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4846 studies found for:    gene therapy
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Rank Status Study
1 Recruiting Gene Therapy for X-CGD
Condition: X-linked Chronic Granulomatous Disease
Intervention: Genetic: ex-vivo gene-therapy
2 Active, not recruiting EndocardialVascularEndothelialGrowth Factor D(VEGF-D)Gene Therapy for the Treatment of Severe Coronary Heart Disease
Conditions: Angina Pectoris;   Myocardial Infarction
Intervention: Biological: VEGF-D gene transfer
3 Not yet recruiting p53 Gene Therapy in Treatment of Diabetes Concurrent With Hepatocellular Carcinoma
Conditions: HCC;   Diabetes
Interventions: Drug: p53 gene therapy;   Drug: Trans-catheter embolization
4 Recruiting A Gene Therapy Study for Homozygous Familial Hypercholesterolemia (HoFH)
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Genetic: AAV directed hLDLR gene therapy
5 Not yet recruiting Effect of Intratumoral Injection of Gene Therapy for Locally Advanced Pancreatic Cancer
Condition: Pancreatic Adenocarcinoma
Interventions: Drug: Gene Therapy product CYL-02;   Drug: Gemcitabine
6 Recruiting Gene Transfer for Patients With Sickle Cell Disease
Conditions: Sickle Cell Disease;   Sickle Cell Anemia
Intervention: Genetic: Gene transfer
7 Completed Gene Therapy for ADA-SCID
Condition: Severe Combined Immunodeficiency Syndrome
Intervention: Genetic: gene transduced PBL and/or gene transduced HSC
8 Completed Gene Therapy of Pancreatic Ductal Adenocarcinoma
Condition: Pancreatic Adenocarcinoma
Intervention: Genetic: Gene Therapy product CYL-02 = plasmid DNA pre-complexed to linear polyethylenimine encoding sst2 + dck::umk genes
9 Active, not recruiting Gene Therapy for X-linked Severe Combined Immunodeficiency
Condition: X-linked Severe Combined Immunodeficiency
Intervention: Other: Gene transfer
10 Completed Gene Transfer Therapy for Treating Children and Adults With Limb Girdle Muscular Dystrophy Type 2D (LGMD2D)
Condition: Muscular Dystrophies
Interventions: Genetic: rAAV1.tMCK.human-alpha-sarcoglycan- First cohort;   Genetic: Genetic: rAAV1.tMCK.human-alpha-sarcoglycan- Second cohort
11 Recruiting Long-Term Follow-Up of Recipient of Gene Transfer Research
Conditions: Retroviridae Infections;   Cancer
Interventions: Other: Blood Tests;   Behavioral: Questionnaires
12 Recruiting Long Term Follow Up Of Patients Who Have Received Gene Therapy Or Gene Marked Products
Conditions: Severe Combined Immunodeficiency;   Malignancy, Hematologic;   Neuroblastoma;   Neoplasm;   Mucopolysaccharidosis I
Intervention: Procedure: Venipuncture
13 Withdrawn Quality of Life and Neuropsychiatric Sequelae in Patients Treated With Gene Therapy for ADA-SCID and in Their Parents
Condition: ADA-SCID
Intervention:
14 Recruiting Gene Transfer for Severe Combined Immunodeficiency, X-linked (SCID-X1) Using a Self-inactivating (SIN) Gammaretroviral Vector
Condition: Severe Combined Immunodeficiency
Intervention: Biological: Gene transfer
15 Completed Liver Transplantation With ADV-TK Gene Therapy Improves Survival in Patients With Advanced Hepatocellular Carcinoma
Conditions: Hepatocellular Carcinoma;   Liver Transplantation
Intervention: Genetic: ADV-TK (adenovirus-thymidine kinase enzyme) gene therapy
16 Active, not recruiting Gene Therapy for Wiskott-Aldrich Syndrome
Condition: Wiskott-Aldrich Syndrome
Intervention: Genetic: Autologous CD34 positive cells transduced with WAS encoding lentiviral vector.
17 Completed Clinical Study of AAV1-gamma-sarcoglycan Gene Therapy for Limb Girdle Muscular Dystrophy Type 2C
Conditions: Limb Girdle Muscular Dystrophy Type 2C;   Gamma-sarcoglycanopathy
Intervention: Biological: AAV1-gamma-sarcoglycan vector injection
18 Recruiting Study of Gene Therapy Using a Lentiviral Vector to Treat X-linked Chronic Granulomatous Disease
Condition: Granulomatous Disease, Chronic, X-linked
Intervention: Biological: Lentiviral G1XCGD Gene Therapy
19 Completed Gene Therapy ADA Deficiency
Condition: Adenosine Deaminase Deficiency
Intervention: Biological: Intravenous infusion of transduced cells
20 Completed Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-up
Conditions: Chronic Granulomatous Disease;   Communicable Disease
Interventions: Drug: Gene Therapy Method for CGD;   Device: Isolex 300i Magnetic Cell Selector

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Study has passed its completion date and status has not been verified in more than two years.