Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
36 studies found for:    cholangiocarcinoma AND biliary tree | Open Studies
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Rank Status Study
1 Recruiting A Phase 2 Trial of Regorafenib as A Single Agent in Advanced and Metastatic Biliary Tract Carcinoma/Cholangiocarcinoma Patients Who Have Failed First-line Chemotherapy
Condition: Metastatic Biliary Tract Carcinoma
Intervention: Drug: Regorafenib
2 Recruiting Clinical Trial to Investigate the Efficacy of Treatment With Gemcitabine/Pazopanib in Patients With Biliary Tree Cancer
Conditions: Cholangiocarcinoma;   Gallbladder Carcinoma;   Biliary Carcinoma
Intervention: Drug: Gemcitabine-Pazopanib
3 Recruiting Radioactive Stents for Treatment of Unresectable Biliary Tract Cancer
Conditions: Intrahepatic Cholangiocarcinoma;   Cholangiocarcinoma of the Extrahepatic Bile Duct;   Ampullary Carcinoma;   Biliary Obstruction
Interventions: Device: radioactive stent;   Device: plastic stent
4 Recruiting Gemcitabine Hydrochloride and Oxaliplatin or Observation in Treating Patients With Biliary Tract Cancer That Has Been Removed by Surgery
Conditions: Extrahepatic Bile Duct Cancer;   Gallbladder Cancer;   Liver Cancer
Interventions: Drug: gemcitabine hydrochloride;   Drug: oxaliplatin;   Other: clinical observation;   Procedure: adjuvant therapy;   Procedure: quality-of-life assessment
5 Recruiting Adjuvant Chemotherapy With Gemcitabine and Cisplatin Compared to Observation After Curative Intent Resection of Biliary Tract Cancer
Conditions: Cholangiocarcinoma;   Gall Bladder Carcinoma
Interventions: Drug: Gemcitabine;   Drug: Cisplatin;   Other: Observation
6 Recruiting Active Symptom Control Alone or With mFOLFOX Chemotherapy for Locally Advanced/ Metastatic Biliary Tract Cancers
Conditions: Biliary Tract Cancer;   Gallbladder Cancer;   Cholangiocarcinoma;   Ampullary Cancer
Interventions: Other: Active Symptom Control;   Drug: L-folinic acid;   Drug: 5 FU;   Drug: Oxaliplatin
7 Not yet recruiting ABC-08: Phase Ib Trial of Acelarin in Combination With Cisplatin in Locally Advanced/ Metastatic Biliary Tract Cancers
Conditions: Biliary Tract Cancer;   Gallbladder Cancer;   Cholangiocarcinoma;   Ampullary Cancer
Interventions: Drug: Acelarin;   Drug: Cisplatin
8 Recruiting ADH-1, Gemcitabine Hydrochloride and Cisplatin in Treating Patients With Metastatic Pancreatic or Biliary Tract Cancer That Cannot Be Removed By Surgery
Conditions: Acinar Cell Adenocarcinoma of the Pancreas;   Adenocarcinoma of the Gallbladder;   Adult Primary Cholangiocellular Carcinoma;   Advanced Adult Primary Liver Cancer;   Cholangiocarcinoma of the Gallbladder;   Duct Cell Adenocarcinoma of the Pancreas;   Localized Unresectable Adult Primary Liver Cancer;   Periampullary Adenocarcinoma;   Recurrent Adult Primary Liver Cancer;   Recurrent Gallbladder Cancer;   Recurrent Pancreatic Cancer;   Stage II Gallbladder Cancer;   Stage III Pancreatic Cancer;   Stage IIIA Gallbladder Cancer;   Stage IIIB Gallbladder Cancer;   Stage IV Pancreatic Cancer;   Stage IVA Gallbladder Cancer;   Stage IVB Gallbladder Cancer
Interventions: Drug: ADH-1;   Drug: cisplatin;   Drug: gemcitabine hydrochloride;   Other: laboratory biomarker analysis
9 Recruiting Study of GEMOX(Gemcitabine/Oxaliplatin) Versus XELOX(Xeloda/Oxaliplatin) in Advanced Biliary Tract Carcinoma
Condition: Biliary Tract (Intrahepatic, Extrahepatic Cholangiocarcinoma, Gall Bladder) Cancer
Intervention: Drug: Oxaliplatin
10 Recruiting A Randomized Study of GEMOX With or Without Cetuximab in Locally Advanced and Metastatic BTC
Conditions: Cholangiocarcinoma;   Adenocarcinoma of Gallbladder
Interventions: Drug: gemcitabine, oxaliplatin;   Drug: cetuximab, gemcitabine, oxaliplatin
11 Recruiting Study of Hepatic Arterial Infusion to Treat Biliary Tract Carcinomas
Condition: Biliary Tract Cancer
Intervention: Drug: Oxaliplatin, Fluorouracil, Leucovorin, Capecitabine
12 Recruiting Storage of Bile From Routine Procedures to Study Risk Factors
Conditions: Gallbladder Cancer;   Cholangiocarcinoma;   Biliary Tract Cancer
Intervention:
13 Recruiting Study of CX-4945 in Combination With Gemcitabine and Cisplatin for Frontline Treatment of Cholangiocarcinoma
Condition: Cholangiocarcinoma
Interventions: Drug: CX-4945;   Drug: Cisplatin;   Drug: Gemcitabine
14 Recruiting Comparison of Endoscopic Radiofrequency Ablation Versus Photodynamic Therapy for Inoperable Cholangiocarcinoma
Condition: Cholangiocarcinoma
Interventions: Procedure: Self expanding metallic stent (SEMS);   Procedure: Endoscopic radiofrequency ablation (ERFA);   Procedure: Photodynamic therapy (PDT)
15 Not yet recruiting Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer
Conditions: Breast Cancer;   Colon Cancer;   Extrahepatic Bile Duct Cancer;   Gallbladder Cancer;   Gastrointestinal Cancer;   Liver and Intrahepatic Biliary Tract Cancer;   Lung Cancer;   Metastatic Cancer;   Pancreatic Cancer;   Rectal Cancer;   Thyroid Gland Medullary Carcinoma;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Procedure: radionuclide imaging;   Procedure: positron emission tomography;   Other: laboratory biomarker analysis;   Other: pharmacological study;   Drug: Cu 64 anti-CEA monoclonal antibody M5A IV
16 Unknown  PiCCA Study (Panitumumab in Combination With Cisplatin/Gemcitabine)
Condition: Cholangiocarcinomas
Interventions: Drug: Cisplatin, Gemcitabine, Panitumumab;   Drug: Cisplatin, Gemcitabine
17 Recruiting CPI-613 in Treating Patients With Advanced or Metastatic Bile Duct Cancer That Cannot Be Removed By Surgery
Conditions: Adult Primary Cholangiocellular Carcinoma;   Advanced Adult Primary Liver Cancer;   Cholangiocarcinoma of the Extrahepatic Bile Duct;   Cholangiocarcinoma of the Gallbladder;   Localized Unresectable Adult Primary Liver Cancer;   Metastatic Extrahepatic Bile Duct Cancer;   Recurrent Adult Primary Liver Cancer;   Recurrent Extrahepatic Bile Duct Cancer;   Unresectable Extrahepatic Bile Duct Cancer
Intervention: Drug: 6,8-bis(benzylthio)octanoic acid
18 Unknown  A Randomized, Open, Prospective Clinical Research of Fluorouracil Implant to Improve Surgical Gallbladder Cancer and Bile Duct Cancer
Conditions: Gallbladder Cancer;   Bile Duct Cancer
Intervention: Drug: Fluorouracil implant
19 Unknown  Comparison Between Fully Covered Metal Stents and Plastic Stents in Preoperative Biliary Drainage
Conditions: Biliary Tract Cancer;   Complications of Surgical Procedures or Medical Care;   Disorder of Bile Duct Stent
Interventions: Device: Fully covered metal stents;   Device: Plastic stents
20 Recruiting Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies
Conditions: Acinar Cell Adenocarcinoma of the Pancreas;   Adenocarcinoma of the Gallbladder;   Adenocarcinoma of Unknown Primary;   Adult Primary Cholangiocellular Carcinoma;   Advanced Adult Primary Liver Cancer;   Cholangiocarcinoma of the Extrahepatic Bile Duct;   Cholangiocarcinoma of the Gallbladder;   Diffuse Adenocarcinoma of the Stomach;   Duct Cell Adenocarcinoma of the Pancreas;   Intestinal Adenocarcinoma of the Stomach;   Localized Unresectable Adult Primary Liver Cancer;   Metastatic Carcinoma of Unknown Primary;   Metastatic Extrahepatic Bile Duct Cancer;   Mixed Adenocarcinoma of the Stomach;   Mucinous Adenocarcinoma of the Colon;   Mucinous Adenocarcinoma of the Rectum;   Newly Diagnosed Carcinoma of Unknown Primary;   Signet Ring Adenocarcinoma of the Colon;   Signet Ring Adenocarcinoma of the Rectum;   Stage III Pancreatic Cancer;   Stage IIIA Colon Cancer;   Stage IIIA Gallbladder Cancer;   Stage IIIA Gastric Cancer;   Stage IIIA Rectal Cancer;   Stage IIIB Colon Cancer;   Stage IIIB Gallbladder Cancer;   Stage IIIB Gastric Cancer;   Stage IIIB Rectal Cancer;   Stage IIIC Colon Cancer;   Stage IIIC Gastric Cancer;   Stage IIIC Rectal Cancer;   Stage IV Gastric Cancer;   Stage IV Pancreatic Cancer;   Stage IVA Colon Cancer;   Stage IVA Gallbladder Cancer;   Stage IVA Rectal Cancer;   Stage IVB Colon Cancer;   Stage IVB Gallbladder Cancer;   Stage IVB Rectal Cancer;   Unresectable Extrahepatic Bile Duct Cancer
Interventions: Drug: oxaliplatin;   Drug: irinotecan hydrochloride;   Drug: leucovorin calcium;   Drug: fluorouracil;   Other: laboratory biomarker analysis

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Indicates status has not been verified in more than two years