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83 studies found for:    congenital heart defects OR congenital heart disease OR valve defects | Open Studies | NIH, U.S. Fed
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Rank Status Study
21 Recruiting A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and Pharmacokinetics
Conditions: Transposition of the Great Arteries;   Tetralogy of Fallot;   Ventricular Septal Defect
Intervention: Drug: Dexmedetomidine
22 Recruiting Fontan Udenafil Exercise Longitudinal Assessment Trial
Condition: Single Ventricle Heart Disease
Interventions: Drug: Udenafil;   Drug: Placebo
23 Recruiting MRI Assessment of Arrythmia Ablation Lesions
Conditions: Ventricular Tachycardia;   Cardiac Arrhythmia
Intervention: Other: MRI scan
24 Recruiting Study on Moebius Syndrome and Other Congenital Facial Weakness Disorders
Conditions: Brain Disorders;   Birth Defects;   Craniofacial Differences
Intervention:
25 Recruiting Clinical and Basic Investigations Into Known and Suspected Congenital Disorders of Glycosylation
Condition: Congenital Disorders of Glycosylation
Intervention:
26 Recruiting Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias
Conditions: Congenital Hemolytic Anemia;   Diamond-Blackfan Anemia
Interventions: Procedure: Radiotherapy;   Drug: Alemtuzumab (Campath );   Drug: Sirolimus (Rapamune )
27 Recruiting Mutations in Genes Associated With Pentalogy of Cantrell
Conditions: Inborn Genetic Diseases;   Pentalogy of Cantrell
Intervention:
28 Recruiting Natural History of Noncirrhotic Portal Hypertension
Conditions: Cystic Fibrosis;   Immunologic Deficiency Syndrome;   Turner Syndrome;   Congenital Hepatic Fibrosis;   Idiopathic Non-Cirrhotic Portal Hypertension
Intervention:
29 Recruiting Antioxidant Therapy in RYR1-Related Congenital Myopathy
Condition: Neuromuscular Disease
Intervention: Drug: N-acetylcysteine
30 Recruiting Radiation-Free Heart Catheterization Using MRI
Conditions: Aortic Coarctation;   Cardiomyopathy;   Atrial Septal Defect;   Aortic Stenosis;   Post Heart Transplant Catheter Procedure;   Patent Ductus Arteriosus
Interventions: Procedure: MRI guided cardiac catheterization;   Device: Magnetic resonance imaging
31 Recruiting Study of Alkaptonuria
Condition: Alkaptonuria
Intervention:
32 Recruiting Thymus Transplantation Safety-Efficacy
Conditions: Complete DiGeorge Anomaly;   DiGeorge Syndrome;   DiGeorge Anomaly;   Complete DiGeorge Syndrome
Interventions: Biological: Thymus Tissue for Transplantation;   Procedure: Blood Draw;   Drug: Rabbit anti-thymocyte globulin;   Drug: Cyclosporine;   Drug: Tacrolimus;   Drug: Methylprednisolone or Prednisolone;   Drug: Basiliximab;   Drug: Mycophenolate mofetil
33 Recruiting Molecular Determinants of Coronaruy Artery Disease
Conditions: Coronary Artery Disease;   Arteriovenous Malformations;   Myocardial Infarction
Intervention:
34 Recruiting Exercise in Genetic Cardiovascular Conditions
Conditions: Hypertrophic Cardiomyopathy;   Long QT Syndrome
Intervention:
35 Recruiting Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease
Condition: Kartagener Syndrome
Intervention:
36 Recruiting The Clinical Study of Sex Chromosome Variants
Conditions: Klinefelter Syndrome;   Male Factor Infertility;   Female Factor Infertility;   Turner Syndrome;   47, XYY;   47, XXX;   47, XXY;   45, X
Intervention:
37 Recruiting CiPA Phase 1 ECG Biomarker Validation Study
Conditions: Drug-induced QT Prolongation;   Pharmacokinetics;   Pharmacodynamics
Interventions: Drug: Ranolazine;   Drug: Verapamil;   Drug: Lopinavir / Ritonavir;   Drug: Chloroquine;   Drug: Placebo;   Drug: Dofetilide and Diltiazem
38 Recruiting Screening for Subjects to Participate in Studies of Blood Disorders
Conditions: Bone Marrow Transplant;   Sickle Cell Disease;   G-CSF
Intervention:
39 Recruiting Risk of Diabetes in Young Turner Syndrome Patients
Condition: Turner Syndrome
Intervention:
40 Recruiting Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease
Condition: Sickle Cell Disease
Interventions: Procedure: haploidentical stem cell transplant;   Drug: sirolimus;   Drug: campath;   Drug: pentostatin;   Drug: cyclophosphamide

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Study has passed its completion date and status has not been verified in more than two years.