46 studies found for:    human epidermal growth factor receptor type 2 (HER2)
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Rank Status Study
1 Active, not recruiting Evaluation of Trastuzumab Without Chemotherapy as a Postoperative Adjuvant Therapy in HER2 Positive Elderly Breast Cancer Patients
Condition: Breast Cancer
Interventions: Drug: trastuzumab;   Drug: chemotherapy
2 Recruiting A Study to Develop Predictive and Prognostic Tools for Optimizing Therapy With Bevacizumab Frontline Cancer Therapy in Patients With Metastatic Her 2- Negative and Aggressive Disease Criteria
Condition: Metastatic Breast Cancer
Interventions: Drug: Bevacizumab;   Drug: Paclitaxel
3 Completed
Has Results
A Phase Ib Expansion Study Investigating the Safety, Efficacy, and Pharmacokinetics of Intravenous CUDC-101 in Subjects With Advanced Head and Neck, Gastric, Breast, Liver and Non-small Cell Lung Cancer Tumors
Conditions: Head and Neck Cancer;   Liver Cancer;   Breast Cancer;   Gastric Cancer;   Non-Small Cell Lung Cancer
Intervention: Drug: CUDC-101
4 Completed A Phase I Study of the Safety, Pharmacokinetics, and Anti-Tumor Activity of CUDC-101 in Patients With Advanced Solid Tumors
Condition: Tumors
Intervention: Drug: CUDC-101
5 Completed Phase I Study of CUDC-101 With Cisplatin and Radiation in Subjects With Head & Neck Cancer
Condition: Head and Neck Cancer
Interventions: Drug: CUDC-101;   Drug: Cisplatin;   Radiation: Radiation Therapy
6 Completed The Treatment of Lapatinib in Combination With Sorafenib in Patients With Advanced Refractory Solid Tumors
Condition: Solid Tumors
Intervention: Drug: Lapatinib and Sorafenib
7 Completed Usefulness of Myocardial Deformation Imaging for Trastuzumab-induced Cardiotoxicity
Conditions: Left Ventricular Function Systolic Dysfunction;   Cardiotoxicity
8 Recruiting Vaccine Therapy in Treating Patients With Metastatic Solid Tumors
Conditions: Malignant Solid Tumour;   Breast Cancer;   Malignant Tumor of Colon;   GIST;   Ovarian Cancer
Intervention: Biological: HER-2 vaccine
9 Completed Treatment Options in Human Epidermal Growth Factor Receptor 2 (HER2) Positive Metastatic Breast Cancer Patients
Condition: Neoplasms, Breast
Intervention: Drug: Lapatinib plus capecitabine
10 Completed Human Epidermal Growth Factor Receptor 2 (HER2) Advanced Gastric Epidemiology Study in Korea
Condition: Gastric Cancer, Gastroesophageal Junction Cancer
11 Recruiting Ad/HER2/Neu Dendritic Cell Cancer Vaccine Testing
Conditions: Breast Neoplasms;   Breast Cancer;   Adenocarcinomas;   Metastatic Solid Tumors Characterized by HER2/Neu Expression
Intervention: Biological: Autologous Ad HER2 dendritic cell vaccine
12 Completed A Study of ARRY-380 in Patients With Advanced HER2+ Cancer
Condition: Cancer
Intervention: Drug: ARRY-380, HER2 inhibitor; oral
13 Not yet recruiting T Cells Expressing HER2-specific Chimeric Antigen Receptors(CAR) for Patients With Glioblastoma
Condition: Glioblastoma
Intervention: Genetic: HER2-specific T cells
14 Recruiting Her2 Chimeric Antigen Receptor Expressing T Cells in Advanced Sarcoma
Condition: Sarcoma
Interventions: Genetic: Autologous HER2-specific T cells;   Drug: Fludarabine;   Drug: Cyclophosphamide
15 Completed A Study to Test V930/V932 in Patients With Cancers Expressing Human Epidermal Growth Factor Receptor 2 (HER-2) and/or Carcinoembryonic Antigen (CEA)(V930-003)(COMPLETED)
Condition: Cancer
Interventions: Biological: V930;   Biological: V932
16 Recruiting Docetaxel, Carboplatin, Trastuzumab, and Pertuzumab With or Without Estrogen Deprivation in Treating Patients With Hormone Receptor-Positive, HER2-Positive Operable or Locally Advanced Breast Cancer
Conditions: Estrogen Receptor Positive;   HER2/Neu Positive;   Progesterone Receptor Positive;   Stage IB Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
Interventions: Drug: Aromatase Inhibition Therapy;   Drug: Carboplatin;   Other: Cytology Specimen Collection Procedure;   Drug: Docetaxel;   Drug: Goserelin Acetate;   Other: Laboratory Biomarker Analysis;   Biological: Pertuzumab;   Other: Quality-of-Life Assessment;   Procedure: Therapeutic Conventional Surgery;   Biological: Trastuzumab;   Radiation: Whole Breast Irradiation
17 Withdrawn Trastuzumab in Combination With AMG 479 in HER-2 Overexpressing MBC Progressing on Trastuzumab
Condition: Breast Cancer
Interventions: Drug: AMG 479;   Drug: Trastuzumab
18 Completed An Observational Study on HER2 Status of Breast Invasive Carcinoma in Latin American Participants
Condition: Breast Cancer
19 Recruiting Phase II Study of Eribulin Mesylate, Trastuzumab, and Pertuzumab in Women With Metastatic, Unresectable Locally Advanced, or Locally Recurrent HER2-Positive Breast Cancer
Condition: HER-2 Positive Breast Cancer
Intervention: Drug: Pertuzumab, Trastuzumab and Eribulin
20 Active, not recruiting CMV-specific Cytotoxic T Lymphocytes Expressing CAR Targeting HER2 in Patients With GBM
Condition: Glioblastoma Multiforme (GBM)
Intervention: Genetic: Genetically modified HER.CAR CMV-specific CTLs

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Indicates status has not been verified in more than two years