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363 studies found for:    Topotecan
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Rank Status Study
1 Completed Regulatory Hycamtin(Oral) PMS
Condition: Lung Cancer, Small Cell
Intervention: Drug: Topotecan
2 Recruiting Phase I Dose Escalation Study of Topotecan and Pazopanib in Children With Recurrent/Refractory Solid and CNS Tumours
Conditions: Solid Tumors;   Central Nervous System Tumors
Intervention: Drug: Topotecan and Pazopanib
3 Completed Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma
Conditions: Malignant Glioma;   WHO Grade III or IV Recurrent Glioma
Interventions: Drug: Topotecan;   Drug: Gadolinium DTPA;   Device: Cleveland Multiport Catheter
4 Terminated
Has Results
Topotecan With Erlotinib for Topotecan Pretreated Ovarian Cancer
Condition: Ovarian Cancer
Interventions: Drug: Topotecan;   Drug: Erlotinib
5 Completed
Has Results
Phase I, Dosage-finding and PK Study of IV Topotecan and Erlotinib With Refractory Solid Tumors
Condition: Metastatic Solid Tumor
Interventions: Drug: Topotecan;   Drug: Erlotinib
6 Completed
Has Results
Oral Topotecan to Treat Recurrent or Persistent Solid Tumors
Condition: Tumors
Intervention: Drug: Oral Topotecan
7 Completed Higher Dose Weekly Topotecan In The Treatment Of Patients With Extensive Stage Small-Cell Lung Cancer
Conditions: Small Cell Lung Cancer;   Carcinoma, Small Cell
Intervention: Drug: Topotecan
8 Recruiting Pazopanib and Weekly Topotecan in Patients Recurrent Ovarian Cancer (TOPAZ)
Condition: Ovarian Cancer
Intervention: Drug: pazopanib in combination with weekly topotecan
9 Completed A Phase I Topotecan Study in Subjects With Cancer and Impaired Renal Function
Condition: Lung Cancer, Small Cell
Intervention: Drug: Topotecan
10 Terminated Trial of High Dose Topotecan With Carboplatin in Patients With Relapsed Ovarian Carcinoma
Conditions: Ovarian Cancer;   Relapses
Intervention: Drug: Topotecan
11 Terminated ME-344 Given in Combination With Hycamtin® in Patients With Solid Tumors
Condition: Solid Tumors
Interventions: Drug: ME-344;   Drug: Topotecan
12 Completed Ph I Oral Topotecan and Temozolomide for Patients With Malignant Gliomas
Conditions: Glioblastoma;   Gliosarcoma;   Anaplastic Astrocytoma
Intervention: Drug: Oral Topotecan and Temodar
13 Recruiting Pembrolizumab vs Topotecan in Patients With Small Cell Lung Cancer
Condition: Small Cell Lung Cancer
Interventions: Drug: Topotecan;   Drug: Pembrolizumab
14 Recruiting Topotecan in Glioma Undergoing A Clinically-Indicated Surgical Resection
Conditions: Brain Tumor;   High Grade Glioma
Interventions: Drug: topotecan;   Device: Cleveland Multiport Catheter
15 Terminated Oral Topotecan As A Radiosensitizing Agent In Rectal Cancer
Condition: Rectal Cancer
Intervention: Drug: Hycamtin
16 Recruiting LCL161 Plus Topotecan for Patients With Relapsed/Refractory Small Cell Lung Cancer and Select Gynecologic Malignancies
Conditions: Small Cell Lung Cancer;   Ovarian Cancer
Interventions: Drug: LCL161;   Drug: Topotecan
17 Completed
Has Results
Topotecan and Bevacizumab in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer That Did Not Respond to Previous Systemic Chemotherapy
Condition: Lung Cancer
Interventions: Biological: bevacizumab;   Drug: topotecan hydrochloride
18 Completed Veliparib and Topotecan for Relapsed Ovarian Cancer With Negative or Unknown BRCA Status
Condition: Ovarian Cancer
Interventions: Drug: Veliparib;   Drug: Topotecan
19 Unknown  Phase II Trial of Chemotherapy With Temodar With Topotecan for CNS Metastasis of Solid Tumors
Conditions: Central Nervous System (CNS) Metastases;   Brain Metastases
Interventions: Drug: Topotecan;   Drug: Temozolomide
20 Terminated Efficacy of Topotecan and Lapatinib in Early Recurrent Ovarian or Peritoneal Cancer
Conditions: Cancer;   Ovarian;   Relapse;   Chemotherapy
Interventions: Drug: TOPOTECAN;   Drug: LAPATINIB

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Study has passed its completion date and status has not been verified in more than two years.