haemodynamic tolerance Heart rate
- (and 17 more...)
|
20 |
All |
18 Years and older (Adult, Older Adult) |
NCT03526211 |
18CH005
2018-A00541-54 |
FES Cycling |
July 24, 2018 |
May 31, 2020 |
June 7, 2020 |
May 16, 2018 |
December 13, 2018 |
|
- BURNOL Laetitia
Saint-etienne, France
|
|
| 19 |
NCT00082108 |
Recruiting |
Myotonic Dystrophy and Facioscapulohumeral Muscular Dystrophy Registry |
- Myotonic Dystrophy
- Facioscapulohumeral Muscular Dystrophy
- Muscular Dystrophy
- (and 6 more...)
|
|
Observational
|
|
- University of Rochester
- National Institute of Neurological Disorders and Stroke (NINDS)
|
Other / NIH |
- Observational Model: Other
- Time Perspective: Prospective
|
- Patient reported outcomes
|
3000 |
All |
Child, Adult, Older Adult |
NCT00082108 |
NIAMS-104
U54NS048843 |
|
September 2000 |
June 2023 |
June 2023 |
April 30, 2004 |
October 4, 2018 |
|
- University of Rochester Medical Center, Department of Neurology
Rochester, New York, United States
|
|
| 20 |
NCT03581760 |
Recruiting |
Cycling Exercise in Mechanical Ventilation |
- Muscle Weakness
- Mechanical Ventilation Complication
|
- Other: Cycling Exercise
- Other: Conventional Physiotherapy
|
Interventional
|
Not Applicable |
- University Hospital Ostrava
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Number of ventilator days
- Muscle strength
|
120 |
All |
18 Years and older (Adult, Older Adult) |
NCT03581760 |
KARIM-08-Motomed
MH CZ - DRO-FNOs/2017 |
|
May 2, 2017 |
November 2020 |
December 2020 |
July 10, 2018 |
July 10, 2018 |
|
- University Hospital Ostrava
Ostrava, Moravian-Silesian Region, Czechia
|
|
| 21 |
NCT03573479 |
Not yet recruiting |
Early Rehabilitation in Critically Ill Children - The PICU Liber8 Study |
- Delirium
- Withdrawal Syndrome
- Hospital Acquired Condition
- (and 2 more...)
|
- Other: PICU Liber8 Bundle
|
Observational
|
|
- McMaster University
- London Health Sciences Centre
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Completion rate of daily goals (compliance)
- Performance of the bundle assessed with qualitative (i.e., narrative) description and comparison between groups.
- Perceptions about barriers and facilitators for implementation of the bundle
- (and 9 more...)
|
160 |
All |
1 Month to 18 Years (Child, Adult) |
NCT03573479 |
PICULiber8/180409 |
PICULiber8 |
October 2018 |
October 2019 |
October 2020 |
June 29, 2018 |
June 29, 2018 |
|
- McMaster Children's Hospital
Hamilton, Ontario, Canada - Children's Hospital London Health Sciences
London, Ontario, Canada
|
|
| 22 |
NCT01933841 |
Recruiting |
The Impact of Quantitative Neuromuscular Monitoring in the PACU on Residual Blockade and Postoperative Recovery |
|
- Device: TOF-Watch SX
- Procedure: Notify the provider
|
Observational
|
|
- Vanderbilt University Medical Center
|
Other |
- Observational Model: Case-Control
- Time Perspective: Prospective
|
- Decrease in incidence of postoperative residual curarization
- Decrease in the incidence of hemoglobin desaturation
- Decrease in need for reintubation
- (and 3 more...)
|
400 |
All |
18 Years and older (Adult, Older Adult) |
NCT01933841 |
131282 |
|
August 2013 |
September 2019 |
September 2019 |
September 2, 2013 |
August 21, 2018 |
|
- Vanderbilt University Medical Center
Nashville, Tennessee, United States
|
|
| 23 |
NCT03735693 |
Recruiting |
Diagnosis of Muscular Weakness Syndrome After a Stay in Intensive Care : Measurement by Ultrasound |
- Amyotrophia
- Weakness, Muscle
|
- Diagnostic Test: Ulstrasound
|
Observational
|
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Determination of the day of ultrasound examination having the highest diagnostic performance to predict with a maximum of specificity the occurrence of a neuromuscular weakness syndrome post-intensive care unit
- Determination of the perfect threshold of muscular decrease allowing the prediction with the maximum of specificity of a post-intensive care neuromuscular weakness syndrome
- comparison of the persistence of neuromuscular weakness into 2 cohorts of patients (probably not affected by the syndrome, and probably affected)
- (and 7 more...)
|
80 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT03735693 |
3-2018-FIBER |
FIBER |
September 14, 2018 |
December 14, 2020 |
September 14, 2021 |
November 8, 2018 |
November 8, 2018 |
|
- CHU Grenoble Alpes
Grenoble, France
|
|
| 24 |
NCT03359473 |
Recruiting |
Study to Evaluate the Safety and Efficacy of 13 Weeks of the Selective Androgen Receptor Modulator (SARM) GSK2881078 in Chronic Obstructive Pulmonary Disease (COPD) |
|
- Drug: GSK2881078
- Drug: Matching Placebo
|
Interventional
|
Phase 2 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change in blood pressure from Baseline
- Change in heart rate from Baseline
- Change in electrocardiogram (ECG) from Baseline
- (and 25 more...)
|
100 |
All |
50 Years to 75 Years (Adult, Older Adult) |
NCT03359473 |
200182 |
|
February 28, 2018 |
November 3, 2019 |
November 3, 2019 |
December 2, 2017 |
August 24, 2018 |
|
- GSK Investigational Site
Torrance, California, United States - GSK Investigational Site
Jacksonville, Florida, United States - GSK Investigational Site
High Point, North Carolina, United States - (and 3 more...)
|
|
| 25 |
NCT03666013 |
Recruiting |
Mitochondria and Muscle Health in Elderly |
|
|
Observational
|
|
- Maastricht University
- Netherlands Organisation for Scientific Research
- Top Institute Food and Nutrition
|
Other |
- Observational Model: Other
- Time Perspective: Cross-Sectional
|
- Rate of ex vivo mitochondrial State 3 respiration
- Insuline sensitivity
- Physical functionality, 6MWT
- (and 8 more...)
|
68 |
All |
65 Years to 80 Years (Older Adult) |
NCT03666013 |
Mitohealth |
ELMIH |
June 27, 2017 |
October 1, 2019 |
October 1, 2019 |
September 11, 2018 |
September 11, 2018 |
|
- Maastricht University
Maastricht, Limburg, Netherlands
|
|
| 26 |
NCT02847988 |
Recruiting |
Facilitating Functional Independence in Patients Receiving Prolonged Mechanical Ventilation |
|
- Device: Neuromuscular electrical Stimulation (NMES)
- Device: Sham Stimulation
|
Interventional
|
Not Applicable |
- RML Specialty Hospital
- National Institute of Nursing Research (NINR)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Time to reach independence in performing functional activity
- The percentage of patients who can perform functional activities independently
|
200 |
All |
18 Years and older (Adult, Older Adult) |
NCT02847988 |
AXJ014
R01NR016055 |
|
July 2016 |
June 2021 |
February 2022 |
July 28, 2016 |
May 2, 2017 |
|
- RML Specialty Hospital
Hinsdale, Illinois, United States
|
|
| 27 |
NCT02873559 |
Recruiting |
Effect of PROGRESSive Training and Teststerone in Older Frail Men |
|
- Drug: testosterone
- Other: Progressive muscle training
|
Interventional
|
Phase 2
Phase 3 |
- University Hospital, Gentofte, Copenhagen
|
Other |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Stand-up-and Sit-test
- Frequency and severity of falls via questionaire
- Balance ability,
- (and 33 more...)
|
196 |
Male |
70 Years and older (Older Adult) |
NCT02873559 |
Ethical protocol H-16020521 |
PROGRESS |
November 2016 |
August 2018 |
January 2019 |
August 19, 2016 |
August 29, 2017 |
|
- Karsten Overgaard
Hellerup, Danmark, Denmark - Medical Dept. O, Geriatric Section
Herlev, Denmark
|
|
| 28 |
NCT03543826 |
Recruiting |
Best Practice Using Rocuronium and Reversal With Neostigmine or Sugammadex |
|
- Other: Protocol for rocuronium neuromuscular block
|
Interventional
|
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Incidence of postoperative residual neuromuscular blockade at time of arrival to the post-anesthesia care unit.
- Incidence of postoperative severe residual neuromuscular blockade at time of arrival to the post-anesthesia care unit.
- Incidence of postoperative residual neuromuscular blockade at time of tracheal extubation.
|
120 |
All |
18 Years and older (Adult, Older Adult) |
NCT03543826 |
STUDY00003888 |
|
May 21, 2018 |
November 20, 2018 |
November 20, 2018 |
June 1, 2018 |
June 14, 2018 |
|
- University of Washington Medical Center
Seattle, Washington, United States
|
|
| 29 |
NCT03301116 |
Recruiting |
Promoting Seniors' Health With Home Care Aides |
|
- Behavioral: Healthy Moves for Aging Well (Healthy Moves)
- Behavioral: Active Mind for Aging Well (Active Mind)
|
Interventional
|
Phase 2 |
- University of Illinois at Chicago
- National Institute on Aging (NIA)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Change from Baseline Function (Daily activity difficulties and dependency in older home care clients) at Month 4
- Short Physical Performance Battery (SPPB)
- Exercise-related social support from home care aides
- (and 3 more...)
|
300 |
All |
60 Years to 110 Years (Adult, Older Adult) |
NCT03301116 |
2016-0689
R01AG053675 |
|
September 1, 2017 |
May 31, 2020 |
April 30, 2021 |
October 4, 2017 |
October 18, 2018 |
|
- University of Illinois at Chicago
Chicago, Illinois, United States
|
|
| 30 |
NCT03240640 |
Recruiting |
Effects of Inspiratory Muscle Training on Shortness of Breath (Dyspnea) and Postural Control in Patients With COPD |
- Copd
- Inspiratory Muscle Weakness
|
- Procedure: Inspiratory Muscle Strength Training
- Procedure: Inspiratory Muscle Endurance Training
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Dyspnea (Borg CR-10 scale)
- Center of pressure displacement
- Maximal inspiratory pressure (Pi,max)
- (and 15 more...)
|
24 |
All |
40 Years to 90 Years (Adult, Older Adult) |
NCT03240640 |
S58513 |
|
February 1, 2017 |
December 31, 2017 |
January 31, 2018 |
August 7, 2017 |
August 8, 2017 |
|
- University Hospital Leuven
Leuven, Belgium
|
|
| 31 |
NCT01270516 |
Recruiting |
Effect of EPA and HMB on Strength in ICU Patients |
|
- Drug: HMB, hydroxymethylbutyrate
- Drug: EPA, eicosapentaenoic acid
- Drug: Saline
|
Interventional
|
Not Applicable |
- Gerald Supinski
- University of Kentucky
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Improvement of skeletal muscle strength for one of the drugs compared to placebo
- duration of mechanical ventilation
|
80 |
All |
18 Years and older (Adult, Older Adult) |
NCT01270516 |
Diaphragm EPA HMB |
|
January 2014 |
December 30, 2018 |
December 30, 2018 |
January 5, 2011 |
October 15, 2018 |
|
- Chandler Hospital
Lexington, Kentucky, United States
|
|
| 32 |
NCT02508311 |
Recruiting |
Albuterol to Improve Respiratory Strength in SCI |
- Spinal Cord Injury
- Respiratory Muscle Weakness
|
- Drug: Oral Albuterol Extended Release
- Drug: Placebo
|
Interventional
|
Not Applicable |
- VA Office of Research and Development
|
U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change in Respiratory Muscle Strength
|
24 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT02508311 |
B1910-P
SCH-15-011 |
|
June 1, 2016 |
March 1, 2019 |
June 28, 2019 |
July 24, 2015 |
November 28, 2018 |
|
- James J. Peters VA Medical Center, Bronx, NY
Bronx, New York, United States
|
|
| 33 |
NCT03770442 |
Not yet recruiting |
Muscle Wasting in the Critically Ill |
|
- Device: Cycling with FES
- Other: Routine physiotherapy
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Ultrasound assessment of rectus femoris - Change in cross sectional area (cm2)
- Ultrasound assessment of rectus femoris - Change in muscle layer thickness (cm)
- Ultrasound assessment of anterior thigh musculature - Change in muscle layer thickness (cm)
- (and 31 more...)
|
36 |
All |
18 Years to 90 Years (Adult, Older Adult) |
NCT03770442 |
UoL001367 |
|
January 1, 2019 |
August 2019 |
January 2020 |
December 10, 2018 |
December 10, 2018 |
|
|
|
| 34 |
NCT01570816 |
Recruiting |
Improving Ambulatory Community Access After Paralysis |
- Stroke
- Partial Paralysis
- Spinal Cord Injury
- (and 2 more...)
|
- Device: IRS-8 (8 channel implanted receiver stimulator)
|
Interventional
|
Phase 1 |
- Louis Stokes VA Medical Center
|
U.S. Fed |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- The effect of functional electrical stimulation of the hip, knee and ankle muscles to improve walking in people with partial paralysis
- Feasibility of initiating a step with a trigger from an accelerometer incorporated in the external control unit to adjust to environmental circumstances and situations encountered in community ambulation
|
6 |
All |
18 Years to 75 Years (Adult, Older Adult) |
NCT01570816 |
12004-H02
1I01RX000528-01A2 |
|
April 2012 |
July 2021 |
July 2021 |
April 4, 2012 |
March 14, 2018 |
|
- Louis Stokes Cleveland Dept. of Veterans Affairs Medical Center
Cleveland, Ohio, United States
|
|
| 35 |
NCT03453944 |
Recruiting |
NMES to Prevent Respiratory Muscle Atrophy in Mechanically Ventilated Patients |
- Mechanical Ventilation Complication
- Neuromuscular Electrical Stimulation
- Muscle Weakness
|
- Device: VentFree prototype (VF03-K) active stimulation
- Device: VentFree prototype (VF03-K) sham stimulation
|
Interventional
|
Not Applicable |
- University Medical Center Nijmegen
- Liberate Medical
- VU University Medical Center
- Canisius-Wilhelmina Hospital
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Outcomes Assessor)
- Primary Purpose: Prevention
|
- Thickness of the abdominal wall muscles
- Thickness of the diaphragm
- Thickness of the rectus abdominis muscle
- (and 7 more...)
|
20 |
All |
18 Years to 99 Years (Adult, Older Adult) |
NCT03453944 |
LM-RB-01 |
|
March 9, 2017 |
July 1, 2018 |
December 31, 2018 |
March 5, 2018 |
March 5, 2018 |
|
- UMC Nijmegen
Nijmegen, Gelderland, Netherlands - Canisius Wilhelmina Hospital
Nijmegen, Gelderland, Netherlands - VU University Medical Center
Amsterdam, Noord-Holland, Netherlands
|
|
| 36 |
NCT03473106 |
Recruiting |
Effect of Tourniquet Use on Muscle Thigh Function. |
- Pneumatic Tourniquet
- Muscle Weakness
|
- Device: Pneumatic tourniquet use
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Diagnostic
|
- Postoperative muscle dysfunction
- Basal upper and lower extremity blood pressures
- Upper and lower extremity blood pressures after spinal anesthesia
- (and 8 more...)
|
30 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT03473106 |
OAIC 919/17 |
|
April 24, 2018 |
March 2019 |
March 2019 |
March 22, 2018 |
April 26, 2018 |
|
- Hospital Clínico Universidad de Chile
Santiago, Metropolitana, Chile
|
|
| 37 |
NCT03580200 |
Recruiting |
Effects of Deep Trigger Point Dry Needling on Strength Measurements of the Gluteus Medius Musculature |
- Trigger Point
- Muscle Weakness
|
- Other: Trigger Point Dry Needling
|
Interventional
|
Not Applicable |
- Emily Slaven, PT, PhD
- Mount St Joseph University
- University of Indianapolis
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- The Degree of Change in the Strength of the Gluteus Medius Musculature Measured by a Hand Held Dynamometer
- The Degree of Change in the Strength of the Gluteus Medius Musculature Measured by Surface Electromyography
|
40 |
All |
18 Years to 50 Years (Adult) |
NCT03580200 |
0897-MSJU |
|
November 2018 |
May 2019 |
May 2019 |
July 9, 2018 |
November 21, 2018 |
|
- Mount St Joseph Univeristy
Cincinnati, Ohio, United States
|
|
| 38 |
NCT02919085 |
Recruiting |
Effect of Critical Patients Mobilization on Respiratory and Peripheral Muscle Strength and Functional Capacity. |
- Intensive Care Unit Syndrome
- Muscle Weakness
|
- Procedure: Early ambulation
|
Interventional
|
Not Applicable |
- Universidade Federal de Pernambuco
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Respiratory muscle strength
- Peripheral muscle strength
- Functional capacity
|
40 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT02919085 |
01110031483 |
|
December 2016 |
October 2017 |
December 2017 |
September 29, 2016 |
June 6, 2017 |
|
- Real Hospital Português de Beneficência
Recife, Pernambuco, Brazil
|
|
| 39 |
NCT03670563 |
Recruiting |
Training Intrinsic Foot Muscles |
|
- Other: Short foot exercise protocol
- Other: Short foot exercise plus NMES
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Reaching Distance
- Center of pressure during walking gait
- Changes in foot posture over loading conditions
- (and 4 more...)
|
45 |
All |
18 Years to 30 Years (Adult) |
NCT03670563 |
IRB# 29267 |
|
October 10, 2018 |
March 2019 |
March 2019 |
September 13, 2018 |
November 19, 2018 |
|
- Saint Louis University
Saint Louis, Missouri, United States
|
|
| 40 |
NCT03200678 |
Recruiting |
WEakness and Atrophy: isoKinetic With Surface Electromyography Assessment in ACL Surgery |
- Anterior Cruciate Ligament Injury
- Muscle Weakness
|
- Other: isokinetic assessment
|
Interventional
|
Not Applicable |
- Direction Centrale du Service de Santé des Armées
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Factorial Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
|
80 |
All |
18 Years to 45 Years (Adult) |
NCT03200678 |
2017-A00301-52
2017RC01 |
WEAKNESS |
May 7, 2018 |
September 2020 |
September 2020 |
June 27, 2017 |
May 24, 2018 |
|
- Hôpital d'Instruction des Armées Clermont-Tonnerre
Brest, France
|
|
| 41 |
NCT03567122 |
Recruiting |
Attentional Focus Influence During Cranio-Cervical Flexion Test |
- Neck; Anomaly
- Muscle Weakness
- Muscle Weakness Condition
|
- Other: Internal Focus of Attention
- Other: External Focus of Attention
- Other: Control
|
Interventional
|
Not Applicable |
- Federal University of Health Science of Porto Alegre
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change from baseline in Electromyographic Activity of Sternocleidomastoid
- Cranio-cervical Range of Motion
- Cranio-Cervical Flexion Test Performance
|
90 |
All |
18 Years to 60 Years (Adult) |
NCT03567122 |
MSS_ME_01 |
|
August 1, 2018 |
August 1, 2018 |
June 2019 |
June 25, 2018 |
August 21, 2018 |
|
- Universidade Federal de Ciências da Saúde
Porto Alegre, RS, Brazil
|
|
| 42 |
NCT03628365 |
Recruiting |
Can Beta-Hydroxy-beta-Methylbutyrate Supplementation Counteract Muscle Catabolism in Critically Ill Patients? |
- Critical Illness
- Muscle Weakness
|
- Dietary Supplement: HMB (beta-hydroxy beta-methylbutyrate)
|
Interventional
|
Not Applicable |
- Mette M Berger
- Texas A&M University
- Centre Hospitalier Universitaire Vaudois
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- Muscle mass of the thigh
- Body composition
- Protein synthesis and breakdown
- (and 2 more...)
|
30 |
All |
18 Years and older (Adult, Older Adult) |
NCT03628365 |
CER-2018-00556 |
HMB-ICU-CH |
September 17, 2018 |
December 31, 2020 |
June 30, 2021 |
August 14, 2018 |
September 18, 2018 |
|
- University of Lausanne Hospitals
Lausanne, Switzerland
|
|
| 43 |
NCT02839018 |
Recruiting |
Nutrient Pattern Analysis in Critically Ill Patients (NAChO) |
- Intensive Care Unit (ICU) Acquired Weakness (ICU - AW)
- Muscle Weakness
|
|
Observational
|
|
- University Hospital Inselspital, Berne
- Nestec Ltd.
|
Other / Industry |
- Observational Model: Other
- Time Perspective: Prospective
|
- Differences in blood nutrient levels over time in patients with/without ICU-AW (i.e. "ICU-AW group" vs. "no-ICU-AW group". Primary comparison of interest is between day 14 vs. day 6.
- Differences in blood nutrient levels over time in patients in "sepsis group" vs. "CNS group". Primary comparison of interest is between day 14 vs. day 6.
- Differences in urine nutrient levels over time in patients with/ without ICU-AW (i.e. "ICU-AW group" vs. "no-ICU-AW group". Primary comparison of interest is between day 14 vs. day 6.
- (and 2 more...)
|
100 |
All |
18 Years and older (Adult, Older Adult) |
NCT02839018 |
NAChO |
NAChO |
January 2017 |
December 2018 |
February 2019 |
July 20, 2016 |
March 12, 2018 |
|
- Inselspital, Dept of Intensive Care Medicine
Bern, Switzerland
|
|
| 44 |
NCT03662555 |
Not yet recruiting |
Effect of Neuromuscular Electrical Stimulation Combined With Blood Flow Restriction on Muscular and Cardiovascular Function |
- Muscle Weakness
- Muscle Atrophy
|
- Device: Neuromuscular electrical stimulation
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Quadriceps volume and muscle architecture (3D Ultrasound)
- Knee extension isometric, eccentric, concentric and endurance strength (Cybex)
- Voluntary activation
- (and 2 more...)
|
50 |
All |
18 Years to 45 Years (Adult) |
NCT03662555 |
Stmarys |
|
September 26, 2018 |
July 31, 2019 |
September 30, 2019 |
September 7, 2018 |
September 12, 2018 |
|
|
|
| 45 |
NCT02530723 |
Recruiting |
Functional Changes and Power Training in Older Women. |
- Sarcopenia
- Muscle Weakness
|
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Change in Stair-climb power
- Change in 400-meter walk test
- Change in Short Physical Performance Battery
- Change in 30-second chair stand test
|
50 |
Female |
70 Years and older (Older Adult) |
NCT02530723 |
27773 |
F-POW |
August 2015 |
December 2017 |
December 2017 |
August 21, 2015 |
October 26, 2017 |
|
- Athletic Centre; 55 Harbord Street
Toronto, Ontario, Canada
|
|
| 46 |
NCT01536327 |
Recruiting |
Biomarker for Metachromatic Leukodystrophy Disease |
- Peripheral Neuropathy
- Muscle Weakness
|
|
Observational
|
|
|
Industry |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Development of a new MS-based biomarker for the early and sensitive diagnosis of metachromatic leukodystrophy disease from the blood
- Testing for clinical robustness, specificity and long-term stability of the biomarker
|
1000 |
All |
Child, Adult, Older Adult |
NCT01536327 |
BMLD 06-2018 |
BioMeta |
August 20, 2018 |
August 2021 |
August 2021 |
February 22, 2012 |
January 10, 2019 |
|
- Children Hospital, Faculty of Medicine, Cairo University
Cairo, Egypt - Centogene AG
Rostock, Germany - Amrita Institute of Medical Sciences & Research Centre
Cochin, Kerala, India - (and 2 more...)
|
|
| 47 |
NCT03788577 |
Recruiting
New |
Impact of Oligonol to Cardiometabolic Risk and Muscular Health |
- Muscle Loss
- Muscle Weakness
- Quality of Life
|
- Dietary Supplement: Oligonol intake
- Dietary Supplement: Placebo
|
Interventional
|
Not Applicable |
- National Yang Ming University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Changes from baseline muscle after 12 weeks
- Changes from baseline fat content of leg after 12 weeks
- Changes form baseline chair-stand after 12 weeks
- (and 22 more...)
|
120 |
All |
50 Years and older (Adult, Older Adult) |
NCT03788577 |
2018-05-004B |
|
December 4, 2018 |
July 31, 2019 |
July 31, 2019 |
December 27, 2018 |
December 27, 2018 |
|
- Taipei Veteran General Hospital
Taipei, Taiwan
|
|
| 48 |
NCT03784456 |
Not yet recruiting
New |
Impact of Increased Protein Density Diet to Muscle Mass and Strength Among Mid-aged and Older Adults |
- Muscle Loss
- Muscle Weakness
- Fragility
|
- Dietary Supplement: 25% protein
- Dietary Supplement: 15% protein
|
Interventional
|
Not Applicable |
- National Yang Ming University
- Laurel Corporation, Taiwan
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Prevention
|
- Changes from baseline muscle strength after 12 weeks
- Changes form baseline QUALITY OF LIFE after 12 weeks
- Change from baseline Nutrition intake after 12 weeks
- (and 22 more...)
|
80 |
All |
40 Years to 75 Years (Adult, Older Adult) |
NCT03784456 |
19-001-A-2 |
|
January 1, 2019 |
December 31, 2019 |
December 31, 2019 |
December 24, 2018 |
December 24, 2018 |
|
- National Yang Ming University
Taipei, Taiwan
|
|
| 49 |
NCT03506204 |
Recruiting |
The Pelvic Floor Muscle Function in Chinese Primipara, a One-year Cohort Study |
- Pelvic Floor Muscle Weakness
- Postpartum
- Primiparity
|
|
Observational
|
|
- Peking Union Medical College Hospital
- Liuzhou Maternity and Child Healthcare Hospital
- Maternity and Child Health Hospital of Dali
- (and 22 more...)
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Maximum vaginal contraction pressure
- Pelvic floor muscle strength
- Pelvic floor muscle strength（repetition）
- (and 5 more...)
|
3120 |
Female |
18 Years to 50 Years (Adult) |
NCT03506204 |
JS-1549 |
|
May 10, 2018 |
December 31, 2020 |
December 31, 2020 |
April 24, 2018 |
May 11, 2018 |
|
- Peking Union Medical College Hospital, Chinese Academy of Medicine Sciences
Beijing, Beiing, China
|
|
| 50 |
NCT02348762 |
Recruiting |
Energetics and Function in Older Humans |
- Aging
- Erythrocyte Glutathione Deficiency
- Muscle Weakness
|
- Dietary Supplement: Cysteine (as n-acetylcysteine) and Glycine
|
Interventional
|
Phase 1 |
- Baylor College of Medicine
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
- Red blood cell concentrations of Glutathione measured by HPLC
|
20 |
All |
21 Years to 80 Years (Adult, Older Adult) |
NCT02348762 |
H-34686 Glutathione and Aging |
|
November 2014 |
December 2018 |
December 2018 |
January 28, 2015 |
January 26, 2018 |
|
- Baylor Metabolic Research Unit (MRU)
Houston, Texas, United States
|
|
| 51 |
NCT03789175 |
Not yet recruiting
New |
Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome |
- Cancer
- Skin Fibroblasts
- Muscle Weakness
|
- Dietary Supplement: Niagen
|
Interventional
|
Phase 1
Phase 2 |
- National Heart, Lung, and Blood Institute (NHLBI)
- National Institutes of Health Clinical Center (CC)
|
NIH |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
- intra-subject comparison of baseline to 12 wk NR supplementation PCr recovery Tc measurements using the 31P-MRS skeletal muscle submaximal exercise.
- Examine whether NR supplementation affects the respiratory capacity of blood mononuclear cells, CPET, self-reported symptoms of fatigue.
|
1 |
All |
18 Years to 70 Years (Adult, Older Adult) |
NCT03789175 |
190034
19-H-0034 |
|
January 22, 2019 |
June 3, 2019 |
July 12, 2021 |
December 28, 2018 |
January 17, 2019 |
|
- National Institutes of Health Clinical Center
Bethesda, Maryland, United States
|
|
| 52 |
NCT03786835 |
Not yet recruiting
New |
Healthy Older People Everyday (HOPE) - Role of Healthy Diet on Muscle and Bone Health |
- Muscle Weakness
- Bone Health
- Cognitive Decline
|
- Other: Protein supplementation and regular physical activity
|
Interventional
|
Not Applicable |
- National University Hospital, Singapore
- Health Promotion Board (HPB)
- Saw Swee Hock Shool of Public Health, National University of Singapore
|
Other |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Single (Investigator)
- Primary Purpose: Prevention
|
- Changes in frailty status
- Changes in lower extremity physical performance
- Changes in upper extremity muscle strength
- (and 17 more...)
|
1000 |
All |
65 Years and older (Older Adult) |
NCT03786835 |
2018/01183 |
HOPE-DIET |
January 2019 |
December 2020 |
December 2020 |
December 25, 2018 |
December 25, 2018 |
|
|
|
| 53 |
NCT03252132 |
Recruiting |
Resistance Training in Patients With Diabetic Neuropathy |
- Diabetes Mellitus, Type 2
- Polyneuropathy Diabetes
- Diabetes Complications
- (and 3 more...)
|
- Other: 12-week resistance training
|
Interventional
|
Not Applicable |
- Danish Pain Research Center
- Odense University Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Other
|
- Intraepidermal nerve fiber density (IENFD)
- Muscle strength (isokinetic strength)
|
180 |
All |
30 Years to 75 Years (Adult, Older Adult) |
NCT03252132 |
IDNC-DD2-MUSCLE |
|
August 10, 2017 |
December 31, 2018 |
June 1, 2019 |
August 17, 2017 |
July 13, 2018 |
|
- Danish Pain Research Center, Aarhus University Hospital
Aarhus, Denmark
|
|
| 54 |
NCT02778945 |
Recruiting |
Neuromuscular Blockade for Optimising Surgical Conditions During Spinal Surgery |
- Neuromuscular Block
- Orthopedic Disorder of Spine
- Muscle Weakness
|
- Drug: Rocuronium 0.9 mg/kg
- Drug: Rocuronium 0.6 mg/kg
|
Interventional
|
Not Applicable |
- The Catholic University of Korea
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Diagnostic
|
- the operation time
- back muscle stiffness ( 1. Shear Wave Ultrasound Elastography(SWE) )
- back muscle stiffness (2.Mechanical Tension Weighing Scale (MTWS) of mechanical dynamometer)
|
66 |
All |
19 Years and older (Adult, Older Adult) |
NCT02778945 |
ANESTHA-NMB1 |
|
September 2016 |
September 2018 |
December 2018 |
May 20, 2016 |
March 6, 2018 |
|
- Yeouido St. Mary's Hospital
Seoul, Korea, Republic of
|
|
| 55 |
NCT03743740 |
Not yet recruiting |
The Effect of Spinal Stabilization Exercises in Patients With Myasthenia Gravis |
|
- Other: Spinal stabilization exercise
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- muscle strength of extremity muscle in patient with Myasthenia Gravis
- fatigue perception
- fatigue
- (and 3 more...)
|
10 |
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT03743740 |
KA-17132 |
|
December 3, 2018 |
March 22, 2019 |
April 8, 2019 |
November 16, 2018 |
November 20, 2018 |
|
|
|
| 56 |
NCT03049956 |
Recruiting |
OVEMP in Myasthenia |
- Myasthenia Gravis, Ocular
|
- Diagnostic Test: Ocular vestibular evoced myogenic potentials
|
Interventional
|
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Primary Purpose: Diagnostic
|
- Decrement (as quantified in %) of repetitive 20 Hz ocular vestibular-evoked myogenic potentials (oVEMP)
|
200 |
All |
18 Years and older (Adult, Older Adult) |
NCT03049956 |
2016-01109 |
|
November 1, 2016 |
December 31, 2019 |
December 31, 2019 |
February 10, 2017 |
October 11, 2018 |
|
- University Hospital Zurich, Ophthalmology/Neurology Department
Zurich, Switzerland
|
|
| 57 |
NCT03597373 |
Recruiting |
Variables Predicting Reintubation After Thymectomy in Patients With Myasthenia Gravis |
|
|
Observational
|
|
- First Affiliated Hospital, Sun Yat-Sen University
|
Other |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- Risk Factors for Reintubation
|
99 |
All |
18 Years to 75 Years (Adult, Older Adult) |
NCT03597373 |
Reintubation |
|
January 1, 2017 |
January 1, 2019 |
January 1, 2019 |
July 24, 2018 |
July 24, 2018 |
|
- Genglong Liu
Guangzhou, Guangdong, China
|
|
| 58 |
NCT03196960 |
Recruiting |
Effects of Mobility Dose in Surgical Intensive Care Unit Patients |
- Sarcopenia
- Muscle Weakness
- Critical Illness
|
|
Observational
|
|
- Massachusetts General Hospital
- Technische Universität München
- Università degli Studi di Brescia
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Adverse Hospital Discharge Disposition
- Rectus Femoris Muscle Cross Sectional Area
- Mobility Dose as measured by the Mobilization Quantification Score (MQS)
- (and 13 more...)
|
150 |
All |
18 Years and older (Adult, Older Adult) |
NCT03196960 |
2016P002045 |
MQS |
May 22, 2017 |
December 2018 |
December 2018 |
June 23, 2017 |
September 6, 2018 |
|
- Massachusetts General Hospital
Boston, Massachusetts, United States - Klinikum Rechts der Isar
Munich, Bavaria, Germany - Università degli Studi di Brescia
Brescia, Lombardy, Italy
|
|
| 59 |
NCT00390104 |
Recruiting |
Molecular Analysis of Patients With Neuromuscular Disease |
- Limb-girdle Muscular Dystrophy
- Duchenne Muscular Dystrophy
- Becker Muscular Dystrophy
- Neuromuscular; Disorder, Hereditary
|
|
Observational
|
|
- Boston Children’s Hospital
- National Institute of Neurological Disorders and Stroke (NINDS)
|
Other / NIH |
- Observational Model: Family-Based
- Time Perspective: Prospective
|
|
1000 |
All |
up to 100 Years (Child, Adult, Older Adult) |
NCT00390104 |
03-12-205
5R01NS080929 |
|
January 2002 |
December 31, 2020 |
December 31, 2021 |
October 19, 2006 |
October 9, 2018 |
|
- Boston Children's Hospital
Boston, Massachusetts, United States
|
|
| 60 |
NCT03102294 |
Not yet recruiting |
Inspiratory Muscle Training in Chronic Thromboembolic Pulmonary Hypertension |
- Chronic Thromboembolic Pulmonary Hypertension
- Inspiratory Muscle Training
- Inspiratory Muscle Weakness
|
- Other: inspiratory muscle training
- Other: Placebo "training"
|
Interventional
|
Not Applicable |
- Federal University of São Paulo
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Outcomes Assessor)
- Primary Purpose: Treatment
|
- exercise capacity¨- cardiopulmonary exercise testing
- exercise capacity - 6-min walk test
- ventilatory responses
- peripheral oxygenation
|
32 |
All |
18 Years to 70 Years (Adult, Older Adult) |
NCT03102294 |
FUSaoPaulo2017 |
|
September 1, 2017 |
November 30, 2018 |
April 30, 2019 |
April 5, 2017 |
August 7, 2017 |
|
- SEFICE - Setor de Função Pulmonar e Fisiologia Clínica do Exercício
Sao Paulo, São Paul, Brazil
|
|
| 61 |
NCT03675490 |
Not yet recruiting |
ABLE (Arts-Based Exercise Enhancing LongEvity) |
- Aging
- Fall
- Muscle Weakness
- Mobility Limitation
|
- Behavioral: ABLE - exercise with interactive technology
|
Interventional
|
Not Applicable |
- McMaster University
- McMaster Institute for Research on Aging
- Physiotherapy Foundation of Canada
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Recruitment
- Retention
- Adherence
- (and 5 more...)
|
25 |
All |
65 Years and older (Older Adult) |
NCT03675490 |
ABLEPILOT |
|
October 2018 |
November 2019 |
January 2020 |
September 18, 2018 |
September 18, 2018 |
|
|
|
| 62 |
NCT03797976 |
Recruiting
New |
The Effects Of DBS Of Subthalamıc Nucleus On Functionality In Patıents With Parkinson's Disease: Short-Term Results |
- Parkinson Disease
- Surgery
- Respiration; Decreased
- Muscle Weakness
|
|
Interventional
|
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Functional exercise capacity
- Pulmonary functions
- Inspiratory and expiratory muscle strength (MIP, MEP)
- (and 2 more...)
|
10 |
All |
40 Years to 70 Years (Adult, Older Adult) |
NCT03797976 |
Hatay Mustafa Kemal U 1 |
|
January 1, 2018 |
January 30, 2019 |
March 30, 2019 |
January 9, 2019 |
January 9, 2019 |
|
- Hatay Mustafa Kemal University
Antakya, Hatay, Turkey
|
|
| 63 |
NCT02880735 |
Recruiting |
Ventilatory Response After Non Invasive Ventilation in Type 1 Myotonic Dystrophy |
- Myotonic Dystrophy 1
- Steinert Disease
|
- Device: Non Invasive Ventilation.
|
Interventional
|
Not Applicable |
- National Institute of Respiratory Diseases, Mexico
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Ventilatory Response to Chemical Stimuli
- Health Related Quality of Life Measured by Short Form 36 (SF-36)
- Dyspnoea evaluated by the modified scale of the Medical Research Council (mMRC)
- Sleep Quality assessed by The Pittsburgh Sleep Quality Index (PSQI)
|
27 |
All |
18 Years and older (Adult, Older Adult) |
NCT02880735 |
C46-15 |
|
September 2016 |
December 2018 |
April 2019 |
August 26, 2016 |
July 11, 2018 |
|
- National Institute Of Respiratory Diseases
Mexico, Mexico
|
|
| 64 |
NCT03055182 |
Recruiting |
Oxygenation of Paravertebral Muscles During Exercise in Chronic Low Back Pain Patients |
- Low Back Pain
- Rehabilitation Program
- Muscular Weakness
|
- Other: Physical rehabilitation program
|
Interventional
|
Not Applicable |
- University Hospital, Lille
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Factorial Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
- Deoxyhemoglobin
- Oxygen consumption
- Work rate
- (and 4 more...)
|
36 |
All |
20 Years to 60 Years (Adult) |
NCT03055182 |
2015_58
2016-A01151-50 |
OXYLOM |
January 2017 |
December 2019 |
December 2019 |
February 16, 2017 |
April 24, 2018 |
|
- Hôpital Swyngedhauw, CHRU
Lille, France
|
|
| 65 |
NCT03693521 |
Not yet recruiting |
Effects of Measurement of Handgrip Strength on Physical Activity Level for Patients With Diabetes Type 2 |
- Diabetes Mellitus, Type 2
- Physical Activity
- Muscular Weakness
|
- Device: Handgrip strength measurement
- Other: Standard care
|
Interventional
|
Not Applicable |
- Göteborg University
- Vastra Gotaland Region
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Supportive Care
|
- Change in physical activity level
- Change in handgrip strength
- Change in HbA1c
- (and 2 more...)
|
800 |
All |
Child, Adult, Older Adult |
NCT03693521 |
VGFOUREG-751161 |
|
February 1, 2019 |
October 1, 2020 |
October 1, 2020 |
October 3, 2018 |
November 2, 2018 |
|
|
|
| 66 |
NCT02012933 |
Available |
3,4-Diaminopyridine for Lambert-Eaton Myasthenic Syndrome (LEMS) and Congenital Myasthenia (CM) |
- Lambert-Eaton Myasthenic Syndrome (LEMS)
- Congenital Myasthenia (CM)
|
- Drug: 3,4-diaminopyridine
|
Expanded Access
|
|
- Tessa L Marburger
- Jacobus Pharmaceutical
- Oregon Health and Science University
|
Other / Industry |
|
|
|
All |
2 Years and older (Child, Adult, Older Adult) |
NCT02012933 |
Jacobus compassionate program |
|
|
|
|
December 17, 2013 |
April 21, 2015 |
|
- Oregon Health & Science University
Portland, Oregon, United States
|
|
| 67 |
NCT03615521 |
Recruiting |
Different Proprioceptive Neuromuscular Facilitation (PNF) Technique in Patients With Knee Osteoarthritis |
- Muscle Weakness
- Balance Disorders
- Knee Pain
- Knee Osteoarthritis
|
- Other: Hotpack
- Other: Ultrasound
- Other: Combine Exercise
- (and 2 more...)
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Quadriceps Femoris Muscle Strength
- Knee Proprioception (30-45 and 60 degree)
- KOOS score
- (and 6 more...)
|
35 |
All |
45 Years to 65 Years (Adult, Older Adult) |
NCT03615521 |
2017/09-36 (KA-17112) |
|
January 20, 2018 |
October 20, 2018 |
October 10, 2019 |
August 6, 2018 |
October 9, 2018 |
|
|
|
| 68 |
NCT02739464 |
Recruiting |
Effect of In-Patient Exercise Training on Length of Hospitalization in Burned Patients |
- Muscle Weakness
- Late Effect of Burn
- Muscle; Fatigue, Heart
- Burn Rehabilitation
|
- Other: Exercise + SOC PT/OT
- Other: SOC PT/OT
|
Interventional
|
Not Applicable |
- The University of Texas Medical Branch, Galveston
- United States Army Institute of Surgical Research
- University of Texas Southwestern Medical Center
- California State University, Sacramento
|
Other / U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Other
|
- change in lean muscle mass
- change in VO2 max
- change in distance walked over 6 minutes
|
96 |
All |
7 Years to 60 Years (Child, Adult) |
NCT02739464 |
SHC; IRB #14-0432 |
MP-10 |
July 2015 |
December 2019 |
December 2019 |
April 15, 2016 |
January 16, 2019 |
|
- University of California-Davis/Shriners Hospitals for Children-Sacramento
Davis, California, United States - University of Texas Southwestern Medical Center
Dallas, Texas, United States - University of Texas Medical Branch/Shriners Hospitals for Children-Galveston (lead site)
Galveston, Texas, United States - United States Army Institute of Surgical Research
San Antonio, Texas, United States
|
|
| 69 |
NCT03452254 |
Recruiting |
NIBS With mCIMT for Motor and Functional Upper Limb Recovery in Stroke Patients. |
- Stroke
- Upper Extremity Paresis
- Electric Stimulation
- Occupational Therapy
|
- Device: Active Bihemispheric Transcranial direct current Stimulation
- Device: Sham Bihemispheric Transcranial direct current Stimulation
- Other: Modified Constraint Induced Movement Therapy
|
Interventional
|
Not Applicable |
- University of Chile
- Comisión Nacional de Investigación Científica y Tecnológica
- Hospital Clínico Universidad de Chile
- (and 3 more...)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Upper Limb Motor Recovery.
- Upper Limb Functional Recovery.
- Independence in basic activities of daily living.
- Brain activation patterns.
|
70 |
All |
18 Years and older (Adult, Older Adult) |
NCT03452254 |
849/16 |
|
June 4, 2018 |
March 30, 2020 |
June 30, 2020 |
March 2, 2018 |
June 27, 2018 |
|
- Hospital San José
Santiago, Metropolitana, Chile - Hospital Clinico Universidad de Chile
Santiago, Metropolitana, Chile
|
|
| 70 |
NCT01734369 |
Recruiting |
Environmental Risk Factors for Myositis in Military Personnel |
- Dermatomyositis
- Adult Polymyositis
- Inclusion Body Myositis
- Myositis
|
|
Observational
|
|
- National Institute of Environmental Health Sciences (NIEHS)
- National Institutes of Health Clinical Center (CC)
|
NIH |
- Observational Model: Case-Control
- Time Perspective: Other
|
- Military Myositis Questionnaire
|
300 |
All |
18 Years to 90 Years (Adult, Older Adult) |
NCT01734369 |
130015
13-E-0015 |
|
November 22, 2012 |
September 30, 2019 |
September 30, 2019 |
November 27, 2012 |
January 18, 2019 |
|
- National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States
|
|
| 71 |
NCT03527797 |
Recruiting |
Diaphragm Protective Ventilation in the Intensive Care Unit |
- Critical Illness
- Muscle Weakness
- Muscle Damage
- (and 2 more...)
|
- Other: Titration of support level
|
Interventional
|
Not Applicable |
- VU University Medical Center
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Adequate diaphragm loading
- Pressure-time product of diaphragm activity
- Work of breathing
- (and 2 more...)
|
40 |
All |
18 Years and older (Adult, Older Adult) |
NCT03527797 |
NL62486.029.17 |
DiaPro |
May 16, 2018 |
May 30, 2019 |
May 30, 2019 |
May 17, 2018 |
May 17, 2018 |
|
- VU University medical center
Amsterdam, Noord-Holland, Netherlands
|
|
| 72 |
NCT02706314 |
Recruiting |
Impact of Human Blood Serum From Critically Ill Patients on Human Colon Neuronal Networks. |
- Critical Illness
- Multiple Organ Failure
- Polyneuropathy
- Myopathy
|
|
Observational
|
|
|
Other |
- Observational Model: Case-Control
- Time Perspective: Prospective
|
- Changes in the frequency and the amplitude of spontaneous contractions of colonic smooth muscle preparations induced by incubation with serum from critically ill patients with CIP, without CIP and healthy controls
- Changes in the amplitude, the integrated force and the time to first and last peak of contractions evoked by electric field stimulation in colonic smooth muscle preparations incubated with the above mentioned sera
- Incidence of CIP assessed by standardized nerve conduction study
- (and 6 more...)
|
60 |
All |
18 Years and older (Adult, Older Adult) |
NCT02706314 |
A 2016-0016 |
|
March 2016 |
December 2018 |
December 2018 |
March 11, 2016 |
October 16, 2018 |
|
- Intensive Care Unit PIT 1 and 2, University hospital Rostock
Rostock, Germany
|
|
| 73 |
NCT03473873 |
Recruiting |
Protective Role of Muscle Function for Early Features of Knee Osteoarthritis After Anterior Cruciate Ligament Injury |
- Knee Osteoarthritis
- Anterior Cruciate Ligament Injury
- Osteoarthritis, Knee
- Muscle Weakness
|
- Other: Measures of muscle function
|
Observational
|
|
- Lund University
- Oslo University Hospital
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Patient-reported pain
- Compositional MRI (T2 relaxation time and 3DPD)
|
100 |
All |
18 Years to 35 Years (Adult) |
NCT03473873 |
2016/319 |
SHIELD |
March 9, 2018 |
March 2022 |
March 2022 |
March 22, 2018 |
October 24, 2018 |
|
- May Arna Risberg
Oslo, Norway - Eva Ageberg
Lund, Sweden
|
|
| 74 |
NCT03293615 |
Not yet recruiting |
Exercise Capacity of Patients With Dermatomyosis |
|
|
Interventional
|
Not Applicable |
- University Hospital, Strasbourg, France
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Difference in the capacity of muscle fibers to consume oxygen in the muscle of patients i) with DM, ii) with other inflammatory myopathy, iii) without neuromuscular disease.
|
45 |
All |
18 Years and older (Adult, Older Adult) |
NCT03293615 |
6431 |
MIDE |
January 1, 2019 |
January 1, 2019 |
January 1, 2025 |
September 26, 2017 |
August 28, 2018 |
|
|
|
| 75 |
NCT03347656 |
Recruiting |
Effects of Mobility Dose on Discharge Disposition in Critically Ill Stroke Patients |
- Sarcopenia
- Stroke, Acute
- Muscle Weakness
- Critical Illness
|
|
Observational
|
|
- Beth Israel Deaconess Medical Center
- Massachusetts General Hospital
- Technische Universität München
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Adverse Hospital Discharge Disposition
- 90 day Barthel Index (hierarchical testing)
- Rectus Femoris Muscle Cross Sectional Area Rectus Femoris Muscle Cross Sectional Area
- (and 13 more...)
|
160 |
All |
18 Years and older (Adult, Older Adult) |
NCT03347656 |
2017P000528 |
|
October 12, 2017 |
October 2019 |
December 2019 |
November 20, 2017 |
December 3, 2018 |
|
- Massachusetts General Hospital
Boston, Massachusetts, United States - Beth Israel Deconess Medical Center
Boston, Massachusetts, United States - Klinikum rechts der Isar of Technische Universität München
Munich, Bavaria, Germany
|
|
| 76 |
NCT02918032 |
Recruiting |
International Registry Study of Neutral Lipid Storage Disease (NLSD) / Triglyceride Deposit Cardiomyovasculopathy (TGCV) and Related Diseases |
- Neutral Lipid Storage Disease
|
|
Observational
|
|
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
|
Other |
- Observational Model: Cohort
- Time Perspective: Other
|
- Period from the onset of symptoms of NLSD / TGCV to death from any cause
- Serum CK(Creatine Kinase) level
- Serum BNP(B-type Natriuretic Peptide) level
- (and 37 more...)
|
100 |
All |
Child, Adult, Older Adult |
NCT02918032 |
TRICVD1315 |
|
January 2014 |
December 2018 |
October 2020 |
September 28, 2016 |
December 19, 2017 |
|
- Stanford University
Stanford, California, United States - Columbia University
New York, New York, United States - University of Graz
Graz, Steiermark, Austria - (and 12 more...)
|
|
| 77 |
NCT03240601 |
Recruiting |
Spinal Cord Stimulation to Augment Activity Based Therapy |
- Spinal Cord Stimulation
- Walking
- Spasticity
- (and 2 more...)
|
- Device: Transcutaneous spinal cord stimulation
|
Interventional
|
Not Applicable |
- Shepherd Center, Atlanta GA
- Foundation Wings For Life
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change in Spasticity - Pendulum/Leg-drop Test
- Change in Walking Function - 10m Walk/Walking Speed
- Change in Spasticity - Ankle Clonus Test/Foot-drop test
- (and 8 more...)
|
28 |
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT03240601 |
696 |
|
July 1, 2017 |
July 2019 |
July 2019 |
August 7, 2017 |
September 10, 2018 |
|
- Shepherd Center, Inc.
Atlanta, Georgia, United States
|
|
| 78 |
NCT03151291 |
Recruiting |
Effects of WB-EMS and Specific Dietary Supplements on Cancer Patients |
- Cancer
- Cancer Cachexia
- Weight Loss
- (and 2 more...)
|
- Dietary Supplement: β-hydroxy-β-methylbutyrate (HMB)
- Dietary Supplement: L-carnitine (LC)
- Dietary Supplement: Eicosapentaenoic acid (EPA)
- Other: Whole-Body Electromyostimulation (WB-EMS)
|
Interventional
|
Not Applicable |
- University of Erlangen-Nürnberg Medical School
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Other
|
- Skeletal muscle mass
- Physical function - isometric muscle strength
- Physical function - Endurance
- (and 5 more...)
|
200 |
All |
18 Years and older (Adult, Older Adult) |
NCT03151291 |
EMS and DS Tumor 01 |
|
December 2016 |
March 31, 2019 |
April 2019 |
May 12, 2017 |
October 16, 2018 |
|
- Hector-Center for Nutrition, Exercise and Sports
Erlangen, Bavaria, Germany
|
|
| 79 |
NCT03714399 |
Not yet recruiting |
Muscle Recovery Following Aortic Surgery Induced ICUAW. |
- Aortic Diseases
- Intensive Care Unit Syndrome
- Intensive Care Neuropathy
- (and 3 more...)
|
|
Observational
|
|
- Barts & The London NHS Trust
- Queen Mary University of London
- Barts Charity
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- To observe the change in cross sectional area of the Rectus Femoris (RFcsa) during critical illness and recovery.
- To Observe a change in Hand Held Dynamometry strength (grip strength) and correlate this with RFcsa, function and HRQoL during critical illness and recovery.
- To observe a change in Knee straightening dynamometry, strength and joint moment (torque) and correlate this with RFcsa, function and HRQoL during critical illness and recovery.
- (and 11 more...)
|
100 |
All |
18 Years and older (Adult, Older Adult) |
NCT03714399 |
012396 (VARIANCE) |
VARIANCE |
February 8, 2019 |
August 1, 2020 |
August 1, 2020 |
October 22, 2018 |
January 16, 2019 |
|
- St Bartholomew's hospital (Barts NHS trust)
London, United Kingdom
|
|
| 80 |
NCT01425489 |
Recruiting |
Biomarker for Krabbe Disease: BioKrabbe |
- Irritability
- Seizures
- Feeding Difficulties
- (and 2 more...)
|
|
Observational
|
|
|
Industry |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Development of a new MS-based biomarker for the early and sensitive diagnosis of Krabbe disease from plasma
- Testing for clinical robustness, specificity and long-term stability of the biomarker
|
1000 |
All |
1 Year and older (Child, Adult, Older Adult) |
NCT01425489 |
BK 06-2018 |
BIOKRABBE |
August 20, 2018 |
August 2021 |
August 2021 |
August 30, 2011 |
January 10, 2019 |
|
- Children Hospital, Faculty of Medicine, Cairo University
Cairo, Egypt - Centogene AG
Rostock, Germany - Navi Mumbai Institute of Research In Mental And Neurological Handicap (NIRMAN)
Mumbai, India
|
|
| 81 |
NCT02490527 |
Recruiting |
Effects of Epicatechin on Statins for Mitochondrial Dysfunction and Impaired Exercise Capacity |
|
- Dietary Supplement: Pure epicatechin capsules (50mg)
- Drug: Simvastatin (40mg)
- Other: Placebo
|
Interventional
|
Not Applicable |
- University of California, San Diego
- American Heart Association
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Changes in Functional Capacity
|
50 |
All |
30 Years to 75 Years (Adult, Older Adult) |
NCT02490527 |
UCSD IRB |
|
June 2015 |
June 2019 |
June 2019 |
July 7, 2015 |
March 7, 2018 |
|
- University of California, San Diego
La Jolla, California, United States
|
|
| 82 |
NCT03206190 |
Recruiting |
The Pre-SPG4 Study |
- Hereditary Spastic Paraplegia
- Hereditary, Spastic Paraplegia, Autosomal Dominant
|
- Other: SPRS Score and clinical signs
- Behavioral: Cognition Testing using CANTAB
- Diagnostic Test: Lumbar Puncture and blood draw
- (and 4 more...)
|
Interventional
|
Not Applicable |
- University Hospital Tuebingen
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Diagnostic
|
- Identification of a change of recognizable signs or symptoms
- Subclinical progression (10m walking time)
- Subclinical progression (5-stair climbing test time)
- (and 13 more...)
|
200 |
All |
18 Years to 70 Years (Adult, Older Adult) |
NCT03206190 |
pre-SPG4 |
|
July 1, 2018 |
May 2027 |
May 2029 |
July 2, 2017 |
January 3, 2019 |
|
- University Hospital Tübingen, Center for Neurology
Tübingen, Germany
|
|
| 83 |
NCT03676478 |
Not yet recruiting |
Assessing Timing of Enteral Feeding Support in Esophageal Cancer Patients on Muscle functTion and Survival |
- Esophageal Cancer
- Nutrition Aspect of Cancer
- Postoperative Complications
- (and 3 more...)
|
- Other: delayed start enteral support @ POD5
|
Interventional
|
Not Applicable |
- University Hospital, Gasthuisberg
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Functional recovery
- 90-day mortality
- Complications following esophagectomy
- (and 13 more...)
|
300 |
All |
18 Years to 90 Years (Adult, Older Adult) |
NCT03676478 |
S61665
2018-002891-41
116000000382
T002018N |
EFECTS |
February 15, 2019 |
December 1, 2021 |
December 1, 2022 |
September 18, 2018 |
January 15, 2019 |
|
|
|
| 84 |
NCT03115840 |
Recruiting |
Measuring Outcomes of Activity in Intensive Care |
- Critical Illness
- Sepsis
- Mechanical Ventilation
- (and 4 more...)
|
|
Observational
|
|
- Vanderbilt University Medical Center
- National Institute on Aging (NIA)
|
Other / NIH |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Precipitating Events Project Disability Questionnaire
- Life Space Assessment Questionnaire
- Survival
- (and 8 more...)
|
312 |
All |
18 Years and older (Adult, Older Adult) |
NCT03115840 |
116157
1K76AG054864-01 |
MOSAIC |
March 27, 2017 |
July 1, 2020 |
July 1, 2021 |
April 14, 2017 |
February 13, 2018 |
|
- Vanderbilt University Medical Center
Nashville, Tennessee, United States
|
|
| 85 |
NCT02971072 |
Recruiting |
Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy |
- Acute Pain
- Atrophic
- Goals
- (and 9 more...)
|
- Procedure: Subacromial injection
- Other: Physical Therapy
|
Interventional
|
Not Applicable |
- University of Oregon
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
|
Other / NIH |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Rotator cuff activation after subacromial injection and exercise intervention, difference in rotator cuff voluntary activation between subjects and controls
- Rotator cuff activation after subacromial injection and exercise intervention, difference in specific rotator cuff muscle activation between subjects and controls
- Rotator cuff voluntary activation after subacromial injection
- (and 13 more...)
|
180 |
All |
21 Years to 45 Years (Adult) |
NCT02971072 |
05022014.005
1R01AR063713-01A1 |
|
July 2014 |
June 2020 |
June 2020 |
November 22, 2016 |
June 7, 2018 |
|
- University of Oregon
Eugene, Oregon, United States
|
|
| 86 |
NCT03510546 |
Recruiting |
Effect of Pyridostigmine (Mestinon) on Muscle Strength in Myasthenia Gravis |
|
- Drug: Pyridostigmine
- Drug: Placebo oral capsule
|
Interventional
|
Phase 4 |
- University of Aarhus
- Aarhus University Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change in QMG
- Change in muscle strength as assessed by dynamometry (Biodex System 3).
- Change in muscle fatigue as assessed by dynamometry (Biodex System 3).
- Change in MG Composite Score
|
44 |
All |
18 Years to 90 Years (Adult, Older Adult) |
NCT03510546 |
Mestinon2018 |
|
April 9, 2018 |
August 31, 2020 |
August 31, 2021 |
April 27, 2018 |
April 27, 2018 |
|
- Department of Neurology Aarhus University Hospital
Aarhus, Midtjylland, Denmark
|
|
| 87 |
NCT03579966 |
Recruiting |
Long Term Safety Study of Amifampridine Phosphate in MuSK-MG (Muscle Specific Tyrosine Kinase Myasthenia Gravis) |
|
- Drug: Amifampridine Phosphate
|
Interventional
|
Phase 3 |
- Catalyst Pharmaceuticals, Inc.
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Incidence of Treatment-Emergent Adverse Events (Safety and Tolerability)
|
70 |
All |
18 Years and older (Adult, Older Adult) |
NCT03579966 |
MSK-003 |
|
July 1, 2018 |
June 2020 |
September 2020 |
July 9, 2018 |
July 9, 2018 |
|
- UC Irvine
Irvine, California, United States - Rush University
Chicago, Illinois, United States - OSF Healthcare St. Francis Medical Center
Peoria, Illinois, United States - (and 12 more...)
|
|
| 88 |
NCT03059888 |
Recruiting |
Trial of Orencia in Patients With Myasthenia Gravis |
|
- Drug: Abatacept Injection
|
Interventional
|
Early Phase 1 |
- Johns Hopkins University
- Bristol-Myers Squibb
|
Other / Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Subjective Composite Score of Myasthenia Gravis (MG) Severity
- Objective Composite Score of Myasthenia Gravis (MG) Severity
- Muscle Strength (Dynamometry)
- (and 3 more...)
|
20 |
All |
16 Years to 85 Years (Child, Adult, Older Adult) |
NCT03059888 |
IRB00100059 |
|
April 12, 2017 |
January 2019 |
January 2019 |
February 23, 2017 |
September 28, 2018 |
|
- Johns Hopkins University
Baltimore, Maryland, United States
|
|
| 89 |
NCT03772587 |
Recruiting |
A Study to Evaluate the Safety, Tolerability, Efficacy, Pharmacokinetics and Pharmacodynamics of M281 Administered to Adults With Generalized Myasthenia Gravis |
- Generalized Myasthenia Gravis
|
|
Interventional
|
Phase 2 |
- Momenta Pharmaceuticals, Inc.
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Number of Participants With Adverse Events
- Change From Baseline in the Total Myasthenia Gravis - Activities of Daily Living (MG-ADL) Score at Day 57
- Change From Baseline in Total MG-ADL Score as a Function of Total Serum Immunoglobulin G (IgG) at Day 57
- (and 12 more...)
|
60 |
All |
18 Years and older (Adult, Older Adult) |
NCT03772587 |
MOM-M281-004
2018-002247-28 |
|
January 2019 |
January 2020 |
January 2020 |
December 11, 2018 |
January 9, 2019 |
|
- Momenta Investigational Site
Boca Raton, Florida, United States - Momenta Investigational Site
Saint Petersburg, Florida, United States - Momenta Investigational Site
Cordova, Tennessee, United States
|
|
| 90 |
NCT03759366 |
Not yet recruiting |
A Phase 3 Open-Label Study of Eculizumab in Pediatric Participants With Refractory Generalized Myasthenia Gravis (gMG) |
- Myasthenia Gravis
- Myasthenia Gravis, Juvenile Form
- Myasthenia Gravis, Generalized
|
|
Interventional
|
Phase 3 |
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change From Baseline In The QMG Total Score Over Time Regardless Of Rescue Treatment
- Change From Baseline In The Myasthenia Gravis-Activities Of Daily Living (MG-ADL) Score Over Time Regardless Of Rescue Treatment
- Change From Baseline In The MG Composite (MGC) Score Over Time Regardless Of Rescue Treatment
- (and 7 more...)
|
12 |
All |
6 Years to 17 Years (Child) |
NCT03759366 |
ECU-MG-303 |
|
December 2018 |
June 2021 |
July 2025 |
November 30, 2018 |
November 30, 2018 |
|
|
|
| 91 |
NCT02950155 |
Recruiting |
A Study Evaluating the Safety and Efficacy of Rituximab in Patients With Myasthenia Gravis |
- Generalized Myasthenia Gravis
|
- Drug: Rituximab
- Drug: Sodium Chloride solution
|
Interventional
|
Phase 3 |
- Fredrik Piehl
- Karolinska Institutet
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Percentage of patients with quantitative MG ascore (QMG) score ≤ 4 and a daily Prednisolon dose of ≤ 10mg at 16 weeks after administration of study drug/placebo.
- QMG score at 24 weeks after administration of study drug/placebo.
- MG-activities of daily living (ADL) score at 16 weeks after administration of study drug/placebo
- MG-quality of life (QoL) score at 16 weeks after administration of study drug/placebo
|
60 |
All |
18 Years and older (Adult, Older Adult) |
NCT02950155 |
EudraCT 2015-005749-30 |
Rinomax |
October 16, 2016 |
September 30, 2019 |
June 30, 2020 |
October 31, 2016 |
April 4, 2018 |
|
- Karolinska University Hospital
Stockholm, Solna, Sweden
|
|
| 92 |
NCT01047761 |
Recruiting |
Exercise for Stable Myasthenia Gravis |
|
|
Interventional
|
Phase 1 |
- Baltimore VA Medical Center
- University of Maryland
|
U.S. Fed / Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Cardiovascular Fitness, Economy of Gait, Physiologic Reserve
- Ambulatory function (6 minute walk, 5 day step activity and accelerometer data)
- Muscle strength by dynamometer
- (and 5 more...)
|
30 |
All |
18 Years to 70 Years (Adult, Older Adult) |
NCT01047761 |
Myasthenia and Exercise |
|
January 2010 |
December 2020 |
December 2020 |
January 13, 2010 |
November 1, 2016 |
|
- University of Maryland and Baltimore VA Medical Center
Baltimore, Maryland, United States
|
|
| 93 |
NCT02196467 |
Recruiting |
Transplantation of Myoblasts to Duchenne Muscular Dystrophy (DMD) Patients |
- Duchenne Muscular Dystrophy
|
- Biological: Myoblast transplantation
- Procedure: Saline injection
|
Interventional
|
Phase 1
Phase 2 |
- CHU de Quebec-Universite Laval
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Number of Participants with Serious and Non-Serious Adverse Events as a measure of safety.
- Percentage of dystrophin-positive fibers in a muscle biopsy 3 or 6 months after myoblast transplantation.
- Strength of the Extensor carpi radialis muscles.
- Presence of a cellular and humoral reaction against the donor antigens
|
10 |
Male |
16 Years and older (Child, Adult, Older Adult) |
NCT02196467 |
SIRUL 104501
299825 |
|
May 2014 |
January 2019 |
February 2019 |
July 22, 2014 |
July 25, 2018 |
|
- Children's Hospital London Health Sciences Centre
London, Ontario, Canada - Centre de recherche du CHU de Quebec - CHUL
Quebec, Canada
|
|
| 94 |
NCT01793168 |
Recruiting |
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford |
- Rare Disorders
- Undiagnosed Disorders
- Disorders of Unknown Prevalence
- (and 264 more...)
|
|
Observational
|
|
- Sanford Health
- National Ataxia Foundation
- International WAGR Syndrome Association
- (and 23 more...)
|
Other |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- To accelerate research into rare disorders by connecting individuals who are interested in research and who have been diagnosed with a rare disorder (or a disorder of unknown prevalence, or who are undiagnosed) with researchers who study rare diseases.
|
20000 |
All |
Child, Adult, Older Adult |
NCT01793168 |
03-10-014
Hypersomnia Foundation
National Ataxia Foundation
4p- Support Group
CdLS Foundation
Hyperacusis Research Limited
Kabuki Syndrome Network
Kawasaki Disease Foundation
Klippel-Feil Syndrome Freedom
Leiomyosarcoma Direct Research
MSS Support Group
ML4 Foundation
Stickler Involved People
IWSA
Soft Bones
PWN4PWN
aHUS
Klippel-Feil Syndrome Alliance
American MEN Support
Kleine-Levin Syndrome
All Things Kabuki
WSS Foundation
BIVA
ABDA
PROS Foundation (HLH)
Alagille Syndrome Association
Cure VCP Disease, Inc.
Lowe Syndrome Association
Pitt Hopkins
Cure Batten Disease
Hypnic Jerk/Sleep Myoclonus |
CoRDS |
July 2010 |
December 2100 |
December 2100 |
February 15, 2013 |
September 25, 2018 |
|
- Sanford Health
Sioux Falls, South Dakota, United States - Online Patient Enrollment System
Sydney, Australia
|
|
| 95 |
NCT03619772 |
Recruiting |
EMG Training for Altering Activation Patterns After Stroke |
- Stroke
- Weakness, Muscle
- Coordination Lack
|
- Other: Bilateral
- Other: Unilateral
|
Interventional
|
Not Applicable |
- Shirley Ryan AbilityLab
- North Carolina State University
- Marquette University
- Medical University of South Carolina
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change in mean completion time for timed test
|
20 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT03619772 |
STU00206747 |
|
June 28, 2018 |
October 31, 2020 |
October 31, 2022 |
August 8, 2018 |
January 17, 2019 |
|
- Shirley Ryan AbilityLab
Chicago, Illinois, United States
|
|
| 96 |
NCT03059420 |
Recruiting |
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies |
- Congenital Fibrosis of Extraocular Muscles
- Duane Retraction Syndrome
- Duane Radial Ray Syndrome
- (and 23 more...)
|
|
Observational
|
|
- Boston Children’s Hospital
- Howard Hughes Medical Institute
- National Eye Institute (NEI)
|
Other / NIH |
- Observational Model: Cohort
- Time Perspective: Other
|
- Identifying and characterizing genes important in normal development and function of the ocular motility system, cranial nerves and brainstem and associated with congenital cranial dysinnervation disorders and related anomalies.
|
20000 |
All |
Child, Adult, Older Adult |
NCT03059420 |
05-03-036R
R01EY015298 |
|
February 1, 2004 |
January 2022 |
January 2022 |
February 23, 2017 |
March 23, 2018 |
|
- Boston Children's Hospital
Boston, Massachusetts, United States
|
|
| 97 |
NCT01457443 |
Recruiting |
Biomarker for Pompe Disease: BioPompe |
- Cardiac Diseases
- Muscular Weakness
- Hepato-splenomegaly
- (and 4 more...)
|
|
Observational
|
|
|
Industry |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Development of a new MS-based biomarker for the early and sensitive diagnosis of Pompe disease from plasma
- Testing for clinical robustness, specificity and long-term stability of the biomarker
|
1000 |
All |
12 Months and older (Child, Adult, Older Adult) |
NCT01457443 |
BP 06-2018 |
BIOPOMPE |
August 20, 2018 |
August 2021 |
August 2021 |
October 24, 2011 |
January 10, 2019 |
|
- Children Hospital, Faculty of Medicine, Cairo University
Cairo, Egypt - Centogene AG
Rostock, Germany - Amrita Institute of Medical Sciences & Research Centre
Cochin, Kerala, India - (and 2 more...)
|
|
| 98 |
NCT03194997 |
Not yet recruiting |
Pilates and Dance to Breast Cancer Patients Undergoing Treatment |
- Breast Cancer
- Quality of Life
- Lymphedema
- (and 13 more...)
|
- Other: Dance
- Other: Pilates
|
Interventional
|
Not Applicable |
- Laboratório de Pesquisa em Lazer e Atividade Física
- Centro de Pesquisas Oncológicas
|
Other |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Quality of life
- Depressive Symptoms
- Body image
- (and 16 more...)
|
201 |
Female |
18 Years and older (Adult, Older Adult) |
NCT03194997 |
2.073.549 |
|
January 1, 2018 |
July 30, 2018 |
July 30, 2020 |
June 22, 2017 |
August 16, 2017 |
|
|
|
| 99 |
NCT03547687 |
Recruiting |
Neurosciences-Intensive Care Unit Electrical Stimulation |
- Intensive Care (ICU) Myopathy
|
- Device: Electrical Stimulation Treatment
|
Interventional
|
Phase 4 |
- Oregon Health and Science University
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Duration of intubation
- Length of NSICU stay
- Length of hospital stay
- (and 2 more...)
|
22 |
All |
18 Years and older (Adult, Older Adult) |
NCT03547687 |
STUDY00018079 |
|
August 10, 2018 |
March 2019 |
June 2019 |
June 6, 2018 |
August 21, 2018 |
|
- Oregon Health & Science University
Portland, Oregon, United States
|
|
| 100 |
NCT02944929 |
Recruiting |
The Effect of a Self-rehabilitation Program in Addition to Usual Treatment for Spasticity on Impairment and Activity Limitation in Patients With Spastic Hemiparesis Following Stroke |
|
- Other: Self-rehabilitation program
|
Interventional
|
Phase 4 |
- Assistance Publique - Hôpitaux de Paris
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Assessment of Goal Attainment Scaling (GAS).
- Assessment of the Functional Independence Measure (FIM)
- Assessment of Hemispatial neglect
- (and 2 more...)
|
220 |
All |
18 Years to 75 Years (Adult, Older Adult) |
NCT02944929 |
P150907 |
ADJU-TOX |
November 20, 2017 |
December 2020 |
March 2021 |
October 26, 2016 |
January 17, 2018 |
|
- Hôpital Raymond Poincaré
Garches, France
|
|
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