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14 studies found for:    akebia
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Rank Status Study
1 Recruiting Dose-Finding Study of Vadadustat in Japanese Subjects With Anemia Secondary to Dialysis-Dependent Chronic Kidney Disease (DD-CKD)
Condition: Anemia; Dialysis Dependent Chronic Kidney Disease
Interventions: Drug: Vadadustat;   Drug: Placebo
2 Recruiting Dose-Finding Study of Vadadustat in Japanese Subjects With Anemia Secondary to Non-Dialysis Dependent Chronic Kidney Disease (NDD-CKD)
Condition: Anemia; Non-dialysis Dependent Chronic Kidney Disease
Interventions: Drug: Vadadustat;   Drug: Placebo
3 Completed Effect of AKB-6548 on Cardiac Repolarization Intervals in Healthy Volunteers
Condition: Healthy Volunteers
Interventions: Drug: AKB-6548 (therapeutic dose);   Drug: AKB-6548 (supratherapeutic dose);   Drug: Placebo;   Drug: Moxifloxacin
4 Recruiting Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Subjects With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)
Conditions: Anemia;   Non-dialysis-dependent Chronic Kidney Disease
Interventions: Drug: vadadustat;   Drug: darbepoetin alfa
5 Recruiting Efficacy and Safety Study to Evaluate Vadadustat for the Correction of Anemia in Subjects With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)
Conditions: Anemia;   Non-dialysis-dependent Chronic Kidney Disease
Interventions: Drug: vadadustat;   Drug: darbepoetin alfa
6 Completed 16-Week Repeat Oral Dose Study of AKB-6548 for Anemia in Subjects With End Stage Renal Disease (ESRD) Requiring Chronic Hemodialysis
Conditions: Anemia;   End Stage Renal Disease
Intervention: Drug: AKB-6548
7 Completed 20-Week Repeat Oral Dose Study of AKB-6548 in Subjects With Chronic Kidney Disease and Anemia
Conditions: Anemia;   Chronic Kidney Disease
Interventions: Drug: AKB-6548;   Drug: Placebo
8 Completed 42-Day Repeat Oral Dose Study of AKB-6548 in Subjects With Chronic Kidney Disease and Anemia
Conditions: Anemia;   Kidney Disease
Interventions: Drug: AKB-6548;   Drug: Placebo
9 Completed Safety and Efficacy Study for AKB-6548 in Subjects With Chronic Kidney Disease and Anemia
Conditions: Anemia;   Kidney Disease
Intervention: Drug: AKB-6548
10 Recruiting Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Subjects With Dialysis-dependent Chronic Kidney Disease (DD-CKD)
Condition: Anemia in Subjects With DD-CKD
Interventions: Drug: vadadustat;   Drug: darbepoetin alfa
11 Completed Effect of AKB-6548 on the Pharmacokinetics of Celecoxib
Condition: Healthy Volunteers
Interventions: Drug: Celecoxib;   Drug: AKB-6548
12 Completed Relative Bioavailability of Two Formulations of AKB-6548 and the Food Effect of a New Tablet in Healthy Adult Subjects
Condition: Healthy
Interventions: Drug: AKB-6548 tablet, reference formulation given in the fasted state;   Drug: AKB-6548 tablet, test formulation given in the fasted state.;   Drug: AKB-6548 tablet, test formulation given in the fed state
13 Completed Effects of Ferrous Sulfate on the Pharmacokinetics of AKB-6548
Condition: Healthy Volunteers
Interventions: Drug: AKB-6548;   Drug: Ferrous Sulfate
14 Recruiting Efficacy and Safety Study to Evaluate Vadadustat for the Correction of Anemia in Subjects With Incident Dialysis-dependent Chronic Kidney Disease (DD-CKD)
Conditions: Anemia;   Dialysis-dependent Chronic Kidney Disease
Interventions: Drug: vadadustat;   Drug: Darbepoetin alfa

Study has passed its completion date and status has not been verified in more than two years.