Try our beta test site
IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...
20 studies found for:    breast cancer AND premenopausal | Open Studies | United States
Show Display Options
Rank Status Study
1 Recruiting Examination of Breast Cancer Cells of Pre-menopausal Women Before and After Exposure to Tamoxifen or Fulvestrant.
Condition: Breast Cancer
Interventions: Drug: Fulvestrant;   Drug: Tamoxifen
2 Recruiting Serum Biomarkers to Characterize the Effects of Therapy on Ovarian Reserve in Premenopausal Women With Early-stage Breast Cancer or BRCA Mutations
Condition: Breast Cancer
Intervention: Other: Blood draw and questionnaires
3 Recruiting Phase I Study of Combination of Gedatolisib With Palbociclib and Faslodex in Patients With ER+/HER2- Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Gedatolisib;   Drug: Faslodex;   Drug: Palbociclib;   Drug: Zoladex
4 Recruiting Phase II Study of Metformin for Reduction of Obesity-Associated Breast Cancer Risk
Condition: Breast Cancer Prevention
Interventions: Drug: Metformin;   Drug: Placebo
5 Recruiting Endocrine Response in Women With Invasive Lobular Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Tamoxifen;   Drug: Anastrozole;   Drug: Fulvestrant
6 Recruiting High-Risk Breast Duct Epithelium
Condition: Breast Cancer
Intervention:
7 Recruiting 19F Hot Spot MRI of Human Adipose-derived Stem Cells for Breast Reconstruction
Condition: Breast Cancer
Intervention: Drug: CS-1000 labeled SVF cells
8 Recruiting Longitudinal Sexual and Reproductive Health Study of Women With Breast Cancer and Lymphoma
Conditions: Breast Cancer;   Lymphoma;   Hodgkin's Lymphoma
Interventions: Behavioral: surveys;   Other: Blood draw;   Device: Transvaginal ultrasounds
9 Not yet recruiting Neoadjuvant Study of Palbociclib in Combination With Letrozole and Trastuzumab in Stage II-III ER+ HER2+ Breast Cancer
Conditions: Breast Cancer;   Cancer of Breast;   Breast Carcinoma
Interventions: Drug: Palbociclib;   Drug: Letrozole;   Biological: Trastuzumab;   Drug: Goserelin;   Procedure: Breast surgery;   Procedure: Research tumor biopsy;   Procedure: Research bone marrow (OPTIONAL);   Procedure: Research blood sample;   Genetic: Research blood for germline DNA
10 Recruiting NEOADjuvant Aromatase Inhibitor and Pertuzumab/Trastuzumab for Women With Breast Cancer
Condition: Breast Neoplasms
Interventions: Drug: Exemestane;   Drug: Letrozole;   Drug: Anastrozole;   Drug: Leuprolide Acetate;   Drug: Pertuzumab;   Drug: Trastuzumab
11 Recruiting The Immune System's Response to Young Women's Breast Cancer
Conditions: Breast Cancer;   Breast Cancer and Pregnancy
Intervention:
12 Recruiting Compare Daily Ulipristal Acetate and Combined Oral Contraceptive Effects on Breast Epithelial Cell Proliferation
Condition: Contraception
Interventions: Drug: Ulipristal Acetate;   Drug: Combined Oral Contraceptive Pill
13 Recruiting Metformin Hydrochloride in Patients With Atypical Hyperplasia or In Situ Breast Cancer to Placebo in Decreasing Atypical Cells in Patients With Atypical Hyperplasia or in Situ Breast Cancer
Conditions: Atypical Ductal Breast Hyperplasia;   BRCA1 Mutation Carrier;   BRCA2 Mutation Carrier;   Ductal Breast Carcinoma in Situ;   Lobular Breast Carcinoma in Situ
Interventions: Drug: metformin hydrochloride;   Other: placebo
14 Recruiting PD 0332991 and Anastrozole for Stage 2 or 3 Estrogen Receptor Positive and HER2 Negative Breast Cancer
Condition: Breast Neoplasms
Interventions: Drug: PD0332991;   Drug: Anastrozole;   Drug: Goserelin;   Procedure: Surgery (standard of care);   Procedure: Tumor biopsy
15 Recruiting Transdermal or Oral Telapristone Acetate in Treating Patients Undergoing Mastectomy
Conditions: BRCA1 Mutation Carrier;   BRCA2 Mutation Carrier;   Ductal Breast Carcinoma In Situ;   Lobular Breast Carcinoma In Situ;   Stage 0 Breast Cancer;   Stage IA Breast Cancer;   Stage IB Breast Cancer;   Stage IIA Breast Cancer;   Stage IIB Breast Cancer
Interventions: Drug: Telapristone Acetate;   Other: Placebo;   Other: Laboratory Biomarker Analysis;   Other: Questionnaire Administration
16 Recruiting A Study of Palbociclib in Combination With Fulvestrant or Tamoxifen as Treatment for Metastatic Breast Cancer
Conditions: Metastatic Breast Cancer;   Hormone Receptor Positive
Intervention: Drug: Palbociclib
17 Recruiting Safety and Immune Response to a Mammaglobin-A DNA Vaccine In Breast Cancer Patients Undergoing Neoadjuvant Endocrine Therapy
Conditions: Breast Cancer;   Breast Carcinoma;   Malignant Neoplasm of Breast
Interventions: Biological: Mammaglobin-A DNA Vaccine;   Drug: Anastrozole;   Drug: Letrozole;   Drug: Tamoxifen;   Drug: Exemestane;   Drug: Goserelin
18 Recruiting Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer
Condition: Early Breast Cancer
Intervention: Other: Endocrine therapy interruption
19 Recruiting Study to Assess the Safety and Efficacy of Ribociclib (LEE011) in Combination With Letrozole for the Treatment of Men and Pre/Postmenopausal Women With HR+ HER2- aBC
Condition: Breast Cancer
Interventions: Drug: Ribociclib (LEE011);   Drug: Letrozole;   Drug: Goserelin
20 Recruiting A Companion Sample Collection Protocol to Support the Discovery of Breast Cancer Aberrations With Treatment of CDK4/6 Therapy/LEE011/Ribociclib
Condition: Breast Cancer
Interventions: Drug: Ribociclib;   Drug: letrozole

Study has passed its completion date and status has not been verified in more than two years.