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239 studies found for:    breast cancer targeted therapy | Open Studies
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Rank Status Study
1 Recruiting Molecular Mechanisms of Clinical Resistance to Targeted Therapy Among Patients With Breast Cancer
Condition: Breast Cancer
Interventions: Other: Blood draw;   Other: immunoenzyme technique;   Procedure: biopsy;   Procedure: histopathologic examination
2 Recruiting Treatment of Canadian Postmenopausal Women With ER+ Advanced Breast Cancer in the Real-World Setting With Hormone Therapy ± Targeted Therapy
Condition: HR+ HER2- Postmenopausal Advanced Breast Cancer
Interventions: Drug: Endocrine therapy may include one of the following therapies: letrozole, anastrozole, exemestane, tamoxifen or fulvestrant;   Drug: Endocrine therapy in combination with targeted therapy may include: everolimus plus exemestane or CDK4/6 inhibitor plus endocrine therapy
3 Recruiting A Clinical Trial Evaluating the Safety and Clinical Activity of Radioiodide (131I-) as a Novel Targeted Therapy for Metastatic Breast Cancer That Overexpresses Functional Na/I Symporter
Condition: Breast Cancer
Intervention: Radiation: Radioiodide (131I-)
4 Recruiting Cardiac Safety Study in Patients With HER2 + Breast Cancer
Conditions: HER2 Positive Breast Cancer;   Left Ventricular Function Systolic Dysfunction
Intervention: Drug: Trastuzumab, Pertuzumab, Ado-trastuzumab emtansine
5 Recruiting Genome Sequencing in Refractory Breast Cancer to Molecular Targeted Therapy and Young Breast Cancer
Condition: Breast Cancer
6 Recruiting To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Conditions: Breast Cancer;   Solid Tumor
Interventions: Drug: GDC-0077;   Drug: Fulvestrant;   Drug: Letrozole;   Drug: Palbociclib
7 Recruiting Genomic and Proteomic Profiling Targets Influenced Treatment in Metastatic Breast Cancer
Conditions: Breast Cancer;   Breast Tumor;   Gynecologic Cancer
Intervention: Genetic: Genetic profiling
8 Recruiting Detect V / CHEVENDO (Chemo vs. Endo)
Condition: Metastatic Breast Cancer
Interventions: Drug: pertuzumab;   Drug: Trastuzumab;   Drug: Capecitabine;   Drug: Paclitaxel;   Drug: Vinorelbine;   Drug: Docetaxel;   Drug: Exemestane;   Drug: Letrozole;   Drug: Anastrozole;   Drug: Fulvestrant;   Drug: Tamoxifen
9 Not yet recruiting Randomized, Open Label, Clinical Study of the Targeted Therapy, Palbociclib, to Treat Metastatic Breast Cancer
Conditions: HER-2 Positive Breast Cancer;   Estrogen Receptor Positive Breast Cancer
Interventions: Drug: palbociclib;   Drug: trastuzumab;   Drug: pertuzumab;   Drug: letrozole;   Drug: Anastrozole;   Drug: Exemestane;   Drug: Fulvestrant
10 Recruiting Clinical Application of Dual Sentinel Lymph Node Staining Method in Breast Cancer Patients
Condition: Breast Cancer
Interventions: Drug: Indocyanine green;   Drug: Radioisotope
11 Not yet recruiting Adapted Physical Activity for Breast Cancer HER2 Positive Patient
Condition: HER2 Positive Breast Cancer
Intervention: Other: Home-based Adapted Physical Activity
12 Recruiting [18F]FES PET/CT in Endocrine Refractory Breast Cancer
Conditions: Estrogen Receptor Positive Breast Cancer;   Breast Neoplasm;   Metastatic Breast Cancer
Intervention: Drug: [18F]FES
13 Recruiting Arimidex With or Without Faslodex In Postmenopausal Women With HR Positive Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Arimidex with Faslodex;   Drug: Arimidex without Faslodex
14 Recruiting [18F]Fluoroestradiol (FES) PET/CT Imaging to Evaluate in Vivo Estrogen Receptor Activity in Endocrine Refractory Recurrent or Metastatic Breast Cancer
Conditions: Recurrent ER+ Breast Cancer;   Metastatic ER+ Breast Cancer
Intervention: Radiation: [18F]Fluoroestradiol (FES) PET/CT Imaging
15 Recruiting Adjuvant Dynamic Marker-Adjusted Personalized Therapy Trial Optimizing Risk Assessment and Therapy Response Prediction in Early Breast Cancer
Condition: Breast Cancer
Intervention: Other: Induction therapy
16 Not yet recruiting Effect of High Dose Vitamin D on Cancer Biomarkers and Breast Cancer Tumors
Conditions: Breast Cancer;   Invasive Breast Carcinoma;   Ductal Carcinoma In-situ
Intervention: Drug: Vitamin D3
17 Recruiting Phase I Study of Pyrotinib in Patients With HER2-positive Solid Tumors
Conditions: Breast Cancer;   Gastric Cancer;   Solid Tumors;   NSCLC
Intervention: Drug: Pyrotinib
18 Recruiting DETECT III - A Multicenter, Phase III Study to Compare Standard Therapy +/- Lapatinib in HER2-ve MBC-Patients With HER2+ve CTCs
Conditions: HER2-negative Metastatic Breast Cancer;   HER2-positive Circulating Tumor Cells
Interventions: Drug: standard chemo- or endocrine therapy;   Drug: standard chemo- or endocrine therapy + Lapatinib
19 Recruiting Neoadjuvant Chemotherapy for Operable Premenopausal Breast Cancer Patients
Condition: Breast Cancer Nos Premenopausal
Interventions: Drug: Docetaxel;   Drug: epirubicin;   Drug: cyclophosphamide;   Procedure: Modified radical mastectomy or breast-conserving Surgery;   Drug: Docetaxel (post-operative);   Drug: Epirubicin (post-operative);   Drug: Cyclophosphamide (post-operative);   Radiation: Radiation therapy;   Drug: Herceptin (post-operative);   Drug: Tamoxifen (post-operative)
20 Recruiting Pilot Study of Veliparib (ABT-888) and Lapatinib (Tykerb) in Patients With Metastatic, Triple Negative Breast Cancer
Condition: Metastatic Triple Negative Breast Cancer
Intervention: Drug: Combination of Veliparib + Lapatinib

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Study has passed its completion date and status has not been verified in more than two years.