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10 studies found for:    hydroxycamptothecin
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Rank Status Study
1 Completed A Phase I Study of AR-67 (7-t-butyldimethylsilyl-10-hydroxycamptothecin) Given on Days 1, 4 8, 12 & 15 of an Every 21-day Cycle in Adult Patients With Refractory or Metastatic Solid Malignancies
Condition: Solid Malignancies
Intervention: Drug: 7-t-butyldimethylsilyl-10-hydroxycamptothecin
2 Unknown  Study of AR-67 in Adult Patients With Recurrence of Glioblastoma Multiforme (GBM) or Gliosarcoma
Conditions: Glioblastoma Multiforme;   GBM;   Gliosarcoma
Intervention: Drug: AR-67 (7-t-butyldimethylsiltyl-10-hydroxy-camptothecin)
3 Unknown  Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS)
Condition: Myelodysplastic Syndrome
Intervention: Drug: AR-67 (20S)-7-t-Butyldimethylsilyl-10-hydroxycamptothecin)
4 Completed Study of AR-67 (Formerly DB-67) in Adult Patients With Refractory or Metastatic Solid Malignancies
Condition: Tumors
Intervention: Drug: AR-67 (formerly DB-67)
5 Recruiting Safety and Pharmacokinetic Study of IT-141 in Monotherapy in Patients With Advanced Cancer
Conditions: Cancer;   Neoplasms;   Tumors;   Refractory Solid Tumors;   Recurrent Solid Tumors
Intervention: Drug: IT-141
6 Recruiting Liver Resection Versus Transarterial Chemoembolization for the Treatment of Intermediate-stage Hepatocellular Carcinoma
Condition: Hepatocellular Carcinoma
Interventions: Procedure: liver resection;   Procedure: transarterial chemoembolization;   Drug: carboplatin;   Drug: lipiodol;   Drug: epirubicin , pirarubicin , hydroxycamptothecin and fluorouracil;   Other: absorbable gelatin sponge particles
7 Completed Chemotherapy in Treating Children With Relapsed Acute Leukemia, Acute Myeloid Leukemia, or Blastic Phase Chronic Myelogenous Leukemia
Condition: Leukemia
Intervention: Drug: topotecan hydrochloride
8 Completed Study of Glutamine as Prophylaxis for Irinotecan Induced Diarrhea
Condition: Metastatic Colorectal Cancer
Interventions: Drug: Glutamine;   Other: Placebo
9 Completed Phase I Study of Interperitoneal Chenotherapy in Patients With Gastric Adenocarainoma With Peritoneal Seeding
Condition: Stomach Neoplasms
Intervention: Drug: irinotecan
10 Completed
Has Results
Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma
Conditions: Anaplastic Astrocytomas;   Anaplastic Oligodendrogliomas;   Glioblastomas (GBM)
Intervention: Drug: Etirinotecan pegol

Study has passed its completion date and status has not been verified in more than two years.