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198 studies found for:    chelation AND heart
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Rank Status Study
1 Completed
Has Results
Trial to Assess Chelation Therapy (TACT)
Condition: Coronary Artery Disease
Interventions: Drug: EDTA;   Drug: EDTA Placebo;   Dietary Supplement: High Dose Vitamin;   Dietary Supplement: High Dose Vitamin Placebo
2 Completed Intensive Combined Chelation Therapy for Iron-Induced Cardiac Disease in Patients With Thalassemia Major
Conditions: Iron Overload;   Cardiomyopathy
Interventions: Drug: Deferoxamine and Deferiprone;   Drug: Deferoxamine
3 Recruiting Amlodipine as Adjuvant Treatment to Iron Chelation for Prevention of Cardiac Iron Overload in Thalassemia Patients
Conditions: Beta-Thalassemia;   Iron Overload
Interventions: Drug: Amlodipine;   Drug: Deferasirox
4 Recruiting Trial to Assess Chelation Therapy 2
Conditions: Diabetes;   Myocardial Infarction
Interventions: Drug: disodium EDTA;   Dietary Supplement: Oral Multi Vitamins/Minerals (OMVM);   Drug: Placebo disodium EDTA;   Dietary Supplement: Placebo Oral Multi Vitamins/Minerals (OMVM)
5 Active, not recruiting Cardiac Function in Patients With Hereditary Hemochromatosis
Condition: Hemochromatosis
Intervention:
6 Recruiting Evaluation of Myocardial Iron Deposition in Patients of Heart Failure Using T2* MR Imaging
Conditions: Heart Failure;   Iron Overload;   Cardiomyopathies
Intervention: Other: MR T2* imaging
7 Completed
Has Results
An Epidemiological Study to Assess Iron Overload Using MRI in Patients With Transfusional Siderosis (TIMES Study)
Condition: Thalassemia, Non-transfusional-dependent Thalassemia (NTDT), Myeloplastic Dysplasia (MDS), Other Anemia
Intervention: Device: MRI scan
8 Completed Safety and Efficacy of Deferasirox in Combination With Desferoxamine in β-thalassaemia Patients With Severe Cardiac Iron Overload
Conditions: Transfusion-dependent β-thalassemia Patients;   Cardiac Iron Overload
Interventions: Drug: Deferasirox;   Drug: Deferasirox + Deferoxamine
9 Recruiting Reproductive Capacity and Iron Burden in Thalassemia
Condition: THALASSEMIA MAJOR
Interventions: Other: Blood Draw/Semen Exam;   Other: Retrospective data/Chart Review/Relevant Clinical Results;   Other: Pituitary MRI
10 Completed
Has Results
Evaluating Use of Deferasirox as Compared to Deferoxamine in Treating Cardiac Iron Overload
Conditions: Transfusional Iron Overload;   Transfusional Hemosiderosis
Interventions: Drug: Core Study: Deferasirox;   Drug: Core Study: Deferoxamine;   Drug: Extension: deferoxamine to deferasirox;   Drug: Extension: deferasirox to deferoxamine;   Drug: Deferasirox;   Drug: Deferoxamine
11 Active, not recruiting Effect of Spirulina Compared to Amlodipine on Cardiac Iron Overload in Children With Beta Thalassemia
Condition: Beta Thalassemia Major
Interventions: Drug: Spirulina;   Drug: Amlodipine
12 Completed Amlodipine for Myocardial Iron in Thalassemia
Condition: Thalassemia
Interventions: Drug: Standard Chelation;   Drug: Amlodipine
13 Active, not recruiting Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia
Condition: Thalassemia Major With Severe Transfusional Iron Overload
Intervention: Drug: Deferasirox and deferiprone
14 Unknown  Combined Chelation Treatment With Deferiprone and Deferoxamine in Thalassemia Major
Condition: Beta-Thalassemia
Intervention: Drug: deferiprone
15 Active, not recruiting Myelodysplastic Syndromes (MDS) Event Free Survival With Iron Chelation Therapy Study
Condition: Myelodysplastic Syndromes
Interventions: Drug: Deferasirox;   Drug: Deferasirox placebo
16 Not yet recruiting Study of MRI Monitoring in Patients With Aplastic Anemia and Low or Int-1 Risk of MDS Complicated With Iron Overload
Conditions: Aplastic Anemia;   Dysmyelopoietic Syndromes;   Iron Overload
Intervention:
17 Recruiting Screening for Subjects to Participate in Studies of Blood Disorders
Conditions: Bone Marrow Transplant;   Sickle Cell Disease;   G-CSF
Intervention:
18 Completed Combo Chelation Trial
Conditions: Thalassemia;   Iron Overload
Intervention: Drug: Combo Chelation with Deferasirox (Exjade) and Desferal (DFO)
19 Completed Efficacy Study of the Use of Sequential DFP-DFO Versus DFP
Conditions: Beta-Thalassemia;   Thalassemia Major
Interventions: Drug: Deferiprone (DFP) and Deferoxamine (DFO);   Drug: Deferiprone (DFP)
20 Completed MR Imaging of Diffuse Myocardial Fibrosis in Transfusion-Dependent Anemias
Conditions: Thalassemia Major;   Chronic Blood Transfusion Related Iron Overload
Intervention:

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Study has passed its completion date and status has not been verified in more than two years.