293 studies found for:    diabetes and type 1 and open and active | Open Studies
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1 Recruiting A Study Comparing the Efficacy and Safety of the Morning Injection of Toujeo Versus Lantus in Patients With Type 1 Diabetes Mellitus
Condition: Type 1 Diabetes Mellitus
Interventions: Drug: Insulin glargine (U300) HOE901;   Drug: Insulin glargine HOE901;   Drug: Insulin glulisine HMR1964;   Drug: Insulin aspart;   Drug: Insulin lispro
2 Not yet recruiting Evaluation of the Dreamed Advice4U Pro for Automated Insulin Pump Setting Adjustments in Children and Adolescents With Type 1 Diabetes- The Advice4U Pro Study
Condition: Type1 Diabetes Mellitus
Interventions: Device: DreaMed Advice4U Pro;   Other: Medical guided recommendation
3 Recruiting Evaluation of Automated Insulin Pump Settings Using the MD-Logic Advise4U
Condition: Type 1 Diabetes
Interventions: Device: MD-Logic Pump Advisor;   Other: Control Group
4 Not yet recruiting Closed Loop From Onset in Type 1 Diabetes
Conditions: Diabetes Mellitus;   Type 1 Diabetes
Interventions: Device: FlorenceM;   Other: Multiple Daily Injections
5 Recruiting Brown Adipose Tissue in Type 1 Diabetes
Condition: Type1diabetes
Intervention: Radiation: Positron emission tomography with tracer 18F-deoxy glucose
6 Not yet recruiting Closed-loop Control of Glucose Levels (Artificial Pancreas) for 5 Days in Adults With Type 1 Diabetes
Condition: Type 1 Diabetes
Interventions: Other: 5-day intervention with single-hormone closed-loop strategy;   Other: 5-day intervention with sensor-augmented pump therapy;   Other: 5-day intervention with dual-hormone closed-loop strategy;   Device: Insulin pump;   Device: Continuous glucose monitoring system;   Drug: Insulin;   Drug: Glucagon
7 Not yet recruiting Day and Night Closed-loop in Young People With Type 1 Diabetes
Conditions: Diabetes Mellitus;   Diabetes Mellitus, Type 1;   Glucose Metabolism Disorders;   Endocrine System Diseases;   Autoimmune Diseases
Interventions: Device: FlorenceM;   Device: Insulin pump therapy
8 Recruiting An Exploratory Study on the Effects of Repeat Doses of Albiglutide Compared to Exenatide on Gastric Myoelectrical Activity and Gastric Emptying in Type 2 Diabetes Mellitus Subjects
Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Exenatide;   Drug: Albiglutide
9 Not yet recruiting Closed-loop Control of Glucose Levels (Artificial Pancreas) for 2 Weeks in Adults With Type 1 Diabetes
Condition: Type 1 Diabetes
Interventions: Other: 2-week intervention with sensor-augmented pump therapy;   Other: 2-week intervention with single-hormone closed-loop strategy;   Other: 2-week intervention with dual-hormone closed-loop strategy;   Device: Insulin pump;   Device: Continuous glucose monitoring system;   Drug: Insulin;   Drug: Glucagon
10 Recruiting A 24-week Open-Label, Phase 3b Trial With a 28-week Extension to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin Compared to Insulin Glargine in Subjects withType 2 Diabetes Who Have Glycemic Control on Metformin
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: Saxagliptin, Onglyza;   Drug: Dapagliflozin, Farxiga;   Drug: Glargine insulin;   Drug: Metformin XR
11 Not yet recruiting Closed-loop Control of Glucose Levels (Artificial Pancreas) for 2 Weeks in Adolescents and Adults With Type 1 Diabetes
Condition: Type 1 Diabetes
Interventions: Other: 15-week intervention with sensor-augmented pump;   Other: 15-week intervention with single-hormone closed-loop;   Other: 15-week intervention with dual-hormone closed-loop;   Device: Insulin pump;   Device: Continuous glucose monitoring system;   Drug: Insulin;   Drug: Glucagon
12 Recruiting Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (FRC) Versus GLP-1 Receptor Agonist in Patients With Type 2 Diabetes, With a FRC Extension Period
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: insulin glargine/lixisenatide fixed ratio combination;   Drug: liraglutide;   Drug: exenatide;   Drug: exenatide extended-release;   Drug: albiglutide;   Drug: dulaglutide;   Drug: metformin;   Drug: pioglitazone
13 Recruiting Physical Activity and Glycemic Control in Adolescents
Condition: Type 1 Diabetes
Interventions: Behavioral: Reinforcement for meeting targeted physical activity goals;   Other: Standard of Care
14 Recruiting Comparison of the Safety and Efficacy of HOE901-U300 With Lantus in Children and Adolescents With Type 1 Diabetes Mellitus
Condition: Type 1 Diabetes Mellitus
Interventions: Drug: insulin glargine (U300);   Drug: insulin glargine;   Drug: fast-acting insulin analogue
15 Not yet recruiting A Study of the Effect of Glucagon-like Peptide 1(GLP-1) Receptor Agonist in Combination With Metformin Therapy on Diabetes Remission in Subjects With Newly Diagnosed Type 2 Diabetes Who Are Overweight or Obese
Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Exenatide;   Drug: BIAsp30;   Drug: Metformin
16 Recruiting Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (LixiLan) to Lixisenatide on Top of Oral Anti-diabetic Drugs (OADs) With Type 2 Diabetes in Japan
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: Insulin glargine/Lixisenatide (HOE901/AVE0010);   Drug: Lixisenatide (AVE0010);   Drug: Oral anti-diabetic drugs
17 Recruiting Cross-sectional, Case Control Study of Neurocognitive Performance During Hyperglycemia , and Brain Tissue Integrity in Youth With Type 1 Diabetes and in Healthy
Condition: Diabetes Mellitus, Type 1
Interventions: Device: MRI including DTI , EEG, CGMS;   Behavioral: Neurocognitive tests
18 Not yet recruiting Study of MiniMed™ 640G Insulin Pump With SmartGuard™ in Prevention of Low Glucose Events in Adults With Type 1 Diabetes
Condition: Type 1 Diabetes
Interventions: Device: MiniMed™640G and Suspend before low;   Device: MiniMed™640G
19 Not yet recruiting Safety and Efficacy of Artificial Pancreas With and Without a Meal Detection Module on Glycemic Control in Adolescents With Type 1 Diabetes After a Missed Bolus
Condition: Diabetes Mellitus, Type 1
Interventions: Other: Missed Bolus Intervention;   Device: Insulin infusion pump;   Other: Meals;   Drug: Human insulin
20 Recruiting Closed-loop Control of Postprandial Glucose Levels After Meals With Different Macronutrients Content in Adults With Type 1 Diabetes
Condition: Type 1 Diabetes
Interventions: Device: Patient's insulin pump;   Drug: Insulin;   Device: Dexcom G4 Platinum glucose sensor;   Other: Single-hormone closed-loop

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Study has passed its completion date and status has not been verified in more than two years.