39 studies found for:    cholangiocarcinoma AND biliary tree | Open Studies
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Rank Status Study
1 Recruiting A Phase 2 Trial of Regorafenib as A Single Agent in Advanced and Metastatic Biliary Tract Carcinoma/Cholangiocarcinoma Patients Who Have Failed First-line Chemotherapy
Condition: Metastatic Biliary Tract Carcinoma
Intervention: Drug: Regorafenib
2 Recruiting Clinical Trial to Investigate the Efficacy of Treatment With Gemcitabine/Pazopanib in Patients With Biliary Tree Cancer
Conditions: Cholangiocarcinoma;   Gallbladder Carcinoma;   Biliary Carcinoma
Intervention: Drug: Gemcitabine-Pazopanib
3 Recruiting Radioactive Stents for Treatment of Unresectable Biliary Tract Cancer
Conditions: Intrahepatic Cholangiocarcinoma;   Cholangiocarcinoma of the Extrahepatic Bile Duct;   Ampullary Carcinoma;   Biliary Obstruction
Interventions: Device: radioactive stent;   Device: plastic stent
4 Recruiting Adjuvant Chemotherapy With Gemcitabine and Cisplatin Compared to Observation After Curative Intent Resection of Biliary Tract Cancer
Conditions: Cholangiocarcinoma;   Gall Bladder Carcinoma
Interventions: Drug: Gemcitabine;   Drug: Cisplatin;   Other: Observation
5 Recruiting A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)
Conditions: Liver Cell Caricinoma;   Liver Cancer;   Hapatocellular Carcinoma;   Liver Neoplasms
Interventions: Drug: Durvalumab;   Drug: Tremelimumab;   Procedure: TACE;   Procedure: RFA;   Procedure: Cryoablation
6 Recruiting Metabolic Syndrome, Bile Acids, Hepatocellular Carcinoma and Cholangiocarcinoma
Conditions: Morbid Obesity;   Vertical Sleeve Gastrectomy;   Metabolic Syndrome;   Hepatocellular Carcinoma;   Cholangiocarcinoma;   Disorder of Bile Acid and Cholesterol Metabolism
Intervention:
7 Recruiting Active Symptom Control Alone or With mFOLFOX Chemotherapy for Locally Advanced/ Metastatic Biliary Tract Cancers
Conditions: Biliary Tract Cancer;   Gallbladder Cancer;   Cholangiocarcinoma;   Ampullary Cancer
Interventions: Other: Active Symptom Control;   Drug: L-folinic acid;   Drug: 5 FU;   Drug: Oxaliplatin
8 Recruiting ABC-08: Phase Ib Trial of Acelarin in Combination With Cisplatin in Locally Advanced/ Metastatic Biliary Tract Cancers
Conditions: Biliary Tract Cancer;   Gallbladder Cancer;   Cholangiocarcinoma;   Ampullary Cancer
Interventions: Drug: Acelarin;   Drug: Cisplatin
9 Recruiting Study of CX-4945 in Combination With Gemcitabine and Cisplatin for Frontline Treatment of Cholangiocarcinoma
Condition: Cholangiocarcinoma
Interventions: Drug: CX-4945;   Drug: Cisplatin;   Drug: Gemcitabine
10 Recruiting Bile Usefulness for Detecting IgG4-related Sclerosing Cholangitis
Conditions: IgG4-related Sclerosing Cholangitis;   IgG4-related Disease
Intervention:
11 Recruiting ADH-1, Gemcitabine Hydrochloride and Cisplatin in Treating Patients With Metastatic Pancreatic or Biliary Tract Cancer That Cannot Be Removed By Surgery
Conditions: Acinar Cell Adenocarcinoma of the Pancreas;   Adenocarcinoma of the Gallbladder;   Adult Primary Cholangiocellular Carcinoma;   Advanced Adult Primary Liver Cancer;   Cholangiocarcinoma of the Gallbladder;   Duct Cell Adenocarcinoma of the Pancreas;   Localized Unresectable Adult Primary Liver Cancer;   Periampullary Adenocarcinoma;   Recurrent Adult Primary Liver Cancer;   Recurrent Gallbladder Cancer;   Recurrent Pancreatic Cancer;   Stage II Gallbladder Cancer;   Stage III Pancreatic Cancer;   Stage IIIA Gallbladder Cancer;   Stage IIIB Gallbladder Cancer;   Stage IV Pancreatic Cancer;   Stage IVA Gallbladder Cancer;   Stage IVB Gallbladder Cancer
Interventions: Drug: ADH-1;   Drug: cisplatin;   Drug: gemcitabine hydrochloride;   Other: laboratory biomarker analysis
12 Recruiting Liver and Biliary Tumor Tissue Registry
Conditions: Hepatocellular Carcinoma;   Cholangiocarcinoma
Intervention:
13 Recruiting Tremelimumab With Chemoembolization or Ablation for Liver Cancer
Conditions: Liver Cell Caricinoma;   Liver Cancer;   Hepatocellular Carcinoma;   Liver Neoplasms
Interventions: Drug: Tremelimumab;   Procedure: TACE;   Procedure: Radiofrequency Ablation (RFA);   Radiation: SBRT;   Procedure: Cryoablation
14 Recruiting In Vitro Models of Liver and Pancreatic Cancer
Conditions: Cholangiocarcinoma;   Hepatocellular Carcinoma;   Pancreatic Neoplasm
Intervention: Genetic: Organoid in vitro culture
15 Recruiting Copanlisib (BAY 80-6946) in Combination With Gemcitabine and Cisplatin in Advanced Cholangiocarcinoma
Conditions: Biliary Carcinoma;   Gall Bladder Carcinoma;   Cholangiocarcinoma;   Gastrointestinal Tumor
Interventions: Drug: Cisplatin;   Drug: Gemcitabine;   Drug: Copanlisib
16 Recruiting Gemcitabine, Cisplatin, and Abraxane in Advanced Biliary Cancers
Condition: Biliary Tract Cancer
Interventions: Drug: Abraxane (Nab-Paclitaxel);   Drug: Cisplatin;   Drug: Gemcitabine;   Behavioral: Phone Calls
17 Recruiting Molecularly Target Therapy With GEMOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma
Conditions: Cholangiocarcinoma of the Extrahepatic Bile Duct;   Gallbladder Cancer
Interventions: Procedure: biological test;   Drug: GEMOX;   Drug: Cetuximab;   Drug: Trastuzumab;   Drug: Gefitinib;   Drug: Lapatinib;   Drug: Everolimus;   Drug: Sorafenib;   Drug: Crizotinib
18 Recruiting Photodynamic Therapy (PDT) for Palliation of Cholangiocarcinoma
Conditions: Cholangiocarcinoma;   Biliary Stricture;   Biliary Obstruction;   Bile Duct Cancer
Intervention: Procedure: Photodynamic Therapy
19 Not yet recruiting Ricolinostat, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable or Metastatic Cholangiocarcinoma
Conditions: Non-Resectable Cholangiocarcinoma;   Recurrent Cholangiocarcinoma;   Stage III Extrahepatic Bile Duct Cancer;   Stage III Intrahepatic Cholangiocarcinoma;   Stage IIIA Hilar Cholangiocarcinoma;   Stage IIIB Hilar Cholangiocarcinoma;   Stage IVA Extrahepatic Bile Duct Cancer;   Stage IVA Hilar Cholangiocarcinoma;   Stage IVA Intrahepatic Cholangiocarcinoma;   Stage IVB Extrahepatic Bile Duct Cancer;   Stage IVB Hilar Cholangiocarcinoma;   Stage IVB Intrahepatic Cholangiocarcinoma;   Unresectable Extrahepatic Bile Duct Carcinoma
Interventions: Drug: Cisplatin;   Drug: Gemcitabine Hydrochloride;   Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study;   Drug: Ricolinostat
20 Recruiting Efficacy and Safety of Endobiliary Radiofrequency Ablation by Using a Novel RF Catheter (ELRA®) on Maintaining the Patency of Endobiliary Metal Drainage in Patients With Malignant Biliary Strictures : A Double-arm Comparable Study
Condition: Cholangiocarcinoma, Gallbladder Cancer, Pancreatic Cancer
Interventions: Device: Radiofrequency ablation with stenting;   Device: stenting

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Study has passed its completion date and status has not been verified in more than two years.