173 studies found for:    chelation AND heart
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Rank Status Study
1 Completed
Has Results
Trial to Assess Chelation Therapy (TACT)
Condition: Coronary Artery Disease
Interventions: Drug: EDTA;   Drug: EDTA Placebo;   Dietary Supplement: High Dose Vitamin;   Dietary Supplement: High Dose Vitamin Placebo
2 Completed Intensive Combined Chelation Therapy for Iron-Induced Cardiac Disease in Patients With Thalassemia Major
Conditions: Iron Overload;   Cardiomyopathy
Interventions: Drug: Deferoxamine and Deferiprone;   Drug: Deferoxamine
3 Completed Safety and Efficacy of Deferasirox in Combination With Desferoxamine in β-thalassaemia Patients With Severe Cardiac Iron Overload
Conditions: Transfusion-dependent β-thalassemia Patients;   Cardiac Iron Overload
Interventions: Drug: Deferasirox;   Drug: Deferasirox + Deferoxamine
4 Not yet recruiting Trial to Assess Chelation Therapy 2
Conditions: Diabetes;   Myocardial Infarction
Interventions: Drug: disodium EDTA;   Dietary Supplement: Oral Multi Vitamins/Minerals (OMVM);   Drug: Placebo disodium EDTA;   Dietary Supplement: Placebo Oral Multi Vitamins/Minerals (OMVM)
5 Active, not recruiting Amlodipine as Adjuvant Treatment to Iron Chelation for Prevention of Cardiac Iron Overload in Thalassemia Patients
Conditions: Beta-Thalassemia;   Iron Overload
Interventions: Drug: Amlodipine;   Drug: Deferasirox
6 Completed Efficacy Study in Removing Excess Iron From the Heart
Conditions: Thalassemia Major;   Hemosiderosis
Interventions: Drug: Ferriprox (deferiprone);   Drug: Desferal (deferoxamine)
7 Completed An Epidemiological Study to Assess Iron Overload Using MRI in Patients With Transfusional Siderosis (TIMES Study)
Condition: Thalassemia, NTDT, MDS, MF, Other Anemia
Intervention: Device: MRI scan
8 Completed
Has Results
Evaluating Use of Deferasirox as Compared to Deferoxamine in Treating Cardiac Iron Overload
Conditions: Transfusional Iron Overload;   Transfusional Hemosiderosis
Interventions: Drug: Core Study: Deferasirox;   Drug: Core Study: Deferoxamine;   Drug: Extension: deferoxamine to deferasirox;   Drug: Extension: deferasirox to deferoxamine;   Drug: Deferasirox;   Drug: Deferoxamine
9 Completed Cardiac T2* in Beta-thalassemia Patients on Deferasirox Treatment
Conditions: Beta-thalassemia;   Iron Overload
Intervention: Drug: Deferasirox
10 Recruiting Reproductive Capacity and Iron Burden in Thalassemia
Condition: THALASSEMIA MAJOR
Interventions: Other: Blood Draw/Semen Exam;   Other: Retrospective data/Chart Review/Relevant Clinical Results;   Other: Pituitary MRI
11 Recruiting Evaluation of Myocardial Iron Deposition in Patients of Heart Failure Using T2* MR Imaging
Conditions: Heart Failure;   Iron Overload;   Cardiomyopathies
Intervention: Other: MR T2* imaging
12 Active, not recruiting Cardiac Function in Patients With Hereditary Hemochromatosis
Condition: Hemochromatosis
Intervention:
13 Unknown  Efficacy and Safety of Deferiprone in Patients With Chronic Kidney Disease Undergoing a Cardiac Catheterization and Receiving Contrast Agent
Condition: Acute Kidney Injury
Interventions: Drug: deferiprone;   Drug: Placebo
14 Recruiting Effect of Spirulina Compared to Amlodipine on Cardiac Iron Overload in Children With Beta Thalassemia
Condition: Beta Thalassemia Major
Interventions: Drug: Spirulina;   Drug: Amlodipine
15 Unknown  Combined Chelation Treatment With Deferiprone and Deferoxamine in Thalassemia Major
Condition: Beta-Thalassemia
Intervention: Drug: deferiprone
16 Completed Amlodipine for Myocardial Iron in Thalassemia
Condition: Thalassemia
Interventions: Drug: Standard Chelation;   Drug: Amlodipine
17 Unknown  Clinical Importance of Treating Iron Overload in Sickle Cell Disease
Conditions: Anemia, Sickle Cell;   Transfusion Hemochromatosis
Intervention: Drug: deferasirox
18 Completed Combo Chelation Trial
Conditions: Thalassemia;   Iron Overload
Intervention: Drug: Combo Chelation with Deferasirox (Exjade) and Desferal (DFO)
19 Completed Efficacy of EVP 1001-1 (SeeMore) in the Assessment of Myocardial Viability in Patients With Cardiovascular Disease
Condition: ISCHEMIC CARDIOMYOPATHY
Intervention: Drug: 'SEEMORE' - MANGANESE-ENHANCED MRI CONTRAST REAGENT
20 Active, not recruiting Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia
Condition: Thalassemia Major With Severe Transfusional Iron Overload
Intervention: Drug: Deferasirox and deferiprone

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Indicates status has not been verified in more than two years