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4846 studies found for:    gene therapy
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Rank Status Study
21 Withdrawn Lentiviral Gene Therapy for X-Linked Chronic Granulomatous Disease (X-CGD)
Condition: Granulomatous Disease, Chronic, X-linked, Variant
Intervention: Genetic: pCCLchimGp91s lentiviral vector transduced CD34+ cells infusion
22 Active, not recruiting ADA Gene Transfer Into Hematopoietic Stem/Progenitor Cells for the Treatment of ADA-SCID
Condition: Immunologic Deficiency Syndromes
Intervention: Genetic: Gene transduced CD34+ cells
23 Active, not recruiting Open-Label Single Ascending Dose of Adeno-associated Virus Serotype 8 Factor IX Gene Therapy in Adults With Hemophilia B
Condition: Hemophilia B
Intervention: Biological: AskBio009
24 Completed Gene Therapy for Alzheimer's Disease Clinical Trial
Condition: Alzheimer Disease
Intervention: Genetic: Human Nerve Growth Factor
25 Completed Follow-up of Breast Cancer and Multiple Myeloma Patients Previously Enrolled in NIH Gene Therapy Studies
Condition: Gene Transfer
Intervention:
26 Active, not recruiting Gene Therapy for X-linked Severe Combined Immunodeficiency (SCID-X1)
Condition: X-linked Severe Combined Immunodeficiency
Intervention: Genetic: Single infusion of autologous CD34+ cells transduced with the self-inactivating (SIN) gammaretroviral vector pSRS11.EFS.IL2RG.pre
27 Unknown  Surgery Combined With rAd-p53 Gene in Treatment Advanced Non-small-cell Carcinoma
Condition: Non-small Cell Lung Cancer
Interventions: Drug: Surgery combined with rAd-p53 gene therapy;   Procedure: Surgery
28 Recruiting Pilot and Feasibility Study of Hematopoietic Stem Cell Gene Transfer for the Wiskott-Aldrich Syndrome
Condition: Wiskott-Aldrich Syndrome
Intervention: Biological: Retrovirus-mediated gene transfer
29 Active, not recruiting Choroideremia Gene Therapy Clinical Trial
Condition: Choroideremia
Intervention: Genetic: Injection of AAV2-REP1 (10e11 vg)
30 Active, not recruiting Gene Therapy for Metachromatic Leukodystrophy
Condition: Metachromatic Leukodystrophy
Intervention: Genetic: Autologous CD34+ stem cells transduced with ARSA encoding lentiviral vector
31 Enrolling by invitation Follow-Up Evaluation for Gene-Therapy-Related Delayed Adverse Events After Participation in Pediatric Oncology Branch Clinical Trials
Conditions: Pediatric Cancers;   Hematologic Malignancies;   Solid Tumors
Intervention:
32 Recruiting Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
Conditions: X-linked Severe Combined Immunodeficiency;   XSCID;   SCID-X1;   Gamma C-Deficient SCID
Interventions: Other: Gene-modified CD34+ Hematopoietic stem cells;   Drug: Busulfan
33 Terminated Study Combining Suicide Gene Therapy With Chemoradiotherapy in the Treatment of Non-Metastatic Pancreatic Adenocarcinoma
Condition: Pancreatic Cancer
Intervention: Genetic: Ad5-yCD/mutTKSR39rep-ADP
34 Withdrawn Isolated Limb Infusion Chemotherapy With Targeted Gene Therapy for Advanced, Unresectable Extremity Melanoma
Condition: Melanoma
Interventions: Biological: dactinomycin;   Drug: melphalan;   Biological: Conditionally replicative adenovirus 3/5-delta
35 Recruiting Gene Therapy for WAS
Condition: Wiskott-Aldrich Syndrome
Intervention: Genetic: Autologous CD34 positive cells transduced with a lentiviral vector containing human WAS gene
36 Recruiting Gene Therapy for WAS Follow-up
Condition: Wiskott-Aldrich Syndrome
Intervention: Genetic: Autologous CD34+ cells transduced with WASP lentiviral vector
37 Completed Gene Therapy for Gyrate Atrophy
Condition: Gyrate Atrophy
Intervention: Procedure: Gene therapy
38 Completed
Has Results
Randomized Trial of Suicide Gene Therapy and Prostate Cancer
Condition: Prostate Cancer
Interventions: Biological: Ad5-yCD/mutTKSR39rep-ADP;   Radiation: IMRT
39 Completed Gene Therapy Plus Chemotherapy in Treating Patients With Breast Cancer
Condition: Breast Cancer
Interventions: Biological: Ad5CMV-p53 gene;   Drug: chemotherapy
40 Recruiting Study of RS1 Ocular Gene Transfer for X-linked Retinoschisis
Condition: Gene Transfer
Intervention: Biological: RS1 AAV Vector

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Study has passed its completion date and status has not been verified in more than two years.