| 101 |
NCT03626623 |
Not yet recruiting
New |
Diabetic Foot Ulcer Study Comparing Cytal Wound Matrix 1-Layer to Standard of Care |
- Diabetes
- Diabetic Foot
- Diabetes Mellitus, Type 2
- Diabetes Mellitus, Type 1
|
- Device: Cytal Wound Matrix 1-Layer
- Other: Standard of Care (SOC)
|
Interventional
|
Not Applicable |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Incidence of Wound Closure
- Wound Size Change
- Complete Wound Closure Time
- (and 12 more...)
|
150 |
All |
21 Years and older (Adult, Older Adult) |
NCT03626623 |
CR2017-06 |
|
September 2018 |
September 2019 |
September 2020 |
August 13, 2018 |
August 13, 2018 |
|
- Louisiana State University Health Science Center (LSUHSC)
New Orleans, Louisiana, United States - University Hospital
Newark, New Jersey, United States - University of Pittsburgh Medical Center (UPMC)
Pittsburgh, Pennsylvania, United States
|
|
| 102 |
NCT01645891 |
Completed |
A Prospective, Randomized, Double-Blind Multicenter Study Comparing Continuous Diffusion of Oxygen (CDO) Therapy to Standard Moist Wound Therapy (MWT) in the Treatment of Diabetic Foot Ulcers |
|
- Device: CDO electrochemical tissue oxygenation system
- Device: Moist Wound Therapy
|
Interventional
|
Not Applicable |
- Electrochemical Oxygen Concepts, Inc.
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Complete (100%) wound closure defined as complete re-epithelialization without drainage
- Time to 50%, 75% and 100% wound closure
- Pain Reduction
- (and 4 more...)
|
146 |
All |
30 Years to 90 Years (Adult, Older Adult) |
NCT01645891 |
TC02-2012-01 |
|
April 2012 |
November 2016 |
November 2016 |
July 20, 2012 |
February 9, 2017 |
|
- Clinical Trials of Texas, Inc., dba Clinical Trials of Arizona, Inc.
Glendale, Arizona, United States - Associated Foot and Ankle Specialists
Phoenix, Arizona, United States - Southern Arizona VA Health Care System
Tucson, Arizona, United States - (and 22 more...)
|
|
| 103 |
NCT03321721 |
Recruiting |
Cosmetic Outcome at 4 Months in Hand and Feet Lacerations in Children: Conservative Versus Suture Repair |
- Laceration Repair, Children
- Hand Injuries
- Foot Injuries
|
- Other: Suture (nylon) for wound repair
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Cosmetic outcome of hand and feet laceration in children : conservative vs suture repair
|
80 |
All |
2 Years to 17 Years (Child) |
NCT03321721 |
IRB 26912 |
|
April 13, 2014 |
June 2020 |
June 2020 |
October 26, 2017 |
July 6, 2018 |
|
- cardinal glennon children's hospital / Division of Emergency Medicine
Saint Louis, Missouri, United States
|
|
| 104 |
NCT01849965 |
Terminated |
Phase 3 Study Evaluating Efficacy and Safety of DSC127 Compared With Vehicle and With Standard-of-care in Diabetic Foot Ulcers |
|
- Drug: DSC127
- Drug: placebo vehicle gel
- Drug: Standard of Care gel, Aquasite
|
Interventional
|
Phase 3 |
- Integra LifeSciences Corporation
- Integrium
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- The proportion of subjects with a target ulcer which achieves complete wound closure by 10 weeks (confirmed 2 weeks later) after initiation of treatment.
- The proportion of subjects with a target ulcer which achieves complete wound closure by 10 weeks (confirmed two weeks later) after initiation of treatment.
|
396 |
All |
18 Years and older (Adult, Older Adult) |
NCT01849965 |
DSC127-2012-02 |
STRIDE 2 |
April 2013 |
December 2015 |
December 2015 |
May 9, 2013 |
December 12, 2017 |
|
- East Valley Foot and Ankle Specialist
Mesa, Arizona, United States - Arizona Burn Center Maricopa Medical Center
Phoenix, Arizona, United States - Associated Foot & Ankle Specialists, PC
Phoenix, Arizona, United States - (and 53 more...)
|
|
| 105 |
NCT03476876 |
Recruiting |
Comparative Effectiveness of Two Acellular Matrices (Dermacell vs. Integra) for Management of Deep Diabetic Foot Ulcers |
- Diabetic Foot Ulcer
- Deep Diabetic Foot Ulcer
|
- Device: Dermacell
- Device: Integra
|
Interventional
|
Phase 2
Phase 3 |
- Baylor College of Medicine
- LifeNet Heath
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- wound size change from Baseline to 8 weeks and 16 weeks
- Time to reach successful granulation from baseline to 16 weeks
- Incidence of complication from baseline to 16 weeks
- (and 5 more...)
|
50 |
All |
18 Years and older (Adult, Older Adult) |
NCT03476876 |
H-42282 |
|
April 2, 2018 |
March 15, 2020 |
June 15, 2020 |
March 26, 2018 |
July 12, 2018 |
|
- Baylor College of Medicine
Houston, Texas, United States
|
|
| 106 |
NCT03458286 |
Not yet recruiting |
A Study Measuring the Effectiveness of Combined Modulated Ultrasound and Electric Current Stimulation as an Adjunctive Treatment in Treating Diabetic Foot Ulcers |
|
- Device: BRH-A2 wound healing device
|
Interventional
|
Not Applicable |
- Royal College of Surgeons, Ireland
- Jagmed Limited
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Total wound healing
- Changes in wound bed condition.
- Patient reported quality of life
- (and 5 more...)
|
50 |
All |
18 Years and older (Adult, Older Adult) |
NCT03458286 |
DFUCUSECS |
|
April 2018 |
September 2018 |
October 2018 |
March 8, 2018 |
March 8, 2018 |
|
|
|
| 107 |
NCT02161016 |
Terminated
Has Results |
A Clinical Study of Outcomes in Foot and Ankle Bone Grafting Using map3® Cellular Allogeneic Bone Graft |
- Foot Deformities, Acquired
- Disorder of Joint of Foot
- Fracture of Foot
- Deformity of Bone
|
|
Interventional
|
Phase 4 |
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- AOFAS Foot-and-Ankle Score
- SF-36 Score
- Foot Ankle Disability Index
- CT Scan
|
1 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT02161016 |
map3-2014 |
|
June 2014 |
January 2015 |
January 2015 |
June 11, 2014 |
April 1, 2015 |
April 1, 2015 |
- Saint Francis Hospital
Roslyn, New York, United States
|
|
| 108 |
NCT01221207 |
Unknown † |
Instant Total Contact Cast to Heal Diabetic Foot Ulcers |
|
- Device: Total Contact Cast
- Device: Instant Total Contact Cast (ITCC)
- Device: Removable Cast Walker (RCW)
|
Interventional
|
Not Applicable |
- University of Texas Southwestern Medical Center
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- Wound Evaluation and Healing: The lower extremity evaluation will include length, width, depth, and area of the ulcer before and after debridement.
- Evaluation of Complications: At each visit the study nurse will interview patients and determine if they have experienced any adverse events.
|
225 |
All |
18 Years and older (Adult, Older Adult) |
NCT01221207 |
UTSW - 7R01DK074483-04 |
ITCC |
October 2010 |
October 2012 |
October 2012 |
October 14, 2010 |
October 18, 2010 |
|
- University of Arizona
Tucson, Arizona, United States - Parkland Health & Hospital Systems
Dallas, Texas, United States - UT Southwestern Medical Center at Dallas
Dallas, Texas, United States - Scott & White
Temple, Texas, United States
|
|
| 109 |
NCT00820703 |
Terminated |
The ASCEND Study: A Study to Investigate the Safety and Clinical Effect of Nexagon to Treat Slow Healing Diabetic Foot Ulcers |
|
- Drug: Nexagon®
- Drug: Nexagon® vehicle
|
Interventional
|
Phase 1
Phase 2 |
- OcuNexus Therapeutics, Inc.
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double
- Primary Purpose: Treatment
|
- To evaluate the safety and clinical effect of Nexagon® administered topically to diabetic foot ulcers.
- To select the optimal dose(s) which can be used in future trials of Nexagon® in diabetic foot ulcers
- To pilot the collection of data that may be considered useful in planning future studies of Nexagon® administered topically to diabetic foot ulcers.
|
24 |
All |
18 Years and older (Adult, Older Adult) |
NCT00820703 |
NEX-ULC-003 |
|
April 2009 |
November 2009 |
December 2009 |
January 12, 2009 |
August 31, 2010 |
|
- Middlemore Hospital
Auckland, New Zealand
|
|
| 110 |
NCT03137966 |
Not yet recruiting |
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers |
|
- Drug: Deferoxamine
- Drug: Placebo
|
Interventional
|
Phase 2 |
- Karolinska University Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Healing
- Improvement of ulcer
|
174 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT03137966 |
170428-DEFEHU |
DEFEHU |
November 30, 2018 |
December 31, 2022 |
December 31, 2022 |
May 3, 2017 |
August 9, 2018 |
|
|
|
| 111 |
NCT03254095 |
Enrolling by invitation |
Predictors of Skin Temperature, Plantar Pressure and Ulceration in Diabetic Foot Patients. |
|
|
Observational
|
|
- Universidade do Porto
- Centro Hospitalar do Porto
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Skin temperature
- Barefoot plantar pressure
- Percentage of patients developing a foot ulcer
- (and 5 more...)
|
100 |
All |
18 Years and older (Adult, Older Adult) |
NCT03254095 |
FADEUP_PhD_AdéritoSeixas#1 |
|
September 1, 2016 |
May 31, 2017 |
September 30, 2018 |
August 18, 2017 |
May 17, 2018 |
|
|
|
| 112 |
NCT02432170 |
Completed |
Weight-Bearing Tomosynthesis In Evaluation of Foot/AnkIe |
|
- Device: Digital Tomosynthesis of Foot and Ankle
|
Interventional
|
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Severity of Arthritis (assessed through reading radiologic images and through a pain survey)
|
47 |
All |
18 Years and older (Adult, Older Adult) |
NCT02432170 |
48992 |
|
April 2015 |
April 2017 |
April 2017 |
May 4, 2015 |
October 26, 2017 |
|
- University of Washington
Seattle, Washington, United States
|
|
| 113 |
NCT01389362 |
Completed |
The Healing Effect of a Two-Herb Recipe on Foot Ulcer in Chinese Patients With Type 2 Diabetes |
|
- Drug: Chinese herbal medicine (Radix Rehmanniae and Radix Astragali)
- Drug: Placebo comparator
|
Interventional
|
Phase 2
Phase 3 |
- Chinese University of Hong Kong
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Resolution/progression of foot ulcer based on PEDIS
- Hospital admission/attendance/stay
|
16 |
All |
20 Years to 75 Years (Adult, Older Adult) |
NCT01389362 |
CRE-2008.581 |
|
May 2009 |
May 2011 |
May 2011 |
July 8, 2011 |
July 28, 2011 |
|
- Diabetes and Endocrine Centre
Hong Kong SAR, Hong Kong SAR, China
|
|
| 114 |
NCT03408236 |
Recruiting |
Evaluate the Safety and Efficacy of Botulax® as Compared to Botox® in Subject With Moderate to Severe Crow's Feet Lines |
|
- Drug: Botulinum toxin type A
|
Interventional
|
Phase 3 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Facial Wrinkle Scale(FWS) severity of crow's feet lines(CFL) at maxium smile as assessed by investigators
|
240 |
All |
19 Years to 65 Years (Adult, Older Adult) |
NCT03408236 |
HG-BOTCFL-III1 |
|
September 11, 2017 |
June 30, 2018 |
August 30, 2018 |
January 23, 2018 |
January 26, 2018 |
|
- Hugel
Seoul, Korea, Republic of
|
|
| 115 |
NCT01816672 |
Terminated |
Efficacy of AutoloGel Therapy to Usual and Customary Care in Wagner gd 1 and 2 Diabetic Foot Ulcers. |
|
- Device: AutoloGel
- Other: Usual and Customary Care
|
Interventional
|
Not Applicable |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Compare time to heal in Wagner 1 and 2 diabetic foot ulcers at 12 weeks treated with AutoloGel versus usual and customary care
- Assess wound healing trajectory and change in Chronic Wound quality of Life W-QOL scores: and to assess the comparative safety of AutoloGel and usual and customary care
- Number of patients with adverse events as a measure of tolerability
|
4 |
All |
18 Years and older (Adult, Older Adult) |
NCT01816672 |
CM001 |
|
April 2013 |
July 2015 |
July 2015 |
March 22, 2013 |
October 21, 2016 |
|
- Forest General Hospital
Hattiesburg, Mississippi, United States
|
|
| 116 |
NCT02353273 |
Completed |
The Pharmacokinetic Study of WH-1 Ointment in Subjects With Chronic Diabetic Foot Ulcers |
|
|
Interventional
|
Phase 1 |
- Oneness Biotech Co., Ltd.
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Pharmacokinetic parameters of Salvigenin and Asiaticoside A as listed below. (AUC0-∞, AUC0-t, Cmax)(Cmax,ss, AUC0-τ)
- Pharmacokinetic parameters of Salvigenin and Asiaticoside A as listed below, if appropriate. (Tmax, MRT, T1/2, Vd/F, CL/F)
- Pharmacokinetic parameters of Salvigenin and Asiaticoside A as listed below, if appropriate. (Tmax,ss)
|
12 |
All |
20 Years and older (Adult, Older Adult) |
NCT02353273 |
ON101CLPK01 |
|
July 22, 2015 |
July 5, 2016 |
September 5, 2016 |
February 2, 2015 |
March 29, 2018 |
|
- Clinical Research Division
Taipei, Taiwan
|
|
| 117 |
NCT02619877 |
Completed |
Clinical Study to Evaluate Efficacy and Safety of ALLO-ASC-DFU in Patients With Diabetic Foot Ulcers |
|
- Biological: ALLO-ASC-DFU
- Other: Standard therapy
|
Interventional
|
Phase 2 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Proportion of re-epithelialization
- Time to re-epithelialization
- Number of Participants with Adverse Events as a Measure of Safety and Tolerability
|
59 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT02619877 |
ALLO-ASC-DFU-201 |
|
October 2015 |
September 2016 |
October 2016 |
December 2, 2015 |
September 1, 2017 |
|
- Korea University Guro Hospital
Guro-gu, Seoul, Korea, Republic of - Eulji General Hospital
Nowon-Gu, Seoul, Korea, Republic of - Severance Hospital
Seodaemun-Gu, Seoul, Korea, Republic of - Asan medical center
Songpa-Gu, Seoul, Korea, Republic of
|
|
| 118 |
NCT03170687 |
Recruiting |
Comparative Outcomes Between Foot Cast and Short Leg Cast in the Patients With Acute Closed Fracture of Proximal Fifth Metatarsal (Zone II) |
- Acute Closed Fracture of Proximal Fifth Metatarsal (Zone II)
|
- Device: short foot cast
- Device: short leg cast
|
Interventional
|
Not Applicable |
- Jatupon Kongtharvonskul
- Police General Hospital
- Ramathibodi Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- VAS
- AOFAS
- union rate
- complication
|
100 |
All |
15 Years and older (Child, Adult, Older Adult) |
NCT03170687 |
53/2560 |
|
January 24, 2017 |
January 2019 |
January 2019 |
May 31, 2017 |
May 31, 2017 |
|
- Jatupon Kongtharvonskul
Bangkok, Select..., Thailand
|
|
| 119 |
NCT02727348 |
Completed |
Sciatic Nerve Blocks With or Without Femoral Block Versus Spinal Anaesthesia in Patients Undergoing Diabetic Foot Surgery |
|
- Procedure: Sciatic with or without femoral block
- Procedure: Spinal anaesthesia
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Care Provider)
- Primary Purpose: Treatment
|
- Blood pressure or heart rate changes more than 30% of baseline after spinal or block is considered significant
- S-LANSS score in who receive FSNB versus SAB.
|
120 |
All |
18 Years to 99 Years (Adult, Older Adult) |
NCT02727348 |
201401-0658 |
|
May 2014 |
January 2016 |
February 2016 |
April 4, 2016 |
April 4, 2016 |
|
- University Malaya Medical Centre
Kuala Lumpur, Malaysia
|
|
| 120 |
NCT01839669 |
Terminated |
The CurePPaC Study - Analysing Non-surgical Treatment Strategies to Cure Pes Planovalgus Associated Complaints |
- Foot Injuries
- Posterior Tibial Tendon Dysfunction
|
- Device: Foot Orthoses Only
- Procedure: Foot Orthoses and Eccentric Exercise
- Device: Sham Foot Orthoses
|
Interventional
|
Not Applicable |
- Bern University of Applied Sciences
- Swiss National Science Foundation
- University Hospital Inselspital, Berne
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Foot Function Index - total score
- Foot Function Index - subcategory pain
- Foot Function Index - subcategory disability
- Foot Function Index - subcategory activity limitation
|
7 |
All |
18 Years to 60 Years (Adult) |
NCT01839669 |
140928 |
|
July 2013 |
October 25, 2017 |
October 25, 2017 |
April 25, 2013 |
October 27, 2017 |
|
- Spital Netz Bern Ziegler
Bern, Switzerland - Klinik Sonnenhof Bern
Bern, Switzerland - Inselspital, University Hospital Bern
Bern, Switzerland - (and 3 more...)
|
|
| 121 |
NCT03411187 |
Recruiting |
Study on the Application of Convenient Foot-control Exhaust Method in Endoscopic Thyroidectomy |
- Thyroid Cancer
- Papillary Thyroid Carcinoma
- Thyroidectomy
- Endoscopy
|
- Device: used of the Pressure adjustable foot-control method
- Device: direct exhaust
|
Interventional
|
Not Applicable |
- Bo Wang,MD
- Fujian Medical University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Flap separation time
- Glandular excision time
- Central lymph node dissection time
- (and 6 more...)
|
100 |
All |
18 Years to 70 Years (Adult, Older Adult) |
NCT03411187 |
exhaust |
|
January 1, 2018 |
June 30, 2018 |
June 30, 2018 |
January 26, 2018 |
April 27, 2018 |
|
- Wen-xin ZHAO
Fuzhou, Fujian, China
|
|
| 122 |
NCT02632877 |
Completed |
Efficacy of Pirfenidone Plus MODD in Diabetic Foot Ulcers |
|
- Drug: Pirfenidone with MODD
- Drug: Ketanserin
|
Interventional
|
Phase 1
Phase 2 |
- University of Guadalajara
- Cell Pharma, SA de CV
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- assessing change of ulcerated area
- mRNA levels of collagen type I alpha (COL-1a)
- mRNA levels of Transforming growth factor 1-beta (TGFb-1)
- (and 7 more...)
|
60 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT02632877 |
IBMMTG.14
ISSSTE/CEI/TR/2014/01
Institute of Molecular Biology |
|
January 2014 |
November 2015 |
December 2015 |
December 17, 2015 |
December 17, 2015 |
|
- Molecular Biology and Gene Therapy Institute
Guadalajara, Jalisco, Mexico - Hospital Valentín Gómez Farías
Zapopan, Jalisco, Mexico
|
|
| 123 |
NCT02902211 |
Recruiting |
Improving Mobility in Peripheral Artery Disease Using an Ankle Foot Orthosis |
- Peripheral Artery Disease
|
- Device: Ankle foot orthosis
- Other: Control/standard of care
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Maximum walking distance from the Gardner graded treadmill protocol.
|
50 |
All |
40 Years to 85 Years (Adult, Older Adult) |
NCT02902211 |
485-16-FB |
|
July 7, 2017 |
April 2022 |
April 2022 |
September 15, 2016 |
September 29, 2017 |
|
- Omaha VA Medical Center
Omaha, Nebraska, United States
|
|
| 124 |
NCT02652754 |
Completed |
Safety Study to Examine the Systemic Exposure of Granexin® Gel After Topical Application to Diabetic Foot Ulcers |
|
|
Interventional
|
Phase 1 |
- FirstString Research, Inc.
- Medical University of South Carolina
- Spartanburg Regional Healthcare System
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Measurement of aCT1 peptide (Active Pharmaceutical Ingredient in Granexin) levels in blood
|
16 |
All |
18 Years and older (Adult, Older Adult) |
NCT02652754 |
DFU-PK-300 |
|
September 2015 |
December 2017 |
May 2018 |
January 12, 2016 |
August 1, 2018 |
|
- Aiyan Diabetes Center
Augusta, Georgia, United States - Spartanburg Regional Healthcare System
Spartanburg, South Carolina, United States - Salem VA Medical Center
Salem, Virginia, United States
|
|
| 125 |
NCT03153007 |
Completed |
Study of Subjects With Diabetic Foot Ulcer (DFU) |
|
|
Observational
|
|
|
Industry |
- Observational Model: Case-Only
- Time Perspective: Cross-Sectional
|
- Assessment of signs and symptoms, impacts on functioning and HRQoL among subjects with DFU
|
1 |
All |
18 Years and older (Adult, Older Adult) |
NCT03153007 |
207650 |
|
August 11, 2017 |
December 6, 2017 |
December 6, 2017 |
May 15, 2017 |
January 18, 2018 |
|
- GSK Investigational Site
Bethesda, Maryland, United States
|
|
| 126 |
NCT00909883 |
Unknown † |
Foot Dystonia Treatment by Botulinum Toxin Injections in Parkinson Disease : Efficiency of Injections Made in Extrinsic Muscle (Flexor Digitorum Longus Muscle) Compared to Intrinsic Muscle (Flexor Digitorum Brevis or Quadratus Plantae Muscles) |
- Parkinson's Disease
- Foot Dystonia
|
- Drug: Botulinum Toxin: Xeomin
- Drug: Placebo
|
Interventional
|
Phase 3 |
- University Hospital, Clermont-Ferrand
- Merz Pharmaceuticals
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- In a controlled double blind and randomized study, we want to show that intramuscular injections of botulinum toxin are beneficial to reduced dystonia and associated pain in patient with foot dystonia (compared to placebo injections).
- Efficiency comparison of injections made in leg muscle (Flexor digitorum longus) between injections made directly in foot muscle (Flexor digitorum brevis or quadratus plantae) - Effects of injections on pain and quality of life.
|
45 |
All |
30 Years to 75 Years (Adult, Older Adult) |
NCT00909883 |
CHU-0051 |
RBHP 2008 |
September 2009 |
September 2011 |
September 2012 |
May 29, 2009 |
March 25, 2011 |
|
- CHU Gabriel-Montpied
Clermont-Ferrand, France - Hôpital La Pitié Salpétrière
Paris, France - Hôpital Haut-Levêque
Pessac, France - CHU Purpan
Toulouse, France
|
|
| 127 |
NCT01418456 |
Unknown † |
Outcomes of Non-infected Diabetic Foot Ulcers With/Without Antibiotics |
- Diabetes
- Foot Ulcers
- Infection
|
|
Interventional
|
Phase 4 |
- King's College Hospital NHS Trust
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: Single (Care Provider)
- Primary Purpose: Treatment
|
- Time to healing of foot ulceration in each group
- • Percentage of patients who will develop clinical signs of infection over a follow up period of 20 weeks
- • Percentage of patients in each group that are healed at 20 weeks.
|
166 |
All |
18 Years to 85 Years (Adult, Older Adult) |
NCT01418456 |
KADFUT
2010-022518-16 |
KADFUT |
August 2011 |
February 2012 |
February 2012 |
August 17, 2011 |
August 17, 2011 |
|
|
|
| 128 |
NCT00013286 |
Completed |
A Prospective Study of Endothelial Dysfunction and Diabetic Foot Ulcer Risk |
|
- Device: Prevention Diabetic Foot Ulcer
|
Observational
|
|
- US Department of Veterans Affairs
- VA Office of Research and Development
|
U.S. Fed |
- Time Perspective: Prospective
|
|
750 |
All |
18 Years and older (Adult, Older Adult) |
NCT00013286 |
A2016R |
|
October 1999 |
|
September 2002 |
March 16, 2001 |
January 21, 2009 |
|
- VAMC, Seattle, WA
Seattle, Washington, United States
|
|
| 129 |
NCT02844660 |
Active, not recruiting |
Dehydrated Human Umbilical Cord Allograft in the Management of Diabetic Foot Ulcers |
|
- Biological: EpiCord
- Other: Standard of Care
|
Interventional
|
Not Applicable |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Complete Ulcer Closure
- Study Safety Measurement
- Time to complete closure
- (and 5 more...)
|
130 |
All |
18 Years and older (Adult, Older Adult) |
NCT02844660 |
ECDFU001 |
|
July 2016 |
October 2017 |
December 2017 |
July 26, 2016 |
October 26, 2017 |
|
- Central Research Associates
Birmingham, Alabama, United States - Arizona Regional Medical Research (ARMR)
Tucson, Arizona, United States - ILD Research
Carlsbad, California, United States - (and 10 more...)
|
|
| 130 |
NCT02367690 |
Withdrawn |
Study of Safety, Tolerability, and Pharmacokinetics of Topical Selinexor (KPT-330) Diabetic Foot Ulcer (DFU) Patients |
|
- Drug: Selinexor
- Other: Standard-of-Care
- Other: Vehicle Gel
|
Interventional
|
Phase 1
Phase 2 |
- Karyopharm Therapeutics Inc
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Presence of Local Skin Reactions (LSR)
- Ulcer Closure
|
0 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT02367690 |
KCP-330-501 |
|
January 2015 |
May 2015 |
September 2015 |
February 20, 2015 |
March 24, 2016 |
|
- South Pacific Clinical Trials
Auckland, New Zealand
|
|
| 131 |
NCT02972528 |
Recruiting |
The Use of Allogenic Platelet Rich Plasma for the Treatment of Diabetic Foot Ulcer |
|
- Biological: Platelet Lysate
- Biological: Platelet Poor Plasma
|
Interventional
|
Phase 1
Phase 2 |
- Hanan Jafar
- University of Jordan
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Care Provider)
- Primary Purpose: Treatment
|
- Incidence of Treatment-Emergent Adverse Events [Safety and Tolerability]) as a result of the injection
- Assess the efficacy of allogenic Platelet Lysate injection by clinical examination
|
30 |
All |
18 Years to 70 Years (Adult, Older Adult) |
NCT02972528 |
DFUUJCTC |
|
February 3, 2018 |
June 2019 |
September 2019 |
November 23, 2016 |
June 6, 2018 |
|
- Cell Therapy Center
Amman, Jordan
|
|
| 132 |
NCT02036528 |
Terminated |
Safety and Efficacy of Gentamicin Topical Gel (AppliGel-G) for Treatment of Mild to Moderately Infected Diabetic Foot Ulcers |
|
- Drug: Gentamicin Topical Gel
- Drug: Ciprofloxacin
- Drug: Doxycycline
|
Interventional
|
Phase 1
Phase 2 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Complete wound clearing of infection
- Incidence of infection cleared
- DFU Volume % Change
- DFU Area % Change
|
9 |
All |
18 Years and older (Adult, Older Adult) |
NCT02036528 |
CP-RBM-2011-001 DFU |
|
January 2014 |
December 2014 |
|
January 15, 2014 |
May 14, 2015 |
|
- Georgetown University Hospital Center
Washington, District of Columbia, United States - GF Professional Research, Corp.
Miami Lakes, Florida, United States - Florida Medical Center & Research, Inc.
Miami, Florida, United States - (and 4 more...)
|
|
| 133 |
NCT02581488 |
Completed
Has Results |
Use of Santyl in Diabetic Foot Ulcers |
- Diabetic Foot
- Foot Ulcer, Diabetic
|
- Biological: Santyl
- Other: Product containing silver
|
Interventional
|
Phase 4 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Mean Percent Change in Ulcer Area From Baseline to the End of the Treatment.
- Target Ulcer Infection Rates in Each Treatment Group During the Treatment Period as Determined by Investigator-reported Adverse Events
|
102 |
All |
18 Years and older (Adult, Older Adult) |
NCT02581488 |
017-101-09-035 |
|
October 2015 |
January 12, 2017 |
January 12, 2017 |
October 21, 2015 |
August 1, 2018 |
August 1, 2018 |
- Sylmar, California, United States
- Melbourne, Florida, United States
- Baltimore, Maryland, United States
- (and 10 more...)
|
|
| 134 |
NCT02790931 |
Recruiting |
Effects of Foot Muscle Strengthening in Daily Activity in Diabetic Neuropathic Patients |
|
- Other: Intervention Group
|
Interventional
|
Not Applicable |
- University of Sao Paulo General Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- daily physical activity
- Self selected gait speed
- Fast gait speed
- (and 11 more...)
|
77 |
All |
18 Years to 75 Years (Adult, Older Adult) |
NCT02790931 |
LaBiMPH |
|
August 2016 |
December 2019 |
December 2020 |
June 6, 2016 |
August 30, 2017 |
|
- Universidade de São Paulo
São Paulo, Brazil
|
|
| 135 |
NCT00512538 |
Terminated |
Apligraf Versus Standard Therapy in the Treatment of Diabetic Foot Ulcers |
|
- Device: Bi-layered cell therapy (Apligraf)
|
Interventional
|
Phase 3 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Time to complete wound healing (full epithelialization with no drainage)
- Incidence of complete healing
|
82 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT00512538 |
CGS0769 B304 |
|
October 2000 |
|
September 2002 |
August 7, 2007 |
August 7, 2007 |
|
|
|
| 136 |
NCT01972061 |
Enrolling by invitation |
Foot/Hand Neuromodulation for Overactive Bladder (OAB) |
|
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Voiding frequency per day
- Urine volume per void
|
80 |
All |
18 Years and older (Adult, Older Adult) |
NCT01972061 |
PRO13020474 |
FootStim |
March 2014 |
December 2018 |
December 2019 |
October 30, 2013 |
January 11, 2018 |
|
- University of Pittsburgh
Pittsburgh, Pennsylvania, United States
|
|
| 137 |
NCT01898923 |
Recruiting |
Evaluate the Efficacy and Safety of WH-1 Ointment for the Treatment of Chronic Diabetic Foot Ulcers |
|
- Drug: WH-1 ointment
- Other: Aquacel® Hydrofiber® dressing
|
Interventional
|
Phase 3 |
- Oneness Biotech Co., Ltd.
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- The incidence of complete ulcer closure
- The time of healing rate
- change in ulcer area
- (and 2 more...)
|
236 |
All |
20 Years to 80 Years (Adult, Older Adult) |
NCT01898923 |
ON101CLCT02 |
WH-1 |
September 2012 |
June 2019 |
March 2020 |
July 15, 2013 |
January 24, 2018 |
|
- Clinical Research Division
Taipei, Taiwan
|
|
| 138 |
NCT01340807 |
Completed |
A Comparison of External Mechanical Work Between Different Prosthetic Feet |
- Traumatic Amputation of Lower Extremity
|
- Other: Specialized Functional Prosthetic Training
|
Interventional
|
Not Applicable |
- Miami VA Healthcare System
|
U.S. Fed |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Symmetry in External Work
- Self Report and Performance Based Assessment Instruments
|
15 |
All |
40 Years to 65 Years (Adult, Older Adult) |
NCT01340807 |
8497.01
01 |
SEW |
March 2008 |
January 2010 |
January 2011 |
April 25, 2011 |
April 25, 2011 |
|
- Miami VAHS
Miami, Florida, United States
|
|
| 139 |
NCT02870816 |
Recruiting |
Prospective, Comparitive, Randomized Study of Allograft Versus Skin Substitute in Non-healing Diabetic Foot Ulcers |
|
- Procedure: Tissue Engineered Skin Substitute
- Device: Offloading
- Procedure: Amnionic Membrane Graft
|
Interventional
|
Not Applicable |
- Professional Education and Research Institute
- Musculoskeletal Transplant Foundation
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- The number of participants out of 60 with complete healing of their diabetic foot ulcers as measured by complete epithialization of the foot wound comparing the two active treatment groups
- Proportion of wounds healed
- Time to healing/complete closure
- Cost effectiveness of each treatment modality.
|
60 |
All |
18 Years and older (Adult, Older Adult) |
NCT02870816 |
MTF-DFU-COMP-01 |
|
August 2016 |
May 2018 |
May 2018 |
August 17, 2016 |
January 3, 2018 |
|
- Martinsville Research Institute
Martinsville, Virginia, United States - Shenandoah Lower Extremity Research Institute
Roanoke, Virginia, United States - Professional Education and Research Institute
Roanoke, Virginia, United States
|
|
| 140 |
NCT02224742 |
Completed |
LeucoPatch in the Management of Hard-to-heal Diabetic Foot Ulcers |
|
- Device: LeucoPatch
- Other: Usual care
|
Interventional
|
Phase 4 |
- Nottingham University Hospitals NHS Trust
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
|
269 |
All |
18 Years and older (Adult, Older Adult) |
NCT02224742 |
12EN005
ISRCTN27665670 |
|
August 2013 |
October 2017 |
May 2018 |
August 25, 2014 |
June 25, 2018 |
|
- Steno Diabetes Center
Gentofte, Denmark - Herlev Hospital
Herlev, Denmark - Nordsjællands Hospital
Hillerød, Denmark - (and 29 more...)
|
|
| 141 |
NCT03239457 |
Completed |
Efficacy and Safety of Heberprot-P® in Patients With Advanced Diabetic Foot Ulcer in Dasman Diabetes Institute. |
|
|
Observational
|
|
- Dasman Diabetes Institute
- Cuban Center for Genetic Engineering and Biotechnology
|
Other |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- Proportion of patients with 100% of the lesion area covered by granulation tissue.
- Time in which the formation of the granulation tissue 100%
- Need of major amputation
- Adverse events
|
50 |
All |
22 Years and older (Adult, Older Adult) |
NCT03239457 |
RA 2014-051 |
|
December 2015 |
February 2016 |
February 2016 |
August 4, 2017 |
August 4, 2017 |
|
|
|
| 142 |
NCT02666131 |
Recruiting |
A Study of Granexin Gel to Treat Diabetic Foot Ulcer |
|
- Drug: Granexin gel
- Drug: Vehicle gel
|
Interventional
|
Phase 3 |
- FirstString Research, Inc.
- INC Research
- Medical University of South Carolina
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Incidence of complete wound closure at Week 12 based on investigator assessment
- Time in days to first complete wound closure of the target ulcer based on investigator assessment over the 12 week treatment period
|
368 |
All |
18 Years and older (Adult, Older Adult) |
NCT02666131 |
2015-DFU-302 |
|
July 2015 |
June 2019 |
December 2019 |
January 28, 2016 |
February 7, 2018 |
|
- Aiyan Diabetes Center
Augusta, Georgia, United States - Spartanburg Regional Health System
Spartanburg, South Carolina, United States
|
|
| 143 |
NCT03077256 |
Recruiting |
Burst Biologics Foot and Ankle Registry |
- Foot and Ankle Disorders
- Ankle Fusion, Osteotomy
|
- Device: BioBurst Fluid, Burst Allograft
|
Observational
|
|
- Burst Biologics
- Smart-Surgical Inc. dba Burst Biologics
|
Industry |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Fusion (%) Number of fusion patients fused/all fusion patients operated
- Bone Consolidation (%) Number of osteotomy patients with bone consolidation/all osteotomy patients operated
- Visual Analog Scale (VAS)
- (and 3 more...)
|
300 |
All |
18 Years and older (Adult, Older Adult) |
NCT03077256 |
FA002 |
|
March 24, 2017 |
July 1, 2018 |
October 1, 2018 |
March 10, 2017 |
April 17, 2018 |
|
- Georgetown University Medical Center
Washington, District of Columbia, United States - Rocky Mountain Foot and Ankle
Caldwell, Idaho, United States
|
|
| 144 |
NCT01626781 |
No longer available |
A Randomized, Open-label Phase III Trial of Mapisal® Versus an Urea Hand-foot Cream as Prophylaxis for Capecitabine-induced Hand-foot Syndrome in Patients With Gastrointestinal Tumors or Breast Cancer |
- the Treatment Hand-foot Syndrome Patients With Gastrointestinal Tumors or Breast Cancer, Who Are Treated With Capecitabine
|
- Device: Mapisal
- Other: Urea hand-foot cream
|
Expanded Access
|
|
|
Other |
|
|
|
All |
18 Years and older (Adult, Older Adult) |
NCT01626781 |
AIO-LQ-0111 |
PROCAPP |
|
|
|
June 25, 2012 |
October 22, 2013 |
|
- Universitätsmedizin Mannheim, III. Medizinische Klinik
Mannheim, Germany
|
|
| 145 |
NCT03209466 |
Recruiting |
Chlorhexidine Gluconate Solution at 0.125% vs Placebo for the Healing of Grade IIB Ulcers of Diabetic Foot |
|
- Drug: Chlorhexidine gluconate at 0.125%
- Drug: Placebo Comparator with physiological saline sterile solution
|
Interventional
|
Phase 4 |
- Universidad de Guanajuato
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
|
35 |
All |
18 Years and older (Adult, Older Adult) |
NCT03209466 |
CHXDF |
|
May 11, 2017 |
December 15, 2018 |
December 30, 2018 |
July 6, 2017 |
February 5, 2018 |
|
- Universidad de Guanajuato
Leon, Guanajuato, Mexico
|
|
| 146 |
NCT01408277 |
Completed
Has Results |
Using Santyl on Diabetic Foot Ulcers |
- Diabetic Foot Ulcers
- Diabetic Foot Wounds
|
- Biological: Santyl
- Procedure: Control
|
Interventional
|
Phase 4 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Mean Percent Change in Wound Area
|
55 |
All |
18 Years and older (Adult, Older Adult) |
NCT01408277 |
017-101-09-030 |
|
August 2011 |
November 2012 |
March 2013 |
August 3, 2011 |
July 24, 2014 |
May 5, 2014 |
- Associated Foot and Ankle Specialists
Phoenix, Arizona, United States - Aung Foothealth Clinics
Tucson, Arizona, United States - Foot Healthcare Associates, PC
Southfield, Michigan, United States - (and 4 more...)
|
|
| 147 |
NCT02667327 |
Recruiting |
A Study of Granexin Gel in the Treatment of Diabetic Foot Ulcer |
|
- Drug: Granexin gel
- Other: Vehicle gel
|
Interventional
|
Phase 3 |
- FirstString Research, Inc.
- INC Research
- Medical University of South Carolina
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Incidence of complete wound closure at Week 12 based on investigator assessment
- Time in days to first complete wound closure of the target ulcer based on investigator assessment over the 12 week treatment period
|
552 |
All |
18 Years and older (Adult, Older Adult) |
NCT02667327 |
2015-DFU-301 |
|
July 2015 |
June 2019 |
December 2019 |
January 28, 2016 |
February 7, 2018 |
|
- Aiyan Diabetes Center
Augusta, Georgia, United States - Spartanburg Regional Health System
Spartanburg, South Carolina, United States
|
|
| 148 |
NCT02070835 |
Unknown † |
Study of ReCell® Treating for Diabetic Foot Ulcers |
|
- Device: ReCell®
- Procedure: skin graft
|
Interventional
|
Not Applicable |
- Hu Zhicheng
- First Affiliated Hospital, Sun Yat-Sen University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- healing rate
- recurrent rate
|
80 |
All |
18 Years to 85 Years (Adult, Older Adult) |
NCT02070835 |
SYSU-2013-048 |
|
March 2013 |
June 2016 |
June 2016 |
February 25, 2014 |
August 11, 2015 |
|
- Department of Burn Surgery, The First Affiliated Hospital of Sun Yat-sen University
Guangzhou, Guangdong, China
|
|
| 149 |
NCT01490879 |
Completed |
A Study to Investigate the Safety and Clinical Effect of Nexagon® as a Topical Treatment for Subjects With a Diabetic Foot Ulcer (DUNE) |
|
- Drug: Nexagon® Low Dose
- Drug: Nexagon® Medium Dose
- Drug: Nexagon® High Dose
- Drug: Nexagon® vehicle
|
Interventional
|
Phase 2 |
- OcuNexus Therapeutics, Inc.
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Incidence of Reference Diabetic Foot Ulcer (RDFU) complete closure determined by Investigator Assessment
- Percentage change in RDFU surface area
- Time to RDFU complete closure
- (and 3 more...)
|
168 |
All |
18 Years and older (Adult, Older Adult) |
NCT01490879 |
NEX-ULC-011 |
DUNE |
July 2012 |
February 2014 |
April 2014 |
December 13, 2011 |
May 1, 2014 |
|
- Associated Foot and Ankle Specialists, LLC
Phoenix, Arizona, United States - University of Arizona Medical Center
Tucson, Arizona, United States - Center For Clinical Research Inc.
Castro Valley, California, United States - (and 22 more...)
|
|
| 150 |
NCT01797081 |
Completed
Has Results |
BOTOX® in the Treatment of Crow's Feet Lines in Japan |
- Lateral Canthus Rhytides
- Crow's Feet Lines
|
- Biological: botulinum toxin Type A (24 U)
- Biological: botulinum toxin Type A (12 U)
- Other: Normal Saline
|
Interventional
|
Phase 3 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Percentage of Participants Achieving None or Mild on the Investigator's Assessment of the Severity of Crow's Feet Lines (CFL) at Maximum Smile Using the Facial Wrinkle Scale-Asian (FWS-A)
- Percentage of Participants Achieving a ≥1-Grade Improvement From Baseline on the Investigator's Assessment of the Severity of CFL at Rest Using the FWS-A
- Percentage of Participants Much Improved or Very Much Improved in the Subject's Assessment of Appearance of CFL as Measured by the Global Assessment of Change in Crow's Feet Lines
- Percentage of Participants Who Rate Themselves in a Younger Self-Perception of Age Category Than at Baseline
|
300 |
All |
20 Years to 64 Years (Adult) |
NCT01797081 |
191622-114 |
|
January 2013 |
July 2013 |
July 2014 |
February 22, 2013 |
February 10, 2015 |
February 10, 2015 |
|
|
| 151 |
NCT02111291 |
Completed |
Santyl Applications to Diabetic Foot Ulcers |
- Diabetic Foot Ulcers
- Diabetic Foot Wounds
|
- Biological: Collagenase SANTYL® Ointment
- Biological: Hydrogel (if needed) and foam dressing
|
Interventional
|
Phase 4 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Time to Well-established Granulation Tissue
- Adverse Event
|
215 |
All |
18 Years and older (Adult, Older Adult) |
NCT02111291 |
017-101-09-034 |
|
April 2014 |
December 2015 |
December 2015 |
April 11, 2014 |
February 17, 2016 |
|
- Mesa, Arizona, United States
- Carlsbad, California, United States
- Castro Valley, California, United States
- (and 22 more...)
|
|
| 152 |
NCT02599805 |
Unknown † |
Can Topical Oxygen Therapy (Natrox™) Improve Wound Healing in Diabetic Foot Ulcers? |
|
- Device: Natrox™ Oxygen Delivery System (ODS)
|
Interventional
|
Phase 3 |
- St. Michael's Hospital, Toronto
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Comparative change in ulcer surface area
|
20 |
All |
18 Years and older (Adult, Older Adult) |
NCT02599805 |
tba |
|
December 2015 |
December 2016 |
December 2016 |
November 9, 2015 |
November 9, 2015 |
|
|
|
| 153 |
NCT02741401 |
Unknown † |
COMplementary Hand-foot Massage to Improve Experience of illneSs Trial |
|
- Other: Usual post-operative care
- Other: Hand-foot massage
|
Interventional
|
Not Applicable |
- Zuyderland Medisch Centrum
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Change from baseline in quality of life as assessed by EuroQol-5D-L3 (EQ-5D-L3) questionnaire
- Change from baseline in anxiety and depression as assessed by Hospital Anxiety and Depression Scale (HADS) questionnaire
- Patient satisfaction about the received hospital care and hand-foot massage (if applicable) as assessed by questionnaire
- Patients' opinion and need about hand-foot massage's utility as assessed by questionnaire
|
102 |
All |
18 Years and older (Adult, Older Adult) |
NCT02741401 |
COMMIS |
COMMIS |
March 2016 |
September 2016 |
December 2016 |
April 18, 2016 |
April 22, 2016 |
|
|
|
| 154 |
NCT01581112 |
Completed |
Microbial Community Transplantation on the Armpit/Foot |
- Heavy, Bad Body Odour From Armpit
- Heavy, Bad Body Odour From Foot
|
- Biological: Microbial transplant
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change in odour severity after bacterial transplantation
- Change in molecular characterisation of the bacterial community.
- Change in molecular characterisation of the bacterial community
|
4 |
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT01581112 |
2012/256 |
|
September 2012 |
May 2013 |
June 2013 |
April 19, 2012 |
September 18, 2013 |
|
- Ghent University
Ghent, Belgium
|
|
| 155 |
NCT00134550 |
Completed |
Improving Diabetic Foot Ulcers With Atorvastatin |
|
- Drug: Atorvastatin (10 mg or 80 mg)
|
Interventional
|
Phase 2 |
- Asker & Baerum Hospital
- Pfizer
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- To assess the efficacy of atorvastatin in patients with foot ulcers and type 1 or type 2 diabetes mellitus receiving conventional foot ulcer treatment in improving foot ulcer treatment with regards to completely healed DFU, recurrence of DFU or novel DFU
- Time to complete healing (during 26 weeks of study)
- Recurrence rate of foot ulcers (during 26 weeks of study)
- (and 2 more...)
|
13 |
All |
30 Years and older (Adult, Older Adult) |
NCT00134550 |
The IDUS trial |
|
February 2005 |
March 2007 |
March 2007 |
August 25, 2005 |
September 23, 2009 |
|
- Asker and Baerum Hospital
RUD, Norway - Østfold County Hospital
Sarpsborg, Norway
|
|
| 156 |
NCT01681160 |
Completed |
Study of Maggot Therapy in Diabetic Foot Ulcers |
|
- Other: procedure:maggot therapy
- Other: conventional therapy
|
Interventional
|
Not Applicable |
- Kerman Medical University
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- change from baseline in BATES-JENSEN WOUND ASSESSMENT score at 3days and change from baseline in BATES-JENSEN WOUND ASSESSMENT score at 6 days
|
128 |
All |
40 Years to 90 Years (Adult, Older Adult) |
NCT01681160 |
86/116 |
MDT |
January 2009 |
December 2009 |
June 2011 |
September 7, 2012 |
September 10, 2012 |
|
|
|
| 157 |
NCT01221194 |
Unknown † |
Therapeutic Stockings to Prevent Foot Ulcers |
|
- Behavioral: Standard therapy
- Device: PFC Stockings
|
Interventional
|
Not Applicable |
- University of Texas Southwestern Medical Center
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Prevention
|
- The main clinical outcome is ulceration of the foot to evaluate the effectiveness of a stocking as a prevention tool
|
400 |
All |
18 Years and older (Adult, Older Adult) |
NCT01221194 |
UTSW - 7R01DK070046-04 |
|
October 2010 |
October 2012 |
October 2012 |
October 14, 2010 |
October 14, 2010 |
|
- Parkland Health & Hospital Systems
Dallas, Texas, United States - UT Southwestern Medical Center at Dallas
Dallas, Texas, United States - Scott & White
Temple, Texas, United States - University of Manchester
Manchester, United Kingdom
|
|
| 158 |
NCT02818322 |
Recruiting |
The Role of Telemedical Monitoring in Diabetic Foot Ulcer Care |
- Diabetic Foot - Telemedical Monitoring
|
- Device: telemedical monitoring ( T)
- Device: classic monitoring
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
|
|
150 |
All |
18 Years and older (Adult, Older Adult) |
NCT02818322 |
PA15083 |
A15-06 |
April 2016 |
October 2018 |
October 2018 |
June 29, 2016 |
June 29, 2016 |
|
- Chu de Reims
Reims, France
|
|
| 159 |
NCT02841969 |
Recruiting |
Management of the Diabetic Foot Using Electrolysed Water |
|
- Other: Electrolysed water
- Other: Prontosan
|
Interventional
|
Not Applicable |
- NHS Lanarkshire
- Aqualution Systems Ltd
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: Double (Participant, Care Provider)
- Primary Purpose: Treatment
|
- Rate of complete wound healing
|
200 |
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT02841969 |
NEWfeet_01
L16077 |
NEWfeet |
February 28, 2017 |
June 30, 2018 |
September 30, 2018 |
July 22, 2016 |
September 14, 2017 |
|
- Hairmyres Hospital
East Kilbride, Lanarkshire, United Kingdom
|
|
| 160 |
NCT01912092 |
Completed |
Askina Calgitrol Paste Diabetic Foot Ulcers |
- Diabetic Foot Ulcer (DFU)
|
- Device: Askina Calgitrol paste
|
Interventional
|
Not Applicable |
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Clinical signs of local infection (Presence of erythema, pain, tenderness, warmth or induration)
- Adverse events or Adverse device related event
- Evaluation of wound bed (necrosis, slough, granulation, epithelialisation)
- (and 2 more...)
|
22 |
All |
18 Years and older (Adult, Older Adult) |
NCT01912092 |
OPM-O-H-1205 |
|
April 2013 |
July 2014 |
July 2014 |
July 30, 2013 |
July 31, 2015 |
|
- Diabetic Foot and metabolic diseases clinic
Milan, Italy - IRCCS Casa di Cura MultiMedica
Mila, Italy
|
|
| 161 |
NCT03370874 |
Recruiting |
Clinical Study to Evaluate Efficacy and Safety of ALLO-ASC-DFU in Patients With Diabetic Foot Ulcers. |
|
- Biological: ALLO-ASC-DFU
- Procedure: Vehicle sheet
|
Interventional
|
Phase 3 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Proportions of subjects who achieved complete wound closure
- Time taken to complete wound closure between the two groups
- Proportions of subjects who achieved complete wound closure by the classification of Wagner Grade between the two groups
- (and 2 more...)
|
164 |
All |
18 Years to 75 Years (Adult, Older Adult) |
NCT03370874 |
ALLO-ASC-DFU-301 |
|
July 4, 2018 |
June 30, 2019 |
September 30, 2019 |
December 13, 2017 |
August 3, 2018 |
|
- Korea University Kuro Hospital
Seoul, Korea, Republic of
|
|
| 162 |
NCT01217463 |
Completed
Has Results |
The TRAfermin in Neuropathic Diabetic Foot Ulcer Study - Southern Europe The TRANS-South Study |
- Diabetic Foot Ulcer of Neuropathic Origin
|
- Drug: Trafermin 0.01% spray
|
Interventional
|
Phase 3 |
- Olympus Biotech Corporation
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Wound Closure Rate of Diabetic Foot Ulcers (DFUs) of Neuropathic Topical Daily Application of Trafermin 0.01% Spray Compared With Placebo, in Addition
- Relative Wound Area Regression of 40% or More at 6 Week
|
201 |
All |
18 Years and older (Adult, Older Adult) |
NCT01217463 |
TFM-CL3-001
2010-021014-33 |
TRANS-South |
November 2010 |
March 2012 |
February 2013 |
October 8, 2010 |
August 5, 2014 |
August 5, 2014 |
- Ostrava- Vitkovice, Czech Republic
- Prague, Czech Republic
- Prague, Czech Republic
- (and 21 more...)
|
|
| 163 |
NCT01097850 |
Withdrawn |
Topical Henna Preparation for the Treatment of Hand Foot Skin Syndrome |
|
|
Interventional
|
Phase 2 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- • To compare the severity of HFS in subjects receiving topical natural henna paste treatment along with using CeraVe™ moisturizing cream concurrently on the treatment side and using only CeraVe™ moisturizing cream on the control side.
- To examine quality of life, comparing natural henna treatment versus CeraVe™ alone, using the Skindex-16 questionnaire
|
0 |
All |
18 Years and older (Adult, Older Adult) |
NCT01097850 |
NU 09D1 |
|
March 2010 |
January 2012 |
January 2012 |
April 2, 2010 |
December 12, 2014 |
|
|
|
| 164 |
NCT01217476 |
Completed
Has Results |
The TRAfermin in Neuropathic Diabetic Foot Ulcer Study - Northern Europe The TRANS-North Study |
- Diabetic Foot Ulcer of Neuropathic Origin
|
- Drug: Trafermin 0.01% spray
|
Interventional
|
Phase 3 |
- Olympus Biotech Corporation
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Wound Closure Rate of Diabetic Foot Ulcers (DFUs) of Neuropathic Origin After a Maximum of 12 Weeks Topical Daily Application of Trafermin 0.01% Spray Compared With Placebo, in Addition to Best Local Cares
- Relative Wound Area Regression of 40% or More at 6 Week
|
207 |
All |
18 Years and older (Adult, Older Adult) |
NCT01217476 |
TFM-CL3-002
2010-021015-16 |
TRANS-North |
December 2010 |
May 2012 |
March 2013 |
October 8, 2010 |
August 5, 2014 |
August 5, 2014 |
- Brussels, Belgium
- Liege, Belgium
- Rumst, Belgium
- (and 34 more...)
|
|
| 165 |
NCT01940250 |
Completed |
Magnesium Sulphate for Severe Hand, Foot and Mouth Disease in Vietnam |
- Hand, Foot and Mouth Disease
|
- Drug: Magnesium Sulphate
- Drug: Sterile water
|
Interventional
|
Phase 2 |
- Oxford University Clinical Research Unit, Vietnam
- Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
- Children's Hospital Number 1, Ho Chi Minh City, Vietnam
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Number of patients who experience at least one of the clinical events listed below (composite endpoint)
- Death
- Blood pressure criteria necessitating addition of milrinone following Vietnam Ministry of Health guidelines for the treatment of hand, foot and mouth disease
- (and 7 more...)
|
26 |
All |
6 Months to 15 Years (Child) |
NCT01940250 |
02EI |
|
April 21, 2014 |
June 30, 2016 |
December 28, 2016 |
September 12, 2013 |
March 7, 2017 |
|
- Children's Hospital 1
Ho Chi Minh City, Vietnam - Hospital for Tropical Diseases
Ho CHi Minh City, Vietnam
|
|
| 166 |
NCT03372304 |
Recruiting |
Catheter-based Peripheral Regional Anesthesia After Orthopedic Surgery to the Foot or Ankle |
|
|
Interventional
|
Phase 4 |
- Nordsjaellands Hospital
- Innovation Fund Denmark
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Postoperative pain, 1-72 hours postoperatively
- Opioid consumption, 1-72 hours postoperatively
- Volume of patient-initiated boluses, 1-72 hours postoperatively
|
90 |
All |
18 Years to 99 Years (Adult, Older Adult) |
NCT03372304 |
H-17021730 |
API-FOOT |
November 29, 2017 |
August 1, 2018 |
December 31, 2018 |
December 13, 2017 |
December 15, 2017 |
|
- Department of Anesthesiology, Nordsjællands Hospital Hillerød
Hillerød, Denmark
|
|
| 167 |
NCT03341559 |
Recruiting |
Spatial Frequency Domain Imaging (SFD) for Assessment of Diabetic Foot Ulcer Development and Healing |
|
- Other: Spatial Frequency Domain Imaging (SFDI)
|
Observational
|
|
- University of Southern California
- Modulated Imaging Inc.
|
Other / Industry |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Perfusion in lower extremities
|
30 |
All |
18 Years and older (Adult, Older Adult) |
NCT03341559 |
APP-17-06886 |
|
March 20, 2018 |
March 20, 2019 |
May 1, 2020 |
November 14, 2017 |
May 3, 2018 |
|
- Keck Medical Center of USC
Los Angeles, California, United States
|
|
| 168 |
NCT01531517 |
Terminated |
Study of the Efficacy of PedyPhar® Ointment on the Diabetic Foot Ulcers |
|
- Drug: Royal Jelly and Panthenol (PedyPhar® Ointment)
- Drug: Panthenol Ointment
|
Interventional
|
Phase 3 |
- European Egyptian Pharmaceutical Industries
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Healing of the Ulcer
- reduction of infection in the ulcer site
- local reaction that may be due to study drug
|
47 |
All |
18 Years to 70 Years (Adult, Older Adult) |
NCT01531517 |
Pedyphar2012 |
PED111 |
July 2011 |
July 2012 |
July 2013 |
February 13, 2012 |
February 20, 2015 |
|
- Alexandria University Hospitals
Alexandria, Egypt - Cairo University Hospitals
Alexandria, Egypt
|
|
| 169 |
NCT03248466 |
Recruiting |
PRG Combined With Autologous BMMSCs for Treatment of Diabetic Foot Ulcer |
|
- Biological: PRG combined with BMMSCs transplantation
|
Interventional
|
Early Phase 1 |
- Third Military Medical University
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Amputation rate
- hospital stay
- Wound healing time
- Transcutaneous oxygen partial pressure
|
60 |
All |
20 Years to 70 Years (Adult, Older Adult) |
NCT03248466 |
endocrine department of TMMU |
|
August 30, 2017 |
January 1, 2020 |
July 1, 2020 |
August 14, 2017 |
August 14, 2017 |
|
- Southwest Hospital of the Third Military Medical University
Chongqing, Chongqing, China - Endocrine Department, the First Affiliated Hospital of the Third Military Medical University
Chongqing, Chongqing, China
|
|
| 170 |
NCT01643967 |
Unknown † |
Clinical Trial to Evaluate the Efficacy and Safety of the Use of Ozone Versus Sunflower Oil in Treating Diabetic Foot |
|
- Other: sunflower oil
- Other: Ozone Therapy
|
Interventional
|
Phase 3 |
- Philozon Geradores de Ozonio LTDA
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Evaluate the efficacy and safety of ozone released by the device Philozon Medplus in the treatment of patients with diabetic foot.
- Evaluate the release of ozone in the environment by equipment MEdplus after insufflation rectal in patients with diabetic foot.
|
100 |
All |
18 Years and older (Adult, Older Adult) |
NCT01643967 |
PHI-OZO-01-10 |
PHIOZO0110 |
June 2012 |
December 2012 |
January 2013 |
July 18, 2012 |
July 18, 2012 |
|
- Associação Hospitalar Beneficente São Vicente de Paulo
Passo Fundo, Rio Grande do Sul, Brazil
|
|
| 171 |
NCT00286598 |
Completed |
Feet First: Promoting Physical Activity Among People With Diabetes Mellitus and Insensate Feet |
- Diabetes Mellitus
- Peripheral Neuropathies
|
|
Interventional
|
Phase 1 |
- University of Missouri-Columbia
- Robert Wood Johnson Foundation
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change in weight-bearing physical activity (steps/day)
- Partial or greater depth foot ulcer (Wagner Gr. 1 or deeper)
- Falls
- (and 2 more...)
|
79 |
All |
50 Years and older (Adult, Older Adult) |
NCT00286598 |
UMHS IRB 1040047 |
|
January 2005 |
June 2007 |
June 2008 |
February 3, 2006 |
October 5, 2016 |
|
- University of Missouri
Columbia, Missouri, United States
|
|
| 172 |
NCT02831075 |
Recruiting |
A Clinical Study Using Adipose-derived Stem Cells for Diabetic Foot |
- Peripheral Vascular Disease
- Ischemia
- Diabetic Foot
|
- Biological: Adipose-derived stem cell
- Biological: saline
|
Interventional
|
Phase 1 |
- Jie Shen
- Nanfang Hospital of Southern Medical University
- Academy Military Medical Science, China
- (and 3 more...)
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Area of diabetic foot ulcers
- Improvement of transcutaneous oxygen partial pressure (TcPO2)
- Improvement of microvascular cutaneous reactivity by laser Doppler perfusion monitoring (LDPM)
- (and 2 more...)
|
240 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT02831075 |
Southern Medical University |
|
January 2015 |
December 2017 |
December 2018 |
July 13, 2016 |
April 7, 2017 |
|
- the Third Affiliated Hospital of Southern Medical University
Guangzhou, Guangdong, China
|
|
| 173 |
NCT02789033 |
Completed |
Efficacy of the Combination of Isosorbide Dinitrate Spray and Chitosan in Diabetic Foot Ulcers |
|
- Drug: Chitosan
- Drug: Isosorbide dinitrate
- Drug: Placebo
|
Interventional
|
Phase 3 |
- University of Guadalajara
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
|
60 |
All |
Child, Adult, Older Adult |
NCT02789033 |
030-2010 |
|
June 2015 |
August 2015 |
August 2015 |
June 2, 2016 |
June 2, 2016 |
|
|
|
| 174 |
NCT01087957 |
Completed
Has Results |
WalkAide Compared to Ankle-Foot Orthosis (AFO) in Stroke Patients |
|
- Device: WalkAide
- Other: Ankle-Foot Orthosis (AFO)
|
Interventional
|
Not Applicable |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Gait Velocity
- Stroke Impact Scale (SIS) Composite Score
- Device Related Serious Adverse Events
- (and 8 more...)
|
495 |
All |
18 Years and older (Adult, Older Adult) |
NCT01087957 |
INSTRIDE |
|
March 2010 |
February 2012 |
June 2013 |
March 16, 2010 |
May 13, 2014 |
May 13, 2014 |
- The Loma Linda University Medical Center
Loma Linda, California, United States - The Los Angeles VA
Los Angeles, California, United States - Casa Colina Centers for Rehabilitation
Pomona, California, United States - (and 26 more...)
|
|
| 175 |
NCT02994966 |
Recruiting |
Diabetes Foot Care Clinical Pathway - Orpyx Medical Technologies |
|
- Device: Surrosense
- Other: Standard care
|
Interventional
|
Not Applicable |
- University of Alberta
- Alberta Innovates Health Solutions
- Orpyx Medical Technologies Inc.
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Foot ulcer recurrence
- Time to re-ulceration
- Patient satisfaction
- (and 5 more...)
|
120 |
All |
18 Years and older (Adult, Older Adult) |
NCT02994966 |
AICE-201500873 |
DFCCP-Orpyx |
November 2016 |
September 2018 |
December 2019 |
December 16, 2016 |
May 2, 2018 |
|
- Brooks Home Care
Brooks, Alberta, Canada - Peter Lougheed Centre
Calgary, Alberta, Canada - Slave Lake Family Care Clinic
Slave Lake, Alberta, Canada
|
|
| 176 |
NCT02536651 |
Completed |
Reliability and Validity of the Finnish Visual Analogue Scale Foot and Ankle and the Lower Extremity Functional Scale |
- Foot Diseases
- Ankle Disease
|
|
Observational
|
|
- Helsinki University Central Hospital
- Central Finland Hospital District
|
Other |
- Observational Model: Cohort
- Time Perspective: Cross-Sectional
|
- The validity of the Visual Analogue Scale Foot and Ankle and the Lower Extremity Functional Scale
- The reliability of the Visual Analogue Scale Foot and Ankle and the Lower Extremity Functional Scale
- Visual Analogue Scale Foot and Ankle questionnaire
- (and 4 more...)
|
120 |
All |
18 Years and older (Adult, Older Adult) |
NCT02536651 |
343/13/03/02/13/5 |
|
September 2014 |
August 2015 |
August 2015 |
September 1, 2015 |
August 16, 2017 |
|
|
|
| 177 |
NCT01070433 |
Completed |
A Clinical Study of the Safety and Efficacy of MEBO Wound Ointment in Subjects With Diabetic Foot Ulcers |
|
- Drug: MEBO Wound Ointment (MEBO)
- Other: Standard of Care
|
Interventional
|
Phase 2 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- The incidence of complete healing of the target ulcer.
- Time required to achieve complete healing (days).
- Absolute and percentage change in ulcer surface area from baseline to endpoint.
|
75 |
All |
18 Years and older (Adult, Older Adult) |
NCT01070433 |
MEBO-DFU-PII-001 v. 4.0 |
|
September 2012 |
September 2013 |
December 2013 |
February 18, 2010 |
April 18, 2018 |
|
- HOPE Research Institute
Phoenix, Arizona, United States - Center for Clinical Research, Inc.
Castro Valley, California, United States - ILD Consulting, Inc.
Encinitas, California, United States - (and 6 more...)
|
|
| 178 |
NCT00387101 |
Terminated |
Efficacy and Safety Study in the Treatment of Chronic Diabetic Foot Ulcers |
|
- Device: Dermal - Living Skin Replacement (Dermal - LSR)
|
Interventional
|
Phase 3 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- To determine the efficacy and safety of Dermal-LSR plus Standard of Care (SOC) for the treatment of chronic diabetic foot ulcers in comparison to treatment with SOC alone.
|
288 |
All |
18 Years to 84 Years (Adult, Older Adult) |
NCT00387101 |
RS03-2004 |
|
February 2006 |
September 2007 |
April 2008 |
October 12, 2006 |
May 2, 2008 |
|
- Southern Arizona Veterans Administration Health Care System, 3601 S. 6th Avenue (2-112)
Tuscon, Arizona, United States - Veterans Affairs Northern Health Care System, Sacramento VA Medical Center at Mather
Mather, California, United States - San Diego Research Center 4452 Park Boulevard Suite 210, San Diego
San Diego, California, United States - (and 9 more...)
|
|
| 179 |
NCT02202668 |
Terminated |
Transcutaneous Raman Spectroscope (TRS) Analyses of Diabetic Foot Ulcers |
|
|
Interventional
|
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Device Feasibility
|
- Transcutaneous Raman spectra of subcutaneous deep wound soft tissue and underlying bone
- Wound temperature post-Transcutaneous Raman Spectroscope
|
5 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT02202668 |
HUM00083401 |
|
September 2014 |
November 2014 |
November 2014 |
July 29, 2014 |
April 19, 2017 |
|
- University of Michigan
Ann Arbor, Michigan, United States
|
|
| 180 |
NCT02563522 |
Recruiting |
Safety and Efficacy Study of VM202 in the Treatment of Chronic Non-Healing Foot Ulcers |
|
- Genetic: VM202
- Drug: Placebo
|
Interventional
|
Phase 3 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Treatment
|
- Confirmed target wound closure by the 4 month follow-up
- Time to complete wound closure of foot ulcer
- Time to the amputations
- (and 3 more...)
|
300 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT02563522 |
VMNHU-003 |
|
January 2017 |
June 2019 |
December 2019 |
September 30, 2015 |
July 20, 2018 |
|
- Central Research Associates, Inc.
Birmingham, Alabama, United States - University of Arizona
Tucson, Arizona, United States - NEA Baptist
Jonesboro, Arkansas, United States - (and 20 more...)
|
|
| 181 |
NCT03307499 |
Recruiting |
NeoPatch Used as Adjunct in Foot and Ankle Tendon Surgery |
- Tendinopathy
- Tendon Tear
- Tendon Injuries
- Foot Ankle Injuries
|
|
Interventional
|
Not Applicable |
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Quantitative ultrasound assessment of post-operative adhesions
- Change in quantitative ultrasound assessment of post-operative adhesions
- Qualitative ultrasound assessment of post-operative adhesions
- (and 8 more...)
|
10 |
All |
18 Years and older (Adult, Older Adult) |
NCT03307499 |
HPM1701.000-M |
|
September 21, 2017 |
March 2019 |
March 2019 |
October 11, 2017 |
October 11, 2017 |
|
- Advanced Foot and Ankle Surgeons
Sycamore, Illinois, United States
|
|
| 182 |
NCT03414216 |
Not yet recruiting |
Surgical Offloading Procedures for Diabetic Foot Ulcers |
|
- Procedure: Group 1 early offloading surgery
- Procedure: Group 2 - off-loading in fiberglass cast
|
Interventional
|
Not Applicable |
- Assaf Harofeh MC
- Assaf-Harofeh Medical Center
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Failure to cure
- Any recurrence of any ulcer at same location
|
100 |
All |
18 Years to 120 Years (Adult, Older Adult) |
NCT03414216 |
0094-17-ASF |
|
March 1, 2018 |
December 31, 2019 |
December 31, 2019 |
January 29, 2018 |
January 29, 2018 |
|
|
|
| 183 |
NCT02995863 |
Completed |
This Research Hypothesizes That the Use of a Rigid Rocker Sole Reduces the Recurrence Rate of Diabetic Foot Ulcers in Patients With Peripheral Neuropathy. |
- Diabetic Foot
- Diabetic Foot Ulcer
|
- Device: Rigid Rocker Sole Footwear
- Device: Therapeutic Footwear
|
Interventional
|
Not Applicable |
- Universidad Complutense de Madrid
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Presence of diabetic foot ulcer
- Ankle Joint movility
- Mobility of the First metatarsal Joint
- (and 8 more...)
|
73 |
All |
18 Years and older (Adult, Older Adult) |
NCT02995863 |
UComplutenseMadrid |
|
December 10, 2016 |
December 10, 2017 |
May 10, 2018 |
December 19, 2016 |
May 16, 2018 |
|
- Clínica Universitaria de Podología de la Universidad Complutense de Madrid
Madrid, Spain
|
|
| 184 |
NCT01013792 |
Terminated
Has Results |
A Comparison of an Investigational Dressing to Tegaderm Matrix Wound Dressing in the Management of Diabetic Foot Ulcers |
|
|
Interventional
|
Not Applicable |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Treatment
|
- Percent Diabetic Foot Ulcer Area Reduction From Baseline to Last Treatment Visit
|
30 |
All |
18 Years and older (Adult, Older Adult) |
NCT01013792 |
05-011091 |
|
November 2009 |
July 2012 |
July 2012 |
November 16, 2009 |
March 23, 2015 |
March 23, 2015 |
- Terry Treadwell, MD
Montgomery, Alabama, United States - Alex Reyzelman, DPM
Castro Valley, California, United States - Wyatt Payne, MD
Bay Pines, Florida, United States - (and 3 more...)
|
|
| 185 |
NCT02123628 |
Completed |
Antibiotic Treatment Duration for Non-Surgically-Treated Diabetic Foot Osteomyelitis |
|
- Drug: duration of the antibiotic therapy
|
Interventional
|
Phase 4 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Primary outcome measure was the proportion of patients of each group with remission of diabetic foot osteomyelitis at the end of follow-up.
- tolerance to treatment in each group of patients
|
40 |
All |
18 Years and older (Adult, Older Adult) |
NCT02123628 |
2006-00625-14 |
C H R O N O S |
June 2007 |
June 2010 |
September 2012 |
April 25, 2014 |
April 25, 2014 |
|
- Dron Hospital
Tourcoing, Nord, France
|
|
| 186 |
NCT00685698 |
Completed
Has Results |
Safety and Efficacy Study of TG-873870 (Nemonoxacin) in Diabetic Foot Infections |
|
- Drug: TG-873870 (Nemonoxacin)
|
Interventional
|
Phase 2 |
- TaiGen Biotechnology Co., Ltd.
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Clinical Success (in ITT Population)
- Microbiological Success Rate
- Clinical Success (in PP Population)
- (and 14 more...)
|
40 |
All |
18 Years and older (Adult, Older Adult) |
NCT00685698 |
TG-873870-04 |
|
June 2008 |
April 2009 |
June 2009 |
May 28, 2008 |
January 9, 2015 |
January 9, 2015 |
- HealthCare Partners
Montebello, California, United States - HealthCare Partners
Pasadena, California, United States - The Amputation Prevention Center at Broadlawns Medical Center
Des Moines, Iowa, United States - (and 13 more...)
|
|
| 187 |
NCT03276312 |
Completed |
Autologous Micro-fragmented Adipose Tissue in the Treatment of Minor Amputations of Diabetic Foot |
|
|
Interventional
|
Not Applicable |
- University of Modena and Reggio Emilia
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Healing time
- Safety: All types of adverse events will be collected
- Incidence of relapse
- (and 4 more...)
|
112 |
All |
18 Years and older (Adult, Older Adult) |
NCT03276312 |
ADF01 |
|
April 2015 |
March 2018 |
March 2018 |
September 8, 2017 |
June 8, 2018 |
|
- University of Modena and Reggio Emilia
Modena, Italy
|
|
| 188 |
NCT01594762 |
Completed
Has Results |
Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers |
|
- Drug: Topical pexiganan cream 0.8%
- Drug: Topical placebo cream
- Other: Standard wound care
|
Interventional
|
Phase 3 |
- Dipexium Pharmaceuticals, Inc.
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Treatment
|
- Number of Participants With Clinical Response
- Number of Participants With Microbiological Response
- Number of Participants With Treatment-Emergent Adverse Events (TEAE)
|
200 |
All |
18 Years and older (Adult, Older Adult) |
NCT01594762 |
DPX-306 |
OneStep-2 |
June 2014 |
July 2016 |
July 2016 |
May 9, 2012 |
June 14, 2017 |
June 14, 2017 |
- Phoenix, Arizona, United States
- Tucson, Arizona, United States
- Jonesboro, Arkansas, United States
- (and 36 more...)
|
|
| 189 |
NCT01590758 |
Completed
Has Results |
Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers |
|
- Drug: Topical pexiganan cream 0.8%
- Drug: Topical placebo cream
- Other: Standard wound care
|
Interventional
|
Phase 3 |
- Dipexium Pharmaceuticals, Inc.
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Treatment
|
- Number of Participants With Clinical Response
- Number of Participants With Microbiological Success
- Number of Participants With Treatment-emergent Adverse Events (TEAE)
|
189 |
All |
18 Years and older (Adult, Older Adult) |
NCT01590758 |
DPX-305 |
OneStep-1 |
June 2014 |
August 2016 |
August 2016 |
May 3, 2012 |
June 14, 2017 |
June 14, 2017 |
- Birmingham, Alabama, United States
- Glendale, Arizona, United States
- Mesa, Arizona, United States
- (and 27 more...)
|
|
| 190 |
NCT01833468 |
Completed |
Functional Limitations Due To The Foot Involvement In Spondyloarthritis |
- Ankylosing Spondylitis
- Psoriatic Arthritis
|
|
Observational
|
|
- Vakif Gureba Training and Research Hospital
|
Other |
- Observational Model: Case-Crossover
- Time Perspective: Cross-Sectional
|
- The foot-related functional status of SpA patients
|
30 |
All |
18 Years to 70 Years (Adult, Older Adult) |
NCT01833468 |
Foot-SpA |
|
February 2013 |
April 2013 |
April 2013 |
April 16, 2013 |
April 17, 2013 |
|
|
|
| 191 |
NCT00968292 |
Unknown † |
Stability and 3D Motion Study of an Experimental Prosthetic Foot |
|
- Device: Experimental prosthetics foot (K3 Promoter)
|
Interventional
|
Phase 3 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Four Square Step Test
- Amputee Mobility Predictor
- Timed Up and Go Test
- (and 3 more...)
|
50 |
All |
18 Years to 90 Years (Adult, Older Adult) |
NCT00968292 |
Rifkin-2 |
|
May 2010 |
August 2010 |
August 2010 |
August 28, 2009 |
August 28, 2009 |
|
- Center for Gait and Movement Analysis
Arvada, Colorado, United States
|
|
| 192 |
NCT03205436 |
Recruiting |
Affinity Prospective Diabetic Foot Trial Crossover Group |
|
- Other: Affinity human amniotic membrane
|
Interventional
|
Not Applicable |
- SerenaGroup, Inc.
- NuTech Medical, Inc
|
Other / Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Time to initial closure of diabetic foot ulcer
- Proportion of healed wounds
- Mean wastage of graft
- Mean cost to heal
|
20 |
All |
18 Years and older (Adult, Older Adult) |
NCT03205436 |
NT-DFU-AFF-02 |
|
May 1, 2017 |
June 2019 |
August 2019 |
July 2, 2017 |
April 23, 2018 |
|
- GF Professional Research
Miami Lakes, Florida, United States - Barry University Clinical Research
North Miami Beach, Florida, United States - The Foot and Ankle Wellness Center
Ford City, Pennsylvania, United States - (and 3 more...)
|
|
| 193 |
NCT02936115 |
Terminated |
TruSkin®: Study for the Treatment of Chronic Diabetic Foot Ulcers |
|
- Other: TruSkin®
- Other: Wound Cover
|
Interventional
|
Phase 4 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Proportion of Patients that achieve a 50% or greater reduction in wound size by 8 weeks
- Proportion of patients that achieve complete closure of the index wound by 12 weeks
- Proportion of Patients that achieve a 50% or greater reduction in wound size by 4 weeks
- (and 4 more...)
|
14 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT02936115 |
Osiris Protocol 351 |
|
July 2016 |
April 2017 |
April 2017 |
October 18, 2016 |
April 6, 2017 |
|
- Florida, Florida, United States
- Illinois, Illinois, United States
- Michigan, Michigan, United States
- (and 2 more...)
|
|
| 194 |
NCT00947726 |
Completed |
Ceramide Containing Multivesicular Emulsion Application . . . |
- Foot Transepidermal Water Loss in Patients in NIDDM
- Foot Dryness in Patients With NIDDM
|
|
Interventional
|
Not Applicable |
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
|
NIH |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Decrease transepidermal water loss and foot dryness in study subjects.
|
30 |
All |
18 Years and older (Adult, Older Adult) |
NCT00947726 |
DK7676 (completed) |
|
July 2009 |
October 2009 |
|
July 28, 2009 |
April 20, 2011 |
|
|
|
| 195 |
NCT02882893 |
Unknown † |
Efficacy and Safety of DWP450 for the Treatment of Crows Feet Lines |
|
- Drug: Clostridium Botulinum A Toxin
|
Interventional
|
Phase 2
Phase 3 |
- Daewoong Pharmaceutical Co. LTD.
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Facial Wrinkle Scale(FWS) severity of Crow's feet lines(CFL) at maximum smile as assessed by investigators
|
238 |
All |
18 Years to 75 Years (Adult, Older Adult) |
NCT02882893 |
DW_DWP450005 |
|
August 2016 |
January 2017 |
April 2017 |
August 30, 2016 |
August 30, 2016 |
|
- Konkuk University Medical Center
Seoul, Korea, Republic of
|
|
| 196 |
NCT02074683 |
Completed |
Fat Grafting for Pedal Fat Pad Atrophy in Diabetics |
- Pedal Pad Atrophy
- Diabetes Mellitus
|
- Procedure: Year A Pathway
- Procedure: Year B Pathway
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Durability of Relief and reduction of foot pressure
- Measurement of pedal pressure and plantar tissue thickness
- Measurement of durability of fat grafting vs silicone or other fillers
- Assessment of pain and skin lesions
|
10 |
All |
18 Years and older (Adult, Older Adult) |
NCT02074683 |
PRO13080186 |
|
November 2013 |
April 2018 |
April 2018 |
February 28, 2014 |
April 4, 2018 |
|
- University of Pittsburgh Department of Plastic Medicine
Pittsburgh, Pennsylvania, United States
|
|
| 197 |
NCT01154374 |
Completed |
A Clinical Study of the Safety and Efficacy of MEBO® Wound Ointment in Subjects With Diabetic Foot Ulcers (Pilot) |
|
- Drug: MEBO Wound Ointment
- Procedure: Standard of Care (sterile saline moistened gauze)
|
Interventional
|
Phase 2 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- The incidence of complete healing of the target ulcer.
- Time required to achieve complete healing (days).
- Absolute and percentage change in ulcer surface area from baseline to endpoint.
|
7 |
All |
18 Years to 79 Years (Adult, Older Adult) |
NCT01154374 |
MEBO-DFU-PILOTII-001 |
|
November 2010 |
October 2011 |
October 2011 |
June 30, 2010 |
April 18, 2018 |
|
- Blume Podiatry Group, P.C.
New Haven, Connecticut, United States - Boston University School of Medicine
Boston, Massachusetts, United States
|
|
| 198 |
NCT02066714 |
Completed |
Neurodevelopment Outcomes Following Severe Hand Foot and Mouth Disease in Vietnam |
- Hand Foot and Mouth Disease
|
|
Observational
|
|
- Oxford University Clinical Research Unit, Vietnam
- Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
- Children's Hospital Number 1, Ho Chi Minh City, Vietnam
- Preventative Medical Centre, District 8, Ho Chi Minh City, Vietnam
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Cognitive, language and motor development
- Neurological status
|
243 |
All |
up to 4 Years (Child) |
NCT02066714 |
08RS |
08RS |
June 2013 |
December 2014 |
August 2016 |
February 19, 2014 |
October 4, 2016 |
|
- Hospital of Tropical Diseases
Ho Chi Minh City, Vietnam
|
|
| 199 |
NCT02260609 |
Completed |
GrafixCORE®: Open-Label Study to Evaluate the Safety and Efficacy of GrafixCORE® for Complex Diabetic Foot Wounds |
- Complex Diabetic Foot Wounds
|
|
Interventional
|
Phase 4 |
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- 100% granulation of wound as determined by the investigator
- Time to 100% granulation
- Number of applications of Grafix®
- (and 2 more...)
|
31 |
All |
18 Years to 85 Years (Adult, Older Adult) |
NCT02260609 |
Osiris Protocol 310 |
|
October 2014 |
October 2015 |
|
October 9, 2014 |
February 2, 2016 |
|
- Carl T. Hayden Medical Research Foundation
Phoenix, Arizona, United States - Southern Arizona VA Health Care System
Tucson, Arizona, United States - Miami VA
Miami, Florida, United States - South Shore Hospital
Weymouth, Massachusetts, United States
|
|
| 200 |
NCT02354066 |
Completed |
The Effect of Foot Orthoses on the Braking Response Time |
|
- Device: Hallux valgus Shoe
- Device: Forefoot relief shoe
- Device: Retail Shoe
|
Interventional
|
Not Applicable |
- Medical University Innsbruck
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
|
- Brake response time after hallux valgus surgery with the investigated foot orthoses
|
42 |
All |
18 Years and older (Adult, Older Adult) |
NCT02354066 |
602006052013
INS-621000-0500 |
|
June 2013 |
August 2015 |
September 2015 |
February 3, 2015 |
September 23, 2015 |
|
- Department of Orthopedic; Medical University of Innsbruck
Innsbruck, Tyrol, Austria
|
|
Create an RSS feed from your search for:
Download the search results for: