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31 studies found for:    merrimack pharmaceuticals
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Rank Status Study
1 Completed
Has Results
A Study of MM-121 Combination Therapy in Patients With Advanced Non-Small Cell Lung Cancer
Condition: Carcinoma, Non-Small-Cell Lung
Interventions: Drug: MM-121;   Drug: Erlotinib
2 Completed
Has Results
A Study of MM-121 With Paclitaxel in Platinum Resistant/ Refractory Advanced Ovarian Cancers
Conditions: Epithelial Ovarian Cancer;   Fallopian Tube Cancer;   Peritoneal Cancer
Interventions: Drug: MM-121;   Drug: Paclitaxel
3 Completed
Has Results
A Trial of Preoperative MM-121 With Paclitaxel in HER2-negative Breast Cancer
Conditions: ER Positive, Her2 Negative Breast Cancer Patients;   Triple Negative Breast Cancer Patients
Interventions: Drug: MM-121;   Drug: Paclitaxel
4 Completed A Study of MM-111 and Paclitaxel With Trastuzumab in Patients HER2 Positive Carcinomas of the Distal Esophagus, Gastroesophageal (GE) Junction and Stomach
Conditions: HER-2 Gene Amplification;   Esophagus Cancer;   Gastroesophageal Junction Cancer;   Stomach Cancer
Interventions: Drug: MM-111;   Drug: Paclitaxel;   Drug: Trastuzumab
5 Completed
Has Results
Study of MM-398 With or Without 5-FU/LV, Versus 5-FU/LV in Patients With Metastatic Pancreatic Cancer
Condition: Metastatic Pancreatic Cancer
Interventions: Drug: MM-398;   Drug: 5 Fluorouracil;   Drug: Leucovorin
6 Completed
Has Results
A Safety Study of MM-121 With Cetuximab and Irinotecan in Patients With Advanced Cancers
Conditions: Colorectal Cancer;   Squamous Cell Head and Neck Cancer;   Non-small Cell Lung Cancer;   Triple Negative Breast Cancer;   Other Tumors With EGFR Dependence
Interventions: Drug: MM-121;   Drug: Irinotecan;   Drug: Cetuximab
7 Recruiting A Study of MM-121 in Combination With Chemotherapy Versus Chemotherapy Alone in Heregulin Positive NSCLC
Conditions: Non-Small Cell Lung Cancer;   NSCLC;   Adenocarcinoma;   Squamous Cell Carcinoma;   Heregulin;   Large Cell Carcinoma
Interventions: Drug: MM-121;   Drug: Docetaxel;   Drug: Pemetrexed
8 Completed A Phase 1 Study of MM-141 in Patients With Advanced Solid Tumors
Condition: Hepatocellular Carcinoma
Intervention: Drug: MM-141
9 Recruiting A Phase 2 Study of MM-141 Plus Nab-paclitaxel and Gemcitabine in Front-line Metastatic Pancreatic Cancer
Condition: Pancreatic Cancer
Interventions: Drug: MM-141;   Drug: Placebo;   Drug: Gemcitabine;   Drug: Nab-Paclitaxel
10 Completed
Has Results
Safety Study of MM-121 in Combination With Multiple Anticancer Therapies in Patients With Advanced Solid Tumors
Condition: Solid Tumors
Interventions: Drug: MM-121;   Drug: Carboplatin;   Drug: Pemetrexed;   Drug: Cabazitaxel;   Drug: Gemcitabine
11 Completed A Phase 2 Study to Evaluate the Efficacy and Safety of 60mg of MM-093 in Patients With Active Rheumatoid Arthritis
Condition: Rheumatoid Arthritis
Intervention: Drug: MM-093
12 Completed Phase 2 Study of MM-093 to Treat Patients With Uveitis
Condition: Uveitis
Interventions: Drug: MM-093;   Other: Placebo
13 Completed
Has Results
A Study of MM-121 in Combination With Paclitaxel in Patients With Advanced Gynecologic and Breast Cancers
Conditions: Locally Advanced/Metastatic or Recurrent Ovarian Cancer, Fallopian Tube Cancer,;   Primary Peritoneal Cancer or Endometrial Cancer;   Locally Advanced/Metastatic Her2 Non Overexpressing Breast Cancer
Interventions: Drug: MM-121;   Drug: Paclitaxel
14 Completed
Has Results
Trial of Exemestane +/- MM-121 in Postmenopausal Women With Locally Advanced or Metastatic Estrogen Receptor Positive and/or Progesterone Receptor Positive Her2 Negative Breast Cancer
Condition: Her2 Negative Breast Cancer Patients
Interventions: Drug: MM-121;   Drug: Placebo;   Drug: Exemestane
15 Recruiting A Study Evaluating MM-310 in Patients With Solid Tumors
Conditions: Solid Tumors;   Urothelial Carcinoma;   Gastric Carcinoma;   Squamous Cell Carcinoma of the Head and Neck;   Ovarian Cancer;   Pancreatic Ductal Adenocarcinoma;   Prostate Adenocarcinoma;   Non-small Cell Lung Cancer;   Small Cell Lung Cancer;   Triple Negative Breast Cancer;   Endometrial Carcinoma;   Soft Tissue Sarcoma
Intervention: Drug: MM-310
16 Completed Safety and Efficacy Study of MM-093 in Patients With Chronic Plaque Psoriasis
Condition: Psoriasis
Intervention: Drug: MM-093
17 Completed Safety Study of the Drug MM-151 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment
Conditions: Advanced Solid Tumors;   Colorectal Cancer;   Squamous Cell Head and Neck Cancer;   Non Small Cell Lung Cancer;   Triple Negative Breast Cancer
Interventions: Drug: MM-151;   Drug: MM-151 + irinotecan
18 Completed
Has Results
Phase I Safety Study of the Drug MM-121 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment
Condition: Advanced Solid Tumors
Intervention: Drug: MM-121
19 Completed
Has Results
A Study of MM-111 in Patients With Advanced, Refractory Her2 Amplified, Heregulin Positive Cancers
Conditions: Her2 Amplified Solid Tumors;   Metastatic Breast Cancer
Intervention: Drug: MM-111
20 Completed Efficacy Study of MM-093 in Rheumatoid Arthritis Patients on Methotrexate (MTX)
Condition: Rheumatoid Arthritis
Intervention: Drug: MM-093

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Study has passed its completion date and status has not been verified in more than two years.