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60 studies found for:    Tuberous Sclerosis
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Rank Status Study
21 Not yet recruiting Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis Complex
Conditions: Tuberous Sclerosis;   Angiofibroma;   Hypomelanotic Macule;   Plaque
Intervention: Drug: NPC-12G gel
22 Unknown  Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAM
Conditions: Tuberous Sclerosis;   Lymphangioleiomyomatosis
Intervention: Drug: sirolimus
23 Completed Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC)
Conditions: Tuberous Sclerosis;   Angiofibroma;   Hypomelanotic Macule;   Plaque
Interventions: Drug: NPC-12G gel;   Drug: Placebo gel
24 Recruiting Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex
Conditions: Tuberous Sclerosis Complex;   TSC Related Cognitive Disability;   TSC Related Autism;   TSC Related Learning Problems
Interventions: Drug: Everolimus;   Drug: Placebo
25 Completed Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)
Conditions: Tuberous Sclerosis;   Neurofibromatoses;   Angiofibroma;   Neurofibroma
Interventions: Drug: Skincerity;   Drug: Skincerity plus sirolimus/rapamycin;   Drug: Skinercity plus sirolimus/rapamycin
26 Recruiting Long-term, Prospective Study Evaluating Clinical and Molecular Biomarkers of Epileptogenesis in a Genetic Model of Epilepsy - Tuberous Sclerosis Complex
Conditions: TSC;   Tuberous Sclerosis Complex;   Epilepsy
Intervention: Device: epilepsy early diagnosis protocol
27 Recruiting A Randomized Controlled Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)
Conditions: Tuberous Sclerosis Complex;   Seizures
Interventions: Drug: GWP42003-P;   Drug: Placebo
28 Enrolling by invitation An Open-label Extension Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)
Conditions: Tuberous Sclerosis Complex;   Seizures
Intervention: Drug: GWP42003-P
29 Completed Tuberous Sclerosis Complex: Facial Angiofibroma Skin Cream
Condition: Facial Angiofibroma
Intervention: Drug: Rapamune
30 Not yet recruiting Topical Everolimus in Patients With Tuberous Sclerosis Complex
Condition: Facial Angiofibromas
Interventions: Drug: Everolimus;   Drug: Placebo
31 Terminated Sabril for Complex Partial Seizures in Adult Tolerability Study (TS) Patients
Condition: Complex Partial Seizures
Intervention: Drug: vigabatrin
32 Completed RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAM
Conditions: Tuberous Sclerosis;   Lymphangioleiomyomatosis
Intervention: Drug: RAD001
33 Not yet recruiting Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment
Condition: Tuberous Sclerosis Complex (TSC)
Intervention: Drug: everolimus
34 Completed Rapamycin In Angiomyolipomas In Patients With Tuberous Sclerosis
Condition: Angiomyolipoma
Intervention: Drug: Sirolimus
35 Recruiting Safety of Simvastatin in LAM and TSC
Conditions: Lymphangioleiomyomatosis;   Tuberous Sclerosis Complex
Intervention: Drug: Simvastatin
36 Active, not recruiting Potential EEG Biomarkers and Antiepileptogenic Strategies for Epilepsy in TSC
Condition: Tuberous Sclerosis Complex
Intervention:
37 Terminated Studies of Autistic Patients: Gene Networks and Clinical Subtypes
Conditions: Autism;   Tuberous Sclerosis
Intervention:
38 Completed Topical Rapamycin to Erase Angiofibromas in TSC
Conditions: Angiofibromas;   Tuberous Sclerosis
Interventions: Drug: Placebo;   Drug: Rapamycin
39 Completed Rapalogues for Autism Phenotype in TSC: A Feasibility Study
Conditions: Tuberous Sclerosis Complex;   Self-injury;   Autism
Interventions: Drug: Sirolimus;   Drug: Everolimus
40 Recruiting A Pilot Study To Evaluate The Effects of Everolimus on Brain mTOR Activity and Cortical Hyperexcitability in TSC and FCD
Conditions: Epilepsy;   Tuberous Sclerosis Complex;   Focal Cortical Dysplasia
Intervention: Drug: Everolimus

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Study has passed its completion date and status has not been verified in more than two years.