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147 studies found for:    c1 inhibitor
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Study Details
Participant Details
Identifiers
Dates
Rank Status Study
1 Completed
Has Results
Safety & Tolerability of Berinert® (C1 Inhibitor) Therapy to Prevent Rejection
Condition: Kidney Transplantation
Intervention: Drug: C1 Esterase Inhibitor
2 Completed Berinert P Study of Subcutaneous Versus Intravenous Administration
Condition: Hereditary Angioedema
Intervention: Drug: C1-Esterase Inhibitor
3 Completed Patient Registry Study of Berinert® in Normal Clinical Practice
Condition: Includes: Hereditary Angioedema
Intervention: Biological: Berinert® (C1 Esterase Inhibitor)
4 Completed
Has Results
C1 Esterase Inhibitor in Hereditary Angioedema (HAE)(Extension Study)
Condition: Hereditary Angioedema
Intervention: Drug: C1 Esterase Inhibitor
5 Completed
Has Results
Postmarketing Immunogenicity Study in HAE Subjects Treated With Berinert
Condition: Hereditary Angioedema Types I and II
Intervention: Biological: Berinert, lyophilizate for IV application containing 500 IU C1-INH to be reconstituted with 10 mL water for injection
6 Completed A Study to Evaluate the Safety and Pharmacokinetics of Two Formulations of C1-esterase Inhibitor
Condition: Hereditary Angioedema Types I and II
Interventions: Biological: Berinert;   Biological: CSL830
7 Completed
Has Results
Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema
Conditions: Hereditary Angioedema;   Angioneurotic Edema
Interventions: Drug: Recombinant Human C1 Inhibitor;   Drug: placebo
8 Recruiting C1INH Inhibitor Preoperative and Post Kidney Transplant to Prevent DGF & IRI
Conditions: End Stage Renal Disease;   Kidney Failure;   Delayed Graft Function;   Ischemic Reperfusion Injury
Interventions: Drug: C1 Esterase Inhibitor;   Drug: Placebo
9 Completed In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia
Conditions: Endotoxemia;   Inflammation;   Multi Organ Dysfunction Syndrome
Interventions: Drug: C1-esterase inhibitor;   Drug: Endotoxin administration
10 Completed
Has Results
Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema
Conditions: Hereditary Angioedema;   Angioneurotic Edema;   Genetic Disorders
Interventions: Drug: recombinant human C1 inhibitor;   Drug: Placebo
11 Terminated Effect of C1-esterase Inhibitor on Systemic Inflammation in Trauma Patients With a Femur or Pelvic Fracture
Conditions: Trauma;   Inflammation;   Sepsis;   Multiple Organ Dysfunction Syndrome
Interventions: Drug: C1-esterase inhibitor;   Other: Saline 0.9%
12 Completed Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema
Condition: Genetic Disorders
Intervention: Drug: i.v. recombinant human C1 inhibitor
13 Completed Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema
Condition: Genetic Disorders
Intervention: Drug: i.v. recombinant human C1 inhibitor
14 Completed
Has Results
A Study of the Safety and Immunogenicity of Repeated rhC1INH Administration
Conditions: Genetic Disorders;   Hereditary Angioedema
Intervention: Drug: Recombinant Human C1 Inhibitor
15 Completed In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia - VECTOR II
Conditions: Innate Immune Response;   Endotoxemia;   Inflammation;   Sepsis
Interventions: Drug: C1-esterase inhibitor;   Drug: Endotoxin
16 Recruiting C1 Inhibitor Registry in the Treatment of Hereditary Angioedema (HAE) Attacks
Condition: Hereditary Angioedema
Intervention: Drug: rhC1INH or pdC1INH
17 Completed A Phase 2 HAE Prophylaxis Study With Recombinant Human C1 Inhibitor
Condition: Hereditary Angioedema
Interventions: Biological: Recombinant human C1 inhibitor;   Other: Placebo
18 Completed
Has Results
Human C1 Esterase Inhibitor (C1-INH) in Subjects With Acute Abdominal or Facial Hereditary Angioedema (HAE) Attacks
Condition: Hereditary Angioedema
Interventions: Biological: C1 Esterase Inhibitor;   Biological: Placebo
19 Completed A Study to Evaluate the Clinical Pharmacology and Safety of C1-esterase Inhibitor Administered by the Subcutaneous Route
Condition: Hereditary Angioedema Types I and II
Interventions: Biological: C1-esterase inhibitor - single intravenous dose;   Biological: C1-esterase inhibitor - subcutaneous low dose;   Biological: C1-esterase inhibitor - subcutaneous medium dose;   Biological: C1-esterase inhibitor - subcutaneous high dose
20 Active, not recruiting Study to Evaluate the Clinical Efficacy and Safety of Subcutaneously Administered C1 Esterase Inhibitor for the Prevention of Angioedema Attacks in Adolescents and Adults With Hereditary Angioedema
Condition: Hereditary Angioedema (HAE)
Intervention: Drug: C1 esterase inhibitor [human] liquid

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Study has passed its completion date and status has not been verified in more than two years.