1847 studies found for:    breast,cancer,treatment | Open Studies
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Rank Status Study
1 Recruiting A Clinical Trial to Assess the Safety of 0.005 % Estriol Vaginal Gel in Hormone Receptor-Positive Postmenopausal Women With Early Stage Breast Cancer in Treatment With Aromatase Inhibitor in the Adjuvant Setting
Condition: Vaginal Atrophy
Interventions: Drug: estriol;   Drug: Placebo
2 Recruiting Docetaxel, Carboplatin, Trastuzumab, and Pertuzumab With or Without Estrogen Deprivation in Treating Patients With Hormone Receptor-Positive, HER2-Positive Operable or Locally Advanced Breast Cancer
Conditions: Estrogen Receptor Positive;   HER2/Neu Positive;   Progesterone Receptor Positive;   Stage IB Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
Interventions: Drug: Aromatase Inhibition Therapy;   Drug: Carboplatin;   Other: Cytology Specimen Collection Procedure;   Drug: Docetaxel;   Drug: Goserelin Acetate;   Other: Laboratory Biomarker Analysis;   Biological: Pertuzumab;   Other: Quality-of-Life Assessment;   Procedure: Therapeutic Conventional Surgery;   Biological: Trastuzumab;   Radiation: Whole Breast Irradiation
3 Recruiting POSNOC - A Trial Looking at Axillary Treatment in Early Breast Cancer
Condition: Breast Cancer
Interventions: Other: Adjuvant therapy;   Procedure: Axillary treatment
4 Recruiting Supervised Aerobic Training During or After Adjuvant Therapy for Operable Breast Cancer
Condition: Breast Cancer
Interventions: Behavioral: Aerobic Therapy;   Behavioral: Educational Information
5 Not yet recruiting Breast-Conserving Therapy in Patients With Triple-Negative Breast Cancer
Condition: Breast Cancer
Interventions: Procedure: Breast-Conserving Therapy;   Procedure: Mastectomy;   Drug: Adjuvant Chemotherapy;   Radiation: Radiation Therapy
6 Recruiting A Pilot Study Utilizing Proteomic and Genomic Profiling for Patients With Metastatic Breast Cancer
Condition: Metastatic Breast Cancer
Intervention: Other: treated recommended
7 Recruiting Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy
Conditions: Stage II Breast Cancer;   Stage IIIA Breast Cancer
Interventions: Procedure: Axillary Lymph Node Dissection (ALND);   Radiation: Nodal Radiation Therapy;   Radiation: Axillary Radiation Therapy
8 Not yet recruiting Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score
Conditions: Breast Cancer;   Cancer of Breast;   Breast Neoplasms;   Cancer of the Breast
Interventions: Device: Oncotype DX® Breast Cancer Assay;   Behavioral: FACT-B;   Drug: Goserelin;   Drug: Anastrozole;   Drug: Exemestane;   Drug: Fulvestrant;   Drug: Tamoxifen
9 Not yet recruiting Intensity Modulated Accelerated Partial Breast Irradiation Before Surgery in Treating Older Patients With Hormone Responsive Stage 0-I Breast Cancer
Conditions: Ductal Breast Carcinoma in Situ;   Estrogen Receptor-negative Breast Cancer;   Estrogen Receptor-positive Breast Cancer;   Invasive Ductal Breast Carcinoma;   Invasive Ductal Breast Carcinoma With Predominant Intraductal Component;   Lobular Breast Carcinoma in Situ;   Medullary Ductal Breast Carcinoma With Lymphocytic Infiltrate;   Mucinous Ductal Breast Carcinoma;   Papillary Ductal Breast Carcinoma;   Progesterone Receptor-positive Breast Cancer;   Stage IA Breast Cancer;   Stage IB Breast Cancer;   Tubular Ductal Breast Carcinoma
Interventions: Radiation: accelerated partial breast irradiation;   Radiation: intensity-modulated radiation therapy;   Radiation: image-guided radiation therapy;   Procedure: therapeutic conventional surgery;   Other: questionnaire administration;   Other: laboratory biomarker analysis
10 Recruiting Exemestane With or Without Entinostat in Treating Postmenopausal Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic
Conditions: Estrogen Receptor Positive;   HER2/Neu Negative;   Hormone-Resistant Breast Cancer;   Male Breast Carcinoma;   Progesterone Receptor Positive;   Recurrent Breast Carcinoma;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer;   Stage IV Breast Cancer
Interventions: Drug: Entinostat;   Drug: Exemestane;   Drug: Goserelin Acetate;   Other: Laboratory Biomarker Analysis;   Other: Placebo;   Other: Quality-of-Life Assessment
11 Recruiting MRI and Gene Expression in Diagnosing Patients With Ductal Breast Cancer In Situ
Condition: Ductal Breast Carcinoma In Situ
Interventions: Procedure: Magnetic Resonance Imaging;   Procedure: Therapeutic Conventional Surgery;   Procedure: Therapeutic Surgical Procedure;   Radiation: Radiation Therapy;   Drug: Endocrine Therapy;   Other: Quality-of-Life Assessment;   Other: Laboratory Biomarker Analysis;   Other: Cytology Specimen Collection Procedure
12 Recruiting Early Surgery or Standard Palliative Therapy in Treating Patients With Stage IV Breast Cancer
Condition: Breast Cancer
Interventions: Procedure: palliative surgery;   Procedure: therapeutic conventional surgery;   Radiation: palliative radiation therapy;   Radiation: radiation therapy
13 Recruiting Efficacy Study of Herceptin to Treat HER2-negative CTC Breast Cancer
Conditions: Breast Cancer;   Human Epidermal Growth Factor 2 Negative Carcinoma of Breast;   Circulating Tumor Cells
Intervention: Drug: trastuzumab
14 Recruiting Akt Inhibitor MK-2206 and Anastrozole With or Without Goserelin Acetate in Treating Patients With Stage II-III Breast Cancer
Conditions: Estrogen Receptor Positive;   HER2/Neu Negative;   Recurrent Breast Carcinoma;   Stage IIA Breast Cancer;   Stage IIB Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
Interventions: Drug: Akt Inhibitor MK2206;   Drug: Anastrozole;   Drug: Goserelin Acetate;   Other: Laboratory Biomarker Analysis;   Procedure: Neoadjuvant Therapy;   Other: Pharmacological Study;   Procedure: Therapeutic Conventional Surgery
15 Recruiting A Pharmacokinetic and Randomized Trial of Neoadjuvant Treatment With Anastrozole Plus AZDO530 in Postmenopausal Patients With Hormone Receptor Positive Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Anastrozole;   Drug: ADZ0530;   Drug: Placebo;   Procedure: Pharmacokinetic studies;   Procedure: Definitive Surgery;   Procedure: Core Biopsy;   Genetic: Tumor Tissue Collection for Genetic and Molecular Studies
16 Recruiting Homologous Recombination Repair Status as a Biomarker of Response in Locally Recurrent/Metastatic Triple Negative Breast Cancer Patients Treated With Concurrent Cisplatin and Radiation Therapy
Condition: Locally Recurrent/Metastatic Triple Negative Breast Cancer
Interventions: Radiation: external beam radiation therapy;   Drug: cisplatin;   Procedure: Biopsy of Target Tumor
17 Recruiting Aggressive Local Therapy for Limited Bone-only Metastasis
Condition: Breast Cancer
Interventions: Drug: Standard Therapy;   Procedure: Local Therapy
18 Recruiting Omitting Completion Axillary Treatment in Sentinel Node Positive Breast Cancer Patients Undergoing a Mastectomy
Condition: Breast Neoplasms
Intervention: Procedure: Completion axillary treatment
19 Recruiting Intraoperative Radiation Therapy in Early Stage Breast Cancer
Condition: Breast Cancer
Intervention: Radiation: Intraoperative Radiation Therapy
20 Recruiting Randomized Controlled Trial of Genomically Directed Therapy in Patients With Triple Negative Breast Cancer
Conditions: Malignant Neoplasm of Breast;   Breast Cancer
Interventions: Drug: Genomically Directed Monotherapy;   Other: Observation/Standard Therapy

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