Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
14630 studies found for:    brain
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Rank Status Study
1 Completed
Has Results
Whole Brain Radiotherapy With or Without Temozolomide at Daily Fixed-dose for Brain Metastases Treatment
Condition: Brain Neoplasms
Interventions: Drug: Temozolomide;   Radiation: Whole brain irradiation
2 Recruiting Physiological Brain Atlas Development
Conditions: Parkinson's Disease;   Dystonia;   Essential Tremor;   OCD
Intervention: Device: Deep Brain Stimulator
3 Withdrawn Evaluation of Cabazitaxel in Patients With Brain Metastasis Secondary to Breast Cancer and NSCLC
Conditions: Brain Metastasis;   Breast Cancer;   Non Small Cell Lung Cancer
Interventions: Drug: Cabazitaxel;   Procedure: Contrast-enhanced whole brain MRI
4 Unknown  Icotinib Treat the Patient With Brain Metastasis Epidermal Growth Factor Receptor(EGFR) Mutant Non Small Cell Lung Cancer Comparing With Whole Brain Radiotherapy
Conditions: Brain Metastasis;   Non Small Cell Lung Cancer
Interventions: Radiation: whole brain radiation(WBI);   Drug: Icotinib
5 Not yet recruiting Hippocampal Sparing Whole Brain Radiotherapy vs Conventional Whole Brain Radiotherapy in Patients With Brain Metastases
Condition: Brain Metastases
Interventions: Radiation: Hippocampal sparing whole brain radiotherapy;   Radiation: Conventional whole brain radiotherapy
6 Recruiting Trametinib With or Without Whole Brain Radiation Therapy in Treating Patients With Brain Metastases
Condition: Metastatic Malignant Neoplasm to the Brain
Interventions: Drug: Trametinib;   Radiation: Whole-Brain Radiotherapy;   Procedure: Therapeutic Conventional Surgery;   Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study
7 Active, not recruiting Volumetric Modulated Arc Therapy (VMAT) for Brain Metastases
Condition: Brain Metastases
Intervention: Radiation: whole brain radiotherapy (WBRT) and a simultaneous integrated boost (SIB) using volumetric modulated arc therapy
8 Not yet recruiting Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain Metastases
Conditions: Cognitive Impairment;   Metastatic Malignant Neoplasm to the Brain
Interventions: Drug: Memantine Hydrochloride;   Radiation: Whole-Brain Radiotherapy (WBRT);   Radiation: Hippocampal Avoidance Whole-Brain Radiotherapy (HA-WBRT);   Radiation: Intensity-Modulated Radiation Therapy (IMRT);   Other: Cognitive Assessment;   Other: Quality-of-Life Assessment
9 Completed Prospective Randomized Study of Brain Protection During Aortic Arch Replacement
Condition: Aneurysm of Aortic Arch
Interventions: Procedure: Retrograde brain perfusion;   Procedure: Antegrade brain perfusion
10 Recruiting MRI Study of Changes in Blood-Brain/Tumor-Barrier Permeability in Patients With Brain Metastases During and After Radiotherapy
Condition: Brain Metastases
Interventions: Radiation: Single Fraction Stereotactic Radiosurgery (SRS);   Radiation: Fractionated Whole Brain Radiation Therapy (WBRT);   Radiation: Fractionated Stereotactic Radiation Therapy (FSRT);   Device: Magnetic Resonance Imaging (MRI) Assessments
11 Recruiting Neurocognitive Outcomes In Patients Treated With Radiotherapy For Five Or More Brain Metastases
Condition: Brain Metastases
Interventions: Radiation: Stereotactic radiosurgery (SRS);   Radiation: Whole brain radiation therapy (WBRT)
12 Recruiting Erlotinib With Concurrent Brain Radiotherapy and Secondary Brain Radiotherapy After Recurrence With Erlotinib in NSCLC Non-increased-intracranial-pressure Symptomatic Brain Metastases
Conditions: Non-small-cell Lung Cancer;   Brain Metastases
Interventions: Drug: Erlotinib;   Radiation: concurrent brain radiotherapy;   Radiation: secondary brain radiotherapy
13 Completed Brain Injury Inpatient Educational Intervention for Families and Caregivers
Conditions: Traumatic Brain Injury;   Acquired Brain Injury
Intervention: Behavioral: Brain Injury Education
14 Unknown  Whole-Brain Radiotherapy (WBRT) Versus WBRT and Integrated Boost Using Helical Tomotherapy for Multiple Brain Metastases
Condition: Brain Metastases
Interventions: Radiation: whole brain radiotherapy;   Radiation: whole brain radiotherapy with simultaneous boost
15 Unknown  Stereotactic Radiotherapy of Resection Cavity For Single Brain Metastasis Versus Whole-Brain Radiotherapy After Resection
Condition: Brain Metastases
Interventions: Radiation: stereotactic body radiotherapy (SBRT);   Radiation: Whole-Brain Radiotherapy (WBRT)
16 Active, not recruiting
Has Results
Neurocognitive Evaluation of Mild Traumatic Brain Injury in the Hospitalized Pediatric Population
Conditions: Mild Traumatic Brain Injury;   Concussion
Intervention: Other: Immediate Post-concussion Assessment and Cognitive Testing
17 Recruiting Whole-Brain Radiation Therapy With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer
Conditions: HER2/Neu Positive;   Male Breast Carcinoma;   Metastatic Malignant Neoplasm to the Brain;   Recurrent Breast Carcinoma;   Stage IV Breast Cancer
Interventions: Drug: Lapatinib Ditosylate;   Radiation: Whole-Brain Radiotherapy;   Other: Laboratory Biomarker Analysis
18 Recruiting A Prospective Phase III Trial to Compare Stereotactic Radiosurgery Versus Whole Brain Radiation Therapy
Condition: Brain Neoplasms
Interventions: Radiation: Stereotactic Radiosurgery (SRS);   Radiation: Whole Brain Radiation Therapy (WBRT);   Behavioral: Questionnaires;   Behavioral: Cognitive Function Tests
19 Recruiting Brain Training to Enhance Frontal Lobe Reasoning
Condition: Traumatic Brain Injury
Interventions: Behavioral: Brain Training Program 1;   Behavioral: Brain Training Program 2
20 Completed Study to Demonstrate the Safety of WBR Administered at the Same Time as Intrathecal Liposomal Cytarabine (DepoCyte®) Versus Intrathecal Liposomal Cytarabine (DepoCyte®) Administered After WBR for the Treatment of Solid Tumour Neoplastic Meningitis in Patients With or Without Brain Metastasis.
Conditions: Solid Tumour Neoplastic Meningitis;   Brain Metastases
Interventions: Drug: Whole Brain Radio Therapy (WBRT) with sequential Depocyte;   Drug: Whole brain radiotherapy (WBRT) with concomitant Depocyte

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Indicates status has not been verified in more than two years