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5 studies found for:    medulloblastoma and methotrexate | Open Studies
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Rank Status Study
1 Recruiting Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors
Conditions: Recurrent Childhood Medulloblastoma;   Recurrent Childhood Ependymoma;   Childhood Atypical Teratoid/Rhabdoid Tumor;   Embryonal Tumor With Abundant Neuropil and True Rosettes;   Metastatic Malignant Neoplasm to the Leptomeninges
Interventions: Drug: Intra thecal methotrexate;   Drug: topotecan;   Drug: cyclophosphamide
2 Recruiting HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors
Conditions: Medulloblastoma;   Central Nervous System Embryonal Tumors
Interventions: Drug: Induction;   Drug: Single Cycle Intensive Chemotherapy;   Drug: Tandem 3 Cycle Intensive Chemotherapy
3 Recruiting Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain Tumors
Conditions: Brain Tumor,;   Malignant Neoplasm of Fourth Ventricle of Brain
Interventions: Procedure: Ommaya Reservoir;   Drug: Methotrexate
4 Recruiting Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children With Recurrent Posterior Fossa Brain Tumors
Condition: Brain Tumor Recurrent
Interventions: Drug: Methotrexate;   Drug: Etoposide;   Procedure: Ommaya Reservoir
5 Recruiting Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: Induction Chemotherapy;   Drug: Low-Risk Therapy;   Drug: High-Risk Therapy;   Drug: Intermediate-Risk Therapy

Study has passed its completion date and status has not been verified in more than two years.