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78 studies found for:    fusion gene cancer
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Rank Status Study
1 Recruiting Pioglitazone in Thyroid Cancers
Condition: Thyroid Cancers That Contain the PAX8-PPARgamma Fusion Gene
Intervention: Drug: Pioglitazone
2 Active, not recruiting Analyze the Predictive Value of Gene TMPRSS2-ETS in Response to Enzalutamide in Patients With Prostate Cancer
Condition: Hormone-refractory Prostate Cancer
Intervention: Drug: Enzalutamide
3 Active, not recruiting Phase 1 Study of DS-6051b in Japanese Subjects With Advanced Solid Malignant Tumors
Condition: Advanced Solid Malignant Tumors
Intervention: Drug: DS-6051b
4 Recruiting Study of Apatinib in RET Fusion Positive Advanced Non-small Cell Lung Cancer
Condition: Non-small Cell Lung Cancer
Intervention: Drug: Apatinib single agent arm
5 Suspended WT1 Immunity Via DNA Fusion Gene Vaccination in Haematological Malignancies by Intramuscular Injection Followed by Intramuscular Electroporation
Conditions: Leukaemia (Acute);   Leukaemia (Chronic);   Leukaemia (Acute Myeloid);   Leukaemia (Acute Lymphoblastic);   Leukaemia (Acute Promyelocytic)
Intervention: Biological: p.DOM-WT1-37 DNA Vaccine and p.DOM-WT1-126 DNA Vaccine
6 Completed Therapy of HES, PV, Atypical Chronic Myelocytic Leukemia (CML) or Chronic Myelomonocytic Leukemia (CMML), and Mastocytosis With Imatinib Mesylate
Conditions: Chronic Myelomonocytic Leukemia;   Chronic Myeloid Leukemia;   Polycythemia Vera;   Hypereosinophilic Syndrome;   Mastocytosis
Intervention: Drug: Imatinib Mesylate (Gleevec)
7 Recruiting A Retrospective Pharmacogenomics Research of EGFR-TKIs,Gefitinib and Erlotinib, in Non-small Cell Lung Cancer(NSCLC)Treatment
Conditions: Non-small Cell Lung Cancer (NSCLC);;   EGFR-TKI Resistant Mutation;;   EGFR-TKI Sensitizing Mutation;;   Germline Mutations
Intervention:
8 Unknown  A Retrospective Study of Biomarkers in Non-Small Cell Lung Cancer
Condition: Non Small Cell Lung Cancer
Intervention:
9 Recruiting Endodrill vs. Conventional Biopsy. Diagnostics and Genetic Analysis
Condition: Esophageal Neoplasm
Interventions: Device: Endodrill Biopsy;   Device: Conventional Biopsy forceps
10 Completed Diagnostic Study of Tumor Characteristics in Patients With Ewing's Sarcoma
Conditions: Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Intervention: Other: laboratory biomarker analysis
11 Active, not recruiting Studying Tissue and Blood Samples From Patients With Acute Myeloid Leukemia
Condition: Leukemia
Interventions: Genetic: DNA analysis;   Genetic: DNA methylation analysis;   Genetic: gene expression analysis;   Genetic: mutation analysis;   Genetic: polymerase chain reaction;   Genetic: reverse transcriptase-polymerase chain reaction;   Other: high performance liquid chromatography;   Other: laboratory biomarker analysis
12 Recruiting The Predictive Value of Coexisting TMPRSS2-ERG Gene Fusion and PTEN Deletion in Prostate Cancer Patients With Biochemical Failure Status Post Salvage or Radical Radiation Therapy
Condition: Prostate Cancer
Intervention:
13 Available Expanded Access to Entrectinib for Cancers With NTRK1/2/3, ROS1, or ALK Gene Fusions
Condition: Cancers With NTRK, ROS1, or ALK Gene Fusions
Intervention: Drug: Entrectinib
14 Available Expanded Access to Provide Larotrectinib (LOXO-101) for the Treatment of Cancers With a NTRK Gene Fusion
Conditions: Cancer;   Neurotrophic Tyrosine Kinase, Receptor-related Proteins
Intervention: Drug: larotrectinib
15 Recruiting Pbi-shRNA™ EWS/FLI1 Type 1 LPX in Subjects With Advanced Ewing's Sarcoma
Condition: Ewing's Sarcoma
Intervention: Biological: pbi-shRNA™ EWS/FLI1 Type 1 LPX
16 Recruiting Treatment With AZD4547 for Recurrent Malignant Glioma Expressing FGFR-TACC Gene Fusion"
Conditions: Recurrent IDHwt Gliomas With FGFR3-TACC3 Fusion;   Recurrent IDHwt Gliomas With FGFR1-TACC1 Fusion
Intervention: Drug: AZD4547
17 Recruiting Assessing DNA Changes in High Risk Prostate Cancer to Determine Prognosis
Condition: Prostate Cancer
Intervention:
18 Completed Study of Intra-articular Delivery of tgAAC94 in Inflammatory Arthritis Subjects
Conditions: Arthritis, Rheumatoid;   Arthritis, Psoriatic;   Ankylosing Spondylitis
Interventions: Genetic: tgAAC94 gene therapy vector;   Genetic: tgAAC94 placebo
19 Not yet recruiting The Predictive Value of TMPRSS2-ERG Fusion in High Risk Prostate Cancer Patient
Condition: Prostate Cancer
Intervention: Drug: LHRH therapy
20 Recruiting Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)
Conditions: Breast Cancer;   Cholangiocarcinoma;   Colorectal Cancer;   Head and Neck Neoplasms;   Lymphoma, Large-Cell, Anaplastic;   Melanoma;   Neuroendocrine Tumors;   Non-Small Cell Lung Cancer;   Ovarian Cancer;   Pancreatic Cancer;   Papillary Thyroid Cancer;   Primary Brain Tumors;   Renal Cell Carcinoma;   Sarcomas;   Salivary Gland Cancers;   Adult Solid Tumor
Intervention: Drug: Entrectinib

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Study has passed its completion date and status has not been verified in more than two years.