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34 studies found for:    macitentan
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Rank Status Study
1 Recruiting Macitentan in Pulmonary Hypertension of Sickle Cell Disease
Conditions: Pulmonary Hypertension;   Sickle Cell Disease
Intervention: Drug: macitentan
2 Active, not recruiting Clinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT Instrument
Condition: Pulmonary Arterial Hypertension
Intervention: Drug: Macitentan
3 Completed Clinical Study on Macitentan, RT and TMZ Concurrent Therapy Followed by Maintenance Macitentan and TMZ in Newly Diagnosed Glioblastoma
Condition: Glioblastoma
Intervention: Drug: Macitentan in combination with RT and TMZ
4 Active, not recruiting Clinical Study to Assess the Long-term Safety, Tolerability, and Efficacy of Macitentan in Subjects With Eisenmenger Syndrome
Condition: Pulmonary Arterial Hypertension
Intervention: Drug: Macitentan 10 mg tablet, once daily.
5 Terminated Clinical Study of Macitentan in Patients With PAH to Psychometrically Validate PAH-SYMPACT Instrument
Condition: Pulmonary Arterial Hypertension
Intervention: Drug: Macitentan
6 Recruiting REPAIR: Right vEntricular Remodeling in Pulmonary ArterIal hypeRtension
Condition: Pulmonary Arterial Hypertension
Intervention: Drug: Macitentan
7 Active, not recruiting Clinical Study to Assess the Safety, Tolerability and Efficacy of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension
Condition: Chronic Thromboembolic Pulmonary Hypertension
Intervention: Drug: Macitentan
8 Terminated A Pulmonary Arterial Hypertension Study With Macitentan to Validate the PAH-SYMPACT™ in France, Italy and Spain
Condition: Pulmonary Arterial Hypertension
Intervention: Drug: Macitentan
9 Completed Clinical Study to Evaluate the Effects of Macitentan on Exercise Capacity in Subjects With Eisenmenger Syndrome
Condition: Pulmonary Arterial Hypertension
Interventions: Drug: Macitentan 10 mg;   Drug: Placebo
10 Completed Clinical Study to Assess the Efficacy, Safety and Tolerability of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension
Condition: Chronic Thromboembolic Pulmonary Hypertension
Interventions: Drug: Macitentan;   Drug: Placebo
11 Terminated
Has Results
Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients
Condition: Digital Ulcers
Interventions: Drug: Macitentan 3 mg;   Drug: Macitentan 10 mg;   Drug: Placebo
12 Completed
Has Results
Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients
Conditions: Systemic Sclerosis;   Ulcers
Interventions: Drug: macitentan 3mg;   Drug: macitentan 10mg;   Drug: placebo
13 Completed
Has Results
Macitentan Use in an Idiopathic Pulmonary Fibrosis Clinical Study
Condition: Idiopathic Pulmonary Fibrosis
Interventions: Drug: ACT-064992 (macitentan);   Drug: Placebo
14 Terminated Clinical Study on the Safety and Tolerability of Macitentan in Combination With Dose-dense Temozolomide in Patients With Recurrent Glioblastoma
Condition: Glioblastoma
Interventions: Drug: Phase 1 Dose Escalation;   Drug: Phase 1b;   Drug: Ancillary Study
15 Not yet recruiting Macitentan in the Treatment of Organ Rejection After Lung Transplantation
Condition: Lung Transplant Rejection
Interventions: Drug: macitentan;   Drug: placebo (for macitentan)
16 Withdrawn Safety and Tolerability Study of Macitentan in Patients With Idiopathic Pulmonary Fibrosis
Condition: Idiopathic Pulmonary Fibrosis
Intervention: Drug: Macitentan
17 Recruiting PORtopulmonary Hypertension Treatment wIth maCitentan ─ a randOmized Clinical Trial
Condition: Portopulmonary Hypertension
Interventions: Drug: Macitentan;   Other: Placebo
18 Recruiting OPsumit USers Registry
Condition: Pulmonary Arterial Hypertension
Intervention: Drug: Opsumit (macitentan)
19 Active, not recruiting Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension
Condition: Pulmonary Arterial Hypertension
Intervention: Drug: Macitentan
20 Active, not recruiting Extension of the Psychometric Validation Study ORCHESTRA in Patients With PAH
Condition: Pulmonary Arterial Hypertension
Intervention: Drug: Macitentan

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Study has passed its completion date and status has not been verified in more than two years.