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77 studies found for:    congenital heart defects OR congenital heart disease OR valve defects | Open Studies | NIH, U.S. Fed
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Rank Status Study
21 Recruiting MRI Assessment of Arrythmia Ablation Lesions
Conditions: Ventricular Tachycardia;   Cardiac Arrhythmia
Intervention: Other: MRI scan
22 Unknown  Immunologic Evaluation in Patients With DiGeorge Syndrome or Velocardiofacial Syndrome
Conditions: DiGeorge Syndrome;   Shprintzen Syndrome;   Chromosome Abnormalities;   Abnormalities, Multiple;   Conotruncal Cardiac Defects
Intervention:
23 Recruiting Thymus Transplantation Safety-Efficacy
Conditions: Complete DiGeorge Anomaly;   DiGeorge Syndrome;   DiGeorge Anomaly;   Complete DiGeorge Syndrome
Interventions: Biological: Thymus Tissue for Transplantation;   Procedure: Blood Draw;   Drug: Rabbit anti-thymocyte globulin;   Drug: Cyclosporine;   Drug: Tacrolimus;   Drug: Methylprednisolone or Prednisolone;   Drug: Basiliximab;   Drug: Mycophenolate mofetil
24 Recruiting Exercise in Genetic Cardiovascular Conditions
Conditions: Hypertrophic Cardiomyopathy;   Long QT Syndrome
Intervention:
25 Recruiting Study on Moebius Syndrome and Other Congenital Facial Weakness Disorders
Conditions: Brain Disorders;   Birth Defects;   Craniofacial Differences
Intervention:
26 Recruiting The Clinical Study of Sex Chromosome Variants
Conditions: Klinefelter Syndrome;   Male Factor Infertility;   Female Factor Infertility;   Turner Syndrome;   47, XYY;   47, XXX;   47, XXY;   45, X
Intervention:
27 Recruiting Genetics of Primary Ciliary Dyskinesia
Conditions: Primary Ciliary Dyskinesia;   Kartagener Syndrome
Intervention:
28 Recruiting Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease
Condition: Kartagener Syndrome
Intervention:
29 Unknown  Clinical Proteomic Research for the Brain
Conditions: Ischemic Brain Injury;   Stroke;   Healthy Individual;   Patent Foramen Ovale (PFO);   Neurovascular Injury
Intervention:
30 Unknown  Race Difference Moxifloxacin-induced QT Prolongation Between Healthy Chinese and Caucasian Volunteers
Condition: Cardiac Toxicity
Intervention: Drug: Moxifloxacin
31 Recruiting Risk of Diabetes in Young Turner Syndrome Patients
Condition: Turner Syndrome
Intervention:
32 Recruiting Genetics of QT Prolongation With Antiarrhythmics
Conditions: Long QT Syndrome;   Drug Toxicity
Intervention: Drug: Dofetilide and/or sotalol
33 Recruiting A Registry to Determine the Clinical and Genetic Risk Factors for Torsade De Pointes
Conditions: Long qt Syndrome;   Torsade de Pointes
Intervention:
34 Recruiting Study of Alkaptonuria
Condition: Alkaptonuria
Intervention:
35 Recruiting Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias
Conditions: Congenital Hemolytic Anemia;   Diamond-Blackfan Anemia
Interventions: Procedure: Radiotherapy;   Drug: Alemtuzumab (Campath );   Drug: Sirolimus (Rapamune )
36 Recruiting Evaluating the Genetic Causes and Progression of Cholestatic Liver Diseases (LOGIC)
Conditions: Liver Diseases;   Alagille Syndrome;   Alpha 1-Antitrypsin Deficiency
Intervention:
37 Recruiting Clinical and Basic Investigations Into Known and Suspected Congenital Disorders of Glycosylation
Condition: Congenital Disorders of Glycosylation
Intervention:
38 Recruiting Mutations in Genes Associated With Pentalogy of Cantrell or Non-Muscle Myosin II Syndromes
Conditions: Inborn Genetic Diseases;   Pentalogy of Cantrell
Intervention:
39 Recruiting Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Conditions: Infection;   Hypertension;   Pain;   Reflux;   Edema;   Hyperlipidemia;   Hypotension;   Hypercholesterolemia;   Sedation;   Anxiolysis;   Benzodiazepine Withdrawal;   Bipolar Disorder;   Autistic Disorder;   Schizophrenia;   Influenza Treatment or Prophylaxis;   Acute Decompensated Heart Failure;   Stable Angina;   Life-threatening Fungal Infections;   Nosocomial Pneumonia;   Community Acquired Pneumonia;   Acute Bacterial Exacerbation of Chronic Bronchitis;   Complicated Skin and Skin Structure Infections;   Uncomplicated Skin and Skin Structure Infections;   Chronic Bacterial Prostatitis;   Complicated Urinary Tract Infections;   Acute Pyelonephritis;   Uncomplicated Urinary Tract Infections;   Inhalational Anthrax (Post-Exposure);   Infantile Hemangioma;   Withdrawal;   Inflammation;   Bacterial Septicemia;   Cytomegalovirus Retinitis;   Herpes Simplex Virus;   Adenovirus;   Brain Swelling;   Airway Swelling;   Adrenal Insufficiency;   Anxiety;   Nausea;   Vomiting;   Convulsions;   Muscle Spasms;   Seizures;   Epilepsy;   Bartonellosis;   Brucellosis;   Cholera;   Plague;   Psittacosis;   Q Fever;   Relapsing Fever;   Rocky Mountain Spotted Fever;   Trachoma;   Tularemia;   Typhus Fever;   Bronchospasm;   Cardiac Arrest;   Hypersensitivity Reaction;   Cyanide Poisoning;   Acute Bacterial Sinusitis;   Bacterial Meningitis;   Sepsis;   Gastroparesis;   Opioid Addiction;   Migraines;   Headaches
Intervention: Drug: The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
40 Recruiting WS-SAVE Study (Williams Syndrome Skin and Vessel Elasticity Study)
Conditions: Williams Syndrome;   Cardiovascular Disease;   Multisystem Developmental Disorder;   Elastin Gene Deletion;   Hypertension
Intervention:

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