1 |
NCT00061412 |
Completed |
Comprehensive Program to Improve Reading and Writing Skills in At-Risk and Dyslexic Children |
- Dyslexia
- Learning Disorders
|
- Behavioral: Comprehensive program to improve reading and writing skills
|
Interventional |
Not Applicable |
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
NIH |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Single
- Primary Purpose: Treatment
|
|
2500 |
All |
6 Years and older (Child, Adult, Senior) |
NCT00061412 |
2P50HD33812-6 |
|
December 1995 |
|
November 2005 |
May 28, 2003 |
September 28, 2006 |
|
- University of Washington
Seattle, Washington, United States
|
2 |
NCT02964884 |
Recruiting |
Interventions for Reading Disabilities in NF1 |
- Neurofibromatosis Type 1
- Learning Disability
- Reading Disability
- NF1
|
- Drug: Lovastatin
- Behavioral: reading tutoring intervention
- Drug: Placebo Oral Tablet
- Behavioral: Other Academic "sham" tutoring
|
Interventional |
Phase 2 |
- Vanderbilt University
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Treatment
|
- Woodcock Johnson Tests of Achievement IV
- Woodcock Reading Mastery Test-III
- Test of Word Reading Efficiency-2
- (and 7 more...)
|
120 |
All |
8 Years to 20 Years (Child, Adult) |
NCT02964884 |
161159 1R01HD089474-01 |
|
November 2016 |
November 2020 |
June 2022 |
November 16, 2016 |
February 6, 2018 |
|
- Vanderbilt University
Nashville, Tennessee, United States
|
3 |
NCT00809055 |
Completed Has Results |
MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine |
- Apnea of Prematurity
- Intraventricular Hemorrhage
- Brain Injury
|
|
Interventional |
Phase 4 |
- Washington University School of Medicine
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- White Matter Microstructural Maturation
- Mortality Rates
- Cerebellar Hemorrhage
- (and 7 more...)
|
74 |
All |
24 Weeks to 30 Weeks (Child) |
NCT00809055 |
08-0849 R01HD057098-01 HRPO 08-0849 |
|
November 2008 |
December 2010 |
December 2015 |
December 16, 2008 |
February 24, 2016 |
February 24, 2016 |
- St. Louis Children's Hospital
St. Louis, Missouri, United States
|
4 |
NCT03025763 |
Recruiting |
Network Of Clinical Research Studies On Craniosynostosis, Skull Malformations With Premature Fusion Of Skull Bones |
|
- Other: Craniosynostosis Network Environmental Survey
- Other: 2D/3D Photography
- Procedure: Buccal Swab Cell Sampling
- (and 4 more...)
|
Observational |
|
- Icahn School of Medicine at Mount Sinai
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Observational Model: Other
- Time Perspective: Other
|
- Phenotype-genotype gene expression correlations
- Incidence of gene mutations
|
4000 |
All |
up to 80 Years (Child, Adult, Senior) |
NCT03025763 |
GCO 13-0147 P01HD078233 |
|
November 2014 |
June 2019 |
June 2029 |
January 20, 2017 |
January 23, 2018 |
|
- The International Craniosynostosis Consortium at University of California at Davis
Davis, California, United States - Yale University
Hartford, Connecticut, United States - National Birth Defects Prevention Study at University of Iowa
Iowa City, Iowa, United States - (and 13 more...)
|
5 |
NCT00110292 |
Unknown † |
Preventing Learning Problems in Young Children: A Public Health and Physician-Based Outreach |
- Developmental Disabilities
- Language Development Disorders
|
- Behavioral: Age-specific parenting newsletters and developmental toys
- Behavioral: Parent-completed Ages & Stages Questionnaires
- Behavioral: Clinic-based distribution of children's books
|
Interventional |
Phase 1 |
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
NIH |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Single
- Primary Purpose: Prevention
|
|
600 |
All |
4 Months to 7 Months (Child) |
NCT00110292 |
R01HD040388 |
|
March 2002 |
|
February 2006 |
May 6, 2005 |
June 24, 2005 |
|
- Montefiore Comprehensive Health Care Center
Bronx, New York, United States - North Central Bronx Hospital Pediatric Clinic
Bronx, New York, United States
|
6 |
NCT00494260 |
Completed |
Managing Recurrent Abdominal Pain |
|
- Behavioral: Social Learning and Cognitive Behavioral Therapy (SLCBT)
- Behavioral: Education Support (ES)
|
Interventional |
Phase 2 |
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- symptoms of recurrent abdominal pain
- disability
- parent behaviors
- child coping behaviors
|
200 |
All |
7 Years to 17 Years (Child) |
NCT00494260 |
R01HD036069-07 |
|
November 2003 |
June 2010 |
June 2010 |
June 29, 2007 |
March 31, 2016 |
|
- Goryeb Children's Hospital/ Atlantic Health System
Morristown, New Jersey, United States - University of Washington/ Children's Hospital and Regional Medical Center
Seattle, Washington, United States
|
7 |
NCT03419611 |
Recruiting |
Word Learning in Children With Autism |
- Autistic Disorders Spectrum
|
- Behavioral: Multi-Modal
- Other: Treatment as Usual
|
Interventional |
Not Applicable |
- University of Kansas
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Sequential Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Word Acquisition
- Vineland Adaptive Behavior Scale 3
- Communication Complexity Scale
- (and 2 more...)
|
60 |
All |
5 Years to 10 Years (Child) |
NCT03419611 |
STUDY00140285 U54HD090216 |
|
November 1, 2016 |
May 31, 2021 |
May 31, 2021 |
February 2, 2018 |
February 2, 2018 |
|
- University of Kansas
Lawrence, Kansas, United States
|
8 |
NCT03485820 |
Recruiting New |
A Novel Transition Program to Reduce Disability After Stroke |
- Ischemic Stroke
- Hemorrhagic Stroke
|
- Behavioral: COMPASS
- Behavioral: Stroke education
|
Interventional |
Not Applicable |
- Washington University School of Medicine
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Reintegration to Normal Living Index (RNLI)
- Stroke Impact Scale (SIS)
- In-Home Occupational Performance Evaluation (I-HOPE)
|
156 |
All |
50 Years and older (Adult, Senior) |
NCT03485820 |
201705047 1R01HD092398-01 |
COMPASS |
January 18, 2018 |
June 2021 |
June 2021 |
April 2, 2018 |
April 25, 2018 |
|
- Washington University School of Medicine
Saint Louis, Missouri, United States
|
9 |
NCT00802724 |
Completed |
Classification-Directed Treatment of Low Back Pain |
|
- Behavioral: Classification-directed treatment
- Behavioral: Non-specific treatment
|
Interventional |
Phase 1 |
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- Washington University School of Medicine
|
NIH / Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Modified Oswestry Disability Index for Low Back Pain (0-100%)
- Kinematic measures of select movements and postures
- Numeric pain rating scale (0-10 points)
- (and 16 more...)
|
101 |
All |
18 Years to 60 Years (Adult) |
NCT00802724 |
HD047709-04 |
|
February 2007 |
August 2009 |
November 2010 |
December 5, 2008 |
October 22, 2012 |
|
- Washington University
Saint Louis, Missouri, United States
|
10 |
NCT00913211 |
Completed |
Repetitive Transcranial Magnetic Stimulation (rTMS) to Promote Hand Recovery in Stroke |
|
- Device: rTMS
- Procedure: Motor learning training
- Procedure: rTMS and Tracking
- Device: Sham rTMS
|
Interventional |
Phase 1 |
- University of Minnesota - Clinical and Translational Science Institute
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- box and block finger prehension test
- cortical excitability
- cognitive function
|
40 |
All |
21 Years to 90 Years (Adult, Senior) |
NCT00913211 |
0704M06701 1R01HD053153-01A2 |
rTMS |
September 2007 |
August 2011 |
August 2011 |
June 4, 2009 |
August 31, 2011 |
|
- University of Minnesota
Minneapolis, Minnesota, United States
|
11 |
NCT02855008 |
Recruiting |
Steps to Effective Problem Solving in Group Homes |
|
- Behavioral: STEPS
- Behavioral: Food for Life
|
Interventional |
Not Applicable |
- Rush University Medical Center
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- The Iowa Family Interactions Rating Scales (IFIRS) Individual-level Problem-solving scales
- Problem-solving Task (PST)
- The IFIRS Dyadic-interaction scales
- (and 5 more...)
|
288 |
All |
18 Years and older (Adult, Senior) |
NCT02855008 |
R01HD086211 1R01HD086211-01A1 |
STEPS |
April 5, 2016 |
January 2020 |
September 2020 |
August 4, 2016 |
April 12, 2017 |
|
- Rush University Medical Center
Chicago, Illinois, United States
|
12 |
NCT00679003 |
Completed |
Managing Inflammatory Bowel Disease |
- Inflammatory Bowel Disease
- Crohn's Disease
- Ulcerative Colitis
|
- Behavioral: SLCBT
- Behavioral: ES
|
Interventional |
Not Applicable |
- University of Washington
- National Institutes of Health (NIH)
- Seattle Children's Hospital
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Functional Disability Inventory
- School absences
- Health care utilization for IBD
- Pediatric Quality of Life
|
190 |
All |
8 Years to 17 Years (Child) |
NCT00679003 |
CHRMC12395 1R01HD050345-01A2 |
Managing IBD |
September 2007 |
March 2014 |
March 2014 |
May 16, 2008 |
April 15, 2015 |
|
|
13 |
NCT01934621 |
Recruiting |
Adapting Daily Activity Performance Through Strategy Training |
- Strategy Training
- Attention Control
|
- Behavioral: Strategy Training
- Behavioral: Attention Control
|
Interventional |
Not Applicable |
- University of Pittsburgh
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change in Independence with Daily Activities
- Change in Executive Functions
|
120 |
All |
18 Years and older (Adult, Senior) |
NCT01934621 |
PRO13070029 R01HD074693 |
ADAPTS |
November 2013 |
August 2018 |
December 2018 |
September 4, 2013 |
August 17, 2017 |
|
- University of Pittsburgh
Pittsburgh, Pennsylvania, United States
|
14 |
NCT02225041 |
Recruiting |
Sedation Strategy and Cognitive Outcome After Critical Illness in Early Childhood |
- Intellectual Disability
- Perceptual Disorders
- Memory Disorders
|
|
Observational |
|
- University of Pennsylvania
- National Institutes of Health (NIH)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Observational Model: Case-Control
- Time Perspective: Cross-Sectional
|
- Neurocognitive function at 2.5 years post-ICU discharge, as assessed using standardized tests of attention, processing speed, learning and memory, visual-spatial skills, motor skills, language, executive function, IQ, and behavior
|
810 |
All |
30 Months to 13 Years (Child) |
NCT02225041 |
1R01HD074757-01A1 |
RESTORE-cog |
August 2014 |
May 2018 |
May 2018 |
August 25, 2014 |
June 20, 2017 |
|
- Children's Hospital of Alabama
Birmingham, Alabama, United States - University Medical Center, The University of Arizona
Tucson, Arizona, United States - Children's Hospital and Research Center at Oakland
Oakland, California, United States - (and 28 more...)
|
15 |
NCT01800604 |
Active, not recruiting |
Power Over Pain (POP) Study |
- Multiple Sclerosis
- Spinal Cord Injury
- Chronic Pain
- (and 3 more...)
|
- Behavioral: Pain Self-Management Intervention #1
- Behavioral: Pain Self-Management Intervention #2
- Behavioral: Pain Self-Management Intervention #3
- Behavioral: Pain Self-Management Intervention #4
|
Interventional |
Not Applicable |
- University of Washington
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- National Institutes of Health (NIH)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change in average pain intensity pre-treatment to post-treatment
|
177 |
All |
18 Years and older (Adult, Senior) |
NCT01800604 |
43605 1R01HD070973 |
POP |
February 2013 |
February 2018 |
February 2018 |
February 27, 2013 |
October 2, 2017 |
|
- University of Washington, Ninth and Jefferson Building
Seattle, Washington, United States
|
16 |
NCT01085604 |
Completed |
Recurrent Low Back Pain:Linking Mechanisms to Outcomes |
|
- Other: Core Stabilization
|
Observational |
|
- Drexel University
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Trunk Neuromuscular Control
- Oswestry Disability Index
|
69 |
All |
18 Years to 65 Years (Adult) |
NCT01085604 |
K01HD053632T K01HD053632 |
|
August 2009 |
April 2015 |
June 2015 |
March 12, 2010 |
August 5, 2015 |
|
- Drexel University
Philadelphia, Pennsylvania, United States - Optimum Physical Therapy Associates
West Chester, Pennsylvania, United States
|
17 |
NCT00965068 |
Completed |
Cholesterol in ASD: Characterization and Treatment |
- Autism
- Asperger Disorder
- PDD-NOS
|
|
Interventional |
Phase 1 Phase 2 |
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- National Institutes of Health Clinical Center (CC)
|
NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Primary Purpose: Treatment
|
|
44 |
All |
4 Years to 12 Years (Child) |
NCT00965068 |
090203 09-CH-0203 |
|
July 28, 2009 |
|
November 14, 2013 |
August 25, 2009 |
October 6, 2017 |
|
- National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States
|
18 |
NCT01611792 |
Completed Has Results |
Effects and Mechanisms of Specific Trunk Exercises in Low Back Pain |
|
- Other: Stabilization exercise protocol
- Other: Strength and conditioning exercise protocol
|
Interventional |
Not Applicable |
- University of Vermont
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change From Baseline to 11 Weeks in Oswestry Disability Scale (0-100%)
- Change From Baseline to 6 Months in Oswestry Disability Scale (0-100%)
- Change From 11 Weeks to 6 Months in Oswestry Disability Scale (0-100%)
- (and 3 more...)
|
58 |
All |
21 Years to 55 Years (Adult) |
NCT01611792 |
NIH/NCMRR/R01-HD040909 |
|
March 2003 |
June 2008 |
June 2008 |
June 5, 2012 |
October 18, 2017 |
August 21, 2017 |
- Human Motion Analysis Laboratory
Burlington, Vermont, United States
|
19 |
NCT02913222 |
Recruiting |
Movement Pattern Training in People With Intra-articular, Prearthritic Hip Disorders |
- Chronic Hip Joint Pain
- Prearthritic Hip Disease
|
|
Interventional |
Not Applicable |
- Washington University School of Medicine
- University of Pittsburgh
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Percentage of participants who are adherent to treatment attendance
- Improvement in function using the Hip disability and Osteoarthritis Outcome Score (HOOS) Activities in Daily Living subscale
- Improvement in Hip disability and Osteoarthritis Outcome Score (HOOS) Symptoms subscale
|
46 |
All |
15 Years to 40 Years (Child, Adult) |
NCT02913222 |
R21HD086644-01A1 |
|
February 4, 2017 |
December 2018 |
December 2019 |
September 23, 2016 |
July 19, 2017 |
|
- Program in Physical Therapy, Washington University
Saint Louis, Missouri, United States - University of Pittsburgh
Pittsburgh, Pennsylvania, United States
|