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4704 studies found for:    gene therapy
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Rank Status Study
21 Withdrawn Lentiviral Gene Therapy for X-Linked Chronic Granulomatous Disease (X-CGD)
Condition: Granulomatous Disease, Chronic, X-linked, Variant
Intervention: Genetic: pCCLchimGp91s lentiviral vector transduced CD34+ cells infusion
22 Completed Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-up
Conditions: Chronic Granulomatous Disease;   Communicable Disease
Interventions: Drug: Gene Therapy Method for CGD;   Device: Isolex 300i Magnetic Cell Selector
23 Recruiting Long Term Follow Up Of Patients Who Have Received Gene Therapy Or Gene Marked Products
Conditions: Severe Combined Immunodeficiency;   Malignancy, Hematologic;   Neuroblastoma;   Neoplasm;   Mucopolysaccharidosis I
Intervention: Procedure: Venipuncture
24 Completed Gene Therapy ADA Deficiency
Condition: Adenosine Deaminase Deficiency
Intervention: Biological: Intravenous infusion of transduced cells
25 Recruiting Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
Conditions: X-linked Severe Combined Immunodeficiency;   XSCID;   SCID-X1;   Gamma C-Deficient SCID
Interventions: Other: Gene-modified CD34+ Hematopoietic stem cells;   Drug: Busulfan
26 Recruiting Pilot and Feasibility Study of Hematopoietic Stem Cell Gene Transfer for the Wiskott-Aldrich Syndrome
Condition: Wiskott-Aldrich Syndrome
Intervention: Biological: Retrovirus-mediated gene transfer
27 Withdrawn Gene Therapy for Prostate Cancer That Returns After Radiation Therapy
Conditions: Prostatic Neoplasms;   Neoplasm Recurrence, Local
Intervention: Genetic: Ad.hIL-12
28 Recruiting Gene Therapy for WAS
Condition: Wiskott-Aldrich Syndrome
Intervention: Genetic: Autologous CD34 positive cells transduced with a lentiviral vector containing human WAS gene
29 Active, not recruiting ADA Gene Transfer Into Hematopoietic Stem/Progenitor Cells for the Treatment of ADA-SCID
Condition: Immunologic Deficiency Syndromes
Intervention: Genetic: Gene transduced CD34+ cells
30 Completed
Has Results
Randomized Trial of Suicide Gene Therapy and Prostate Cancer
Condition: Prostate Cancer
Interventions: Biological: Ad5-yCD/mutTKSR39rep-ADP;   Radiation: IMRT
31 Recruiting Gene Therapy for Wiskott-Aldrich Syndrome (WAS)
Condition: Wiskott-Aldrich Syndrome
Intervention: Genetic: Autologous CD34 positive cells transduced with a lentiviral vector containing human WAS gene
32 Completed Gene Therapy in Treating Patients With Primary Brain Tumors
Condition: Brain and Central Nervous System Tumors
Interventions: Biological: gene therapy;   Drug: chemotherapy;   Drug: ganciclovir;   Procedure: conventional surgery
33 Recruiting Gene Therapy for X-linked Severe Combined Immunodeficiency (SCID-X1)
Condition: X-linked Severe Combined Immunodeficiency
Intervention: Genetic: Single infusion of autologous CD34+ cells transduced with the self-inactivating (SIN) gammaretroviral vector pSRS11.EFS.IL2RG.pre
34 Terminated Gene Therapy for Chronic Granulomatous Disease
Condition: Chronic Granulomatous Disease
Intervention: Drug: Phagocyte Oxidase Subunit Transduced CD34 Hematopoietic Stem Cells
35 Active, not recruiting Open-Label Single Ascending Dose of Adeno-associated Virus Serotype 8 Factor IX Gene Therapy in Adults With Hemophilia B
Condition: Hemophilia B
Intervention: Biological: AskBio009
36 Completed Gene Therapy for Gyrate Atrophy
Condition: Gyrate Atrophy
Intervention: Procedure: Gene therapy
37 Completed Follow-up of Breast Cancer and Multiple Myeloma Patients Previously Enrolled in NIH Gene Therapy Studies
Condition: Gene Transfer
Intervention:
38 Enrolling by invitation Long-term Follow-up of Subjects With Hemoglobinopathies Treated With Ex Vivo Gene Therapy
Conditions: Beta-Thalassemia;   Sickle Cell Disease
Intervention: Other: Safety and efficacy assessments
39 Active, not recruiting Gene Therapy for Metachromatic Leukodystrophy
Condition: Metachromatic Leukodystrophy
Intervention: Genetic: Autologous CD34+ stem cells transduced with ARSA encoding lentiviral vector
40 Terminated Suicide Gene Therapy Trial
Condition: Haploidentical Stem Cell Transplantation
Intervention: Biological: HSVTK retrovirally-transduced donor T lymphocytes

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Indicates status has not been verified in more than two years