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189 studies found for:    cancer | Open Studies | wake forest
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Rank Status Study
21 Recruiting Durvalumab Before Surgery in Treating Patients With Oral Cavity or Oropharynx Cancer
Conditions: Human Papillomavirus Infection;   Stage I Oral Cavity Squamous Cell Carcinoma;   Stage I Oropharyngeal Squamous Cell Carcinoma;   Stage II Oral Cavity Squamous Cell Carcinoma;   Stage II Oropharyngeal Squamous Cell Carcinoma;   Stage III Oral Cavity Squamous Cell Carcinoma;   Stage III Oropharyngeal Squamous Cell Carcinoma;   Stage IVA Oral Cavity Squamous Cell Carcinoma;   Stage IVA Oropharyngeal Squamous Cell Carcinoma;   Stage IVB Oral Cavity Squamous Cell Carcinoma;   Stage IVB Oropharyngeal Squamous Cell Carcinoma;   Stage IVC Oropharyngeal Squamous Cell Carcinoma
Interventions: Biological: Durvalumab;   Other: Laboratory Biomarker Analysis;   Procedure: Therapeutic Conventional Surgery
22 Recruiting Trial of Acupuncture for Radiation-Induced Xerostomia in Head and Neck Cancer
Condition: Radiation-Induced Xerostomia
Interventions: Other: Standard Oral Hygiene;   Other: Standard Oral Hygiene + True Acupuncture;   Other: Standard Oral Hygiene + Sham Acupuncture
23 Recruiting Paclitaxel and Pembrolizumab in Treating Patients With Refractory Metastatic Urothelial Cancer
Condition: Transitional Cell Carcinoma
Interventions: Other: Laboratory Biomarker Analysis;   Drug: Paclitaxel;   Biological: Pembrolizumab
24 Recruiting Omega-3 Fatty Acid in Treating Patients With Stage I-III Breast Cancer
Conditions: Ductal Breast Carcinoma in Situ;   Lobular Breast Carcinoma in Situ;   Male Breast Cancer;   Stage IA Breast Cancer;   Stage IB Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
Interventions: Dietary Supplement: omega-3 fatty acid;   Other: placebo;   Other: laboratory biomarker analysis
25 Recruiting Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis
Conditions: Metastatic Breast Cancer;   Leptomeningeal Disease
Intervention: Drug: High-dose Methotrexate (8 gm/m2; HD-MTX)
26 Not yet recruiting APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by Surgery
Conditions: Metastatic Malignant Neoplasm in the Brain;   Metastatic Solid Neoplasm;   Recurrent Colorectal Carcinoma;   Recurrent Pancreatic Carcinoma;   Recurrent Solid Neoplasm;   Stage IV Colorectal Cancer;   Stage IV Pancreatic Cancer;   Stage IVA Colorectal Cancer;   Stage IVA Pancreatic Cancer;   Stage IVB Colorectal Cancer;   Stage IVB Pancreatic Cancer;   Unresectable Solid Neoplasm
Interventions: Other: Laboratory Biomarker Analysis;   Biological: siRNA-transfected Peripheral Blood Mononuclear Cells APN401
27 Recruiting Bupropion Hydrochloride or Patient's Choice for Smoking Cessation in Patients With Squamous Cell Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy
Conditions: Current Smoker;   Head and Neck Squamous Cell Carcinoma;   Hypopharyngeal Squamous Cell Carcinoma;   Laryngeal Squamous Cell Carcinoma;   Nasopharyngeal Carcinoma;   Oral Cavity Squamous Cell Carcinoma;   Oropharyngeal Squamous Cell Carcinoma
Interventions: Drug: Bupropion Hydrochloride;   Other: Laboratory Biomarker Analysis;   Drug: Nicotine Replacement;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration;   Drug: Varenicline
28 Not yet recruiting Internet-Delivered Positive Affect Program in Managing Emotion in Young Adult Cancer Survivors
Condition: Cancer Survivor
Interventions: Other: Internet-Based Intervention;   Procedure: Quality-of-Life Assessment;   Other: Questionnaire Administration;   Behavioral: Telephone-Based Intervention
29 Recruiting Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Acute Promyelocytic Leukemia
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Adult Acute Promyelocytic Leukemia (M3);   Childhood Acute Promyelocytic Leukemia (M3);   Recurrent Adult Acute Myeloid Leukemia;   Recurrent Childhood Acute Myeloid Leukemia
Interventions: Drug: gemtuzumab ozogamicin;   Other: laboratory biomarker analysis
30 Recruiting Evaluation of Loratadine for G-CSF Induced Bone Pain in Patients With Hematologic Malignancies
Conditions: Leukemia;   Lymphoma
Intervention: Drug: Loratadine
31 Recruiting Palliative Radiation Therapy in Reducing Pain in Patients With Bone Metastasis
Conditions: Malignant Neoplasm;   Metastatic Malignant Neoplasm in the Bone;   Pain
Interventions: Radiation: External Beam Radiation Therapy;   Radiation: Palliative Radiation Therapy;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration
32 Recruiting Qualitative, Qualitative, and Functional Studies Over the First Year in Measuring Immune System Response During the First Year of Therapy in Patients With Brain Tumors
Conditions: Astrocytoma;   Glioma;   Oligodendroglioma
Interventions: Biological: Hepatitis A Vaccine;   Other: Laboratory Biomarker Analysis;   Biological: Tetanus Toxoid Vaccine;   Biological: Trivalent Influenza Vaccine
33 Not yet recruiting Preparatory Work to Assess Adherence to Oral Chemotherapy
Condition: Chronic Myeloid Leukemia
Intervention:
34 Recruiting Donor Stem Cell Transplant Followed by Cyclophosphamide in Treating Patients With Hematological Diseases
Conditions: Graft Versus Host Disease;   Hematopoietic/Lymphoid Cancer
Interventions: Drug: fludarabine phosphate;   Drug: busulfan;   Drug: cyclophosphamide;   Procedure: allogeneic hematopoietic stem cell transplantation;   Drug: tacrolimus;   Drug: mycophenolate mofetil
35 Recruiting CIP-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Granulocytic Sarcoma
Conditions: Granulocytic Sarcoma;   Recurrent Adult Acute Myeloid Leukemia
Interventions: Drug: 6,8-Bis(benzylthio)octanoic Acid;   Drug: Cytarabine;   Procedure: Hematopoietic Cell Transplantation;   Drug: Mitoxantrone Hydrochloride
36 Not yet recruiting Simvastatin in Overcoming Chemotherapy Resistance in Patients With Relapsed or Refractory Multiple Myeloma
Conditions: Recurrent Plasma Cell Myeloma;   Refractory Plasma Cell Myeloma
Interventions: Other: Laboratory Biomarker Analysis;   Other: Quality-of-Life Assessment;   Drug: Simvastatin
37 Not yet recruiting Phase 3 Randomized Placebo Controlled Clinical Trial of Donepezil - WF 97116
Conditions: Cognitive Dysfunction;   Memory Impairment
Interventions: Drug: Donepezil 5 mg;   Drug: Placebo
38 Recruiting The Use of Integra in Coverage of Radial Forearm Free Flap Donor Site Defect
Condition: Head and Neck Cancer
Interventions: Device: Integra plus STSG;   Procedure: STSG
39 Not yet recruiting Selinexor With Induction, Consolidation, and Maintenance Therapy in Treating Older Patients With Acute Myeloid Leukemia
Condition: Untreated Adult Acute Myeloid Leukemia
Interventions: Drug: Cytarabine;   Drug: Daunorubicin Hydrochloride;   Drug: Selinexor
40 Recruiting CPI-613 in Treating Patients With Myelodysplastic Syndromes Who Failed Previous Therapy
Condition: Previously Treated Myelodysplastic Syndromes
Intervention: Drug: 6,8-bis(benzylthio)octanoic acid

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Study has passed its completion date and status has not been verified in more than two years.